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المؤلفون: Akira Yamauchi, Masahiro Yamamura, Keisuke Hino, Kyo Sasaki, Yuichi Hara, Fukuda Kotaro, Sohji Nishina, Kensuke Egashira
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 739-762 (2021)مصطلحات موضوعية: Male, 0301 basic medicine, Chemokine, Glucose uptake, Cell Culture Techniques, PLGA, poly(lactic-co-glycolic acid), 2-NDBG, 2-(N-[nitrobenz-2-oxa1,3-diazol-4-yl]amino)-2-deoxyglucose, CD8-Positive T-Lymphocytes, TNF-α, tumor necrosis factor-α, 2DG, 2-Deoxy-D-glucose, Mice, chemistry.chemical_compound, Liver Neoplasms, Experimental, 0302 clinical medicine, Polylactic Acid-Polyglycolic Acid Copolymer, Antineoplastic Combined Chemotherapy Protocols, Warburg Effect, Oncologic, GSH, glutathione, Cytotoxic T cell, IFN-γ, interferon-γ, Cytotoxicity, Immune Checkpoint Inhibitors, IFN-γ, Original Research, biology, Chemistry, Programmed Death 1, Liver Neoplasms, EZH2, enhancer of zeste homologue 2, Gastroenterology, PLGA, Drug Synergism, CCL, C-C motif chemokine, mRNA, messenger RNA, 030211 gastroenterology & hepatology, FITC, fluorescein isothiocyanate, JAK, Janus kinase, Carcinoma, Hepatocellular, ATP, adenosine triphosphate, CCR, C-C chemokine receptor type 4, ICG, indocyanine green, Treg, regulatory T cell, mTOR, mammalian target of rapamycin, macromolecular substances, Deoxyglucose, H3K27me3, H3 lysine 27 trimethylation, STAM, stelic animal model, STAT, signal transducers and activator of transcription, ER, endoplasmic reticulum, Interferon-gamma, homologue, 2, 03 medical and health sciences, ROS, reactive oxygen species, FBS, fetal bovine serum, Cell Line, Tumor, Animals, Humans, CXCL10, lcsh:RC799-869, PD1, programmed death 1, 18F-FDG, 18F-2-fluoro-2-deoxyglucose, Hepatology, technology, industry, and agriculture, Xenograft Model Antitumor Assays, Coculture Techniques, AMPK, AMP-activated protein kinase, PD-L1, programmed death-ligand 1, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer cell, Cancer research, biology.protein, Lactate, lcsh:Diseases of the digestive system. Gastroenterology, Tumor Escape, NP, nanoparticles, Nanoparticle Drug Delivery System, HCC, hepatocellular carcinoma, 2-Deoxy-D-glucose, CD8, DAPI, 4′,6-diamidino-2-phenylindole, DEN, diethylnitrosamine
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المؤلفون: Angela Mathison, Usman Yaqoob, Juan Pablo Arab, Vikas K. Verma, Vijay H. Shah, Philippe Mathurin, Gwen Lomberk, Sheng Cao, Rosa Martin-Mateos, Robert C. Huebert, Raul Urrutia, Thomas Greuter, Thiago M. De Assuncao, Nidhi Jalan-Sakrikar
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 197-209 (2019)مصطلحات موضوعية: WT, wild type, Liver Cirrhosis, 0301 basic medicine, IP, intraperitoneally, Small interfering RNA, PDGF, platelet-derived growth factor, Epigenesis, Genetic, PCR, polymerase chain reaction, 0302 clinical medicine, PDGF Signaling Pathway, Transforming Growth Factor beta, Carbon Tetrachloride, Original Research, Platelet-Derived Growth Factor, TGF-β, transforming growth factor β, Extracellular Matrix Proteins, biology, Chemistry, EZH2, enhancer of zeste homologue 2, EZH2, Gastroenterology, HSC, hepatic stellate cell, mRNA, messenger RNA, Up-Regulation, ECM, extracellular matrix, 3. Good health, Cell biology, ChIP, chromatin immunoprecipitation, H3K27me3, trimethylation of histone 3 at lysine 27, Histone methyltransferase, Liver Fibrosis, Epigenetics, 030211 gastroenterology & hepatology, Platelet-derived growth factor receptor, DKK1, Dickkopf-1, FDR, false discovery rate, CCL4, carbon tetrachloride, BDL, bile duct ligation, CTGF, connective tissue growth factor, α-SMA, α-smooth muscle actin, 03 medical and health sciences, VEGFA, vascular endothelial growth factor A, FBS, fetal bovine serum, Hepatic Stellate Cells, Animals, Humans, Enhancer of Zeste Homolog 2 Protein, lcsh:RC799-869, Ligation, IPA, Ingenuity Pathway Analysis, Messenger RNA, Hepatology, Histone Modifications, logFC, logarithmic fold change, Hepatic stellate cell activation, Mice, Inbred C57BL, 030104 developmental biology, siRNA, small interfering RNA, Hepatic stellate cell, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, Bile Ducts, HMT, histone methyltransferase, HCC, hepatocellular carcinoma
وصف الملف: application/pdf
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3Academic Journal
المساهمون: Hyunjoo Lee, Sun Och Yoon, Woon Yong Jeong, Han Kyeom Kim, Aeree Kim, Baek-hui Kim, Yoon, Sun Och
مصطلحات موضوعية: Adult, Aged, 80 and over, Biomarkers, Tumor/analysis, DNA (Cytosine-5-)-Methyltransferases/analysis, DNA (Cytosine-5-)-Methyltransferases/biosynthesis, Enhancer of Zeste Homolog 2 Protein, Female, Humans, Immunohistochemistry, Kaplan-Meier Estimate, Male, Middle Aged, Neoplasm Grading, Neoplasm Staging, Polycomb Repressive Complex 2/analysis, Polycomb Repressive Complex 2/biosynthesis, Polycomb-Group Proteins/analysis, Polycomb-Group Proteins/biosynthesis, Proportional Hazards Models, Stomach Neoplasms/metabolism, Stomach Neoplasms/mortality, Stomach Neoplasms/pathology, Tissue Array Analysis, Polycomb group proteins, EZH2 (enhancer of zeste homologue 2), Gastric cancer, Prognosis, BMI-1 (B lymphoma Mo-MLV insertion region 1 homolog)
Relation: HUMAN PATHOLOGY; J01011; OAK-2012-02683; https://ir.ymlib.yonsei.ac.kr/handle/22282913/90377; http://www.sciencedirect.com/science/article/pii/S0046817711005284; T201205194; HUMAN PATHOLOGY, Vol.43(10) : 1704-1710, 2012
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المؤلفون: Bruce C. Kone, Zhi Yuan Yu, Qun Kong
المصدر: Bioscience Reports
مصطلحات موضوعية: Af9, ALL1-fused gene from chromosome 9 protein, Transcription, Genetic, CD, collecting duct, SEC, super elongation complex, ECL, enhanced chemiluminescence, Biochemistry, H3K27me3, trimethylated histone H3 lysine 27, Mice, Transcription (biology), Protein Interaction Mapping, GST, glutathione transferase, Per1, Period 1, Promoter Regions, Genetic, Aldosterone, Polycomb Repressive Complex 1, Regulation of gene expression, 0303 health sciences, biology, ENaC, epithelial sodium channel, EZH2, enhancer of zeste homologue 2, 030302 biochemistry & molecular biology, Nuclear Proteins, HRP, horseradish peroxidase, qRT-PCR, quantitative real-time PCR, EGFP, enhanced green fluorescent protein, Chromatin, ChIP, chromatin immunoprecipitation, Protein Transport, CNT, connecting tubule, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, H3K79me3, histone H3 lysine 79 trimethylated, PRC, Polycomb repressive complex, PRC2, Protein Binding, Dot1a, disruptor of telomeric silencing isoform 1a, Ubiquitin-Protein Ligases, H2AK119, Biophysics, S2, Cell Line, 03 medical and health sciences, Histone H3, FBS, fetal bovine serum, Rnf, RING finger protein, CBX8, chromobox protein 8, Histone H2A, Animals, Kidney Tubules, Collecting, Epithelial Sodium Channels, Molecular Biology, Transcription factor, 030304 developmental biology, Original Paper, H3K27, QPCR, quantitative PCR, epigenetics, GRE, glucocorticoid responsive element, Cell Biology, MR, mineralocorticoid receptor, Molecular biology, Polycomb, Gene Expression Regulation, PcG, Polycomb group, siRNA, small interfering RNA, PH, polyhomeotic, biology.protein, methyltransferase, AFF1, AF4/FMR2 family member 1, Chromatin immunoprecipitation, DAPI, 4′,6-diamidino-2-phenylindole, H2AK119ub1, histone H2A lysine 119 monoubiquitination
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المصدر: Bioscience Reports, Vol 33, Iss 4, p e00061 (2013)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Bioscience Reportsمصطلحات موضوعية: MLL, mixed-lineage leukaemia, HDM, histone demethylase, lcsh:Life, lcsh:QR1-502, Gene Expression, SMARCA2, SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, type 2 (also known as BRM), HDAC, histone deacetylase, LSD1, lysine (K)-specific demethylase 1A, Review Article, medicine.disease_cause, Biochemistry, lcsh:Microbiology, Epigenesis, Genetic, Histones, CpG, cytosine phosphodiester bond guanine, lncRNA, long non-coding RNA, HOX, homeobox, long non-coding RNAs, Neoplasms, CTBP1-AS, C-terminal binding protein 1 antisense, PSF, phosphotyrosine-binding-associated splicing factor, Cancer epigenetics, CHD, chromodomain helicase DNA-binding protein, H3K27me3, histone 3 lysine 27 trymethylated, INK4b, inhibitor of cyclin-dependent kinase 4b, ARF, ADP-ribosylation factor, ANRASSF1, antisense non-coding RNA in the RASSF1A locus, Epigenesis, Regulation of gene expression, Genetics, EZH2, enhancer of zeste homologue 2, intergenic lncRNA, lincRNA, long intergenic non-coding RNA, ANRIL, antisense non-coding RNA in the INK4 locus, Nucleosomes, Gene Expression Regulation, Neoplastic, CRC, colorectal cancer, DNA methylation, RNA, Long Noncoding, S1, PCAT-1, prostate cancer-associated ncRNA transcript 1, Biophysics, Biology, regulatory RNA, RNA-guided gene silencing, INK4a, inhibitor of cyclin-dependent kinase 4a, XCI, X chromosome inactivation, medicine, Animals, Humans, Epigenetics, LICR, Ludwig Institute for Cancer Research, Molecular Biology, Gene, RNAPII, RNA polymerase II, Cancer, RASSF1A, Ras association (RalGDS/AF-6) domain family member 1 isoform A, Cell Biology, DNA Methylation, medicine.disease, cancer epigenetics, lcsh:QH501-531, XIST, X-inactive specific transcript, RNA, AR, androgen receptor, PRC, polycomb repressive complex, HMT, histone methyltransferase, HOTAIR, homeobox antisense intergenic RNA, Carcinogenesis, intronic lncRNA, Protein Processing, Post-Translational