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المؤلفون: Andrew Brennan, Robert Layfield, Jed Long, Huw E.L. Williams, Neil J. Oldham, Daniel Scott, Mark S. Searle
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: autophagy, amyotrophic lateral sclerosis, hATG8, SQSTM1/p62, p62, SQSTM1/p62, Autophagy-Related Proteins, Biochemistry, ESI-MS, electrospray ionization–mass spectrometry, FTLD, frontotemporal lobar degeneration, Sequestosome-1 Protein, AIM, Humans, NMR, nuclear magnetic resonance, Molecular Biology, GABARAP, γ-aminobutyric acid receptor associated protein, hATG8, human autophagy-related 8, ITC, isothermal titration calorimetry, UBA, ubiquitin-associated, Autophagy-Related Protein 8 Family, Cell Biology, AIM, ATG8-interacting motif, ALS, amyotrophic lateral sclerosis, CSP, chemical shift perturbation, LC3, microtubule-associated protein 1A/1B light chain 3, Apoptosis Regulatory Proteins, Microtubule-Associated Proteins, Research Article
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المؤلفون: Samuel N. Snyder, Piotr J. Mak
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: protein chemistry, MhuD, Mtb, Mycobacterium tuberculosis, Heme, 6cHS, 6-coordinated high spin, Biochemistry, enzyme catalysis, Mixed Function Oxygenases, Structure-Activity Relationship, 6cLS, 6-coordinated low spin, oop, out-of-plane, Bacterial Proteins, Catalytic Domain, diheme, HO, heme oxygenase, ESI-MS, electrospray ionization mass spectrometry, Molecular Biology, His, histidine, PPIX, protoporphyrin IX, Carbon Monoxide, POR, NADPH-cytochrome P450 oxidoreductase, Cell Biology, Mycobacterium tuberculosis, rR, resonance Raman, heme oxygenase, hHO-1, human heme oxygenase-1, 5cHS, 5-coordinated high spin, LF, low frequency, UV-vis, ultraviolet-visible, Raman spectroscopy, HF, high frequency, Research Article
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المؤلفون: Usha Yadav, Garima, Monica Sundd, Rashima Prem
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: CoA, coenzyme A, Protein Conformation, alpha-Helical, Conformational change, DSS, sodium 4,4-dimethyl-4-silapentanesulfonate, SEC, size-exclusion chromatography, Saccharomyces cerevisiae Proteins, ACP, acyl carrier protein, HSQC, heteronuclear single quantum coherence spectroscopy, Stereochemistry, fatty acid biosynthesis, Coenzyme A, Saccharomyces cerevisiae, Amino Acid Motifs, acyl carrier protein, Biochemistry, Turn (biochemistry), chemistry.chemical_compound, ESI-MS, electrospray ionization–mass spectrometry, chemical shift perturbations, type I ACP, Threonine, NMR, nuclear magnetic resonance, Molecular Biology, Nuclear Magnetic Resonance, Biomolecular, S. cerevisiae ACP, 4′-PP, 4′-phosphopantetheine, biology, Chemistry, FAS, fatty acid synthesis, ScACP, Saccharomyces cerevisiae acyl carrier protein, type I FAS, Cell Biology, biology.organism_classification, NMR, Acyl carrier protein, acyl chain sequestration, Helix, biology.protein, acyl-ACP interaction, lipids (amino acids, peptides, and proteins), Heteronuclear single quantum coherence spectroscopy, Research Article
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5GH18 endo-β-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans
المؤلفون: Jonathan J. Du, Chao Li, Mikel García-Alija, Eric J. Sundberg, Beatriz Trastoy, Erik H. Klontz, Thomas C. Donahue, Lai-Xi Wang, Blaine R. Roberts, Marcelo E. Guerin
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Glycan, Glycosylation, Mutagenesis (molecular biology technique), gut microbiome, Hy-type, hybrid type, Crystallography, X-Ray, Biochemistry, endo-β-N-acetylglucosaminidases, Substrate Specificity, chemistry.chemical_compound, Molecular recognition, Polysaccharides, Glycoside hydrolase, enzyme specificity, ESI-MS, electrospray ionization mass spectrometry, Molecular Biology, chemistry.chemical_classification, HM-type, high-mannose type, biology, antibody glycoengineering, carbohydrate active enzymes, Cell Biology, glycoprotein bioengineering, Alanine scanning, CT-type, complex type, carbohydrates (lipids), Molecular Docking Simulation, Bacteroides thetaiotaomicron, Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase, chemistry, biology.protein, glycoside hydrolases, ENGase, endo-β-N-acetylglucosaminidase, Protein folding, Protein Structural Elements, Glycoprotein, Research Article
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المؤلفون: George V. Popescu, Sorina C. Popescu, Leslie M. Hicks, Anthony A. Iannetta, Thualfeqar Al-Mohanna, Najmeh Setareh Nejat
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, SEC, size-exclusion chromatography, Protein Conformation, Thioredoxin reductase, Mutant, Arabidopsis, Pseudomonas syringae, thimet oligopeptidase, Protein Sorting Signals, medicine.disease_cause, Biochemistry, 03 medical and health sciences, Immune system, ESI-MS, electrospray ionization–mass spectrometry, ROS, reactive oxygen species, medicine, GSH, glutathione, Arabidopsis thaliana, redox-sensitive thiol, Molecular Biology, OOP, organellar oligopeptidase, ETI, effector-triggered immunity, Thimet oligopeptidase, 030102 biochemistry & molecular biology, biology, Chemistry, TOP, thimet oligopeptidase, oxidative activation, Metalloendopeptidases, Cell Biology, biology.organism_classification, Cell biology, 030104 developmental biology, Mutation, SAR, systemic acquired response, Effector-triggered immunity, Reactive Oxygen Species, Oxidation-Reduction, Oxidative stress, NTRC, NADPH-dependent thioredoxin reductase C, Signal Transduction, Research Article, disulfide
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المؤلفون: Dayanand Kalyani, Markus M. Keskitalo, Henrik Aspeborg, Tom Reichenbach, Julian Conrad, Christina Divne
المصدر: Journal of Structural Biology: X, Vol 5, Iss, Pp 100048-(2021)
Journal of Structural Biology: Xمصطلحات موضوعية: Mannosidase, Reticulitermes, Structural Biology, TCEP, tris (2-carboxyethyl) phosphine hydrochloride, Glycoside hydrolase, Fuc, fucopyranoside, Xyl, xylopyranoside, Biology (General), HPAEC-PAD, High Performance Anion Exchange Chromatography and Pulsed Amperometric Detection, Gal, galactopyranoside, SDS-PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis, Mannan, biology, Termite hindgut, Chemistry, food and beverages, Hindgut, IPTG, β-D-1-thiogalactopyranoside, MWCO, molecular weight cut-off, Glycosyl hydrolase family 5, CAZy, Carbohydrate-Active enZymes database, Biochemistry, Bacteroides salyersiae, SEC, size-exclusion chromatography, cryo-EM, electron cryo-microscopy, 4-mannosidase, QH301-705.5, Article, Electron cryo-microscopy, Glc, glucopyranoside, MOS, mannooligosaccharides, Reticulitermes flavipes, Verrucomicrobia, GH, glycoside hydrolase, ESI-MS, electrospray ionization mass spectrometry, ComputingMethodologies_COMPUTERGRAPHICS, EDTA, ethylenediaminetetraacetic acid, CMC, carboxymethyl cellulose, Glycoside hydrolase family 5, Crystal structure, Opitutaceae, HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid, Op5Man5, exo-β-1,4-mannosidase from Opitutaceae bacterium strain TAV5, DP, degree of polymerization, TLC, thin-layer chromatography, biology.organism_classification, GlcNAc, N-acetyl glucosamine, LBG, locust bean gum, Exo-β-1, pNP, p-nitrophenyl, Man, mannopyranoside
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المؤلفون: Norin Nabil Hamouda, Steven H. L. Verhelst, Mujahid Azfar, Chris Van den Haute, Jan Eggermont, Patrizia Agostinis, Álvaro Cortés Calabuig, Rupert L. Mayer, Ragna Sannerud, Veerle Baekelandt, Johannes V. Swinnen, Francis Impens, Roeland Vanhoutte, Shaun Martin, Wim Annaert, Peter Vangheluwe
المصدر: JOURNAL OF BIOLOGICAL CHEMISTRY
The Journal of Biological Chemistryمصطلحات موضوعية: 0301 basic medicine, PTS, polyamine transport system, Mitoguazone, BV, benzyl viologen, Spermine, polyamine transport system, Biochemistry, chemistry.chemical_compound, ATP13A3, polyamine, Cricetinae, Polyamines, LAMP1, lysosomal-associated membrane protein 1, Medicine and Health Sciences, P-type ATPase, putrescine, ESI-MS, electrospray ionization-mass spectrometry, Enzyme Inhibitors, ATP13A2, FA, formic acid, Adenosine Triphosphatases, Gene knockdown, Chemistry, Chinese hamster ovary cell, SPD, spermidine, RAB7/11, ras-associated binding protein 7/11, DCM, dichloromethane, transporter, Putrescine transport, DFMO, difluoromethylornithine, Research Article, P5B-ATPase, FDR, false discovery rate, DPBS-T, DPBS containing 0.1% Tween 20, EEA1, early endosomal antigen 1, CHO Cells, BODIPY, boron dipyrromethene, CHO, Chinese hamster ovary, SPM, spermine, 03 medical and health sciences, Cricetulus, FBS, fetal bovine serum, Putrescine, Animals, ATPase, APols, amphipol, MGBG, methylglyoxal bis-(guanylhydrazone), PUT, putrescine, Molecular Biology, endosome, DPBS, Dulbecco's PBS, 030102 biochemistry & molecular biology, Polyamine transport, Whole Genome Sequencing, Membrane Transport Proteins, Biological Transport, Cell Biology, Spermidine, 030104 developmental biology, Mutation, transport, BSA, bovine serum albumin, DAPI, 4',6-diamidino-2-phenylindole, Polyamine
وصف الملف: Print-Electronic; application/pdf
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المؤلفون: Christian F. W. Becker, Xue Wen Ng, Stefanie Hackl, Danqin Lu, Thorsten Wohland
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, HBSS, Hanks' Balanced Salt Solution, PrPSc Proteins, Glycosylphosphatidylinositols, animal diseases, Cell, ROI, region of interest, TSE, transmissible spongiform encephalopathy, Scrapie, fluorescence correlation spectroscopy, Protein aggregation, Biochemistry, Prion Diseases, ESI-MS, electrospray ionization–mass spectrometry, PrPC, cellular prion protein, mβCD, methyl-β-cyclodextrin, EPL, expressed protein ligation, Cluster Analysis, Protein Isoforms, Cytoskeleton, CD, circular dichroism, SDS-PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis, TIS, triisopropylsilane, Neurons, Transmissible spongiform encephalopathy, Chemistry, cytoskeleton, ICQ, intensity correlation quotient, Cell biology, DCM, dichloromethane, FCS, fluorescence correlation spectroscopy, PrPSc, scrapie prion protein, medicine.anatomical_structure, PCC, Pearson's correlation coefficient, PSF, point spread function, Research Article, CBD, chitin-binding domain, RP-HPLC, reversed-phase high-performance liquid chromatography, GPI, glycosylphosphatidylinositol, EMCCD, electron multiplying charge-coupled device, SR-SIM, superresolution structured illumination microscopy, Prions, TCA, trichloroacetic acid, Prion Proteins, ITIR-FCS, imaging total internal reflection–FCS, Cell Line, protein aggregation, 03 medical and health sciences, SPPS, solid-phase peptide synthesis, medicine, CDI, carbonyldiimidazole, Humans, Molecular Biology, Actin, 030102 biochemistry & molecular biology, Cell Membrane, Membrane Proteins, Cell Biology, Actin cytoskeleton, medicine.disease, CCF, cross-correlation function, Actins, nervous system diseases, EGFR, epidermal growth factor receptor, membrane-associated proteins, 030104 developmental biology, ICA, intensity correlation analysis, ACF, autocorrelation function, prion protein, Membrane biophysics, membrane biophysics, protein semisynthesis
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المؤلفون: Shigenori Kanaya, Nobuaki Okumura, Tomoshige Ando, Toshifumi Takao, Nujarin Jongruja, Kosuke Morikawa
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, RNase P, Stereochemistry, Cations, Divalent, Electrospray ionization, Metal ions in aqueous solution, Endoribonuclease, Ribonuclease H, Biochemistry, RF, radio-frequency, Catalysis, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, metal ion–protein interaction, ESI-MS, electrospray ionization–mass spectrometry, Endoribonucleases, Escherichia coli, Magnesium, mass spectrometry (MS), Ribonuclease, HIV-1, human immunodeficiency virus type-1, Molecular Biology, Ternary complex, Ions, Manganese, Binding Sites, 030102 biochemistry & molecular biology, biology, Escherichia coli Proteins, Hydrolysis, zinc, EDTA, ethylenediaminetetraacetate, TEA, Triethylamine, Substrate (chemistry), Cell Biology, DNA, Kinetics, 030104 developmental biology, chemistry, DTT, dithiothreitol, HPLC, high-performance liquid chromatography, RT, reverse transcriptase, biology.protein, RNA, ribonuclease, Research Article
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المؤلفون: Frank Gondelaud, Fabien Chirot, Adam Liwo, Sylvie Ricard-Blum, Aurélien Le Fèvre, Bertrand Duclos, Adriana E. Miele, Mathilde Bouakil
المساهمون: Architecture et fonction des macromolécules biologiques (AFMB), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Spectrométrie des biomolécules et agrégats (SPECTROBIO), Institut Lumière Matière [Villeurbanne] (ILM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institut des Sciences Analytiques (ISA), Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Biophysics of complex systems, Université de Lyon-Université de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), ANABIO-MS - Analyse biomoléculaire par spectrométrie de masse - Biological Analysis by Mass Spectrometry, Catalyse Synthèse et Environnement (CASYEN), Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), Université de Lyon-Université de Lyon-École Supérieure de Chimie Physique Électronique de Lyon (CPE)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), University of Gdańsk (UG), Assemblages Supramoléculaires Péricellulaires et Extracellulaires (ASPE)
المصدر: Matrix Biology Plus
Matrix Biology Plus, 2021, 12 (3-4), pp.100081. ⟨10.1016/j.mbplus.2021.100081⟩
'Matrix Biology Plus ', vol: 12, pages: 100081-1-100081-19 (2021)
Matrix Biology Plus, Vol 12, Iss, Pp 100081-(2021)مصطلحات موضوعية: IDP, GAG, glycosaminoglycan, random-coil, SDC, Biochemistry, TFE, trifluoroethanol, Syndecan 1, SAXS, small angle X-ray scattering, ESI-MS, electrospray ionization - mass spectrometry, Special Section on Molecular and Supramolecular structure of the extracellular matrix, Edited by Sylvie Ricard-Blum, solvent accessible surface area, Biology (General), collision cross section, CD, circular dichroism, ectodomain, SASA, SDS, TFE, trifluoroethanol, DLS, dynamic light scattering, GAG, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, Chemistry, Extracellular matrix assembly, cell-matrix interactions, RC, random-coil, dynamic light scattering, size exclusion chromatography, electrospray ionization - ion mobility - mass spectrometry, SAXS, SEC, CSD, charge state distribution, CD, Ectodomain, sodium dodecyl sulfate, embryonic structures, conformations, ED, ectodomain, DTT, charge state distribution, animal structures, SDS, sodium dodecyl sulfate, Syndecans, Histology, QH301-705.5, PMG, pre-molten globule, DLS, small angle X-ray scattering, Integrin, Biophysics, MoRF, molecular recognition feature, MoRF, IDP, intrinsically disordered protein, Intrinsically disordered proteins, CSD, Growth factor receptor, SDC, syndecan, ESI-IM-MS, Cell surface receptor, glycosaminoglycan, Genetics, ESI-IM-MS, electrospray ionization - ion mobility - mass spectrometry, Cell adhesion, electrospray ionization - mass spectrometry, Molecular Biology, PAGE, polyacrylamide gel electrophoresis, CCS, collision cross section, DTT, dithiothreitol, SASA, solvent accessible surface area, SEC, size exclusion chromatography, molecular recognition feature, PMG, dithiothreitol, ESI-MS, Cell Biology, intrinsically disordered protein, ED, CCS, circular dichroism, PAGE, carbohydrates (lipids), biology.protein, pre-molten globule, polyacrylamide gel electrophoresis, RC, syndecan
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المؤلفون: Weili Zhao, Haisheng He, Yi Lu, Jianping Qi, Xiaochun Dong, Wei Wu
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 8, Iss 1, Pp 97-105 (2018)مصطلحات موضوعية: 1H NMR, 1H nuclear magnetic resonance, medicine.medical_treatment, 02 engineering and technology, Pharmacology, AAC, area above the curve, 030226 pharmacology & pharmacy, chemistry.chemical_compound, 0302 clinical medicine, SIF, simulated intestinal fluid, Insulin, Thiamine, General Pharmacology, Toxicology and Pharmaceutics, VB1, vitamin B1, EE, entrapment efficiency, CDI, N,Nʹ-carbonyldiimidazole, HPLC/UV, high-performance liquid chromatography/ultraviolet, Liposome, CH, cholesterol, DMAP, dimethylaminopyridine, 021001 nanoscience & nanotechnology, TH, thiamine, TH-Lip, thiamine-decorated liposomes, Drug delivery, Original Article, Biomimetic, DMF, dimethylformamide, 0210 nano-technology, Niacin, medicine.drug, Oral, Vitamin, EDC, N-ethyl-Nʹ-(3-dimethylaminopropyl) carbodiimide, SPC, soybean phosphatidylcholine, USP, United States Pharmacopeia, FAE, follicle-associated epithelia, 03 medical and health sciences, NA, niacin, medicine, ESI-MS, electrospray ionization mass spectrometry, SGF, simulated gastric fluid, INS, insulin, CH-Lip, conventional (cholesterol) liposomes, lcsh:RM1-950, GIT, gastrointestinal tract, NA-Lip, niacin liposomes, Streptozotocin, lcsh:Therapeutics. Pharmacology, chemistry, Liposomes, Nanocarriers
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المؤلفون: Burt G van der Boom, Patrick Van Berkel, Patrick J. Engelberts, Paul W. H. I. Parren, Ronald P. Taylor, Marleen Voorhorst, Margaret A. Lindorfer, Rob N. de Jong, Frank J. Beurskens, Ewald T. J. van den Bremer, Erika M. Cook
المصدر: mAbs
mAbs, 7(4), 672-680
van den Bremer, E T J, Beurskens, F J, Voorhorst, M, Engelberts, P J, de Jong, R N, van der Boom, B G, Cook, E M, Lindorfer, M A, Taylor, R P, van Berkel, P H C & Parren, P W H I 2015, ' Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation ', mAbs, vol. 7, no. 4, pp. 672-680 . https://doi.org/10.1080/19420862.2015.1046665مصطلحات موضوعية: capillary isoelectric focusing, Cytotoxicity, Immunologic, Immunology, Mutant, Mutation, Missense, electrospray ionization mass spectrometry, antibody-dependent cell-mediated cytotoxicity, Random hexamer, Report, Humans, Immunology and Allergy, Cytotoxic T cell, isoelectric focusing, Cytotoxicity, complement activation herapeutic antibody post-translational control ADCC antibody-dependent cell-mediated cytotoxicity CDC complement-dependent cytotoxicity CEX cation-exchange cIEF capillary isoelectric focusing CPB carboxy peptidase B ESI-MS electrospray ionization mass spectrometry IEF isoelectric focusing SDS-PAGE sodium dodecyl sulfate polyacrylamide gel electrophoresis HUMAN MONOCLONAL-ANTIBODY MAMMALIAN-CELL CULTURE MASS-SPECTROMETRY IN-VIVO THERAPEUTIC ANTIBODIES CHARGE VARIANTS BINDING-SITE RECOMBINANT PROTEINS MOLECULE, complement-dependent cytotoxicity, cation-exchange, Opsonin, post-translational control, sodium dodecyl sulfate polyacrylamide gel electrophoresis, complement activation, biology, Chemistry, IEF, Complement C1q, Lysine, CPB, ESI-MS, Antibodies, Monoclonal, CEX, Carboxypeptidase, Molecular biology, Complement system, cIEF, HEK293 Cells, Amino Acid Substitution, Immunoglobulin G, biology.protein, carboxy peptidase B, herapeutic antibody, bacteria, Antibody, ADCC, CDC, SDS-PAGE
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المؤلفون: Bob, Schiffrin, Antonio N, Calabrese, Anna J, Higgins, Julia R, Humes, Alison E, Ashcroft, Antreas C, Kalli, David J, Brockwell, Sheena E, Radford
المصدر: Journal of Molecular Biology
مصطلحات موضوعية: Protein Folding, native mass spectrometry, MST, microscale thermophoresis, OMP biogenesis, ESI–MS, electrospray ionization–mass spectrometry, Molecular Dynamics Simulation, Article, DTPC, 1,2-ditridecanoyl-sn-glycero-3-phosphocholine, Skp and SurA, Escherichia coli, CG-MD, coarse-grained molecular dynamics, DMPC, 1,2-dimyristoyl-sn-glycero-3-phosphocholine, folding kinetics, OM, outer membrane, OMP, outer-membrane protein, Escherichia coli Proteins, Cell Membrane, POTRA, polypeptide transport-associated, DUPC, 1,2-diundecanoyl-sn-glycero-3-phosphocholine, Kinetics, tOmpA, transmembrane domain of OmpA, coarse-grained molecular dynamics simulations, Liposomes, Periplasm, Biocatalysis, DLPC, 1,2-dilauroyl-sn-glycero-3-phosphocholine, tBamA, transmembrane domain of BamA, Hydrophobic and Hydrophilic Interactions, BAM, β-barrel assembly machinery, LUV, Large Unilamellar Vesicle, Bacterial Outer Membrane Proteins, Molecular Chaperones
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المؤلفون: Cédric Bernard, Qian Wang, May Poh Lai, Judith Storch, Samar Rizk, Ruth E. Stark, David Kam
المصدر: Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 318-324 (2017)مصطلحات موضوعية: 0301 basic medicine, Protein family, TCEP, tris(2-carboxyethyl)phosphine, TOCSY, 2D Total correlation spectroscopy, AFABP, adipose fatty acid-binding protein, Biophysics, Peroxisome proliferator-activated receptor, PPAR, peroxisome proliferator-activated receptor, Ligand, NMR, Nuclear Magnetic Resonance, Biochemistry, Fatty acid-binding protein, Protein–protein interaction, lcsh:Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, GF, Gel filtration chromatography, lcsh:QD415-436, Homodimer, lcsh:QH301-705.5, Delipidation, chemistry.chemical_classification, Disulfide bond, 030102 biochemistry & molecular biology, Protein, HSQC, [1H–15N] heteronuclear single quantum correlation spectroscopy, FABP, fatty acid-binding protein, Peroxisome, Ligand (biochemistry), NOESY, 2D nuclear Overhauser spectroscopy, 3. Good health, 030104 developmental biology, chemistry, lcsh:Biology (General), ESI-MS, Electrospray Ionization Mass Spectrometry, MALDI-TOF, Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, TCEP, LCFA, Long-chain fatty acid, TEV, Tobacco Etch Virus, Heteronuclear single quantum coherence spectroscopy, Research Article
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المؤلفون: Ana Reis, Helen R. Griffiths, Maria Cristina Polidori, Irundika H.K. Dias, Shaun Fell, Gregory Y.H. Lip, Jayna J. Mistry, Corinne M. Spickett
المصدر: Free Radical Biology & Medicine
مصطلحات موضوعية: Aging, BACE, β-secretase β-site amyloid cleaving enzyme, Aβ, β-amyloid, NAC, N-acetylcysteine, Free radicals, CSF, cerebrospinal fluid, Biochemistry, chemistry.chemical_compound, LDL, low-density lipoprotein, GSH, glutathione, Aspartic Acid Endopeptidases, Enzyme Inhibitors, E-64, proteinase inhibitor E-64, BBB, blood–brain barrier, Aged, 80 and over, Glutathione Disulfide, EGTA, ethylene glycol tetraacetic acid, GSSG, oxidized glutathione, Low-density lipoprotein, Desipramine, BSO, buthionine sulfoximine, BACE1, Free Radical Scavengers, Original Contribution, ELISA, enzyme-linked immunosorbent assay, ASMase, acid sphingomyelinase, Glutathione, Lipid oxidation, 3. Good health, Lipoproteins, LDL, Sphingomyelin Phosphodiesterase, Cholesterol, lipids (amino acids, peptides, and proteins), Acid sphingomyelinase, 27OH-C, 27-hydroxycholesterol, Oxidation-Reduction, OxLDL, medicine.drug, medicine.medical_specialty, PVDF, polyvinylidene fluoride, Cell Survival, PBST, phosphate-buffered saline with 1% Tween 20, Membrane lipids, PBS, phosphate-buffered saline, EDTA, ethylenediamine tetraacetic acid, Redox, Membrane Microdomains, Alzheimer Disease, APP, amyloid precursor protein, Internal medicine, Cell Line, Tumor, Physiology (medical), medicine, BHT, butylated hydroxytoluene, GSH, Humans, SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis, Aged, MDA, malondialdehyde, Amyloid beta-Peptides, SM, sphingomyelin, AD, Alzheimer disease, GCL, glutamate–cysteinyl ligase, Lipid metabolism, Cholesterol, LDL, ESI–MS, electrospray ionization mass spectrometry, Lipid Metabolism, Hydroxycholesterols, BCA, bicinchoninic acid, Acetylcysteine, Enzyme Activation, CTB, cholera toxin B, Lipid raft, Endocrinology, chemistry, oxLDL, oxidized low-density lipoprotein, Amyloid Precursor Protein Secretases, Lipoprotein
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المؤلفون: Gerrit Herrman, Walter Miklos, Ute Jungwirth, Bernhard K. Keppler, Walter Berger, Christian R. Kowol, Petra Heffeter, Christine Pirker, R. Dornetshuber, Gunda Koellensperger
المصدر: Biochemical Pharmacology
مصطلحات موضوعية: TD, terminal dimethylation, BCRP, breast cancer resistance protein, Cell, Resistance, KP1719, [bis(3-aminopyridine-2-carboxaldehyde 4,4-dimethylthiosemicarbazonato-N,N,S)gallium(III)] hexafluorophosphate, ATP-binding cassette transporter, DMSO, dimethyl sulfoxide, Multidrug resistance, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, MRP, multidrug resistance-related protein, MDR, multidrug resistance, Heterocyclic Compounds, P-gp, P-glycoprotein, GSH, glutathione, ATP Binding Cassette Transporter, Subfamily G, Member 2, In Situ Hybridization, Fluorescence, 0303 health sciences, Comparative Genomic Hybridization, biology, ABC, ATP-binding cassette, CSA, cyclosporin A, Glutathione, 3. Good health, Neoplasm Proteins, CDNB, 1-chloro-2,4-dinitrobenzene, medicine.anatomical_structure, 030220 oncology & carcinogenesis, KP1657, [bis(2-acetylpyridine thiosemicarbazonato-N,N,S)gallium(III)] nitrate, ABCC1, DMF, dimethylformamide, ABC transporter, Multidrug Resistance-Associated Proteins, KP1089, [bis(2-acetylpyridine 4,4-dimethylthiosemicarbazonato-N,N,S)gallium(III)] tetrachloridogallate, Lead compound, Thiosemicarbazones, Stereochemistry, LRP, lung resistance protein, Blotting, Western, PBS, phosphate-buffered saline, Antineoplastic Agents, KP1550, 2-acetylpyridine 4,4-dimethylthiosemicarbazone, Methylation, Article, 03 medical and health sciences, Cell Line, Tumor, GST, glutathione-S-transferase, medicine, Humans, ESI-MS, electrospray ionization mass spectrometry, Semicarbazone, Triapine, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, KP1740, [bis(2-formylpyridine 4,4-dimethylthiosemicarbazonato-N,N,S)gallium(III)] hexafluorophosphate, Multiple drug resistance, chemistry, Cell culture, Drug Resistance, Neoplasm, biology.protein, BSA, bovine serum albumin, ATP-Binding Cassette Transporters, Triapine
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المؤلفون: Pak Ho Chan, Pui Kin So, Wai Hong Chung, Ming‑San Tsang, Yun Chung Leung, Wing Lam Cheong
المصدر: Bioscience Reports
Bioscience Reports, Vol 34, Iss 5, p e00136 (2014)مصطلحات موضوعية: Fluorophore, Mutant, lcsh:Life, lcsh:QR1-502, Biophysics, Drug Evaluation, Preclinical, Mutation, Missense, TIPP, tetraiodophenolphthalein, Biosensing Techniques, beta-Lactams, Biochemistry, lcsh:Microbiology, beta-Lactamases, antibiotics, IRT, inhibitor-resistant TEM, chemistry.chemical_compound, Residue (chemistry), sensor, Catalytic Domain, inhibitors, Escherichia coli, BAEE, Nc-benozyl-L-arginine ethyl ester, drug screening, Fluorescein, bacteria, TEM, transmission electron microscopy, Molecular Biology, Original Paper, biology, Escherichia coli Proteins, Wild type, Active site, Cell Biology, ESI–MS, electrospray ionization mass spectrometry, β-lactamase, Small molecule, Fluorescence, lcsh:QH501-531, chemistry, Amino Acid Substitution, ES*, covalent enzyme-substrate, ESBL, extended spectrum β-lactamase, biology.protein, ES, enzyme-substrate
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19Academic Journal
المؤلفون: Zare, Richard N
المساهمون: LELAND STANFORD JUNIOR UNIV CA
المصدر: DTIC
مصطلحات موضوعية: Nuclear Physics & Elementary Particle Physics, Mechanics, KINETICS, MASS SPECTROMETRY, FLOW, FRAGMENTATION, IONIZATION, PRECIPITATES, HADAMARD TRANSFORM MASS SPECTROMETRY, ESI-MS(ELECTROSPRAY IONIZATION MASS SPECTROMETRY), DESI(DESORPTION ELECTROSPRAY IONIZATION), STOPPED-FLOW
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20Dissertation/ Thesis
المؤلفون: Odoi, Keturah
Thesis Advisors: Liu, Wenshe
مصطلحات موضوعية: Pyl, pyrrolysine, PylRS, pyrrolysyl-tRNA synthetase, NAA, noncanonical amino acid, BocK, Ntert-butyloxycarbonyl)-L-lysine, aaRS, aminoacyl-tRNA synthetase, MjTyrRS, Methanococcus jannaschii tyrosyl-tRNA synthetase, T4 PNK, T4 polynucleotide kinase, AzF, para-azido-L-phenylalanine, ESI-MS, electrospray ionization mass spectrometry, PCR, polymerase chain reaction, sfGFP, superfolder green fluorescent protein, sfGFP134TAG, the sfGFP gene with an amber mutation at N134 and a 6×His tag at its C-terminus, sfGFP134TGA,the sfGFP gene with an opal mutation at N134 and a 6×His tag at its C-terminus, sfGFP134TAA,the sfGFP gene with an ochre mutation at N134 and a 6×His tag at its C-terminus, sfGFP134AGGA,the sfGFP gene with an quadruple AGGA mutation at N134 and a 6×His tag at its C-terminus, sfGFP2TAG134TAA, the sfGFP gene with an amber mutation at S2, an ochre mutation at N134, and a 6×His tag at its C-terminus, sfGFP2TGA, the sfGFP gene with an opal mutation at S2 and a 6×His tag at its C-terminus, IPTG, isopropyl -D-thiogalactopyranoside, RF, release factor, TrpRS, tryptophanyl-tRNA synthetase, ArgRS, arginyl-tRNA synthetase, Trp, tryptophan, Lys, lysine, Glu, glutamate, Gln, glutamine, Phe, phenylalanine, Arg, arginine.
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