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1Conference
المؤلفون: Christopher T. Rhodes, Dhanya Asokumar, Mira Sohn, Shovan Naskar, Lielle Elisha, Parker Stevenson, Dongjin R. Lee, Yajun Zhang, Pedro P. Rocha, Ryan K. Dale, Soohyun Lee, Timothy J. Petros
مصطلحات موضوعية: Cell Biology, Neuroscience, Cellular Nervous System, Central Nervous System, Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), Protein Trafficking, interneurons, medial ganglionic eminence (MGE), EZH2 (enhancer of zeste homolog 2), epigenetics, neurodevelopment, single cell sequencing, Cut&Tag, histone methylation
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2Academic Journal
المؤلفون: Christopher T. Rhodes, Dhanya Asokumar, Mira Sohn, Shovan Naskar, Lielle Elisha, Parker Stevenson, Dongjin R. Lee, Yajun Zhang, Pedro P. Rocha, Ryan K. Dale, Soohyun Lee, Timothy J. Petros
المصدر: Frontiers in Cellular Neuroscience, Vol 18 (2024)
مصطلحات موضوعية: interneurons, medial ganglionic eminence (MGE), EZH2 (enhancer of zeste homolog 2), epigenetics, neurodevelopment, single cell sequencing, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Minggang Fang, Sara K. Deibler, Pranathi Meda Krishnamurthy, Feng Wang, Paola Rodriguez, Shahid Banday, Ching-Man Virbasius, Miguel Sena-Esteves, Jonathan K. Watts, Michael R. Green
المصدر: Frontiers in Neuroscience, Vol 18 (2024)
مصطلحات موضوعية: FXS, FMR1 silencing, FMR1 reactivation, EZH2 (enhancer of zeste homolog 2), ASO - antisense oligonucleotides, neuron differentiation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: Serena Buontempo, Pasquale Laise, James M. Hughes, Sebastiano Trattaro, Vivek Das, Chantal Rencurel, Giuseppe Testa
المصدر: Frontiers in Neuroscience, Vol 16 (2022)
مصطلحات موضوعية: EZH2 (enhancer of zeste homolog 2), H3K27me3 – histone H3 tri-methylated at Lysine 27, neuronal differentiation, PRC2 (Polycomb repressive complex 2), corticogenesis, epigenetics, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Rahal, Farah, Capdevielle, Caroline, Rousseau, Benoit, Yzotte, Julien, Dupuy, Jean-William, Cappellen, David, Chotard, Guillaume, Ménard, Mélissa, Charpentier, Justine, Jecko, Vincent, Caumont, Charline, Gimbert, Edouard, Grosset, Christophe, Hagedorn, Martin
المساهمون: Biothérapies des maladies génétiques et cancers, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Collège Sciences de l'Homme UB, Bordeaux (CSH), Université de Bordeaux (UB), Animalerie A2 Bordeaux, Université Bordeaux Segalen - Bordeaux 2, Plateforme Protéome Bordeaux, Centre Génomique Fonctionnelle Bordeaux Bordeaux (CGFB), Institut Polytechnique de Bordeaux-Université de Bordeaux Ségalen Bordeaux 2 -Institut Polytechnique de Bordeaux-Université de Bordeaux Ségalen Bordeaux 2, Hôpital Pellegrin, CHU Bordeaux-Groupe hospitalier Pellegrin
المصدر: ISSN: 2632-2498 ; Neuro-Oncology Advances ; https://inserm.hal.science/inserm-03598538 ; Neuro-Oncology Advances, 2022, 4 (1), ahead of print. ⟨10.1093/noajnl/vdac018⟩.
مصطلحات موضوعية: EZH2: Enhancer Of Zeste Homolog 2, DMG: Diffuse Midline Glioma, H3K27M-mutant, GSK126, Atorvastatin, Cholesterol metabolism, [SDV]Life Sciences [q-bio], [SDV.CAN]Life Sciences [q-bio]/Cancer
Relation: inserm-03598538; https://inserm.hal.science/inserm-03598538; https://inserm.hal.science/inserm-03598538v2/document; https://inserm.hal.science/inserm-03598538v2/file/Faral%20et%20al,%202022%20NOA%20vdac018.pdf
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6
المؤلفون: Minggang Fang, Sara K. Deibler, Pranathi Meda Krishnamurthy, Feng Wang, Paola Rodriguez, Shahid Banday, Ching-Man Virbasius, Miguel Sena-Esteves, Jonathan K. Watts, Michael R. Green
مصطلحات موضوعية: Neuroscience, Biological Engineering, Developmental Biology, Stem Cells, Artificial Intelligence and Image Processing, Endocrinology, Radiology and Organ Imaging, Autonomic Nervous System, Cellular Nervous System, Central Nervous System, Sensory Systems, Clinical Nursing: Tertiary (Rehabilitative), Decision Making, Rehabilitation Engineering, Biomedical Engineering not elsewhere classified, Signal Processing, Neurogenetics, Image Processing, FXS, FMR1 silencing, FMR1 reactivation, EZH2 (enhancer of zeste homolog 2), ASO - antisense oligonucleotides, neuron differentiation
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7
المؤلفون: Minggang Fang, Sara K. Deibler, Pranathi Meda Krishnamurthy, Feng Wang, Paola Rodriguez, Shahid Banday, Ching-Man Virbasius, Miguel Sena-Esteves, Jonathan K. Watts, Michael R. Green
مصطلحات موضوعية: Neuroscience, Biological Engineering, Developmental Biology, Stem Cells, Artificial Intelligence and Image Processing, Endocrinology, Radiology and Organ Imaging, Autonomic Nervous System, Cellular Nervous System, Central Nervous System, Sensory Systems, Clinical Nursing: Tertiary (Rehabilitative), Decision Making, Rehabilitation Engineering, Biomedical Engineering not elsewhere classified, Signal Processing, Neurogenetics, Image Processing, FXS, FMR1 silencing, FMR1 reactivation, EZH2 (enhancer of zeste homolog 2), ASO - antisense oligonucleotides, neuron differentiation
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8
المؤلفون: Christopher T. Rhodes, Dhanya Asokumar, Mira Sohn, Shovan Naskar, Lielle Elisha, Parker Stevenson, Dongjin R. Lee, Yajun Zhang, Pedro P. Rocha, Ryan K. Dale, Soohyun Lee, Timothy J. Petros
مصطلحات موضوعية: Cell Biology, Neuroscience, Cellular Nervous System, Central Nervous System, Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), Protein Trafficking, interneurons, medial ganglionic eminence (MGE), EZH2 (enhancer of zeste homolog 2), epigenetics, neurodevelopment, single cell sequencing, Cut&Tag, histone methylation
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9
المؤلفون: Christopher T. Rhodes, Dhanya Asokumar, Mira Sohn, Shovan Naskar, Lielle Elisha, Parker Stevenson, Dongjin R. Lee, Yajun Zhang, Pedro P. Rocha, Ryan K. Dale, Soohyun Lee, Timothy J. Petros
مصطلحات موضوعية: Cell Biology, Neuroscience, Cellular Nervous System, Central Nervous System, Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), Protein Trafficking, interneurons, medial ganglionic eminence (MGE), EZH2 (enhancer of zeste homolog 2), epigenetics, neurodevelopment, single cell sequencing, Cut&Tag, histone methylation
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10Academic Journal
المؤلفون: So Masaki, Shun Ikeda, Asuka Hata, Yusuke Shiozawa, Ayana Kon, Seishi Ogawa, Kenji Suzuki, Fumihiko Hakuno, Shin-Ichiro Takahashi, Naoyuki Kataoka
المصدر: Frontiers in Genetics, Vol 10 (2019)
مصطلحات موضوعية: myelodysplastic syndrome, splicing, SRSF2, exonic splicing enhancer, aberrant splicing, EZH2 (enhancer of zeste homolog 2), Genetics, QH426-470
وصف الملف: electronic resource
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11
المؤلفون: Jian Liu, Qi Lv, Yinan Zhang, Yao Xing, Dong Dong, Yue Liu, Lihong Hu, Hongzhi Qiao
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)مصطلحات موضوعية: PMSF, phenylmethanesulfonyl fluoride, MPO, myeloperoxidase, ATG7, autophagy-related protein 7, DMSO, dimethyl sulfoxide, CETSA, cellular thermal shift assay, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, General Pharmacology, Toxicology and Pharmaceutics, M-CSF, macrophage colony stimulating factor, 0303 health sciences, Chemistry, BMDMs, bone marrow-derived macrophages, EZH2, Inflammasome, ELISA, enzyme-linked immunosorbent assay, Colitis, PMA, phorbol myristate acetate, Ulcerative colitis, ChIP, chromatin immunoprecipitation, 030220 oncology & carcinogenesis, Histone methyltransferase, LPS, lipopolysaccharide, Original Article, DAI, disease activity index, medicine.drug, AIM2, absent in melanoma 2, ATP, adenosine triphosphate, ECL, enhanced chemiluminescent, 3-MC, 3-methylcholanthrene, ATG5, RM1-950, macromolecular substances, SIP, solvent-induced protein precipitation, Lonicerin, 03 medical and health sciences, CHX, cycloheximide, FBS, fetal bovine serum, PAMPs, pathogen-associated molecular patterns, DSS, dextran sulfate sodium, Autophagy, medicine, Epigenetics, TEM, transmission electron microscopy, 030304 developmental biology, EDTA, ethylenediaminetetraacetic acid, RMSF, root mean-square fluctuation, RMSD, root mean-square deviation, MDP, muramyldipeptide, medicine.disease, NLRP3 inflammasome, ATG5, autophagy-related protein 5, MSU, monosodium urate crystals, UC, ulcerative colitis, 5-ASA, 5-aminosalicylic acid, DTT, dithiothreitol, DAMPs, damage-associated molecular patterns, H&E, hematoxylin and eosin, Cancer research, Therapeutics. Pharmacology, NLRP3, nucleotide-binding domain-like receptors family pyrin domain containing 3, PRC2, polycomb repressive complex 2
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12
المؤلفون: Xiaohui Pan, Bo Yang, Hongjie Guo, Shuyuan Cheng, Xi Chen, Ling Ding, Qiaojun He, Wenxin Zhang
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 723-733 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: TIM-3, T cell immunoglobulin and mucin domain 3, H3K27me3, tri-methylation of lysine 27 on histone H3, MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, Review, TAA, tumor-associated antigen, DC, dendritic cell, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, LAG-3, lymphocyte activation gene-3, CTLA-4, cytotoxic T lymphocyte antigen 4, Medicine, BETi, bromodomain and extra-terminal motif inhibitors, General Pharmacology, Toxicology and Pharmaceutics, FOXP3, forkhead box P3, HDACi, histone deacetylase inhibitor, Cancer, 0303 health sciences, ACE1, angiotensin converting enzyme, CLL, chronic lymphocytic leukemia, biology, IDO, indoleamine 2,3-dioxygenase, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Tregs, regulatory T cells, PD-L1/PD-1 blockade, CCL22 (MDC), macrophage-derived chemokine, Immunotherapy, TET2, ten-eleven translocation 2, CTLs, cytotoxic T lymphocytes, FDA, U. S. Food and Drug Administration, PD-L1, programmed cell death ligand 1, T cell, CTA, cancer testis antigen, Immune cycle, TIL, tumor infiltrating lymphocytes, Epigenetic regulation, OS, overall survival, 03 medical and health sciences, Immune system, Antigen, PD-L1, TH-1, T helper type 1, DNMT1, DNA methyltransferase 1, MHC, major histocompatibility complex, CX3CL1, C-X3-C motif chemokine ligand 1, IFN-γ, interferon-gamma, 030304 developmental biology, business.industry, lcsh:RM1-950, biochemical phenomena, metabolism, and nutrition, medicine.disease, CXCL, CXC chemokine ligand, Blockade, lcsh:Therapeutics. Pharmacology, APC, antigen-presenting cell, UHRF1, ubiquitin-like PHD and RING finger domain-containing 1, 5-AzaC, 5-azacitidine, ACP1, human red cell acid phosphatase, biology.protein, Cancer research, bacteria, DNMTi, DNA methyltransferase inhibitors, PD-1, programmed cell death 1, business, PRC2, polycomb repressive complex 2
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13
المؤلفون: Farah Rahal, Caroline Capdevielle, Benoit Rousseau, Julien Izotte, Jean-William Dupuy, David Cappellen, Guillaume Chotard, Mélissa Ménard, Justine Charpentier, Vincent Jecko, Charline Caumont, Edouard Gimbert, Christophe F Grosset, Martin Hagedorn
المساهمون: Biothérapies des maladies génétiques et cancers, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Collège Sciences de l'Homme [UB, Bordeaux] (CSH), Université de Bordeaux (UB), Animalerie A2 [Bordeaux], Université Bordeaux Segalen - Bordeaux 2, Plateforme Protéome [Bordeaux], Centre Génomique Fonctionnelle Bordeaux [Bordeaux] (CGFB), Institut Polytechnique de Bordeaux-Université de Bordeaux Ségalen [Bordeaux 2]-Institut Polytechnique de Bordeaux-Université de Bordeaux Ségalen [Bordeaux 2], Hôpital Pellegrin, CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Grosset, Christophe
المصدر: Neuro-Oncology Advances
Neuro-Oncology Advances, Society for NeuroOncology (SNO); the European Association of Neuro-Oncology(EANO); and Oxford University Press, 2022, ahead of print. ⟨10.1093/noajnl/vdac018⟩
Neuro-Oncology Advances, Society for NeuroOncology (SNO); the European Association of Neuro-Oncology(EANO); and Oxford University Press, 2022, 4 (1), ahead of print. ⟨10.1093/noajnl/vdac018⟩مصطلحات موضوعية: [SDV] Life Sciences [q-bio], [SDV.CAN] Life Sciences [q-bio]/Cancer, H3K27M-mutant, [SDV]Life Sciences [q-bio], Atorvastatin, EZH2: Enhancer Of Zeste Homolog 2, Cholesterol metabolism, [SDV.CAN]Life Sciences [q-bio]/Cancer, GSK126, DMG: Diffuse Midline Glioma
وصف الملف: application/pdf
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14
المؤلفون: Guiquan Zhu, Chuanshi He, Linlin Wang, Ling Li
المصدر: Translational Oncology, Vol 14, Iss 12, Pp 101231-(2021)
Translational Oncologyمصطلحات موضوعية: GAS6, growth retardant specific protein 6, Cancer Research, ER, estrogen receptor, SACC, salivary adenoid cystic carcinoma, TNFR1, tumor necrosis factor receptor 1, HPLF, human periodontal ligament fibroblast, MSC, mesenchymal stem cell, Review, FGF5, fibroblast growth factor 5, HNSCC, head and neck squamous cell carcinoma, NID1, Nidogen 1, Signal transduction, Metastasis, lncRNA, long non-coding RNA, Extracellular matrix, EZH2, enhancer of zeste homolog 2, HUVEC, human umbilical vein endothelial cell, GDF15, growth differentiation factor 15, RC254-282, Treg, cell regulatory T cell, ncRNA, non-coding RNA, VASH1, vasohibin 1, CAV1, caveolin 1, LIF, leukemia inhibitory factor, PDGFRS, platelet-derived growth factor receptor, TME, tumor microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, FAP, fibroblast activating protein, Extracellular vesicle, VEGF, vascular endothelial growth factor, ECM, extracellular matrix, MCC, Merkel cell carcinogenic, Oncology, Tumor microenvironment, CRC, colorectal cancer, MVB, multivesicular body, TP53InP1, TP53-induced nucleoprotein 1, CSCC, cervical squamous cell carcinoma, EMT, epithelial-mesenchymal transition, JAK, Janus kinase, Stromal cell, NGF, nerve growth factor, PRSC, prostatic stromal cell, Biology, TNBC, triple-negative breast cancer, CTGF, connective tissue growth factor, α-SMA, α-smooth muscle actin, CM, conditioned medium, EV, extracellular vesicle, medicine, OSCC, oral squamous cell carcinoma, FN, fibronectin, tTG, tissue transglutaminase, Cancer-associated fibroblasts, CAF, cancer-associated fibroblast, ILV, intracavinal vesicle, CCAL, colorectal cancer-associated lncRNA, HL, Hodgkin's lymphoma, medicine.disease, SRF, serum response factor, YAP1, YES-associated protein 1, CYR61, cysteine-rich angiogenesis inducer 61, PAF, paracancerous fibroblast, SNARE, soluble NSF-attachment protein receptor, Tumor progression, Cancer cell, Cancer research, Cancer-Associated Fibroblasts, CSD, CAV1 scaffolding domain, HGF, hepatocyte growth factor, HCC, hepatocellular carcinoma
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15Data_Sheet_1_EZH2-Mediated H3K27me3 Targets Transcriptional Circuits of Neuronal Differentiation.zip
المؤلفون: Serena Buontempo, Pasquale Laise, James M. Hughes, Sebastiano Trattaro, Vivek Das, Chantal Rencurel, Giuseppe Testa
مصطلحات موضوعية: Neuroscience, Biological Engineering, Developmental Biology, Stem Cells, Artificial Intelligence and Image Processing, Endocrinology, Radiology and Organ Imaging, Autonomic Nervous System, Cellular Nervous System, Central Nervous System, Sensory Systems, Clinical Nursing: Tertiary (Rehabilitative), Decision Making, Rehabilitation Engineering, Biomedical Engineering not elsewhere classified, Signal Processing, Neurogenetics, Image Processing, EZH2 (enhancer of zeste homolog 2), H3K27me3 – histone H3 tri-methylated at Lysine 27, neuronal differentiation, PRC2 (Polycomb repressive complex 2), corticogenesis, epigenetics, transcriptomics, Prdm13
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16
المؤلفون: Jose J.G. Marin, Maria J. Monte, Malgorzata Milkiewicz, Miren Bravo, Fernando Lopitz-Otsoa, Javier Crespo, Carlos Ferre-Aracil, Sofia Lachiondo-Ortega, Virginia Gutiérrez-de-Juan, Marta Varela-Rey, Jose Luis Calleja, Teresa C. Delgado, María L. Martínez-Chantar, Mercedes Robles, Piotr Milkiewicz, Marina Serrano-Macia, Pablo Fernández-Tussy, Juan Anguita, Marcos López-Hoyos, Shelly C. Lu, David Fernández-Ramos, Naroa Goikoetxea-Usandizaga, Paula Iruzubieta, Natalia Elguezabal, Lucía Barbier-Torres, Jorge Simón, Mercedes Rincon
المساهمون: Universidad de Cantabria
المصدر: JHEP Reports, Vol 3, Iss 3, Pp 100276-(2021)
JHEP Reports Volume 3, Issue 3, June 2021, 100276
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
JHEP Reportsمصطلحات موضوعية: Mitochondrial ROS, MMP, mitochondrial membrane potential, LSM, liver stiffness, MPO, myeloperoxidase, AST, aspartate aminotransferase, Pgc1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha, RC799-869, Pharmacology, p-JNK, phosphor-JNK, TNF, tumour necrosis factor, Tfam, transcription factor A mitochondrial, Ccr5, C-C motif chemokine receptor 5, Immunology and Allergy, CLD, cholestatic liver disease, MLKL, mixed-lineage kinase domain-like pseudokinase, shRNA, small hairpin RNA, ANA, antinuclear antibodies, Hif-1α, hypoxia-inducible factor 1-alpha, Liver injury, GCDCA, glycochenodeoxycholic acid, Cholestasis, Bile acid, MCJ, methylation-controlled J, SDH2, succinate dehydrogenase, Gastroenterology, α-SMA, alpha-smooth muscle actin, Pgc1β, peroxisome proliferator-activated receptor gamma coactivator 1-beta, ROS, Bile duct ligation, Diseases of the digestive system. Gastroenterology, Mitochondria, Ccr2, C-C motif chemokine receptor 2, Ezh2, enhancer of zeste homolog 2, Mitochondrial respiratory chain, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, JNK, c-Jun N-terminal kinase, BA, bile acid, BAX, BCL2 associated X, RT, room temperature, VCTE, vibration-controlled transient elastography, HSC, hepatic stellate cells, Research Article, PARP, poly (ADP-ribose) polymerase, Cxcl1, C-X-C motif chemokine ligand 1, p-MLKL, phosphor-MLKL, medicine.drug_class, mRNA, messenger ribonucleic acid, ETC, electron transport chain, Nrf1, nuclear respiratory factor 1, APRI, AST to platelet ratio index, BDL, bile duct ligation, Ccl2, C-C motif chemokine ligand 2, MPT, mitochondrial permeability transition, UDCA, ursodeoxycholic acid, Primary sclerosing cholangitis, AMA-M2, antimitochondrial M2 antibody, ROS, reactive oxygen species, BCL-Xl, B-cell lymphoma-extra large, ALT, alanine aminotransferase, Internal Medicine, medicine, Trail, TNF-related apoptosis-inducing ligand, tBIL, total bilirubin, KO, knockout, ALP, alkaline phosphatase, Hepatology, business.industry, medicine.disease, WT, wild-type, MCJ, PSC, primary sclerosing cholangitis, DCA, deoxycholic acid, Mitochondrial permeability transition pore, siRNA, small interfering RNA, Ucp2, uncoupling protein 2, Fxr, farnesoid X receptor, Hepatic stellate cell, PBC, primary biliary cholangitis, business, Cyp7α1, cholesterol 7 alpha-hydroxylase, BCL-2, B-cell lymphoma 2, MAPK, mitogen-activated protein kinase, Abs, antibodies
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17
المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 160-176 (2019)مصطلحات موضوعية: cIAP1, cellular inhibitor of apoptosis protein, BTK, Bruton's tyrosine kinase, HDAC, histone deacetylase, Review Article, PROTAC, proteolysis targeting chimeras, HTS, high-throughput screening, PI3K, phosphatidylinositol-3-kinase, VHL, Von Hippel-Lindau, Biochemistry, GST, glutathione S-transferase, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, Structural Biology, BET, bromodomain and extra-terminal, GCN5, general control nonderepressible 5, POI, protein of interest, TBK1, TANK-Binding kinase 1, CRBN, Cereblon, DC50, the compound concentration that results in 50% target protein degradation, FLT3, FMS-like tyrosine kinase-3, 0303 health sciences, biology, Chemistry, Drug discovery, ABCB1, ATP-binding cassette sub-family B member 1, Small molecule, Computer Science Applications, Cell biology, Ubiquitin ligase, AHR, aryl hydrogen receptor, FRS2, fibroblast growth factor receptor substrate 2, RIPK2, receptor-interacting serine/threonine-protein kinase 2, 030220 oncology & carcinogenesis, Proteome, AD, Alzheimer's disease, ERK1, extracellular signal-regulated kinase 1, MDM2, mouse double-minute 2 homolog, RTK, receptor tyrosine kinase, ERα, estrogen receptor alpha, TRIM24, tripartite motif-containing 24 (also known as TIF1α), Biotechnology, DHODH, Dihydroorotate dehydrogenase, lcsh:Biotechnology, Biophysics, Protein degradation, Bivalent ligand, Bcl6, B-cell lymphoma 6, CLIPTAC, click-formed proteolysis targeting chimera, PROTAC, 03 medical and health sciences, CDK9, cyclin dependent kinase 9, ERRα, estrogen-related receptor alpha, lcsh:TP248.13-248.65, Genetics, SARM, selective androgen receptor modulator, Transcription factor, PEG, polyethylene glycol, 030304 developmental biology, PLK-1, polo-like kinase 1, PCAF, P300/CBP-associated factor, Proteasome, Brd4, bromodomain 4, MetAP-2, methionine aminopeptidase-2, Chimera, ALK, anaplastic lymphoma kinase, Cereblon, CK2, Casein kinase 2, Degrader, Aβ, amyloid-β, SNIPER, specific and non-genetic IAP-dependent protein eraser, GPCR, G-protein coupled receptor, RAR, retinoic acid receptor, biology.protein
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18
المؤلفون: Gwen Lomberk, Adebowale O. Bamidele, Mary R. Sagstetter, Manuel Bonfim Braga Neto, Olga F. Sarmento, Subra Kugathasan, Raul Urrutia, Michelle Gonzalez, William A. Faubion, Phyllis A. Svingen
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 55-71 (2019)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: Male, 0301 basic medicine, Cell Separation, T-Lymphocytes, Regulatory, Regulatory T Cells, Jurkat Cells, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, co-IP, co-immunoprecipitation, Phosphorylation, Original Research, IBD, inflammatory bowel disease, Janus kinase 1, biology, Chemistry, EZH2, Polycomb Repressive Complex 2, Gastroenterology, FOXP3, Forkhead Transcription Factors, H3K27me3, trimethylated histone H3 at lysine 27, hemic and immune systems, C232, cysteine 232, Middle Aged, Proinflammatory Cytokine, 3. Good health, Chromatin, Intestines, STAT, signal transducer and activator of transcription, medicine.anatomical_structure, Female, Epigenetics, 030211 gastroenterology & hepatology, ChIP, chromatin-immunoprecipitation, JAK, Janus kinase, Co-Repressor Proteins, Protein Binding, Signal Transduction, Crohn’s Disease, Adult, STAT3 Transcription Factor, PMA, phorbol 12-myristate 13-acetate, PBMC, peripheral blood mononuclear cell, Regulatory T cell, PBS, phosphate-buffered saline, SUZ12, suppressor of zeste, Treg, regulatory T cell, chemical and pharmacologic phenomena, macromolecular substances, Proinflammatory cytokine, 03 medical and health sciences, EED, embryonic ectoderm development, CD, Crohn’s disease, medicine, Animals, Humans, LZ, leucine zipper, Enhancer of Zeste Homolog 2 Protein, lcsh:RC799-869, Phosphotyrosine, Interleukin 6, Th, T helper, Transcription factor, Janus Kinases, Cell Nucleus, Inflammation, FOXP3, forkhead domain-containing X-chromosome–encoded protein, Hepatology, Interleukin-6, PLA, proximity ligation assay, Inflammatory Bowel Diseases, WT, wild-type, IL, interleukin, Mice, Inbred C57BL, 030104 developmental biology, Mutation, IPEX, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, biology.protein, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, FCS, fetal calf serum, PRC2, polycomb repressive complex 2
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19
المؤلفون: Jia-Jia Zhou, Di Cheng, Junge Deng, Xiao-Yu He, Bin Zhang, Zhe Meng, Xiao-Geng Deng, Guolin Li, Huilin Ye, Rufu Chen, Shangyou Zheng, Lusheng Wei
المصدر: EBioMedicine
مصطلحات موضوعية: 0301 basic medicine, Research paper, Hepatocellular carcinoma, Epigenesis, Genetic, lncRNA, long non-coding RNA, Mice, 0302 clinical medicine, Cell Movement, EZH2, Enhancer of zeste homolog 2, MiR-122, Promoter Regions, Genetic, CCNG1, Cyclin G1, Gene knockdown, DNA methylation, Cell Cycle, Liver Neoplasms, EZH2, HOTAIR, General Medicine, HOTAIR, Homeobox transcript antisense intergenic RNA, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Female, RNA Interference, RNA, Long Noncoding, Epigenetics, Carcinoma, Hepatocellular, Cyclin G1, Biology, Models, Biological, DNA methyltransferase, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cell Line, Tumor, microRNA, Animals, Humans, Cell Proliferation, Base Sequence, miR-122, microRNA-122, microRNA-122, LncRNA HOTAIR, Xenograft Model Antitumor Assays, Disease Models, Animal, MicroRNAs, 030104 developmental biology, DNMT, DNA methyltransferase, Cancer research, HCC, hepatocellular carcinoma
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20
المؤلفون: Xiangyan Zhang, Xiangli Ma, Quanxin Wang, Zhaolu Kong
المصدر: Translational Oncology
Translational Oncology, Vol 16, Iss, Pp 101316-(2022)مصطلحات موضوعية: Cancer Research, Bladder cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, ARR, Aquired Radio-Resistance, BCa, Bladder Cancer, macromolecular substances, EZH2, Enhancer of Zeste Homolog 2, Radiosensitivity, Oncology, Autophagy, EZH2, skin and connective tissue diseases, RC254-282, Original Research, Acquired radio-resistance
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