نتائج البحث - "El Kerdawy, Ahmed M."

1

Academic Journal

Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents

المؤلفون: Abd El-Karim, Somaia S., Syam, Yasmin M., El Kerdawy, Ahmed M., Abdel-Mohsen, Heba T.

مصطلحات موضوعية: F150 Medicinal Chemistry, F151 Pharmaceutical Chemistry

وصف الملف: application/pdf

Relation: https://eprints.lincoln.ac.uk/id/eprint/56762/1/Quinazoline_manuscript_10_10_2023-AK-ref.pdf; Abd El-Karim, Somaia S., Syam, Yasmin M., El Kerdawy, Ahmed M. and Abdel-Mohsen, Heba T. (2024) Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents. Bioorganic Chemistry, 142 . p. 106920. ISSN 0045-2068

الاتاحة: https://eprints.lincoln.ac.uk/id/eprint/56762/
https://eprints.lincoln.ac.uk/id/eprint/56762/1/Quinazoline_manuscript_10_10_2023-AK-ref.pdf
https://doi.org/10.1016/j.bioorg.2023.106920

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2

Academic Journal

Discovery of dual rho-associated protein kinase 1 (ROCK1)/apoptosis signal–regulating kinase 1 (ASK1) inhibitors as a novel approach for non-alcoholic steatohepatitis (NASH) treatment

المؤلفون: Zaky, Yara A., Rashad, Mai W., Zaater, Marwa A., El Kerdawy, Ahmed M.

المساهمون: New Giza University

المصدر: BMC Chemistry ; volume 18, issue 1 ; ISSN 2661-801X

الاتاحة: http://dx.doi.org/10.1186/s13065-023-01081-3
https://link.springer.com/content/pdf/10.1186/s13065-023-01081-3.pdf
https://link.springer.com/article/10.1186/s13065-023-01081-3/fulltext.html

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3

Academic Journal

Furan- and Furopyrimidine-Based Derivatives: Synthesis, VEGFR‑2 Inhibition, and In Vitro Cytotoxicity.

المؤلفون: Abd El-Haleem, Akram H., Kassem, Manar Abd El-karim, Elnagar, Mohamed R., Abbas, Safinaz E-S., El Kerdawy, Ahmed M., Farouk, Ahmed K. B. A. W.

المصدر: ACS Medicinal Chemistry Letters; 12/12/2024, Vol. 15 Issue 21, p2150-2157, 8p

4

Academic Journal

Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents

المؤلفون: Ismail, Rania S. M., El Kerdawy, Ahmed M., Soliman, Dalia H., Georgey, Hanan H., Abdel Gawad, Nagwa M., Angeli, Andrea, Supuran, Claudiu T.

المساهمون: Egyptian Russian University

المصدر: BMC Chemistry ; volume 17, issue 1 ; ISSN 2661-801X

الاتاحة: http://dx.doi.org/10.1186/s13065-023-00994-3
https://link.springer.com/content/pdf/10.1186/s13065-023-00994-3.pdf
https://link.springer.com/article/10.1186/s13065-023-00994-3/fulltext.html

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5

Academic Journal

Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights.

المؤلفون: Eldehna, Wagdy M, Maklad, Raed M, Almahli, Hadia, Al-Warhi, Tarfah, Elkaeed, Eslam B, Abourehab, Mohammed AS, Abdel-Aziz, Hatem A, El Kerdawy, Ahmed M

المصدر: nlmid: 101150203 ; essn: 1475-6374

مصطلحات موضوعية: Kinase inhibitors, apoptotic agents, benzofuran synthesis, molecular docking, pancreatic cancer, Antineoplastic Agents, Benzofurans, Cell Line, Tumor, Cell Proliferation, Drug Screening Assays, Antitumor, Molecular Docking Simulation, Molecular Structure, Protein Kinase Inhibitors, Structure-Activity Relationship

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/337586

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/337586
https://doi.org/10.17863/CAM.84995

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6

Academic Journal

Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights

المؤلفون: Al-Warhi,Tarfah, El Kerdawy,Ahmed M, Said,Mohamed A, Albohy,Amgad, Elsayed,Zainab M, Aljaeed,Nada, Elkaeed,Eslam B, Eldehna,Wagdy M, Abdel-Aziz,Hatem A, Abdelmoaz,Miral A

مصطلحات موضوعية: Drug Design, Development and Therapy

وصف الملف: text/html

Relation: https://www.dovepress.com/novel-2-5-aryl-45-dihydropyrazol-1-ylthiazol-4-one-as-egfr-inhibitors--peer-reviewed-fulltext-article-DDDT

الاتاحة: https://www.dovepress.com/novel-2-5-aryl-45-dihydropyrazol-1-ylthiazol-4-one-as-egfr-inhibitors--peer-reviewed-fulltext-article-DDDT

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7

Academic Journal

QSRR modeling of the chromatographic retention behavior of some quinolone and sulfonamide antibacterial agents using firefly algorithm coupled to support vector machine

المؤلفون: Fouad, Marwa A., Serag, Ahmed, Tolba, Enas H., El-Shal, Manal A., El Kerdawy, Ahmed M.

المساهمون: Cairo University

المصدر: BMC Chemistry ; volume 16, issue 1 ; ISSN 2661-801X

الاتاحة: http://dx.doi.org/10.1186/s13065-022-00874-2
https://link.springer.com/content/pdf/10.1186/s13065-022-00874-2.pdf
https://link.springer.com/article/10.1186/s13065-022-00874-2/fulltext.html

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8

Academic Journal

Identification of 3-(piperazinylmethyl)benzofuran derivatives as novel type II CDK2 inhibitors: design, synthesis, biological evaluation, and in silico insights

المؤلفون: Eldehna, Wagdy M., Maklad, Raed M., Almahli, Hadia, Al-Warhi, Tarfah, Elkaeed, Eslam B., Abourehab, Mohammed A. S., Abdel-Aziz, Hatem A., El Kerdawy, Ahmed M.

المساهمون: The Deanship of Scientific Research at Princess Nourah Bint Abdulrahman University, Umm Al-Qura University

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry ; volume 37, issue 1, page 1227-1240 ; ISSN 1475-6366 1475-6374

الاتاحة: http://dx.doi.org/10.1080/14756366.2022.2062337
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2062337

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9

Academic Journal

Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights

المؤلفون: Al-Warhi, Tarfah, El Kerdawy, Ahmed M, Said, Mohamed A, Albohy, Amgad, Elsayed, Zainab M, Aljaeed, Nada, Elkaeed, Eslam B, Eldehna, Wagdy M, Abdel-Aziz, Hatem A, Abdelmoaz, Miral A

المصدر: Drug Design, Development and Therapy ; volume Volume 16, page 1457-1471 ; ISSN 1177-8881

الاتاحة: http://dx.doi.org/10.2147/dddt.s356988
https://www.dovepress.com/getfile.php?fileID=80799

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10

Academic Journal

Design, synthesis and anticancer activity of novel 2-arylbenzimidazole/2-thiopyrimidines and 2-thioquinazolin-4(3H)-ones conjugates as targeted RAF and VEGFR-2 kinases inhibitors

المؤلفون: Ali, Islam H., Abdel-Mohsen, Heba T., Mounier, Marwa M., Abo-elfadl, Mahmoud T., El Kerdawy, Ahmed M., Ghannam, Iman A.Y.

المصدر: Bioorganic Chemistry ; volume 126, page 105883 ; ISSN 0045-2068

الاتاحة: http://dx.doi.org/10.1016/j.bioorg.2022.105883
https://api.elsevier.com/content/article/PII:S0045206822002887?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0045206822002887?httpAccept=text/plain

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11

Academic Journal

Correlating physico-chemical properties of analytes with Hansen solubility parameters of solvents using machine learning algorithm for predicting suitable extraction solvent.

المؤلفون: Mostafa, Eman A., Azim, Mohammad Abdul, ElZaher, Asmaa A., ElKady, Ehab F., Fouad, Marwa A., Ghazy, Fatma H., Radi, Esraa A., El Makarim Saleh, Mahmoud Abo, El Kerdawy, Ahmed M.

المصدر: Scientific Reports; 8/13/2024, Vol. 14 Issue 1, p1-9, 9p

مصطلحات موضوعية: MACHINE learning, SOLVENT extraction, SUSTAINABLE chemistry, HUMAN information processing, SOLUBILITY, LIQUID-liquid extraction

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12

Academic Journal

Discovery of novel diaryl urea-oxindole hybrids as BRAF kinase inhibitors targeting BRAF and KRAS mutant cancers

المؤلفون: Ghannam, Iman A.Y., El Kerdawy, Ahmed M., Mounier, Marwa M., Abo-elfadl, Mahmoud T., Abdel-Mohsen, Heba T.

المساهمون: National Research Centre, National Cancer Institute

المصدر: Bioorganic Chemistry ; volume 153, page 107848 ; ISSN 0045-2068

الاتاحة: https://doi.org/10.1016/j.bioorg.2024.107848
https://api.elsevier.com/content/article/PII:S0045206824007533?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0045206824007533?httpAccept=text/plain

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13

Academic Journal

Design, synthesis, and in silico insights of novel N’-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors

المؤلفون: Eldehna, Wagdy M., Habib, Youmna A., Mahmoud, Abeer E., Barghash, Mohamed F., Elsayed, Zainab M., Elsawi, Ahmed E., Maklad, Raed M., Rashed, Mahmoud, Khalil, Amira, Hammad, Sherif F., Ali, Mamdouh M., El Kerdawy, Ahmed M.

المصدر: Bioorganic Chemistry ; volume 153, page 107829 ; ISSN 0045-2068

الاتاحة: https://doi.org/10.1016/j.bioorg.2024.107829
https://api.elsevier.com/content/article/PII:S004520682400734X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S004520682400734X?httpAccept=text/plain

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14

Academic Journal

Piperine solubility enhancement via DES formation: Elucidation of intermolecular interactions and impact of counterpart structure via computational and spectroscopic approaches

المؤلفون: Hassan, Sara A., Zaater, Marwa A., Abdel-Rahman, Islam M., Ibrahim, Elsayed A., El Kerdawy, Ahmed M., Abouelmagd, Sara A.

المصدر: International Journal of Pharmaceutics ; volume 667, page 124893 ; ISSN 0378-5173

الاتاحة: https://doi.org/10.1016/j.ijpharm.2024.124893
https://api.elsevier.com/content/article/PII:S037851732401127X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S037851732401127X?httpAccept=text/plain

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15

Academic Journal

In Silico and In Vitro Screening of Some Pregnane Glycosides Isolated from Certain Caralluma Species as SARS‐COV‐2 Main Protease Inhibitors

المؤلفون: Abdel‐Sattar, Essam, Kutkat, Omnia, El‐Shiekh, Riham A., El‐Ashrey, Mohamed K., El Kerdawy, Ahmed M.

المصدر: Chemistry & Biodiversity ; volume 21, issue 4 ; ISSN 1612-1872 1612-1880

الاتاحة: http://dx.doi.org/10.1002/cbdv.202301786
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202301786

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16

Academic Journal

Benzimidazole-oxindole hybrids as multi-kinase inhibitors targeting melanoma

المؤلفون: Allam, Rasha M., El Kerdawy, Ahmed M., Gouda, Ahmed E., Ahmed, Kawkab A., Abdel-Mohsen, Heba T.

المصدر: Bioorganic Chemistry ; volume 146, page 107243 ; ISSN 0045-2068

الاتاحة: http://dx.doi.org/10.1016/j.bioorg.2024.107243
https://api.elsevier.com/content/article/PII:S0045206824001482?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0045206824001482?httpAccept=text/plain

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17

Academic Journal

Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation

المؤلفون: Abdo Moustafa, Esraa, Abdelrasheed Allam, Heba, Fouad, Marwa A., El Kerdawy, Ahmed M., Nasser Eid El-Sayed, Nahed, Wagner, Christoph, Abdel-Aziz, Hatem A., Abdel Fattah Ezzat, Manal

المصدر: Bioorganic Chemistry ; volume 146, page 107324 ; ISSN 0045-2068

الاتاحة: http://dx.doi.org/10.1016/j.bioorg.2024.107324
https://api.elsevier.com/content/article/PII:S0045206824002293?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0045206824002293?httpAccept=text/plain

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18

Academic Journal

Novel thiazolidin-4-one benzenesulfonamide hybrids as PPARγ agonists: Design, synthesis and in vivo anti-diabetic evaluation

المؤلفون: Ali, Islam H., Hassan, Rasha M., El Kerdawy, Ahmed M., Abo-Elfadl, Mahmoud T., Abdallah, Heba M.I., Sciandra, Francesca, Ghannam, Iman A.Y.

المساهمون: Science and Technology Development Fund

المصدر: European Journal of Medicinal Chemistry ; volume 269, page 116279 ; ISSN 0223-5234

الاتاحة: http://dx.doi.org/10.1016/j.ejmech.2024.116279
https://api.elsevier.com/content/article/PII:S0223523424001594?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0223523424001594?httpAccept=text/plain

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19

Academic Journal

Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations

المؤلفون: El-Emam, Mohamed A., Sheta, Eman, El-Abhar, Hanan S., Abdallah, Dalaal M., El Kerdawy, Ahmed M., Eldehna, Wagdy M., Gowayed, Mennatallah A.

المصدر: Life Sciences ; volume 338, page 122362 ; ISSN 0024-3205

الاتاحة: http://dx.doi.org/10.1016/j.lfs.2023.122362
https://api.elsevier.com/content/article/PII:S0024320523009979?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0024320523009979?httpAccept=text/plain

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20

Academic Journal

Design and synthesis of novel quinazolinone‐based fibrates as PPARα agonists with antihyperlipidemic activity

المؤلفون: Hassan, Rasha M., Ali, Islam H., Abdel‐Maksoud, Mohammed S., Abdallah, Heba M. I., El Kerdawy, Ahmed M., Sciandra, Francesca, Ghannam, Iman A. Y.

المساهمون: Science and Technology Development Fund

المصدر: Archiv der Pharmazie ; volume 355, issue 3 ; ISSN 0365-6233 1521-4184

الاتاحة: https://doi.org/10.1002/ardp.202100399
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ardp.202100399
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ardp.202100399

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