المؤلفون: EIKI SHITARA, FUKIKO KOJIMA, TOMIO TAKEUCHI, YOSHIO NISHIMURA

المصدر: The Journal of Antibiotics. 1999, 52(3):348

المؤلفون: Takehiro Fukami, Yui Mazaki, Kenichi Washizuka, Hideaki Niwa, Takeshi Tsumura, Hiroo Koyama, Yuko Kano, Yasuko Koda, Fumiyuki Shirai, Kouichi Kitamura, Yoko Yashiroda, Anna Mizutani, Hitomi Yuki, Eiki Shitara, Hiroyuki Seimiya, Teruki Honma, Shin Sato, Tsubasa Chikada, Minoru Yoshida, Masayuki Okue, Takashi Watanabe, Takashi Umehara, Yukiko Muramatsu, Akiko Nagamori, Myung-Kyu Jang, Haruka Yoshida, Mikako Shirouzu

المصدر: Journal of medicinal chemistry. 63(8)

مصطلحات موضوعية: Colorectal cancer, Administration, Oral, Mice, SCID, 01 natural sciences, 03 medical and health sciences, Mice, Mice, Inbred NOD, Tankyrases, Cell Line, Tumor, Drug Discovery, AXIN2, medicine, Animals, Humans, Enzyme Inhibitors, Polymerase, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, Cell growth, Wnt signaling pathway, medicine.disease, Highly selective, Xenograft Model Antitumor Assays, 0104 chemical sciences, Protein Structure, Tertiary, Rats, 010404 medicinal & biomolecular chemistry, Enzyme, Treatment Outcome, Drug Design, Colonic Neoplasms, Cancer research, biology.protein, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30c01958ef416b8aff1cab18d74f999
https://pubmed.ncbi.nlm.nih.gov/32202790

المؤلفون: Yoshihiro Takayama, Eiki Shitara, Minoru Yonezawa, Toshie Sugano, Yukari Tanaka, Yoko Hirai, Keiko Yamada, Jun Nagura, Koji Kijima, Mizuyo Kurazono, Sho Takahata

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/49/8/3526.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.523.9445; http://aac.asm.org/content/49/8/3526.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.523.9445
http://aac.asm.org/content/49/8/3526.full.pdf

المؤلفون: Takahisa Maruyama, Eiki Shitara, Minoru Yonezawa, Mizuyo Kurazono, Takashi Ida, Keiko Yamada, Yoko Hirai

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/48/8/2831.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.609.480; http://aac.asm.org/content/48/8/2831.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.609.480
http://aac.asm.org/content/48/8/2831.full.pdf

المؤلفون: Eijiro Umemura, Yoshinari Wakiyama, Ko Kumura, Kazutaka Ueda, Hideki Fushimi, Takashi Watanabe, Keiichi Ajito, Eiki Shitara, Takuji Yoshida

المصدر: The Journal of Antibiotics. 69:440-445

مصطلحات موضوعية: 0301 basic medicine, Streptococcus pyogenes, Antiparasitic, medicine.drug_class, Stereochemistry, 030106 microbiology, Biology, medicine.disease_cause, 01 natural sciences, Beta-lactam, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Drug Discovery, Streptococcus pneumoniae, medicine, Pharmacology, 010405 organic chemistry, biochemical phenomena, metabolism, and nutrition, Combinatorial chemistry, Glycopeptide, Anti-Bacterial Agents, Lincomycin, 0104 chemical sciences, chemistry, Genes, Bacterial, Azetidines, Antibacterial activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d30e339fef0c158e12c0979528c074
https://doi.org/10.1038/ja.2015.134

المؤلفون: Tomoaki Miura, Kenichi Kanemoto, Hideki Fushimi, Keiichi Ajito, Takuji Yoshida, Eiki Shitara, Satomi Natsume

المصدر: Bioorganic & Medicinal Chemistry. 18:2735-2747

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Azalide, Gram-Positive Bacteria, Biochemistry, Bacterial protein, Bacterial Proteins, Drug Resistance, Bacterial, mental disorders, Drug Discovery, medicine, Molecular Biology, Aza Compounds, Chemistry, Organic Chemistry, Membrane Proteins, Anti-Bacterial Agents, Streptococcus pneumoniae, Molecular Medicine, Indicators and Reagents, Macrolides, Antibacterial activity, psychological phenomena and processes, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40701d9e952ff05593e530a223e48241
https://doi.org/10.1016/j.bmc.2010.02.017

المؤلفون: Takahisa Maruyama, Eiji Matsuhisa, Hiromi Meiji Seika Kaisha Ltd. Takata, Eiki Shitara, Katsuyoshi Iwamatsu, Yuko Kano, Toshihiko Takata, Yasuo Yamamoto, Mizuyo Kurazono, Kunio Atsumi

المصدر: Bioorganic & Medicinal Chemistry. 15:6379-6387

مصطلحات موضوعية: Staphylococcus aureus, Carbapenem, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Moiety, Thiazole, Molecular Biology, Antibacterial agent, Bicyclic molecule, Organic Chemistry, Imidazoles, Stereoisomerism, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Acute toxicity, Anti-Bacterial Agents, Kinetics, Thiazoles, Carbapenems, chemistry, Toxicity, Lactam, Molecular Medicine, Methicillin Resistance, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cce067b89fc783d0406088dd28b68de
https://doi.org/10.1016/j.bmc.2007.06.057

المؤلفون: Katsuyoshi Iwamatsu, Yasuo Yamamoto, Takahisa Maruyama, Kunio Atsumi, Eiki Shitara, Mizuyo Kurazono, Yuko Kano

المصدر: Bioorganic & Medicinal Chemistry. 15:392-402

مصطلحات موضوعية: Staphylococcus aureus, Carbapenem, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Pyridinium Compounds, Microbial Sensitivity Tests, medicine.disease_cause, Biochemistry, Microbiology, Haemophilus influenzae, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Streptococcus pneumoniae, medicine, Molecular Biology, biology, Organic Chemistry, Stereoisomerism, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, biology.organism_classification, Anti-Bacterial Agents, Carbapenems, chemistry, Molecular Medicine, Pyridinium, Antibacterial activity, Bacteria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41986aaa132f2be4097a5ea2a744dc15
https://doi.org/10.1016/j.bmc.2006.09.049

المؤلفون: Eiki Shitara, Minoru Yonezawa, Yoko Hirai, Takahisa Maruyama, Mizuyo Kurazono, Takashi Ida, Keiko Yamada

المصدر: Antimicrobial Agents and Chemotherapy. 48:2831-2837

مصطلحات موضوعية: Staphylococcus aureus, Carbapenem, Imipenem, medicine.drug_class, Gram-positive bacteria, Antibiotics, Electrophoretic Mobility Shift Assay, Microbial Sensitivity Tests, Muramoylpentapeptide Carboxypeptidase, Gram-Positive Bacteria, medicine.disease_cause, Microbiology, Bacterial Proteins, Gram-Negative Bacteria, Streptococcus pneumoniae, medicine, Penicillin-Binding Proteins, Pharmacology (medical), Antibacterial agent, Pharmacology, biology, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Infectious Diseases, Carbapenems, Hexosyltransferases, Susceptibility, Peptidyl Transferases, Methicillin Resistance, Carrier Proteins, Staphylococcus, Plasmids, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b62c29843e2495c62af4e6bbb22aaad
https://doi.org/10.1128/aac.48.8.2831-2837.2004

المؤلفون: Tomio Takeuchi, Eiki Shitara, Yasuaki Hiramoto, Yoshio Nishimura, Kuniaki Nerome

المصدر: Organic Letters. 2:3837-3840

مصطلحات موضوعية: Oseltamivir, Clostridium perfringens, Stereochemistry, medicine.drug_class, viruses, Neuraminidase, Antiviral Agents, Guanidines, Biochemistry, Streptomyces, Virus, chemistry.chemical_compound, Zanamivir, Piperidines, Acetamides, medicine, Enzyme Inhibitors, Physical and Theoretical Chemistry, Pyrans, biology, Neuraminidase inhibitor, Organic Chemistry, virus diseases, Orthomyxoviridae, biology.organism_classification, chemistry, Siastatin B, Sialic Acids, biology.protein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c60a40814e5205d02ba549dc7e807fd
https://doi.org/10.1021/ol000261d

المؤلفون: Yoshio Nishimura, Eiki Shitara, Fukiko Kojima, Tomio Takeuchi

المصدر: Bioorganic & Medicinal Chemistry. 8:343-352

مصطلحات موضوعية: Stereochemistry, Molecular Sequence Data, Clinical Biochemistry, Carbohydrates, Pharmaceutical Science, Diamines, Biochemistry, Chemical synthesis, Fucose, chemistry.chemical_compound, Diamine, Drug Discovery, Fucosidase, Enzyme Inhibitors, Molecular Biology, alpha-L-Fucosidase, chemistry.chemical_classification, Molecular Structure, biology, Spectrum Analysis, Organic Chemistry, Enzyme, Carbohydrate Sequence, chemistry, Enzyme inhibitor, biology.protein, Aminal, Molecular Medicine, Mitsunobu reaction, Imines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0c8a5ec10c97c18a389ef2857bebb6
https://doi.org/10.1016/s0968-0896(99)00289-8

المؤلفون: Fukiko Kojima, Tomio Takeuchi, Eiki Shitara, Yoshio Nishimura

المصدر: Bioorganic & Medicinal Chemistry. 7:1241-1246

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Streptomyces, Chemical synthesis, chemistry.chemical_compound, Piperidines, D-Glucose, Drug Discovery, Glycoside hydrolase, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, biology.organism_classification, Enzyme, Enzyme inhibitor, biology.protein, Molecular Medicine, Stereoselectivity, Aspergillus niger, Glucosidases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c95f10bfe8dbc3291ba3de60930458
https://doi.org/10.1016/s0968-0896(99)00048-6

المؤلفون: Eiki Shitara, Tomio Takeuchi, Yoshio Nishimura

المصدر: Tetrahedron Letters. 40:2351-2354

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Aminal, Enantioselective synthesis, Glycosidase inhibitor, α l fucosidase, Mitsunobu reaction, Ring (chemistry), Biochemistry, IC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::51ae6e7081b3706973278682c53715db
https://doi.org/10.1016/s0040-4039(99)00184-7

المؤلفون: Mizuyo Kurazono, Toshie Sugano, Yoko Hirai, Sho Takahata, Jun Nagura, Minoru Yonezawa, Eiki Shitara, Keiko Yamada, Yukari Tanaka, Koji Kijima, Yoshihiro Takayama

المصدر: Antimicrobial Agents and Chemotherapy. 49:3526-3528

مصطلحات موضوعية: Staphylococcus aureus, Carbapenem, Micrococcaceae, Colony Count, Microbial, Microbial Sensitivity Tests, medicine.disease_cause, Staphylococcal infections, Microbiology, Vancomycin, medicine, Animals, Humans, Endocarditis, Experimental Therapeutics, Pharmacology (medical), Pharmacology, biology, business.industry, Therapeutic effect, Endocarditis, Bacterial, Staphylococcal Infections, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, medicine.disease, biology.organism_classification, Methicillin-resistant Staphylococcus aureus, Anti-Bacterial Agents, Disease Models, Animal, Treatment Outcome, Infectious Diseases, Carbapenems, Female, Methicillin Resistance, Rabbits, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7157376a63291596adabab8044788bf3
https://doi.org/10.1128/aac.49.8.3526-3528.2005

المؤلفون: Kiyoaki Katano, Kazue Sasaki, Takashi Tsuruoka, Masaro Shimizu, Shokichi Ohuchi, Yasuko Isomura, Mami Kawaguchi, Eiki Shitara, Tomoaki Miura

المصدر: Bioorganic & Medicinal Chemistry Letters. 6:2601-2606

مصطلحات موضوعية: Chemistry, Gpiib iiia antagonist, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Biochemistry, Combinatorial chemistry, Drug Discovery, Molecular Medicine, Moiety, Molecular Biology, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0789bb53e6a25e5a5cc30cedaadec4ac
https://doi.org/10.1016/0960-894x(96)00476-3

المؤلفون: Hitoshi Kamada, Jiro Horiuchi, Nobuyuki Kibushi, Eiki Shitara, Tetsuzo Kato, Ryuji Niwa

المصدر: Chemical and Pharmaceutical Bulletin. 44:2314-2317

مصطلحات موضوعية: Primary (chemistry), Triazines, medicine.drug_class, Guinea Pigs, Hydrochloric acid, General Chemistry, General Medicine, Chemical synthesis, Stimulation, Chemical, In vitro, Bronchodilator Agents, Guinea pig, chemistry.chemical_compound, chemistry, Cyanamide, Bronchodilator, Drug Discovery, medicine, Animals, Organic chemistry, Cyanogen bromide, Cyanogen Bromide, Muscle Contraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8231f1eae22692cfb6f6247609fed927
https://doi.org/10.1248/cpb.44.2314

المؤلفون: Masaro Shimizu, Eiki Shitara, Mami Kawaguchi, Yasuko Isomura, Takashi Tsuruoka, Shokichi Ohuchi, Kiyoaki Katano, Kazue Sasaki, Tomoaki Miura

المصدر: ChemInform. 28

مصطلحات موضوعية: Chemistry, Gpiib iiia antagonist, Stereochemistry, Antagonist, Moiety, General Medicine, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3de191927527c1790def84203b11e6e0
https://doi.org/10.1002/chin.199714218

المؤلفون: Jiro Horiuchi, Ryuji Niwa, Nobuyuki Kibushi, Hitoshi Kamada, Tetsuzo Kato, Eiki Shitara

المصدر: ChemInform. 28

مصطلحات موضوعية: chemistry.chemical_compound, Primary (chemistry), Chemistry, medicine.drug_class, Bronchodilator, medicine, Hydrochloric acid, Cyanogen bromide, General Medicine, Medicinal chemistry, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0f9c888e4aad604c02287da32fdabff2
https://doi.org/10.1002/chin.199726192

المؤلفون: Tomio Takeuchi, Eiki Shitara, Fukiko Kojima, Yoshio Nishimura

المصدر: ChemInform. 30

مصطلحات موضوعية: chemistry.chemical_compound, Stereochemistry, Chemistry, Galactose, Diamine, Iminosugar, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2739cf987ccba337559069c7644ece70
https://doi.org/10.1002/chin.199933232

المؤلفون: Kunio Atsumi, Yuko Kano, Eiki Shitara, Katsuyoshi Iwamatsu, Mizuyo Kurazono, Takahisa Maruyama, Yasuo Yamamoto

المصدر: ChemInform. 40

مصطلحات موضوعية: Carbapenem, Chemistry, medicine.drug_class, Antibiotics, General Medicine, biochemical phenomena, metabolism, and nutrition, Anti mrsa, bacterial infections and mycoses, medicine.disease_cause, Combinatorial chemistry, chemistry.chemical_compound, Staphylococcus aureus, polycyclic compounds, medicine, Moiety, Thiazole, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c8166d03e1995826ed16ee1b60d87379
https://doi.org/10.1002/chin.200921197