المؤلفون: Radoslaw Wesolowski, Dirk Pleimes, Edgar Specker, Michael Bader

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 10 (2024)

مصطلحات موضوعية: pulmonary arterial hypertension, serotonin, TPH inhibitor, tryptophan hydroxylase, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9980

URL الوصول: https://doaj.org/article/7830e7f42de24ff5a8e532cc41eaec5f

المؤلفون: Saif Mohd, Andreas Oder, Edgar Specker, Martin Neuenschwander, Jens Peter Von Kries, Oliver Daumke

المصدر: PLoS ONE, Vol 19, Iss 7, p e0302704 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/bc1fb18899bc4379a14d127bddc963a0

المؤلفون: Philipp Jordan, Amanda Costa, Edgar Specker, Oliver Popp, Andrea Volkamer, Regina Piske, Tessa Obrusnik, Sabrina Kleissle, Kevin Stuke, Andre Rex, Martin Neuenschwander, Jens Peter von Kries, Marc Nazare, Phillip Mertins, Helmut Kettenmann, Susanne A Wolf

المصدر: PLoS ONE, Vol 18, Iss 2, p e0278325 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/4b3dd979f1fc499981cfbac16e8fa21b

المؤلفون: Hanna Bonnekoh, Carolina Vera, Angela Abad‐Perez, Silke Radetzki, Martin Neuenschwander, Edgar Specker, Niklas Amadeus Mahnke, Stefan Frischbutter, Eicke Latz, Marc Nazaré, Jens v. Kries, Marcus Maurer, Jörg Scheffel, Karoline Krause

المصدر: Clinical and Translational Allergy, Vol 11, Iss 5, Pp n/a-n/a (2021)

مصطلحات موضوعية: autoinflammation, contact dermatitis, disulfiram, inflammasome, interleukin‐18, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-7022

URL الوصول: https://doaj.org/article/471c47aa46c6442598d54381170bf9f1

المؤلفون: Ioanna Plastira, Lisha Joshi, Eva Bernhart, Jens Schoene, Edgar Specker, Marc Nazare, Wolfgang Sattler

المصدر: Frontiers in Cellular Neuroscience, Vol 13 (2019)

مصطلحات موضوعية: LPA5, microglia, chemokines, cytokines, neurotoxicity, transcription factors, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fncel.2019.00531/full; https://doaj.org/toc/1662-5102

URL الوصول: https://doaj.org/article/262fcef8f0914925bfe4f25da146b929

المؤلفون: Wolfgang Klein, Claudia Rutz, Jamina Eckhard, Becky Provinciael, Edgar Specker, Martin Neuenschwander, Gunnar Kleinau, Patrick Scheerer, Jens-Peter von Kries, Marc Nazaré, Kurt Vermeire, Ralf Schülein

المصدر: PLoS ONE, Vol 13, Iss 12, p e0208641 (2018)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e976463e5a704c7389c9d62dead9c3a8

المؤلفون: Manisha Juneja, Dennis Kobelt, Wolfgang Walther, Cynthia Voss, Janice Smith, Edgar Specker, Martin Neuenschwander, Björn-Oliver Gohlke, Mathias Dahlmann, Silke Radetzki, Robert Preissner, Jens Peter von Kries, Peter Michael Schlag, Ulrike Stein

المصدر: PLoS Biology, Vol 15, Iss 6, p e2000784 (2017)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5453412?pdf=render; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

URL الوصول: https://doaj.org/article/2c75230d61f7421f96fd23d8f6a02fd0

المؤلفون: Shixian Yan, Paul Curtis Schöpe, Joe Lewis, Kerstin Putzker, Ulrike Uhrig, Edgar Specker, Jens Peter von Kries, Peter Lindemann, Anahid Omran, Hector E. Sanchez-Ibarra, Anke Unger, Mia-Lisa Zischinsky, Bert Klebl, Wolfgang Walther, Marc Nazaré, Dennis Kobelt, Ulrike Stein

المصدر: Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115698- (2023)

مصطلحات موضوعية: High-throughput screening, Cancer metastasis, MACC1, Transcriptional inhibitors, Tetrazolo-pyridazine, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332223014968; https://doaj.org/toc/0753-3322; https://doaj.org/article/6858c7b995054e39a758cb5c3e16c24a

الاتاحة: https://doi.org/10.1016/j.biopha.2023.115698
https://doaj.org/article/6858c7b995054e39a758cb5c3e16c24a

المؤلفون: David M. Carter (11474174), Edgar Specker (2140024), Piotr H. Małecki (11474177), Jessica Przygodda (11474180), Krystyna Dudaniec (11474183), Manfred S. Weiss (1353906), Udo Heinemann (29836), Marc Nazaré (2030308), Ulrich Gohlke (2623651)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, proceeding via competition, low micromolar concentrations, containing lysine demethylase, benzimidazole pyrazole molecule, pca cells treated, kills pca cells, inhibited kdm4 isoforms, cytostatic properties arise, direct intracellular inhibition, 2 +, binding site analysis, pca ), site fe, properties tractable, enhanced properties, distal site, substituted variant, ray crystallography, provide evidence, prostate cancer

Relation: https://figshare.com/articles/journal_contribution/Enhanced_Properties_of_a_Benzimidazole_Benzylpyrazole_Lysine_Demethylase_Inhibitor_Mechanism-of-Action_Binding_Site_Analysis_and_Activity_in_Cellular_Models_of_Prostate_Cancer/16674389

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00693.s001

المؤلفون: María Isabel Fernández-Bachiller, Songhwan Hwang, María Elena Schembri, Peter Lindemann, Mónica Guberman, Svenja Herziger, Edgar Specker, Hans Matter, David W. Will, Jörg Czech, Michael Wagner, Armin Bauer, Herman Schreuder, Kurt Ritter, Matthias Urmann, Volkmar Wehner, Han Sun, Marc Nazaré

المصدر: Journal of Medicinal Chemistry. 65:13013-13028

مصطلحات موضوعية: Halogens, Indoles, Alkynes, Factor Xa, Drug Discovery, Proteins, Thermodynamics, Molecular Medicine, Molecular Dynamics Simulation, Ligands, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8a1e421784852173ad676bcf5b0524
https://doi.org/10.1021/acs.jmedchem.2c00865

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85960d2ef927f95bc58d9050e14e33dc
https://doi.org/10.1158/0008-5472.c.6507777.v1

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1c3b8e042c56d344ca8b88eb1b2c00
https://doi.org/10.1158/0008-5472.22409433.v1

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea1d1468d1f928152324a4cf1eef540
https://doi.org/10.1158/0008-5472.22409424.v1

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60c4e88d22887225bb6fd32f1dceb19
https://doi.org/10.1158/0008-5472.22409445.v1

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe4ac8fe2a884b7db5bad0791413fc8
https://doi.org/10.1158/0008-5472.22409427

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07481ea5080e1f98a0791a46b375ae28
https://doi.org/10.1158/0008-5472.22409418

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f6371b0e206eb48d573468e22de9e0
https://doi.org/10.1158/0008-5472.22409430.v1

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3c9e05c02ee16ba541ee1d21de52a7
https://doi.org/10.1158/0008-5472.22409436.v1

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cee6b57e4cdff03f0bbe6133b647c3
https://doi.org/10.1158/0008-5472.22409439

المؤلفون: Walter Birchmeier, Jens P. von Kries, William I. Weis, Annika Wulf-Goldenberg, Edgar Specker, Martin Neuenschwander, Qionghua Zhu, Liang Fang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94effdd1aa5c5a2ef8f66a9da06c0020
https://doi.org/10.1158/0008-5472.22409421.v1