المؤلفون: S. Michael Owens, Elizabeth M. Laurenzana, Michael D. Hambuchen, John C Frank, Misty W Stevens, Sarah J. White, Howard P. Hendrickson, W. Brooks Gentry, D. Keith Williams

المصدر: Human Vaccines & Immunotherapeutics. 10:2638-2647

مصطلحات موضوعية: Male, Time Factors, medicine.drug_class, medicine.medical_treatment, Immunology, Pharmacology, Monoclonal antibody, Methamphetamine, Placebos, Rats, Sprague-Dawley, chemistry.chemical_compound, Pharmacokinetics, medicine, Animals, Immunology and Allergy, Binding site, Saline, Volume of distribution, Antibodies, Monoclonal, Meth, Dissociation constant, Disease Models, Animal, Treatment Outcome, chemistry, Drug Overdose, Locomotion, Research Paper, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4296f7bdd5007653f3de09580f1cc6d
https://doi.org/10.4161/hv.29707

المؤلفون: Tao Chen, Denise M. Coslo, Fengming Chen, Curtis J. Omiecinski, Elizabeth M. Laurenzana

المصدر: Biochemical Journal. 458:95-107

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Base Sequence, biology, Protein subunit, Ubiquitination, Receptors, Cytoplasmic and Nuclear, Cell Biology, Proteasome complex, Ligand (biochemistry), Biochemistry, Article, Cell Line, Cell biology, Cytosol, Proteasome, Ubiquitin, Constitutive androstane receptor, biology.protein, Animals, Humans, Receptor, Molecular Biology, Constitutive Androstane Receptor, DNA Primers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756664885d6683ece1dc0dd9f6a9f96c
https://doi.org/10.1042/bj20130685

المؤلفون: Denise M. Coslo, Elizabeth M. Laurenzana, M. Veronica Vigilar, Curtis J. Omiecinski, Anthony M. Roman

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Receptors, Steroid, Phthalic Acids, Receptors, Cytoplasmic and Nuclear, Biology, Toxicology, Article, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Internal medicine, Constitutive androstane receptor, medicine, Structure–activity relationship, Humans, Receptor, Cells, Cultured, Constitutive Androstane Receptor, Aged, Pregnane X receptor, Dose-Response Relationship, Drug, Molecular Structure, Alternative splicing, Phthalate, Pregnane X Receptor, General Medicine, Peroxisome, Middle Aged, 030104 developmental biology, Endocrinology, Nuclear receptor, chemistry, Hepatocytes, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a217a08483fd999ec8d3b03ea9c21279
https://europepmc.org/articles/PMC5144158/

المؤلفون: Malavika Kannuswamy, Brian E. Sell, Tao Chen, Yong Li, Stephen C. Strom, Curtis J. Omiecinski, Elizabeth M. Laurenzana

المصدر: Molecular Pharmacology. 82:918-928

مصطلحات موضوعية: Transcriptional Activation, Co-Repressor Proteins, Transcription, Genetic, Molecular Sequence Data, Primary Cell Culture, Receptors, Cytoplasmic and Nuclear, Biology, Transactivation, Genes, Reporter, Two-Hybrid System Techniques, Oximes, Constitutive androstane receptor, Humans, Immunoprecipitation, Protein Isoforms, Amino Acid Sequence, Luciferases, Receptor, Constitutive Androstane Receptor, Pharmacology, DAX-1 Orphan Nuclear Receptor, Activator (genetics), Oxidoreductases, N-Demethylating, Articles, Molecular biology, Cytochrome P-450 CYP2B6, Thiazoles, Nuclear receptor, Mutation, Hepatocytes, Molecular Medicine, Aryl Hydrocarbon Hydroxylases, Corepressor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d47de86b09ffbc5989e00aed93e41fe
https://doi.org/10.1124/mol.112.080721

المؤلفون: Richard C. Peffer, Tao Chen, Elizabeth M. Laurenzana, Curtis J. Omiecinski, Denise M. Coslo

المصدر: Toxicological Sciences. 123:550-562

مصطلحات موضوعية: Receptors, Cytoplasmic and Nuclear, Biology, Retinoid X receptor, Ligands, Toxicology, Mice, Dogs, Species Specificity, Molecular Toxicology, Constitutive androstane receptor, Animals, Humans, Protein Isoforms, RNA, Messenger, Receptor, Cells, Cultured, Constitutive Androstane Receptor, Regulation of gene expression, Effector, Alternative splicing, Sequence Analysis, DNA, Rats, Amino Acid Substitution, Gene Expression Regulation, Liver, Biochemistry, Nuclear receptor, Hepatocytes, RNA Splice Sites, Itraconazole, Sequence Alignment, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffacf38e60a53051dee349dd5d371c4c
https://doi.org/10.1093/toxsci/kfr191

المؤلفون: Tao Chen, Eric C. Peterson, Elizabeth M. Laurenzana, Joshua G. DeKeyser, Curtis J. Omiecinski

المصدر: Toxicological Sciences. 120:381-391

مصطلحات موضوعية: Receptors, Steroid, endocrine system, In silico, Blotting, Western, Cell Culture Techniques, Receptors, Cytoplasmic and Nuclear, Endocrine Disruptors, Biology, Ligands, Transfection, Toxicology, Transactivation, chemistry.chemical_compound, CYP2B6 Gene, Molecular Toxicology, Diethylhexyl Phthalate, Two-Hybrid System Techniques, Chlorocebus aethiops, Constitutive androstane receptor, Animals, Cytochrome P-450 CYP3A, Humans, Protein Isoforms, Receptor, Constitutive Androstane Receptor, Pregnane X receptor, Molecular Structure, Alternative splicing, Pregnane X Receptor, Phthalate, Oxidoreductases, N-Demethylating, Alternative Splicing, Cytochrome P-450 CYP2B6, Biochemistry, chemistry, Enzyme Induction, COS Cells, Hepatocytes, Aryl Hydrocarbon Hydroxylases, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9b32ae1eff5c80e04e5e6a0ea41956
https://doi.org/10.1093/toxsci/kfq394

المؤلفون: Curtis J. Omiecinski, Iain A. Murray, Colin A. Flaveny, Gary H. Perdew, Tejas S. Lahoti, Brett C. DiNatale, Elizabeth M. Laurenzana, Jennifer C. Schroeder

المصدر: Toxicological Sciences. 115:89-97

مصطلحات موضوعية: Agonist, Polychlorinated Dibenzodioxins, medicine.drug_class, Breast Neoplasms, Endogeny, Kynurenic Acid, Ligands, Toxicology, Gene Expression Regulation, Enzymologic, Immune tolerance, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Kynurenic acid, Molecular Toxicology, Cell Line, Tumor, Basic Helix-Loop-Helix Transcription Factors, Cytochrome P-450 CYP1A1, medicine, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, RNA, Messenger, Receptor, biology, Interleukin-6, Aryl hydrocarbon receptor, Ligand (biochemistry), Cell biology, Receptors, Aryl Hydrocarbon, chemistry, Biochemistry, Enzyme Induction, Hepatocytes, biology.protein, Environmental Pollutants, Female, Signal transduction, Excitatory Amino Acid Antagonists, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3399009aadc29415553cb764ff4b188c
https://doi.org/10.1093/toxsci/kfq024

المؤلفون: Keith W. Ward, David K. Williams, Howard P. Hendrickson, Sarah J. White, Samuel Michael Owens, Elizabeth M. Laurenzana, W.B. Gentry

المصدر: Toxicological Sciences. 111:27-36

مصطلحات موضوعية: medicine.medical_specialty, Dextroamphetamine, medicine.medical_treatment, Gestational Age, Motor Activity, Toxicology, Methamphetamine, Fetal Development, Rats, Sprague-Dawley, chemistry.chemical_compound, Fetus, Pharmacokinetics, Pregnancy, Internal medicine, medicine, Animals, Infusions, Intravenous, Saline, Biotransformation and Toxicokinetics, Dose-Response Relationship, Drug, business.industry, Brain, Gestational age, Blood Proteins, Meth, medicine.disease, Rats, Endocrinology, chemistry, Anesthesia, Gestation, Central Nervous System Stimulants, Female, Stereotyped Behavior, business, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f721b728fa85484b7010e2796452e30
https://doi.org/10.1093/toxsci/kfp127

المؤلفون: Elizabeth M. Laurenzana, Howard P. Hendrickson, William T. Atchley, S. Michael Owens, Eric C. Peterson

المصدر: Journal of Pharmacology and Experimental Therapeutics. 325:124-133

مصطلحات موضوعية: Male, medicine.drug_class, Dimer, Drug Evaluation, Preclinical, Immunoglobulin Variable Region, Monoclonal antibody, Article, Methamphetamine, Rats, Sprague-Dawley, chemistry.chemical_compound, Antibody Specificity, In vivo, medicine, Animals, Immunoglobulin Fragments, Pharmacology, biology, Chemistry, Antibodies, Monoclonal, Meth, Molecular biology, Rats, Monomer, Biochemistry, Toxicity, biology.protein, Molecular Medicine, Antibody, Dimerization, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0741a97f0310e5af03d5a548e84646
https://doi.org/10.1124/jpet.107.134395

المؤلفون: S. Michael Owens, Melinda G. Gunnell, Elizabeth M. Laurenzana, H. Marie Lacy

المصدر: International Immunopharmacology. 8:1-11

مصطلحات موضوعية: medicine.drug_class, Recombinant Fusion Proteins, Molecular Sequence Data, Immunology, Phencyclidine, Protein Engineering, Immunoglobulin light chain, Monoclonal antibody, Article, Mice, Chimera (genetics), Cell Line, Tumor, Complementary DNA, medicine, Animals, Humans, Immunology and Allergy, Amino Acid Sequence, Binding site, Pharmacology, Binding Sites, Hybridomas, Base Sequence, Chemistry, Immunogenicity, Antibodies, Monoclonal, Protein engineering, Molecular biology, Hallucinogens, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477e943272023176d730f0662f270c72
https://doi.org/10.1016/j.intimp.2007.09.020

المؤلفون: Elizabeth M. Laurenzana, S. Michael Owens, Howard P. Hendrickson

المصدر: The AAPS Journal. 8:E709-E717

مصطلحات موضوعية: Male, Analyte, Electrospray, Chromatography, Chemistry, Coefficient of variation, Pharmaceutical Science, Meth, Methamphetamine, Tandem mass spectrometry, Article, Rats, Rats, Sprague-Dawley, chemistry.chemical_compound, Tandem Mass Spectrometry, medicine, Animals, Tissue Distribution, Trichloroacetic acid, Active metabolite, Chromatography, Liquid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e64d1e1939009e5bb160cd50e6cc65
https://doi.org/10.1208/aapsj080480

المؤلفون: Elizabeth M. Laurenzana, Renata J. Berg, S. Michael Owens, Jeremy R. West, W. Brooks Gentry, D. Keith Williams, Teodora Terlea

المصدر: International Immunopharmacology. 6:968-977

مصطلحات موضوعية: Central Nervous System, Male, Immunology, Central nervous system, Hemodynamics, Blood Pressure, Motor Activity, Pharmacology, Cardiovascular System, Methamphetamine, Rats, Sprague-Dawley, chemistry.chemical_compound, Heart Rate, Heart rate, Animals, Immunology and Allergy, Medicine, Amphetamine, business.industry, Antibodies, Monoclonal, Meth, Rats, Blood pressure, medicine.anatomical_structure, chemistry, Toxicity, Central Nervous System Stimulants, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afd7cac37a285d1924dd42fd21fda75
https://doi.org/10.1016/j.intimp.2006.01.008

المؤلفون: William D. Wessinger, Howard P. Hendrickson, W. Brooks Gentry, S. Michael Owens, Elizabeth M. Laurenzana, Abid U Ghafoor

المصدر: Pharmacology Biochemistry and Behavior. 79:751-760

مصطلحات موضوعية: Male, medicine.medical_treatment, Clinical Biochemistry, Motor Activity, Pharmacology, Toxicology, Biochemistry, Methamphetamine, Rats, Sprague-Dawley, Behavioral Neuroscience, Route of administration, chemistry.chemical_compound, Pharmacokinetics, medicine, Animals, Amphetamine, Saline, Biological Psychiatry, Dose-Response Relationship, Drug, Meth, Rats, Dose–response relationship, Stereotypy (non-human), chemistry, Stereotyped Behavior, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bccfa0db388b34449e0824b32390c9
https://doi.org/10.1016/j.pbb.2004.10.006

المؤلفون: Elizabeth M. Laurenzana, Alessandra Milesi-Hallé, Howard P. Hendrickson, S.M Owens

المصدر: Journal of Chromatography B. 806:81-87

مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Analyte, Electrospray, Electrospray ionization, Clinical Biochemistry, Tandem mass spectrometry, Sensitivity and Specificity, Biochemistry, Methamphetamine, Analytical Chemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Pharmacokinetics, Animals, Solid phase extraction, Chromatography, Chemistry, Reproducibility of Results, Cell Biology, General Medicine, Meth, Rats, Amphetamine, Calibration, Female, Quantitative analysis (chemistry), Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65165316cd371174013a537295dc6309
https://doi.org/10.1016/j.jchromb.2004.03.038

المؤلفون: Elizabeth M. Laurenzana, S. Michael Owens, Reid D. Landes, Philip Abraham, Kelly Byrnes-Blake, W. Brooks Gentry, F. Ivy Carroll

المصدر: European Journal of Pharmacology. 461:119-128

مصطلحات موضوعية: Male, Time Factors, medicine.drug_class, medicine.medical_treatment, Motor Activity, Pharmacology, Monoclonal antibody, Methamphetamine, Rats, Sprague-Dawley, Mice, Pharmacokinetics, Antibody Specificity, medicine, Animals, Tissue Distribution, Antidote, Saline, Mice, Inbred BALB C, Chemistry, Antibodies, Monoclonal, Brain, Rats, Amphetamine, Area Under Curve, Pharmacodynamics, Monoclonal, Central Nervous System Stimulants, Female, Antagonism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db790c28ade927bfe8efe3f7e7329940
https://doi.org/10.1016/s0014-2999(03)01313-x

المؤلفون: William D. Wessinger, Galen R. Wenger, J. Shane Hardin, Elizabeth M. Laurenzana, Joel W. Proksch, S. Michael Owens

المصدر: Journal of Pharmacology and Experimental Therapeutics. 302:119-126

مصطلحات موضوعية: Male, medicine.drug_class, medicine.medical_treatment, Phencyclidine, Motor Activity, Pharmacology, Monoclonal antibody, Neuroprotection, Rats, Sprague-Dawley, Mice, In vivo, medicine, Animals, Humans, Antibodies, Blocking, Saline, Behavior, Animal, Dose-Response Relationship, Drug, biology, Chemistry, Antibodies, Monoclonal, Brain, Rats, Mechanism of action, Immunoglobulin G, Injections, Intravenous, Monoclonal, biology.protein, Molecular Medicine, Cattle, Indicators and Reagents, medicine.symptom, Antibody, Excitatory Amino Acid Antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da569e53f2a8b6538bda303b6e6c44c4
https://doi.org/10.1124/jpet.302.1.119

المؤلفون: Curtis J. Omiecinski, Xi Yang, Elizabeth M. Laurenzana

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::101776e9994c58bc50d8d0a75b046aa1
https://doi.org/10.1002/9780470921920.edm013

المؤلفون: Brian E. Sell, Yong Li, Elizabeth M. Laurenzana, Curtis J. Omiecinski, Tao Chen, Malavika Kannuswamy

المصدر: The FASEB Journal. 26

مصطلحات موضوعية: Orphan receptor, Transcriptional activity, Genetics, Biology, Molecular Biology, Biochemistry, Corepressor, Biotechnology, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2bc713d71ea3985f0558cc34b146421b
https://doi.org/10.1096/fasebj.26.1_supplement.673.5

المؤلفون: Elizabeth M. Laurenzana, S. Michael Owens, Howard P. Hendrickson, W. Brooks Gentry, Sarah J. White

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 39(9)

مصطلحات موضوعية: medicine.medical_treatment, Metabolite, Pharmaceutical Science, Gestational Age, Pharmacology, Methamphetamine, Rats, Sprague-Dawley, chemistry.chemical_compound, Pharmacokinetics, Pregnancy, medicine, Animals, Saline, Active metabolite, Dose-Response Relationship, Drug, business.industry, Half-life, Meth, Articles, Rats, Amphetamine, chemistry, Injections, Intravenous, Gestation, Pregnancy, Animal, Female, business, medicine.drug, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a764ff8dc4ee120a47054e64a840b726
https://pubmed.ncbi.nlm.nih.gov/21632964

المؤلفون: Elizabeth M. Laurenzana, Jonathan J. Hubbard, S.M. Owens, W.B. Gentry, David K. Williams

المصدر: International immunopharmacology. 11(12)

مصطلحات موضوعية: Offspring, Immunology, Physiology, Phencyclidine, Blood Pressure, Motor Activity, Article, Bolus (medicine), Heart Rate, Pregnancy, medicine, Immunology and Allergy, Animals, Fetal Death, Pharmacology, Fetus, business.industry, Pregnancy Outcome, Antibodies, Monoclonal, medicine.disease, Rats, Femoral Artery, Blood pressure, In utero, Anesthesia, Gestation, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73b22cd51d300851231a00938cfe306
https://pubmed.ncbi.nlm.nih.gov/22001428