المؤلفون: Herwig Grimm, Nikola Biller-Andorno, Thorsten Buch, Maik Dahlhoff, Gail Davies, Christopher R. Cederroth, Otto Maissen, Wilma Lukas, Elisa Passini, Elin Törnqvist, I. Anna S. Olsson, Jenny Sandström

المصدر: Frontiers in Veterinary Science, Vol 10 (2023)

مصطلحات موضوعية: animal research, 3Rs, innovation, implementation, ethics, Veterinary medicine, SF600-1100

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fvets.2023.1185706/full; https://doaj.org/toc/2297-1769

URL الوصول: https://doaj.org/article/e9d2ba6a12be4ddd801056e43d49c605

المؤلفون: Annie Delaunois, François‐Xavier Mathy, Miranda Cornet, Vitalina Gryshkova, Chloé Korlowski, François Bonfitto, Juliane Koch, Anne‐Françoise Schlit, Simon Hebeisen, Elisa Passini, Blanca Rodriguez, Jean‐Pierre Valentin

المصدر: Pharmacology Research & Perspectives, Vol 11, Iss 1, Pp n/a-n/a (2023)

مصطلحات موضوعية: cardiac safety, CiPA, ICH S7B, levetiracetam, nonclinical, QT prolongation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2052-1707

URL الوصول: https://doaj.org/article/8e3d0b97aa3843f1ab02c7d3ae9a2afc

المؤلفون: Cristian Trovato, Marcel Mohr, Friedemann Schmidt, Elisa Passini, Blanca Rodriguez

المصدر: Frontiers in Toxicology, Vol 4 (2022)

مصطلحات موضوعية: in silico trials, cardiac electrophysiology, computer modelling, drug safety, purkinje fibre, cardiac arrythmia, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2022.992650/full; https://doaj.org/toc/2673-3080

URL الوصول: https://doaj.org/article/51480fe6bfe54fbd80a1a0a0cdb1b93d

المؤلفون: Annie Delaunois, Matthew Abernathy, Warren D. Anderson, Kylie A. Beattie, Khuram W. Chaudhary, Julie Coulot, Vitalina Gryshkova, Simon Hebeisen, Mark Holbrook, James Kramer, Yuri Kuryshev, Derek Leishman, Isabel Lushbough, Elisa Passini, Will S. Redfern, Blanca Rodriguez, Eric I. Rossman, Cristian Trovato, Caiyun Wu, Jean‐Pierre Valentin

المصدر: Clinical and Translational Science, Vol 14, Iss 3, Pp 1133-1146 (2021)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

URL الوصول: https://doaj.org/article/d703d6568c29415c8e2d93ccf47af5d0

المؤلفون: Michelangelo Paci, Jussi T. Koivumäki, Hua Rong Lu, David J. Gallacher, Elisa Passini, Blanca Rodriguez

المصدر: Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: human stem cell-derived cardiomyocyte, action potential, calcium transient, in silico modeling, drug test, sensitivity analysis, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.604713/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/887579600c5947f08a8e40d87d810b2f

المؤلفون: Chiara Bartolucci, Elisa Passini, Jari Hyttinen, Michelangelo Paci, Stefano Severi

المصدر: Frontiers in Physiology, Vol 11 (2020)

مصطلحات موضوعية: computational modeling, human ventricular action potential, population of models, calcium handling, extracellular concentrations, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2020.00314/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/9e6c406c13a5451ba4329300574c014f

المؤلفون: Xin Zhou, Yusheng Qu, Elisa Passini, Alfonso Bueno-Orovio, Yang Liu, Hugo M. Vargas, Blanca Rodriguez

المصدر: Frontiers in Pharmacology, Vol 10 (2020)

مصطلحات موضوعية: Torsades de Pointes, drug cardiotoxicity, ion channels, in silico drug trials, human ventricular action potential, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.01643/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/d694ae4a55bd4648a4708db5641899a3

المؤلفون: Jakub Tomek, Alfonso Bueno-Orovio, Elisa Passini, Xin Zhou, Ana Minchole, Oliver Britton, Chiara Bartolucci, Stefano Severi, Alvin Shrier, Laszlo Virag, Andras Varro, Blanca Rodriguez

المصدر: eLife, Vol 8 (2019)

مصطلحات موضوعية: computer simulations, heart, ventricular myocyte, calibration validation, computational biology, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/48890; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/4e46b2e40b74423396e56c74c81f1f62

المؤلفون: Elisa Passini, Oliver J. Britton, Hua Rong Lu, Jutta Rohrbacher, An N. Hermans, David J. Gallacher, Robert J. H. Greig, Alfonso Bueno-Orovio, Blanca Rodriguez

المصدر: Frontiers in Physiology, Vol 8 (2017)

مصطلحات موضوعية: in silico drug trials, drug safety, drug cardiotoxicity, Torsade de Pointes, computer models, human ventricular action potential, Physiology, QP1-981

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fphys.2017.00668/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/e99a42ad86a2401cb87ae68c3079f894

المؤلفون: Alfonso Bueno-Orovio, Blanca Rodriguez, Elisa Passini, Oliver J Britton

المصدر: Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2018, :PO4-34

المؤلفون: Chiara Bartolucci, Elisa Passini, Jari Hyttinen, Michelangelo Paci, Stefano Severi

مصطلحات موضوعية: Physiology, Exercise Physiology, Nutritional Physiology, Reproduction, Cell Physiology, Systems Physiology, Animal Physiology - Biophysics, Animal Physiology - Cell, Animal Physiology - Systems, Comparative Physiology, Physiology not elsewhere classified, computational modeling, human ventricular action potential, population of models, calcium handling, extracellular concentrations

Relation: https://figshare.com/articles/presentation/Presentation_1_Simulation_of_the_Effects_of_Extracellular_Calcium_Changes_Leads_to_a_Novel_Computational_Model_of_Human_Ventricular_Action_Potential_With_a_Revised_Calcium_Handling_pdf/12128205

الاتاحة: https://doi.org/10.3389/fphys.2020.00314.s001
https://figshare.com/articles/presentation/Presentation_1_Simulation_of_the_Effects_of_Extracellular_Calcium_Changes_Leads_to_a_Novel_Computational_Model_of_Human_Ventricular_Action_Potential_With_a_Revised_Calcium_Handling_pdf/12128205

المؤلفون: Jakub Tomek, Alfonso Bueno-Orovio, Elisa Passini, Xin Zhou, Ana Minchole, Oliver Britton, Chiara Bartolucci, Stefano Severi, Alvin Shrier, Laszlo Virag, Andras Varro, Blanca Rodriguez

Relation: url:https://www.openaccessrepository.it/communities/itmirror; https://www.openaccessrepository.it/record/72156

الاتاحة: https://www.openaccessrepository.it/record/72156
https://doi.org/10.7554/elife.48890.sa2

المؤلفون: Cristian Trovato, Marcel Mohr, Friedemann Schmidt, Elisa Passini, Blanca Rodriguez

مصطلحات موضوعية: Pharmacology, Toxicology, Immunology, Toxicology (incl. Clinical Toxicology), Nanotoxicology, Health and Safety, in silico trials, cardiac electrophysiology, computer modelling, drug safety, purkinje fibre, cardiac arrythmia, cardiac action potential, hERG

Relation: https://figshare.com/articles/dataset/Table1_Cross_clinical-experimental-computational_qualification_of_in_silico_drug_trials_on_human_cardiac_purkinje_cells_for_proarrhythmia_risk_prediction_XLSX/21274722

الاتاحة: https://doi.org/10.3389/ftox.2022.992650.s001
https://figshare.com/articles/dataset/Table1_Cross_clinical-experimental-computational_qualification_of_in_silico_drug_trials_on_human_cardiac_purkinje_cells_for_proarrhythmia_risk_prediction_XLSX/21274722

المؤلفون: Leto L Riebel, Elisa Passini, Francesca Margara, Michelangelo Paci, Jacopo Biasetti, Blanca Rodriguez

المصدر: 2021 Computing in Cardiology (CinC).

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f49e21f6fc26837aaf68f9e07187d157
https://doi.org/10.23919/cinc53138.2021.9662683

المؤلفون: Adam P. Hill, Zhen Song, Haibo Ni, Norman Stockbridge, David G. Strauss, Jamie I. Vandenberg, Todd Wisialowski, Mikiko Nakamura, Takashi Yoshinaga, Godfrey L. Smith, Jill Steidl‐Nichols, Mark Holbrook, Stefano Severi, Pierre Morissette, Derek J. Leishman, Colleen E. Clancy, Gary R. Mirams, Andrea Greiter-Wilke, Andrew G. Edwards, Xiaomei Han, Zhihua Li, Flora Musuamba Tshinanu, Stefano Morotti, Stephane Nave, Aaron Fullerton, Bradley J. Ridder, Zhilin Qu, Michelangelo Paci, Alfonso Bueno-Orovio, Janell E. Chen, Thomas Singer, Peter R. Kowey, Liudmila Polonchuk, Eric A. Sobie, Blanca Rodriguez, Randall L. Rasmusson, Elisa Passini, Eleonora Grandi, Ken Wang, Michael Liu, Bruce P. Damiano, Xin Zhou

المساهمون: Li Z., Mirams G.R., Yoshinaga T., Ridder B.J., Han X., Chen J.E., Stockbridge N.L., Wisialowski T.A., Damiano B., Severi S., Morissette P., Kowey P.R., Holbrook M., Smith G., Rasmusson R.L., Liu M., Song Z., Qu Z., Leishman D.J., Steidl-Nichols J., Rodriguez B., Bueno-Orovio A., Zhou X., Passini E., Edwards A.G., Morotti S., Ni H., Grandi E., Clancy C.E., Vandenberg J., Hill A., Nakamura M., Singer T., Polonchuk L., Greiter-Wilke A., Wang K., Nave S., Fullerton A., Sobie E.A., Paci M., Musuamba Tshinanu F., Strauss D.G., Tampere University, BioMediTech, Research group: Computational Biophysics and Imaging Group

المصدر: Clinical pharmacology and therapeutics, vol 107, iss 1
Clinical Pharmacology and Therapeutics

مصطلحات موضوعية: Drug-Related Side Effects and Adverse Reactions, none, In silico, White Paper, Harmonization, Context (language use), Arrhythmias, Validation Studies as Topic, Risk prediction models, Risk Assessment, 030226 pharmacology & pharmacy, Session (web analytics), 03 medical and health sciences, 0302 clinical medicine, Consistency (negotiation), White paper, Theoretical, Models, medicine, Humans, Computer Simulation, Pharmacology (medical), Pharmacology & Pharmacy, Pharmacology, Proarrhythmia, Management science, Arrhythmias, Cardiac, 217 Medical engineering, Pharmacology and Pharmaceutical Sciences, Models, Theoretical, medicine.disease, 030220 oncology & carcinogenesis, Cardiac

وصف الملف: application/pdf; ELETTRONICO; fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2ff4e1c2fbbbeb607662c3df93ed0e
https://doi.org/10.1002/cpt.1647

المؤلفون: Francesca Margara, Elisa Passini, Blanca Rodriguez

المصدر: EP Europace. 23

مصطلحات موضوعية: Drug, business.industry, Physiology (medical), media_common.quotation_subject, Medicine, Cardiology and Cardiovascular Medicine, business, Electro mechanics, Biomedical engineering, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d299b596a52875385883acca95142ae3
https://doi.org/10.1093/europace/euab116.513

المؤلفون: Hua Rong Lu, Michelangelo Paci, David J. Gallacher, Blanca Rodriguez, Jussi T. Koivumäki, Elisa Passini

المساهمون: Tampere University, BioMediTech

المصدر: Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Drug, drug test, media_common.quotation_subject, In silico, Drug action, 030204 cardiovascular system & hematology, Pharmacology, in silico modeling, 03 medical and health sciences, 0302 clinical medicine, action potential, sensitivity analysis, medicine, Nisoldipine, Repolarization, Pharmacology (medical), Original Research, media_common, Chemistry, lcsh:RM1-950, 217 Medical engineering, Drug application, In vitro, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, human stem cell-derived cardiomyocyte, calcium transient, Stem cell, medicine.drug

وصف الملف: fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec95646b8b9f27045ccc536a301ec317
https://www.frontiersin.org/articles/10.3389/fphar.2021.604713/full

المؤلفون: Elisa Passini, Simonetta Genovesi, Stefano Severi

المصدر: Computational and Mathematical Methods in Medicine, Vol 2014 (2014)

مصطلحات موضوعية: Computer applications to medicine. Medical informatics, R858-859.7

Relation: http://dx.doi.org/10.1155/2014/291598; https://doaj.org/toc/1748-670X; https://doaj.org/toc/1748-6718; https://doaj.org/article/ce2e04b09db14a59bc217f59ccd9f2b6

الاتاحة: https://doi.org/10.1155/2014/291598
https://doaj.org/article/ce2e04b09db14a59bc217f59ccd9f2b6

المؤلفون: Isabel Lushbough, Jean-Pierre Valentin, Vitalina Gryshkova, Simon Hebeisen, Cristian Trovato, Will S. Redfern, Khuram W. Chaudhary, Caiyun Wu, Eric I. Rossman, Kylie A. Beattie, Julie Coulot, Elisa Passini, Yuri A. Kuryshev, Warren D. Anderson, Blanca Rodriguez, Annie Delaunois, Derek J. Leishman, Matthew M. Abernathy, James Kramer, Mark Holbrook

المصدر: Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 3, Pp 1133-1146 (2021)

مصطلحات موضوعية: 030213 general clinical medicine, Pharmacology, 030226 pharmacology & pharmacy, Ion Channels, chloroquine, Electrocardiography, 0302 clinical medicine, Chloroquine, immune system diseases, Torsades de Pointes, hERG, General Pharmacology, Toxicology and Pharmaceutics, skin and connective tissue diseases, Proarrhythmia, azithromycin, education.field_of_study, biology, General Neuroscience, In vitro toxicology, General Medicine, Articles, 3. Good health, erythromycin, Public aspects of medicine, RA1-1270, medicine.drug, musculoskeletal diseases, hydroxychloroquine, Population, Torsades de pointes, RM1-950, QT prolongation, CHO Cells, QT interval, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Antimalarials, Cricetulus, COVID‐19, medicine, Animals, Humans, education, IC50, Dose-Response Relationship, Drug, business.industry, SARS-CoV-2, Arrhythmias, Cardiac, Off-Label Use, medicine.disease, COVID-19 Drug Treatment, CiPA, biology.protein, Therapeutics. Pharmacology, cardiac safety, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581ff6229742ba87f71f81a342b9f06c
http://europepmc.org/articles/PMC8014548

المؤلفون: S. Billiald-Desquand, Elisa Passini, C. Dusserre, Cristian Trovato, Blanca Rodriguez

المصدر: CinC

مصطلحات موضوعية: 0301 basic medicine, Drug, Purkinje fibres, Chemistry, media_common.quotation_subject, In silico, Dofetilide, 030204 cardiovascular system & hematology, Pharmacology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine, Verapamil, Diltiazem, Early phase, media_common, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b225955d0b6bae4443e90bc74b8cf9e0
https://doi.org/10.22489/cinc.2020.361