المؤلفون: Herschel S Dhekne, Francesca Tonelli, Wondwossen M Yeshaw, Claire Y Chiang, Charles Limouse, Ebsy Jaimon, Elena Purlyte, Dario R Alessi, Suzanne R Pfeffer

المصدر: eLife, Vol 12 (2023)

مصطلحات موضوعية: Parkinson's disease, Rab GTPase, kinase, lysosome stress, LRRK2, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/87098; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/3565c7f6dcf745449d8d8cc68bd1cf97

المؤلفون: Edmundo G Vides, Ayan Adhikari, Claire Y Chiang, Pawel Lis, Elena Purlyte, Charles Limouse, Justin L Shumate, Elena Spínola-Lasso, Herschel S Dhekne, Dario R Alessi, Suzanne R Pfeffer

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: LRRK2 kinase, Rab GTPase, Parkinson's disease, membrane microdomain, feed-forward pathway, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/79771; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/3925beaf71f0417ebbc0fd002e21efb5

المؤلفون: Alexia Kalogeropulou, Elena Purlyte, Francesca Tonelli, Dario Alessi

Relation: https://zenodo.org/communities/asaphub; https://doi.org/10.5281/zenodo.6401193; https://doi.org/10.5281/zenodo.6401194; oai:zenodo.org:6401194

الاتاحة: https://doi.org/10.5281/zenodo.6401194

المؤلفون: Alexia Kalogeropulou, Elena Purlyte, Francesca Tonelli, Dario Alessi

Relation: https://zenodo.org/communities/asaphub; https://doi.org/10.5281/zenodo.6401193; https://doi.org/10.5281/zenodo.6896851; oai:zenodo.org:6896851

الاتاحة: https://doi.org/10.5281/zenodo.6896851

المؤلفون: Alexia F Kalogeropulou, Elena Purlyte, Francesca Tonelli, Sven M Lange, Melanie Wightman, Alan R Prescott, Shalini Padmanabhan, Esther Sammler, Dario R Alessi

المصدر: Biochemical Journal. 479:1759-1783

مصطلحات موضوعية: Mutation, Humans, Parkinson Disease, Cell Biology, Phosphorylation, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Microtubules, Molecular Biology, Biochemistry, Protein Binding, nervous system diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f82d9a21bd9f7ecf1307b07c9768b6d
https://doi.org/10.1042/bcj20220161

المؤلفون: Herschel S. Dhekne, Francesca Tonelli, Wondwossen M. Yeshaw, Claire Y. Chiang, Charles Limouse, Ebsy Jaimon, Elena Purlyte, Dario R. Alessi, Suzanne R. Pfeffer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3257f216220943444e2beacd3afcc126
https://doi.org/10.1101/2023.02.17.529028

المؤلفون: Edmundo G Vides, Ayan Adhikari, Claire Y Chiang, Pawel Lis, Elena Purlyte, Charles Limouse, Justin L Shumate, Elena Spínola-Lasso, Herschel S Dhekne, Dario R Alessi, Suzanne R Pfeffer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d5529d608bd60d4f0daa33683392c225
https://doi.org/10.7554/elife.79771.sa2

المؤلفون: Mark Dorward, Elena Purlyte, Deep Chatterjee, Dario R. Alessi, Stefan Knapp, Raja Sekhar Nirujogi, Robert Gourlay, Pawel Lis, Matthew Taylor, Simone Weidlich, Sebastian Mathea, Francesca Tonelli, Rachel Toth, Nicole K. Polinski, Asad U. Malik, Athanasios Karapetsas, Prosenjit Pal

المصدر: Biochemical Journal

مصطلحات موضوعية: kinase, GTPase, Protein Serine-Threonine Kinases, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Biochemistry, Cell Line, Mice, Phosphoserine, 03 medical and health sciences, 0302 clinical medicine, Biochemical Techniques & Resources, Phosphoprotein Phosphatases, Animals, Humans, leucine rich repeat kinase, Amino Acid Sequence, Phosphorylation, RNA, Small Interfering, Kinase activity, Molecular Biology, Research Articles, Adaptor Proteins, Signal Transducing, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Post-Translational Modifications, Sequence Homology, Amino Acid, Effector, Chemistry, Kinase, Cell Biology, Fibroblasts, LRRK2, Recombinant Proteins, Signaling, Specific Pathogen-Free Organisms, nervous system diseases, Cell biology, RAB7A, rab GTP-Binding Proteins, Tetradecanoylphorbol Acetate, Rab, Protein Kinases, Protein Processing, Post-Translational, Sequence Alignment, Rab GTPase, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ff0a4cc22d633baeab820c0db4067a
https://doi.org/10.1042/bcj20200937

المؤلفون: Elena Purlyte, Amir R. Khan, Dieter Waschbüsch

المصدر: Biophysical journal. 120(9)

مصطلحات موضوعية: Coiled coil, 0303 health sciences, Chemistry, Effector, Biophysics, Parkinson Disease, GTPase, Arginine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Cell biology, 03 medical and health sciences, 0302 clinical medicine, rab GTP-Binding Proteins, Ciliogenesis, Organelle, Phosphorylation, Humans, Rab, Salt bridge, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e18b41e50fd0160498c3662cb3a349
https://pubmed.ncbi.nlm.nih.gov/33887226

المؤلفون: Elena Purlyte, Sebastian Mathea, Prosenjit Pal, Dario R. Alessi, Matthew Taylor, Robert Gourlay, Nicole K. Polinski, Stefan Knapp, Mark Dorward, Athanasios Karapetsas, Simone Weidlich, Asad U. Malik, Pawel Lis, Rachel Toth, Raja Sekhar Nirujogi, Francesca Tonelli

مصطلحات موضوعية: RAB7A, Growth factor receptor, Chemistry, Effector, Phosphorylation, GTPase, Rab, Kinase activity, LRRK2, nervous system diseases, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::49a662333b261aee7debbefeee175b7e
https://doi.org/10.1101/2020.11.25.397836

المؤلفون: Herschel S. Dhekne, Elena Purlyte, Rachel C Gomez, Pawel Lis, Melanie Wightman, Adil R. Sarhan, Suzanne R. Pfeffer, Francesca Tonelli, Dario R. Alessi, Terina N. Martinez

المصدر: The EMBO Journal

مصطلحات موضوعية: 0301 basic medicine, GTP', PARK genes, GTPase, Biology, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Golgi, Animals, Humans, Molecular Biology of Disease, Membrane & Intracellular Transport, Phosphorylation, Kinase activity, Molecular Biology, Cells, Cultured, 030304 developmental biology, 0303 health sciences, General Immunology and Microbiology, Kinase, General Neuroscience, Post-translational Modifications, Proteolysis & Proteomics, Parkinson Disease, Articles, Fibroblasts, LRRK2, nervous system diseases, Cell biology, Mice, Inbred C57BL, rab1 GTP-Binding Proteins, HEK293 Cells, 030104 developmental biology, rab GTP-Binding Proteins, Rab10, Rab, CRISPR-Cas Systems, Signal transduction, Corrigendum, 030217 neurology & neurosurgery, HeLa Cells, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae0c09504e8fb5ff319a52c83d0219a
https://doi.org/10.15252/embj.201798099

المؤلفون: Emma McGrath, Elena Purlyte, Amir R. Khan, Dieter Waschbüsch, Prosenjit Pal, Dario R. Alessi

مصطلحات موضوعية: 0303 health sciences, Effector, Kinase, Chemistry, GTPase, Heterotetramer, LRRK2, 3. Good health, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Phosphorylation, Rab, 030217 neurology & neurosurgery, 030304 developmental biology, Binding domain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0ec11dd9a5fb2ea2ffed94435e4b16

المؤلفون: Elena Purlyte, Dieter Waschbüsch, Dario R. Alessi, Amir R. Khan, Prosenjit Pal, Emma McGrath

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Serine, Effector, Chemistry, Kinase, Phosphorylation, Rab, GTPase, Heterotetramer, Cell biology, Binding domain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a45486c940507b408fe787836d78bce0
https://doi.org/10.2139/ssrn.3451451

المؤلفون: Prosenjit Pal, Dario R. Alessi, Dieter Waschbüsch, Elena Purlyte, Emma McGrath, Amir R. Khan

المصدر: Structure(London, England:1993)

مصطلحات موضوعية: Protein Conformation, alpha-Helical, JNK-interacting protein 3 and 4, GTPase, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Article, Phosphates, Serine, 03 medical and health sciences, Structural Biology, Ciliogenesis, Humans, Phosphorylation, Molecular Biology, 030304 developmental biology, Adaptor Proteins, Signal Transducing, Rab8a GTPase, 0303 health sciences, Binding Sites, RILP-like protein 2, Chemistry, Effector, membrane trafficking, 030302 biochemistry & molecular biology, Parkinson Disease, LRRK2, Heterotetramer, LRRK2 kinase, Cell biology, Molecular Docking Simulation, HEK293 Cells, effector, rab GTP-Binding Proteins, Rab, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f9958fe003bd66b502f4ae3a696478
http://europepmc.org/articles/PMC7139218