المؤلفون: Marloes A. H. M. Michels, Elena B. Volokhina, Nicole C. A. J. van de Kar, Lambertus P.W. J. van den Heuvel

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: nephritic factor, complement system, complement dysregulation, complement alternative pathway, assay standardization, C3 glomerulopathy, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036136/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/7e09eefc2a954f0190b874c0085fbf9e

المؤلفون: Sarah de Jong, Anita de Breuk, Bjorn Bakker, Suresh Katti, Carel B. Hoyng, Sara C. Nilsson, Anna M. Blom, Lambert P. van den Heuvel, Anneke I. den Hollander, Elena B. Volokhina

المصدر: Frontiers in Immunology, Vol 12 (2022)

مصطلحات موضوعية: complement factor I, genetic variants, age-related macular degeneration, atypical hemolytic uremic syndrome, functional analysis, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.789897/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/134adb6a67974b3ea7d273245b6c434f

المؤلفون: Marloes A. H. M. Michels, Nicole C. A. J. van de Kar, Sanne A. W. van Kraaij, Sebastian A. Sarlea, Valentina Gracchi, Flore A. P. T. Engels, Eiske M. Dorresteijn, Johannes van der Deure, Caroline Duineveld, Jack F. M. Wetzels, Lambertus P. W. J. van den Heuvel, Elena B. Volokhina

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: C3 glomerulopathy, classical complement pathway, autoantibody, C3 convertase, C4 nephritic factors (C4NeFs), C3 nephritic factors (C3NeFs), Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.715704/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/c4a4b7400a974a3880c33972d9baf64e

المؤلفون: Romy N. Bouwmeester, Mendy Ter Avest, Kioa L. Wijnsma, Caroline Duineveld, Rob ter Heine, Elena B. Volokhina, Lambertus P. W. J. Van Den Heuvel, Jack F. M. Wetzels, Nicole C. A. J. van de Kar

المصدر: Frontiers in Immunology, Vol 11 (2021)

مصطلحات موضوعية: atypical hemolytic uremic syndrome, aHUS, eculizumab, therapeutic drug monitoring, pharmacokinetic, proteinuria, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.612706/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/23408f3b87bb415c8e88c8a8caae52f7

المؤلفون: Kioa L. Wijnsma, Susan T. Veissi, Sem de Wijs, Thea van der Velden, Elena B. Volokhina, Frank A. D. T. G. Wagener, Nicole. C. A. J. van de Kar, L. P. van den Heuvel

المصدر: Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: heme, hemopexin, STEC-HUS, TMA, HO-1, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.547406/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/22ef7c8852a84e8f8cab9fc3c37f1547

المؤلفون: Marloes A. H. M. Michels, Nicole C. A. J. van de Kar, Ramon M. van den Bos, Thea J. A. M. van der Velden, Sanne A. W. van Kraaij, Sebastian A. Sarlea, Valentina Gracchi, Michiel J. S. Oosterveld, Elena B. Volokhina, Lambertus P. W. J. van den Heuvel

المصدر: Frontiers in Immunology, Vol 10 (2019)

مصطلحات موضوعية: complement system, alternative pathway, convertase, properdin, C3 nephritic factor, C3 glomerulopathy, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.01350/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/d1c7b4a3090e49a8a90d6ce8788aba70

المؤلفون: Elena B. Volokhina, Wouter J. C. Feitz, Lonneke M. Elders, Thea J. A. M. van der Velden, Nicole C. A. J. van de Kar, Lambertus P. W. J. van den Heuvel

المصدر: Toxins, Vol 12, Iss 7, p 435 (2020)

مصطلحات موضوعية: hemolytic uremic syndrome, human glomerular microvascular endothelium, Shiga toxin 1, gene expression, heparan sulfate proteoglycans, syndecan-4, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/12/7/435; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/0426338df34e4197bdda8c3d329f49cb

المؤلفون: Marloes A. H. M. Michels, Nicole C. A. J. van de Kar, Marcin Okrój, Anna M. Blom, Sanne A. W. van Kraaij, Elena B. Volokhina, Lambertus P. W. J. van den Heuvel

المصدر: Frontiers in Immunology, Vol 9 (2018)

مصطلحات موضوعية: complement system, alternative pathway, convertase, C3 nephritic factor, C3 glomerulopathy, atypical hemolytic uremic syndrome, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2018.00612/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/9832ab6399c24348b702a291a129e936

المؤلفون: Marloes A. H. M. Michels, Nicole C. A. J. van de Kar, Ramon M. van den Bos, Thea J. A. M. van der Velden, Sanne A. W. van Kraaij, Sebastian A. Sarlea, Valentina Gracchi, Michiel J. S. Oosterveld, Elena B. Volokhina, Lambertus P. W. J. van den Heuvel

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, complement system, alternative pathway, convertase, properdin, C3 nephritic factor, C3 glomerulopathy, therapy, Salp20

Relation: https://figshare.com/articles/presentation/Presentation_1_Novel_Assays_to_Distinguish_Between_Properdin-Dependent_and_Properdin-Independent_C3_Nephritic_Factors_Provide_Insight_Into_Properdin-Inhibiting_Therapy_PPTX/8283545

الاتاحة: https://doi.org/10.3389/fimmu.2019.01350.s001
https://figshare.com/articles/presentation/Presentation_1_Novel_Assays_to_Distinguish_Between_Properdin-Dependent_and_Properdin-Independent_C3_Nephritic_Factors_Provide_Insight_Into_Properdin-Inhibiting_Therapy_PPTX/8283545

المؤلفون: Elena B. Volokhina, Nicole C. A. J. van de Kar, Marloes A. H. M. Michels, Thea J A M van der Velden, Rianne J. F. Maas, Lambertus P. van den Heuvel

المصدر: Journal of Immunology, 207, 2465-2472
Journal of Immunology, 207, 10, pp. 2465-2472

مصطلحات موضوعية: Complement Pathway, Alternative, Immunology, chemical and pharmacologic phenomena, Complement C3-C5 Convertases, Complement Membrane Attack Complex, Cleavage (embryo), urologic and male genital diseases, C5-convertase, medicine, Animals, Immunology and Allergy, Complement Activation, chemistry.chemical_classification, Innate immune system, Properdin, medicine.disease, Hemolysis, female genital diseases and pregnancy complications, Cell biology, Complement system, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Enzyme, chemistry, Alternative complement pathway, Rabbits

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba78de6d5f0327c34a72846b5da0371
https://doi.org/10.4049/jimmunol.2100238

المؤلفون: Sarah de Jong, Carel B. Hoyng, Lambert P J W van den Heuvel, Anita de Breuk, Elena B. Volokhina, Yara T. E. Lechanteur, Alejandro Garanto, Sascha Fauser, Suresh Katti, Bjorn Bakker, Anneke I. den Hollander

المصدر: Human Molecular Genetics, 31, 455-70
Human Molecular Genetics, 31, 3, pp. 455-70

مصطلحات موضوعية: Heterozygote, Mutation, Missense, Biology, Polymorphism, Single Nucleotide, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], Frameshift mutation, Macular Degeneration, Age related, Genetics, medicine, Missense mutation, Humans, In patient, Molecular Biology, Gene, Genetics (clinical), Aged, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], General Medicine, Complement System Proteins, Macular degeneration, medicine.disease, eye diseases, Complement system, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Factor H, Complement Factor H, Immunology, sense organs

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f32a9ecf69385e49c5e9c94afcf04f0
http://hdl.handle.net/2066/248812

المؤلفون: Sarah de Jong (11904641), Anita de Breuk (11904644), Bjorn Bakker (2578045), Suresh Katti (11904647), Carel B. Hoyng (11027972), Sara C. Nilsson (11904650), Anna M. Blom (53233), Lambert P. van den Heuvel (10731124), Anneke I. den Hollander (10195484), Elena B. Volokhina (6847514)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, complement factor I, genetic variants, age-related macular degeneration, atypical hemolytic uremic syndrome, functional analysis

Relation: https://figshare.com/articles/figure/Image_1_Functional_Analysis_of_Variants_in_Complement_Factor_I_Identified_in_Age-Related_Macular_Degeneration_and_Atypical_Hemolytic_Uremic_Syndrome_tif/17869598

الاتاحة: https://doi.org/10.3389/fimmu.2021.789897.s001

المؤلفون: Sarah de Jong (11904641), Anita de Breuk (11904644), Bjorn Bakker (2578045), Suresh Katti (11904647), Carel B. Hoyng (11027972), Sara C. Nilsson (11904650), Anna M. Blom (53233), Lambert P. van den Heuvel (10731124), Anneke I. den Hollander (10195484), Elena B. Volokhina (6847514)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, complement factor I, genetic variants, age-related macular degeneration, atypical hemolytic uremic syndrome, functional analysis

Relation: https://figshare.com/articles/dataset/Table_1_Functional_Analysis_of_Variants_in_Complement_Factor_I_Identified_in_Age-Related_Macular_Degeneration_and_Atypical_Hemolytic_Uremic_Syndrome_xlsx/17869619

الاتاحة: https://doi.org/10.3389/fimmu.2021.789897.s004

المؤلفون: Marloes A H M, Michels, Nicole C A J, van de Kar, Elena B, Volokhina, Bert L P W J, van den Heuvel

المصدر: Methods in molecular biology (Clifton, N.J.). 2227

مصطلحات موضوعية: Complement C3 Nephritic Factor, Glomerulonephritis, Complement Pathway, Alternative, Guinea Pigs, Animals, Humans, Complement C3, Complement C3-C5 Convertases, Rabbits, Complement Activation, Complement Hemolytic Activity Assay, Atypical Hemolytic Uremic Syndrome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c6f7f4bd420969a7298c810389c25f0a
https://pubmed.ncbi.nlm.nih.gov/33847933

المؤلفون: Maheswara R Duvvari, Codrut C Paun, Gabriëlle H S Buitendijk, Nicole T M Saksens, Elena B Volokhina, Tina Ristau, Frederieke E Schoenmaker-Koller, Johannes P H van de Ven, Joannes M M Groenewoud, Lambertus P W J van den Heuvel, Albert Hofman, Sascha Fauser, André G Uitterlinden, Caroline C W Klaver, Carel B Hoyng, Eiko K de Jong, Anneke I den Hollander

المصدر: PLoS ONE, Vol 9, Iss 4, p e94165 (2014)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3988049?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/195db82bfe884c57936a5cceeb697ab7

الاتاحة: https://doi.org/10.1371/journal.pone.0094165
https://doaj.org/article/195db82bfe884c57936a5cceeb697ab7

المؤلفون: Lambertus P. van den Heuvel, Jack F.M. Wetzels, Caroline Duineveld, Nicole C. A. J. van de Kar, Elena B. Volokhina, Mendy Ter Avest, Rob ter Heine, Romy N. Bouwmeester, Kioa L. Wijnsma

المصدر: Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology, 11
Frontiers in Immunology

مصطلحات موضوعية: 0301 basic medicine, lcsh:Immunologic diseases. Allergy, medicine.medical_specialty, therapeutic drug monitoring, Immunology, 030232 urology & nephrology, Case Report, Gastroenterology, 03 medical and health sciences, aHUS, 0302 clinical medicine, Pharmacotherapy, All institutes and research themes of the Radboud University Medical Center, Internal medicine, Atypical hemolytic uremic syndrome, medicine, Immunology and Allergy, pharmacokinetic, Proteinuria, medicine.diagnostic_test, business.industry, atypical hemolytic uremic syndrome, Eculizumab, medicine.disease, Regimen, 030104 developmental biology, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], Therapeutic drug monitoring, eculizumab, Age of onset, medicine.symptom, Renal disorders Radboud Institute for Health Sciences [Radboudumc 11], proteinuria, business, lcsh:RC581-607, Kidney disease, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18573eb3e2104198ce9c2f922660f28
https://www.frontiersin.org/articles/10.3389/fimmu.2020.612706/full

المؤلفون: Anita de Breuk, Sarah de Jong, Lambert P J W van den Heuvel, Yara T. E. Lechanteur, Anneke I. den Hollander, Giuliana Gagliardi, Suresh Katti, Alejandro Garanto, Elena B. Volokhina

المصدر: Progress in Retinal and Eye Research, 84

مصطلحات موضوعية: 0301 basic medicine, genetic structures, Disease, Bioinformatics, Systemic circulation, Sensory disorders Donders Center for Medical Neuroscience [Radboudumc 12], Macular Degeneration, 03 medical and health sciences, 0302 clinical medicine, Age related, Genetic variation, Humans, Medicine, Induced pluripotent stem cell, Complement Activation, Aged, business.industry, Genetic Variation, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Complement System Proteins, Macular degeneration, medicine.disease, Sensory Systems, eye diseases, Complement system, Clinical trial, Ophthalmology, 030104 developmental biology, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030221 ophthalmology & optometry, sense organs, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f9d6315a94c3fde9720e41de5bac6d

المؤلفون: Elena B. Volokhina, Marcin Okroj

المصدر: Frontiers in Immunology, 12
Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine.medical_treatment, Immunology, rituximab, medicine, antibodies, Immunology and Allergy, complement, biology, business.industry, Immunotherapy, Eculizumab, factor H, Virology, Complement (complexity), Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], biology.protein, eculizumab, Rituximab, immunotherapy, Antibody, lcsh:RC581-607, business, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86aa2c2c8a9d466598a075e413036e8
https://doi.org/10.3389/fimmu.2021.663459

المؤلفون: Bert van den Heuvel, Nicole C. A. J. van de Kar, Elena B. Volokhina, Marloes A. H. M. Michels

المصدر: Methods in Molecular Biology, pp. 83-96
MIMB ; 2227, 83-96. [S.l.] : Springer
STARTPAGE=83;ENDPAGE=96;TITLE=MIMB ; 2227
The Complement System ISBN: 9781071610152

مصطلحات موضوعية: 0301 basic medicine, Innate immune system, 030232 urology & nephrology, Autoantibody, Eculizumab, Biology, medicine.disease, MIMB, C3-convertase, Complement system, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Glomerulopathy, Atypical hemolytic uremic syndrome, Immunology, medicine, Alternative complement pathway, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1f4875adecd1cb7684f10421848ee4
https://repository.ubn.ru.nl/handle/2066/234028

المؤلفون: Elena B Volokhina, Jan Grijpstra, Frank Beckers, Erika Lindh, Viviane Robert, Jan Tommassen, Martine P Bos

المصدر: PLoS ONE, Vol 8, Iss 12, p e85799 (2013)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3869937?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/66e90b2e9f89457ebf57f7921dca3f54

الاتاحة: https://doi.org/10.1371/journal.pone.0085799
https://doaj.org/article/66e90b2e9f89457ebf57f7921dca3f54