المؤلفون: Robert P. Sheridan, J. Chris Culberson, Elizabeth Joshi, Matthew Tudor, Prabha Karnachi

المصدر: Journal of chemical information and modeling. 62(14)

مصطلحات موضوعية: General Chemical Engineering, Quantitative Structure-Activity Relationship, General Chemistry, Library and Information Sciences, Computer Science Applications

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701037575d8f7662625114930b4af51e
https://pubmed.ncbi.nlm.nih.gov/35796226

المؤلفون: Elizabeth Joshi, Andy Liaw, Prabha Karnachi, Meir Glick, Yuting Xu, Matthew Tudor, Robert P. Sheridan, Falgun Shah, Juan C. Alvarez, Alan C. Cheng

المصدر: Journal of Chemical Information and Modeling. 60:1969-1982

مصطلحات موضوعية: Quantitative structure–activity relationship, geography, geography.geographical_feature_category, 010304 chemical physics, Computer science, General Chemical Engineering, Uncertainty, Quantitative Structure-Activity Relationship, General Chemistry, Limiting, Library and Information Sciences, computer.software_genre, 01 natural sciences, Chemical space, 0104 chemical sciences, Computer Science Applications, Structure-Activity Relationship, 010404 medicinal & biomolecular chemistry, 0103 physical sciences, Cliff, Kurtosis, Scientific Experimental Error, Data mining, Noise (video), computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fa5563d4937fc0756adda0e983dd47
https://doi.org/10.1021/acs.jcim.9b01067

المؤلفون: Alan C. Cheng, Evan N. Feinberg, Vijay S. Pande, Elizabeth Joshi

المصدر: Journal of medicinal chemistry. 63(16)

مصطلحات موضوعية: Chemistry, Pharmaceutical, Datasets as Topic, Machine learning, computer.software_genre, 01 natural sciences, 03 medical and health sciences, Computational Chemistry, Deep Learning, Drug Discovery, Feature (machine learning), Leverage (statistics), Animals, Humans, Organic Chemicals, Representation (mathematics), 030304 developmental biology, 0303 health sciences, business.industry, Chemistry, Deep learning, Chemical space, 0104 chemical sciences, Random forest, 010404 medicinal & biomolecular chemistry, Cheminformatics, Molecular Medicine, Graph (abstract data type), Artificial intelligence, Supervised Machine Learning, business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5853683c51e01201b2ac1429ecacbcb8
https://pubmed.ncbi.nlm.nih.gov/32286824

المؤلفون: Xavier Fradera, Meredeth A. McGowan, Mangeng Cheng, Pravien Abeywickrema, Karin M. Otte, Prasanthi Geda, Nunzio Sciammetta, Catherine White, Konstanze von Köenig, Charles A. Lesburg, Hyun Chong Woo, Nadya Smotrov, Sarah E Trewick, Patrick J. Curran, Martin Augustin, Christine Andrews, Elizabeth Joshi, Wensheng Yu, Elliott B. Nickbarg, Phillip M. Cowley, Ian Knemeyer, Jongwon Lim, Hua Zhou, Yongxin Han, Xuelei Song, David Jonathan Bennett, Mee Ra Heo, Peter Spacciapoli, J. Richard Miller

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: 010405 organic chemistry, medicine.medical_treatment, Organic Chemistry, Pharmacology, Ligand (biochemistry), 01 natural sciences, Biochemistry, Immune checkpoint, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Immune system, chemistry, Cancer immunotherapy, Drug Discovery, medicine, Potency, Indoleamine 2,3-dioxygenase, Heme, Whole blood

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581b064473f176e3696647f1e7fc716c
https://europepmc.org/articles/PMC7153270/

المؤلفون: James I. Fells, John M. Sanders, Jason E. Imbriglio, Suen Linda M, Andrew M. Haidle, Abbas Walji, Elizabeth Joshi, William D. Shipe, Nunzio Sciammetta, Hakan Gunaydin, Tjerk Bueters, Andreas Verras, Robert P. Sheridan, J. Christopher Culberson, Brian E. Mattioni, Marc A. Labroli, Douglas C. Beshore

المصدر: Journal of Medicinal Chemistry. 60:6771-6780

مصطلحات موضوعية: 0301 basic medicine, Prioritization, Quantitative structure–activity relationship, Drug discovery, In silico, Computational biology, Biology, Bioinformatics, 03 medical and health sciences, 030104 developmental biology, Drug Discovery, High-Throughput Screening Assays, Molecular Medicine, Selection (genetic algorithm)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a5ecd2b8e8388b7de80afcd6aee440bc
https://doi.org/10.1021/acs.jmedchem.6b01577

المؤلفون: Lee-Yuh Pai, Aaron Corona, Harry R. Chobanian, John P. Felix, Matthew J. Clements, Karen Owens, Haifeng Tang, Brande Thomas-Fowlkes, Kathleen A. Sullivan, Alexander Pasternak, Caryn Hampton, Jessica Frie, Vincent Tong, Ron Ferguson, Jessica Liu, Birgit T. Priest, Barbara Pio, Yan Guo, Elizabeth Joshi, Nardos Teumelsan, Ling Xu, Martin Köhler, Joseph M. Metzger, Zach Guo, Kevin M. Maloney

المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1109-1114

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, hERG, Pharmaceutical Science, Diuresis, Biochemistry, Natriuresis, Sulfone, 03 medical and health sciences, chemistry.chemical_compound, Heterocyclic Compounds, Rats, Inbred SHR, Drug Discovery, medicine, Animals, Moiety, Organic chemistry, Sulfones, Enzyme Inhibitors, Potassium Channels, Inwardly Rectifying, Diuretics, Molecular Biology, biology, Chemistry, Organic Chemistry, Rats, 030104 developmental biology, Drug Design, ROMK, biology.protein, Molecular Medicine, Diuretic, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c5ab8a2efa0d6babaaad56a9277a67
https://doi.org/10.1016/j.bmcl.2016.10.032

المؤلفون: Elizabeth Joshi, Zhizhen Zeng, Joseph Della Rocca, David J. Schenk, Jeffrey L. Evelhoch, Idriss Bennacef, Abbas Walji, Hyking Haley, Mona Purcell, Kerry Riffel, Serena Xu, Marie A. Holahan, Paul J. Coleman, Eric D. Hostetler, Talakad G. Lohith, Aileen Soriano, Brett Connolly, Liza Gantert, Patricia Miller, Cristian Salinas, Xiaoping Zhang, Aimie Ogawa, David Hesk

المصدر: Journal of Nuclear Medicine. 57:1599-1606

مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Amyloid, Hippocampus, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, Radioactive Tracers, Binding selectivity, Radiochemistry, Chemistry, Brain, Neurofibrillary Tangles, Human brain, Isoquinolines, medicine.disease, Entorhinal cortex, Macaca mulatta, medicine.anatomical_structure, Positron-Emission Tomography, Autoradiography, Immunohistochemistry, Alzheimer's disease, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8733806d8e7d47383df5f2187ef2941
https://doi.org/10.2967/jnumed.115.171678

المؤلفون: Patricia Miller, Yaode Wang, Joseph Della Rocca, Jeffrey L. Evelhoch, Paul J. Coleman, Kerry Riffel, Zhizhen Zeng, Elizabeth Joshi, Kun Yang, Xiaoping Zhang, Kerim Babaoglu, Eric D. Hostetler, Talakad G. Lohith, Stacey O'Malley, David Hesk, Abbas Walji, Jaume Balsells, Mona Purcell, Jing Li, Serena Xu, Brett Connolly, Stacey Melquist, Arie Struyk, Jianmin Fu, Julie A. O'Brien, Marie A. Holahan, Harold G. Selnick, Fred Hess, Aimie Ogawa, David J. Schenk, Idriss Bennacef, Cristian Salinas, Joel B. Schachter, Aileen Soriano, Liza Gantert

المصدر: Journal of Medicinal Chemistry. 59:4778-4789

مصطلحات موضوعية: Fluorine Radioisotopes, Tau pathology, Tau protein, Nanotechnology, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, In vivo, Drug Discovery, medicine, Humans, Pet tracer, Molecular Structure, medicine.diagnostic_test, biology, Chemistry, Neurofibrillary Tangles, Pet imaging, Isoquinolines, Molecular Imaging, Positron emission tomography, Positron-Emission Tomography, New disease, Cancer research, biology.protein, Molecular Medicine, Amine gas treating, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39b60a8ba41ad44ebe7487bf9b6714d
https://doi.org/10.1021/acs.jmedchem.6b00166

المؤلفون: Gary Eichenbaum, Scott Q. Siler, Elizabeth Joshi, Paul B. Watkins, Brett A. Howell, Antonio Cabal, Hugh A. Barton

المصدر: Drug Discovery Today: Disease Models. 22:5-13

مصطلحات موضوعية: 0301 basic medicine, Knowledge management, Systems toxicology, business.industry, 030226 pharmacology & pharmacy, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Human disease, Drug development, Drug Discovery, Molecular Medicine, Model development, business, Platform development, Simulation, Systems pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::20319285ff230804eaff93b32306c0b5
https://doi.org/10.1016/j.ddmod.2017.04.001

المؤلفون: Robert Houle, Elizabeth Joshi, Prabha Karnachi, Michael J. Hafey

المصدر: Drug Metabolism and Pharmacokinetics. 33:S64-S65

مصطلحات موضوعية: Pharmacology, Computer science, In silico, Pharmaceutical Science, Pharmacology (medical), Computational biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c979d60b8ee66f14af5819f68cd194da
https://doi.org/10.1016/j.dmpk.2017.11.216

المؤلفون: Elizabeth Joshi

المصدر: Bioanalysis. 3:1317-1318

مصطلحات موضوعية: Medical Laboratory Technology, Drug development, Political science, Clinical Biochemistry, Engineering ethics, General Medicine, General Pharmacology, Toxicology and Pharmaceutics, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::523e5f629a853fe74fd2586bd599119c
https://doi.org/10.4155/bio.11.115