يعرض 1 - 20 نتائج من 63 نتيجة بحث عن '"Edward K Lobenhofer"', وقت الاستعلام: 0.54s تنقيح النتائج
  1. 1
    Academic Journal
    Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity.

    المؤلفون: Andrey Alexeyenko, Deena M Wassenberg, Edward K Lobenhofer, Jerry Yen, Elwood Linney, Erik L L Sonnhammer, Joel N Meyer

    المصدر: PLoS ONE, Vol 5, Iss 5, p e10465 (2010)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: http://europepmc.org/articles/PMC2864754?pdf=render; https://doaj.org/toc/1932-6203

    URL الوصول: https://doaj.org/article/0bc1e0db326041e7a50bbe15e2c51614

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  2. 2
    Academic Journal
    MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities

    المؤلفون: Marc A. Lafleur, Jonathan Werner, Madeline Fort, Edward K. Lobenhofer, Mercedesz Balazs, Ana Goyos

    المصدر: Journal of Immunotoxicology, Vol 17, Iss 1, Pp 110-121 (2020)

    مصطلحات موضوعية: mast cell degranulation, anaphylactoid, mrgprx2, in vitro, peptide, preclinical safety, Immunologic diseases. Allergy, RC581-607, Toxicology. Poisons, RA1190-1270

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/1547-691X; https://doaj.org/toc/1547-6901

    URL الوصول: https://doaj.org/article/e894f9a9b3264041a061465abb107886

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  3. 3
    Supplementary File from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca9c036ff650d951e09a23fd9df037d
    https://doi.org/10.1158/1078-0432.22478721.v1

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  4. 4
    Supplementary Methods from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ab61e9ac692d080514ff0ca474deda
    https://doi.org/10.1158/1078-0432.22478718

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  5. 5
    Supplementary Figure 3 from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b39bba8197b74f330bb0bf96836ca10
    https://doi.org/10.1158/1078-0432.22478733

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  6. 6
    Supplementary Figure 6 from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fabaa475fbbbc60934a70c1f6051cd7
    https://doi.org/10.1158/1078-0432.22478724.v1

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  7. 7
    Data from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dea7869f950cb3f6173b8394654616e
    https://doi.org/10.1158/1078-0432.c.6530028.v1

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  8. 8
    Supplementary Tables from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1913d46e2c693c8eafdefa39fa3c8b0a
    https://doi.org/10.1158/1078-0432.22478715

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  9. 9
    Supplementary Figure 1 from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00314926974585c9c925bea1763e6742
    https://doi.org/10.1158/1078-0432.22478739

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  10. 10
    Supplementary Figure 2 from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461100ad3b39468bf2aae35f513e8116
    https://doi.org/10.1158/1078-0432.22478736.v1

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  11. 11
    Supplementary Figure 5 from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bba8ad34ad4b6cc378b872e3503982d
    https://doi.org/10.1158/1078-0432.22478727.v1

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  12. 12
    Supplementary Figure 4 from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Paul E. Hughes, Julie M. Bailis, Angela Coxon, Jude Canon, Pedro J. Beltran, Jennitte Stevens, Sean Caenepeel, Yajing Yang, Tobias Raum, Joshua T. Pearson, Matthias Friedrich, Oliver Homann, Fei Lee, Siyuan Liu, Jonathan Werner, Christopher M. Murawsky, Melissa Thomas, Petra Deegen, Jinghui Zhan, Juan Estrada, Edward K. Lobenhofer, Keegan Cooke, Michael J. Giffin

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef46e1f852430eb7a99e61c73e5e980
    https://doi.org/10.1158/1078-0432.22478730.v1

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  13. 13
    AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

    المؤلفون: Jinghui Zhan, Christopher Murawsky, Petra Deegen, Jonathan Werner, Oliver Homann, Siyuan Liu, Melissa Thomas, Angela Coxon, Keegan Cooke, Pedro J. Beltran, Joshua T. Pearson, Juan Estrada, Fei Lee, Tobias Raum, Julie M. Bailis, Matthias Friedrich, Jude Canon, Jennitte Stevens, Giffin Michael John, Sean Caenepeel, Yajing Yang, Paul E. Hughes, Edward K. Lobenhofer

    المصدر: Clinical Cancer Research. 27:1526-1537

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, T-Lymphocytes, T cell, Antineoplastic Agents, Apoptosis, Mice, SCID, Mice, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Antibodies, Bispecific, Tumor Cells, Cultured, Animals, Humans, Medicine, Potency, Lung cancer, Cell Proliferation, business.industry, Intracellular Signaling Peptides and Proteins, Antibodies, Monoclonal, Membrane Proteins, Half-life, medicine.disease, Small Cell Lung Carcinoma, Xenograft Model Antitumor Assays, respiratory tract diseases, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, Tolerability, Cell culture, 030220 oncology & carcinogenesis, Pharmacodynamics, Cancer research, Female, Non small cell, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcaceaaf177b717f0e24403146de6ad
    https://doi.org/10.1158/1078-0432.ccr-20-2845

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  14. 14
    Academic Journal
    Transcriptional effects of transfection: the potential for misinterpretation of gene expression data generated from transiently transfected cells

    المؤلفون: Linda B. Jacobsen, Susan A. Calvin, Edward K. Lobenhofer

    المصدر: BioTechniques, Vol 47, Iss 1, Pp 617-624 (2009)

    مصطلحات موضوعية: transfection, microarray, off-target effects, gene expression profiling, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

    URL الوصول: https://doaj.org/article/ed5abc6f61f842baafe909e331b2a4f5

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  15. 15
    MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities

    المؤلفون: Jonathan Werner, Edward K. Lobenhofer, Mercedesz Balazs, Madeline M. Fort, Ana Goyos, Marc A. Lafleur

    المصدر: Journal of Immunotoxicology, Vol 17, Iss 1, Pp 110-121 (2020)

    مصطلحات موضوعية: Receptors, Neuropeptide, Cell, Drug Evaluation, Preclinical, Antigens, CD34, Peptide, 010501 environmental sciences, Toxicology, Immunoglobulin E, 01 natural sciences, Cell Degranulation, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Mast Cells, Receptor, Cell Engineering, in vitro, Cells, Cultured, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, Degranulation, preclinical safety, Hematopoietic Stem Cell Mobilization, mast cell degranulation, peptide, Cell biology, medicine.anatomical_structure, Histamine, lcsh:Immunologic diseases. Allergy, Primary Cell Culture, Immunology, Nerve Tissue Proteins, Sensitivity and Specificity, 03 medical and health sciences, Antigen, lcsh:RA1190-1270, medicine, Humans, lcsh:Toxicology. Poisons, 030304 developmental biology, 0105 earth and related environmental sciences, anaphylactoid, Cytotoxicity Tests, Immunologic, Hematopoietic Stem Cells, In vitro, High-Throughput Screening Assays, mrgprx2, biology.protein, Peptides, lcsh:RC581-607

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3dd30df11ea8c947688df364414984
    https://doi.org/10.1080/1547691x.2020.1757793

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  16. 16
    Academic Journal
    2008 Lobenhofer et Volume al. 9, Issue 6, Article R100 Open Access Method

    المؤلفون: Edward K Lobenhofer, J Todd Auman, Pamela E Blackshear, Gary A Boorman, Pierre R Bushel, Michael L Cunningham, Jennifer M Fostel, Kevin Gerrish, Ra N Heinloth, Richard D Irwin, David E Malarkey, B Alex Merrick, Stella O Sieber, Charles J Tucker, Ra M Ward, Ralph E Wilson, Patrick Hurban, Raymond W Tennant, Richard S Paules

    المساهمون: The Pennsylvania State University CiteSeerX Archives

    المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/cb/9d/Genome_Biol_2008_Jun_20_9(6)_R100.tar.gz

    وصف الملف: application/zip

    Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.8925

    الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.274.8925

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  17. 17
    Academic Journal
    Notes

    المؤلفون: Patrick Hurban, Yael Karov, Edward K. Lobenhofer, Eilon Sharon, Yoel M. Shiboleth, Marat Shtutman, Omer Barad, Eti Meiri, Amir Avniel, Ranit Aharonov, Adi Barzilai, Isaac Bentwich, Uri Einav, Shlomit Gilad

    المساهمون: The Pennsylvania State University CiteSeerX Archives

    المصدر: https://www.cogenics.com/mediainfo/pdf/Pub_MicroRNA_expression.pdf.

    وصف الملف: application/pdf

    Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.511.798

    الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.511.798

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  18. 18
    Academic Journal
    Cells Prevents Estrogen-induced Mitogenesis 1

    المؤلفون: Edward K. Lobenhofer, Gudrun Huper, J. Dirk Iglehart, Jeffrey R. Marks

    المساهمون: The Pennsylvania State University CiteSeerX Archives

    المصدر: http://cgd.aacrjournals.org/cgi/reprint/11/2/99.pdf.

    وصف الملف: application/pdf

    Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.5414; http://cgd.aacrjournals.org/cgi/reprint/11/2/99.pdf

    الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.5414
    http://cgd.aacrjournals.org/cgi/reprint/11/2/99.pdf

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  19. 19
    P1.12-18 Nonclinical Safety Assessment of AMG 757, a DLL3 Bispecific T Cell Engager, in the Cynomolgus Monkey

    المؤلفون: Rhian Davies, M. Engwall, Jonathan Werner, Marc A. Lafleur, M. Giffin, Oliver Homann, G. Moffat, Edward K. Lobenhofer

    المصدر: Journal of Thoracic Oncology. 14:S541

    مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.anatomical_structure, Oncology, business.industry, T cell, Medicine, Nonclinical safety, Pharmacology, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23f704124a38b20fd1ea672877f44288
    https://doi.org/10.1016/j.jtho.2019.08.1131

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  20. 20
    P3.12-03 Targeting DLL3 with AMG 757, a BiTE® Antibody Construct, and AMG 119, a CAR-T, for the Treatment of SCLC

    المؤلفون: M. Giffin, Angela Coxon, Keegan Cooke, Matthias Friedrich, Tobias Raum, Edward K. Lobenhofer

    المصدر: Journal of Thoracic Oncology. 13:S971

    مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, biology, business.industry, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Medicine, Antibody, Car t cells, business, Construct (philosophy)

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0e57a0a70522c454b09f7afcaa5107fa
    https://doi.org/10.1016/j.jtho.2018.08.1826

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