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المؤلفون: Hoda Safari Yazd, Sina Feizbakhsh Bazargani, Christine A. Vanbeek, Kelli King-Morris, Coy Heldermon, Mark S. Segal, Richard Yost, William L. Clapp, Timothy J. Garrett
المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 22, Iss, Pp 71-78 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Labمصطلحات موضوعية: medicine.medical_specialty, Pathology, CAN, Acetonitrile, MS/MS, Tandem Mass Spectrometry, OCT, Optimal Cutting Temperature, CDH, Cerebrodihexoside, LC/MS, Liquid Chromatography-Mass Spectrometry, UHPLC-HRMS, Ultra-High Pressure Liquid Chromatography-High-Resolution Mass Spectrometry, Clinical Biochemistry, Globotriaosylceramide, Cnvs, Copy Number Variants, Microbiology, Special issue on Lipidomics, chemistry.chemical_compound, ERT, Enzyme Replacement Therapy, Liquid chromatography–mass spectrometry, Ga2, Galabiosylceramide, Biopsy, Lipidomics, Medical technology, medicine, R855-855.5, GLA, Glactosidase Alpha, SRM, Selected Reaction Monitoring, Spectroscopy, EIC, Extracted Ion Chromatogram, ND, Not Detected, Kidney, Clinical pathology, medicine.diagnostic_test, business.industry, Gb3, Globotriaosylceramide, SECIM, Southeast Center for Integrated Metabolomics, medicine.disease, Fabry disease, Chcl3, Chloroform, α-GAL A, α-Galactosidase A, Lyso-Gb3, Globotriaosylsphingosine, Medical Laboratory Technology, medicine.anatomical_structure, chemistry, IPA, 2-Propanol, Renal biopsy, Meoh, Methanol, business, LSD, Lysosomal Storage Disorder
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المؤلفون: Sten Ohlson, Minh-Dao Duong-Thi, Anandalakshmi Venkatraman, Konstantin Pervushin, Jodhbir S. Mehta
المساهمون: School of Biological Sciences
المصدر: Journal of Advanced Research, Vol 24, Iss, Pp 529-543 (2020)
Journal of Advanced Researchمصطلحات موضوعية: 0301 basic medicine, HPLC, High-performance liquid chromatography, Mutant, Corneal dystrophy, Peptide, 1D, 1-Dimensional, ITC, Isothermal Titration Calorimetry, Protein aggregation, LE, Ligand Efficiency, 0302 clinical medicine, TGFBIp, Transforming Growth Factor Beta Induced protein, Mutant protein, DSS, 4, 4-dimethyl-4-silapentane-1-sulfonic acid, MS, Mass spectrometry/spectrometer, GCD, Granular Corneal Dystrophy, chemistry.chemical_classification, EIC, Extracted Ion Chromatogram, lcsh:R5-920, Multidisciplinary, biology, medicine.diagnostic_test, Biological sciences [Science], SD, Standard Deviation, BMRB, Biological Magnetic Resonance Data Bank, Cell biology, FAS1, Fasciclin like Domain, 030220 oncology & carcinogenesis, ms, Millisecond, WAC, Weak affinity chromatography, 2D, 2-Dimensional, HSQC, Heteronuclear Single Quantum Coherence Spectroscopy, lcsh:Medicine (General), TFA, Trifluoroacetic acid, PBS, Phosphate Buffered Saline, Weak Affinity Chromatography, SPR, Surface Plasmon Resonance, Proteolysis, Fragment screening, Corneal Dystrophy, TGFBIp, TGFBI, Transforming Growth Factor Beta Induced, Article, 03 medical and health sciences, Weak affinity chromatography, medicine, EMI, Emilin-like domain, IPTG, Isopropyl-beta-D-thiogalactopyranoside, lcsh:Science (General), ComputingMethodologies_COMPUTERGRAPHICS, AA, Amino Acid, FPLC, Fast Protein Liquid Chromatography, LB, Luria Bertani, TOF, Time-of-Flight, 3D, 3-Dimensional, MALDI, Matrix-Assisted Laser Desorption/Ionization, DMSO, Dimethyl sulfoxide, Transforming growth factor beta, WT, Wild Type, medicine.disease, SDS-PAGE, Sodium Dodecyl Sulphate-polyacrylamide gel electrophoresis, eye diseases, 030104 developmental biology, chemistry, biology.protein, LCD, Lattice Corneal Dystrophy, TGFBI, lcsh:Q1-390
وصف الملف: application/pdf
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المؤلفون: Pratibha P, Ghodke, Jyotirling R, Mali, Amritraj, Patra, Carmelo J, Rizzo, F Peter, Guengerich, Martin, Egli
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: dNMPnPP, 2′-deoxynucleoside-5′-[(α,β)-imido]triphosphate, CID, collision-induced dissociation, 1,N2-ε-G, 1,N2-ethenodeoxyguanosine or 1,N2-ethenoguanine, DNA-Directed DNA Polymerase, DNA polymerase, DNA replication, dCMPnPP, 2′-deoxycytosine-5′-[(α,β)-imido]triphosphate, Crystallography, X-Ray, UPLC, ultraperformance liquid chromatography, DNA Adducts, h, human, Tandem Mass Spectrometry, Humans, translesion synthesis, X-ray crystallography, mass spectrometry, ESI, electrospray ionization, Deoxyguanosine, EIC, extracted ion chromatogram, UDG, uracil DNA glycosylase, DNA damage, dAMPnPP, 2′-deoxyadenosine-5′-[(α,β)-imido]triphosphate, pol, DNA polymerase, DNA–protein interaction, FAM, 6-carboxyfluorescein, Chromatography, Liquid, Research Article, etheno DNA adducts
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المؤلفون: Aleksandra Shcherbakova, Karsten Cirksena, Joachim Wittbrodt, Falk F. R. Buettner, Roman Sakson, Lars R. Jensen, Thomas Ruppert, Daniel Todt, Andreas W. Kuss, Alina Friedrich, Stefan Weiss, Hermann J. Hütte, Hans Bakker, Thomas Thumberger
المصدر: Molecular & Cellular Proteomics : MCP
مصطلحات موضوعية: RT, retention time, TSR, thrombospondin type 1 repeat, Oryzias, LTQ, Linear Trap Quadrupole, CBiPSC2, human cord blood–derived induced pluripotent stem cell clone 2, Eye, Biochemistry, Mannosyltransferases, Analytical Chemistry, ADAMTS Proteins, hiPSC, human induced pluripotent stem cell, Zebrafish, secretomics, FA, formic acid, Gene Editing, 0303 health sciences, Metalloproteinase, ESI, electrospray ionization, 030302 biochemistry & molecular biology, ADAMTS16, RI, ROCK inhibitor, Cell biology, Mannosylation, Gene Knockdown Techniques, coloboma, THBS1, thrombospondin 1, sgRNA, single-guide RNA, Induced Pluripotent Stem Cells, Biology, CHO, Chinese hamster ovary, Cell Line, TFA, trifluoroacetic acid, 03 medical and health sciences, HEK, human embryonic kidney, Cricetulus, C-mannosylation, Thrombospondin 1, Animals, Humans, Secretion, eGFP, enhanced GFP, Molecular Biology, 030304 developmental biology, Thrombospondin, Research, HEK 293 cells, LFQ, label-free quantification, ACN, acetonitrile, biology.organism_classification, EIC, extracted ion chromatogram, carbohydrates (lipids), human induced pluripotent stem cells, Eye development, FCS, fetal calf serum, Mannose, MRM, multiple reaction monitoring
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المؤلفون: Alexander Titz, Qingping Xu, Marina Borisova, Alicia Engelbrecht, Isabel Hottmann, Christoph Mayer, Maraike Müller, Matthew B. Calvert, Robert Maria Kluj, Khaled A. Selim, Tim Teufel, Katja Balbuchta
المساهمون: HIPS, Helmholtz-Institut für Pharmazeutische Forschung Saarland, Universitätscampus E8.1 66123 Saarbrücken, Germany.
المصدر: The Journal of Biological Chemistry
The Journal of biological chemistry
United Statesمصطلحات موضوعية: 0301 basic medicine, CAZy, Protein family, Glycoside Hydrolases, peptidoglycan hydrolase, Protein Conformation, pNP-GlcNAc, para-nitrophenyl 2-acetamido-2-deoxy-β-d-glucopyranoside, Bacillus subtilis, Peptidoglycan, cell wall recycling, AUC, area under curve, Crystallography, X-Ray, Biochemistry, N-acetylmuramidase, Acetylglucosamine, 03 medical and health sciences, chemistry.chemical_compound, N-Acetylglucosamine, Molecular Biology, lysozyme, BPC, base peak chromatogram, exo-lytic glycosidase, 030102 biochemistry & molecular biology, biology, Chemistry, Hydrolysis, pNP-MurNAc, para-nitrophenyl 2-acetamido-3-O-(d-1-carboxyethyl)-2-deoxy-β-D-glucopyranoside, Cell Biology, GlcNAc, N-acetylglucosamine, biology.organism_classification, Rossmann-fold, Hexosaminidases, EIC, extracted ion chromatogram, carbohydrates (lipids), 030104 developmental biology, N-Acetylmuramic acid, Muramic Acids, N-acetylglucosaminidase, Lysozyme, MurNAc, N-acetylmuramic acid, Research Article, N-acetylmuramoyl amidase
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المصدر: Molecular & Cellular Proteomics : MCP
مصطلحات موضوعية: bottom–up proteomics, DIA, data-independent acquisition, Peptide, DMSO, dimethyl sulfoxide, Biochemistry, Analytical Chemistry, trimethylacetic anhydride, Histones, chemistry.chemical_compound, Mice, Tandem Mass Spectrometry, PRM, parallel reaction monitoring, HDACi, histone deacetylase inhibitor, chemistry.chemical_classification, 0303 health sciences, TMA, trimethylacetic anhydride, biology, Chemistry, 030302 biochemistry & molecular biology, Histone deacetylase inhibitor, Technological Innovation and Resources, Acetylation, Histone, histone post-translational modifications, Amine gas treating, Bottom-up proteomics, medicine.drug_class, Acetic Anhydrides, Enti, entinostat, TFA, trifluoroacetic acid, 03 medical and health sciences, hPTM, histone post-translational modification, Propionic anhydride, Cell Line, Tumor, medicine, Trifluoroacetic acid, Animals, Derivatization, Molecular Biology, microwave irradiation, 030304 developmental biology, Chromatography, ACN, acetonitrile, EIC, extracted ion chromatogram, Prop, propionic anhydride, biology.protein, DDA, data-dependent acquisition, chemical derivatization, Protein Processing, Post-Translational, Chromatography, Liquid
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المؤلفون: Rebeca Kawahara, Fabian Soltermann, Hannes Hinneburg, Siyun Chen, Robert J. Woods, Regis Dieckmann, Morten Thaysen-Andersen, Ian Loke, Vignesh Venkatakrishnan, Weston B. Struwe, Oliver C. Grant, Alison Rodger, Julian Ugonotti, Harry C. Tjondro, Johan Bylund, Benjamin L. Parker, Anna Karlsson-Bengtsson, Sayantani Chatterjee
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, Glycosylation, Az-MPO, azurophilic granule-resident MPO, Neutrophils, GlcNAc, N-acetyl-β-D-glucosamine, HOCl, hypochlorous acid, MPO, myeloperoxidase, N-glycosylation, Biochemistry, SN, maturing neutrophil with segmented nuclei, chemistry.chemical_compound, N-linked glycosylation, Sp granule, specific granule, PMN-nMPO, myeloperoxidase from derived from resting (circulating) neutrophils, Sp-MPO, specific granule-resident MPO, Se/Pl-MPO, secretory vesicle/plasma membrane-resident MPO, CD, circular dichroism, Se/Pl, secretory vesicle and plasma membrane fraction, PMN, polymorphonuclear cell (neutrophil), biology, granulopoiesis, LDH, lactate dehydrogenase, LFQ, label-free quantitation, Glycopeptides, neutrophil, RMSF, root mean squared fluctuation, Editors' Pick, MD, molecular dynamics, inhibition, Cell biology, ceruloplasmin, myeloperoxidase, BN, band neutrophil, Man, α/β-D-mannose, Myeloperoxidase, H2O2, hydrogen peroxide, PGC, porous graphitised carbon, nMPO, neutrophil-derived myeloperoxidase (unfractionated), Research Article, Glycan, Endo H, endoglycosidase H, TMB, 3,3ʹ,5,5ʹ-tetramethylbenzidine, Ge-MPO, gelatinase granule-resident MPO, Cytoplasmic Granules, Granulopoiesis, ER, endoplasmic reticulum, MOI, multiplicity-of-infection, 03 medical and health sciences, Azurophilic granule, Endoglycosidase H, Polysaccharides, PDB, Protein Data Bank, Humans, RMSD, root mean squared deviation, KRG buffer, Krebs-Ringer buffer with glucose, Molecular Biology, Az granule, azurophilic granule, Dg-MPO, degranulated MPO, Peroxidase, PM, promyelocyte, degranulation, 030102 biochemistry & molecular biology, activity, LC-MS/MS, liquid chromatography tandem mass spectrometry, MM, metamyelocyte, Cell Biology, granule, Fuc (F), α-L-fucose, EIC, extracted ion chromatogram, CytB/I, cytochalasin B and ionomycin, 030104 developmental biology, Specific granule, chemistry, biology.protein, AUC, area-under-the-curve, biosynthesis, SD, standard deviation, Ge granule, gelatinase granule
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المؤلفون: Christoph Peschel, Fabian Horsthemke, Martin Winter, Sascha Nowak
المصدر: MethodsX
MethodsX, Vol 9, Iss, Pp 101621-(2022)مصطلحات موضوعية: Science, GC-HRMS, Clinical Biochemistry, EI, electron ionization, Target analysis, BMC, n-butyl methyl carbonate, sBEC, sec-butyl ethyl carbonate, Method Article, LIB, lithium ion battery, Orbitrap mass spectrometry, EPC, ethyl propyl carbonate, BEC, n-butyl ethyl carbonate, MPC, methyl propyl carbonate, SQ, single quadrupole, Lithium ion battery electrolytes, EIC, extracted ion chromatogram, Target analysis via GC-HRMS of lithium ion battery electrolyte decomposition, HRMS, high resolution mass spectrometry, Medical Laboratory Technology, GC-MS, gas chromatography – mass spectrometry, FWHM, full width at half maximum, sBMC, sec-butyl methyl carbonate, SPME, solid phase microextraction
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المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Glycosylation, EGF-like domain, Fibrillin-2, Fibrillin-1, Amino Acid Motifs, glycoprotein secretion, IgG, immunoglobulin G, PBS, phosphate-buffered saline, PEI, polethylenimine, LTBP1, latent transforming growth factor β-binding protein 1, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, Marfan Syndrome, MEM, minimal essential medium, protein folding, Humans, Secretion, EGF repeats, Molecular Biology, ANOVA, analysis of variance, mass spectrometry, TGF-β, transforming growth factor β, Chemistry, HEK 293 cells, Wild type, extracellular matrix protein, Cell Biology, HEK293T, human embryonic kidney 293T, ECM, extracellular matrix, EIC, extracted ion chromatogram, Cell biology, TBS, Tris-buffered saline, Latent TGF-beta Binding Proteins, Notch proteins, O-glucose, FBN2, fibrillin-2, Protein Translocation Systems, EGF, epidermal growth factor-like, Protein folding, FBN1, fibrillin-1, MFS, Marfan syndrome, SD, standard deviation, Fibrillin, POGLUT2, protein O-glucosyltransferase 2, Research Article, POGLUT3, protein O-glucosyltransferase 3, Signal Transduction
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المؤلفون: Bert Chi, Andrew Patron, Michael Saganich, Sara Werner, Catherine Tachdjian, Guy Servant, Amy J. Arthur, Joseph R. Fotsing, Lily Ida, Hanghui Liu, Donald S. Karanewsky
المصدر: Toxicology Reports, Vol 4, Iss, Pp 507-520 (2017)
Toxicology Reportsمصطلحات موضوعية: 0301 basic medicine, CL, plasma clearance, Health, Toxicology and Mutagenesis, S2218, Pharmacology, Toxicology, LC/MS, liquid chromatography with mass spectrometry, AUC, area under the curve, t1/2, half-life, Ingredient, MC, methylcellulose, Genetic toxicological evaluation, GLP, Good Laboratory Practices, TK, toxicokinetics, Flavours with modifying properties, Chemistry, FL-no, FLAVIS number, 04 agricultural and veterinary sciences, 040401 food science, Micronucleus test, amu, atomic mass units, CYP, cytochrome P450, Gestation, CBPI, cytokinesis-blocked proliferation index, Tmax, time to reach Cmax, FEMA GRAS, 03 medical and health sciences, Clastogen, 0404 agricultural biotechnology, stomatognathic system, Pharmacokinetics, lcsh:RA1190-1270, Full Length Article, Vss, volume of distribution at steady-state, FMP, flavour with modifying properties, Developmental toxicity evaluation, OECD, Organization for Economic Cooperation and Development, lcsh:Toxicology. Poisons, Fetus, GMP, Good Manufacturing Practices, Subchronic toxicological evaluation, NOAEL, no-observed-adverse-effect-level, FEMA, Flavour and Extract Manufacturers Association of the United States, FDA, Food and Drug Administration, In vitro, EIC, extracted ion chromatogram, Bioavailability, 030104 developmental biology, HPBL, human peripheral blood lymphocytes, PK, pharmacokinetics, Cmax, peak plasma concentration
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المؤلفون: Suresh Venkateswaran, Nicholas Siano, Jill M. Weimer, Nickita Mehta, Renee Krampetz, Nithya Selvan, Hung V. Do, Jon Brudvig, Yuliya McAnany, Finn Hung, Anuj Mehta, Matthew Graziano, Matthew Madrid, Russell Gotschall, M. Osman Sheikh, Nastry Brignol
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, PNGase F, MWCO, molecular weight cutoff, TBS, tris buffered saline, Biochemistry, MW, molecular weight, Lysosomal storage disease, Glycogen storage disease, AOAA, aminooxyacetic acid, lysosomal glycoprotein, medicine.diagnostic_test, biology, Glycogen Storage Disease Type II, Chemistry, Hydrolysis, GAA, acid alpha-glucosidase, Glycopeptides, Enzyme replacement therapy, ERT, enzyme replacement therapy, lysosomal storage disease, lysosome, kif, kifunensine, LSD, least significant difference, Acid alpha-glucosidase, HPAEC-PAD, high-pH anion-exchange chromatography with pulsed amperometric detection, Glycogen, Research Article, Glycan, Proteolysis, WGA, wheat germ agglutinin, Endosomes, CHO, Chinese hamster ovary, mannose 6-phosphate, HCD MS2, higher-energy collisional dissociation MS2, 03 medical and health sciences, N-glycan processing, glycogen storage disease, FBS, fetal bovine serum, Polysaccharides, medicine, Humans, rhGAA, recombinant human GAA, Molecular Biology, 030102 biochemistry & molecular biology, M6P, mannose 6-phosphate, Endo H, Endoglycosidase H, alpha-Glucosidases, Cell Biology, enzyme processing, medicine.disease, CI-MPR, cation-independent M6P receptor, EIC, extracted ion chromatogram, 030104 developmental biology, biology.protein, BSA, bovine serum albumin, PNGase F, peptide:N-glycanase F
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المؤلفون: Miyako Nakano, Eiji Miyoshi, Masato Kitano, Kazuki Nakajima, Yoichiro Harada, Saki Itoyama, Yasuhiko Kizuka, Tomoaki Sobajima, Akihiro Harada, Ryo Misaki, Naoyuki Taniguchi
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, sialyltransferase, Glycosylation, RCA120, Ricinus Communis Agglutinin 120, SDS-PAGE, SDS-polyacrylamide gel electrophoresis, Golgi Apparatus, DKD cells, HeLa cells in which both Rab11a and Rab11b are stably knocked down, NeuAc, CMP-N-acetylneuraminic acid, vWF, von Willebrand factor, glycosyltransferase, B4GALNT2, beta-1,4-N-acetylgalactosaminyltransferase 2, Biochemistry, ConA, concanavalin A lectin, B4GALT1, beta-1,4-galactosyltransferase 1, chemistry.chemical_compound, ManNAz, N-azidoacetylmannosamine, N-linked glycosylation, ST8SIA1, Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase, TBS, tris-buffered saline, IKO, intestine-specific Rab11a knockout, PhoSL, Pholiota squarrosa lectin, LC-ESI-MS, liquid chromatography–electrospray ionization–mass spectrometry, FUT8, fucosyltransferase 8, chemistry.chemical_classification, glycan, Gene knockdown, biology, Chemistry, PNGase F, peptide N-glycosidase F, Editors' Pick, SiaNAz, N-azidoacetyl sialic acid, Cell biology, Protein Transport, PM, plasma membrane, symbols, trans-Golgi Network, Research Article, Endo H, endoglycosidase H, Endosome, membrane traffic, α2,3-sialylation, ER, endoplasmic reticulum, 03 medical and health sciences, Endoglycosidase H, symbols.namesake, CHX, cycloheximide, sLeX, sialyl-LewisX, MAM, Maackia amurensis lectin, ST6GAL1, Beta-galactoside alpha-2,6-sialyltransferase 1, Animals, Humans, COG, conserved oligomeric Golgi, ST3GAL4, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4, Molecular Biology, PGC, post-Golgi compartment, posttranslational modification, 030102 biochemistry & molecular biology, TGN, trans-Golgi network, Endoplasmic reticulum, Cell Biology, Golgi apparatus, L4-PHA, Phaseolus vulgaris Leucoagglutinin lectin, Sialyltransferases, Rats, EIC, extracted ion chromatogram, carbohydrates (lipids), 030104 developmental biology, rab GTP-Binding Proteins, Rab11, ST3GAL4, GlcAT-P, glucuronyltransferase-P, PVDF, poly(vinylidene fluoride), SSA, Sambucus sieboldiana lectin, biology.protein, Glycoprotein, HeLa Cells
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المؤلفون: Steven Y. Qian, Yi Xu, Xiaoyu Yang, Jin Qi, Erxi Wu
المصدر: Redox Biology
Redox Biology, Vol 2, Iss C, Pp 610-618 (2014)مصطلحات موضوعية: Clinical Biochemistry, DHA, docosahexaenoic acid, AA, arachidonic acid, Apoptosis, 8-HOA, 8-hydroxyoctanoic acid, Pharmacology, COX-catalyzed PUFA peroxidation, Biochemistry, Lipid peroxidation, chemistry.chemical_compound, 8,11,14-Eicosatrienoic Acid, 5-FU, 5-Fluorouracil, HPLC/LC, high performance liquid chromatography, Cell cycle and apoptosis, lcsh:QH301-705.5, D5D, delta-5 desaturase, chemistry.chemical_classification, lcsh:R5-920, biology, Cell Cycle, Combination chemotherapy, HEX, 1-hexanol, TBS, Tris buffered saline, PGs, prostaglandins, 3. Good health, SPE, solid phase extraction, Colonic Neoplasms, ESR, electron spin resonance, Arachidonic acid, HTA, heptanoic acid, Fluorouracil, lcsh:Medicine (General), GC, gas chromatography, Colon cancer cell line HCA-7 colony 29, Polyunsaturated fatty acid, Free Radicals, 5-Fluorouracil, Antineoplastic Agents, Article, PI, propidium iodide, Structure-Activity Relationship, TIC, total ion chromatogram, Cell Line, Tumor, PUFA, polyunsaturated fatty acid, Humans, POBN, α-[4-pyridyl-1-oxide]-N-tert-butyl nitrone, Cell Proliferation, Dihomo-γ-linolenic acid, Dose-Response Relationship, Drug, Cell growth, Organic Chemistry, Fatty acid, LC/MS and ESR spin trapping, ACN, acetonitrile, EPA, eicosapentaenoic acid, EIC, extracted ion chromatogram, COX, cyclooxygenase, lcsh:Biology (General), chemistry, MS, mass spectrometry, DGLA׳s free radical derivatives, DGLA, dihomo-γ-linoleic acid, Prostaglandin-Endoperoxide Synthases, biology.protein, HOAc, glacial acetic acid, Biocatalysis, Cyclooxygenase, Lipid Peroxidation, Drug Screening Assays, Antitumor
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المؤلفون: Tommaso Trenti, Cristina Rota, Elisabetta Cariani, Simone Cristoni
المصدر: Redox Biology
Redox Biology, Vol 1, Iss 1, Pp 492-497 (2013)مصطلحات موضوعية: Male, NER, nucleotide excision repair system, Clinical Biochemistry, Urine, Tandem mass spectrometry, Biochemistry, chemistry.chemical_compound, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, 8-oxo-7,8-dihydro-2′-deoxyguanosine, Deoxyguanosine, IS, internal standard, lcsh:QH301-705.5, LOQ, limit of quantitation, lcsh:R5-920, EIC, Extracted Ion Chromatogram, 8-oxodG, 8-oxo-7, 8-dihydro-2′-deoxyguanosine, ESI, electrospray ionization, Middle Aged, 8-Hydroxy-2'-Deoxyguanosine, MTH1, Nudix hydrolase mut T homologue 1, Creatinine, Female, Ion trap, lcsh:Medicine (General), Research Paper, Adult, NIR, nucleotide incision repair system, Ion, ROS, reactive oxygen species, Cations, Humans, LC-MS/MS, Detection limit, 15[N5]8-oxodG, 8-oxo-7, 8-dihydro-15[N5]2′-deoxyguanosine, Chromatography, IQC, internal quality control, LC-MS/MS, liquid chromatography tandem mass spectrometry, Organic Chemistry, Reproducibility of Results, SACI, surface-activated ionization, TIC, Total Ion Chromatogram, lcsh:Biology (General), 15[N5]2-dG, 15[N5]2′-deoxyguanosine, chemistry, Oxidative stress, Reactive oxygen species, MRM, multiple reaction monitoring, Chromatography, Liquid