يعرض 1 - 20 نتائج من 365 نتيجة بحث عن '"EGF epidermal growth factor"', وقت الاستعلام: 0.62s تنقيح النتائج
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    Academic Journal
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    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 843-856 (2022)
    Cellular and Molecular Gastroenterology and Hepatology

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    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 517-540 (2022)
    Cellular and Molecular Gastroenterology and Hepatology

    مصطلحات موضوعية: Colorectal cancer, EdU, 5-ethynyl-2’-deoxyuridine, RNP, ribonucleoprotein, Cetuximab, RC799-869, DMSO, dimethyl sulfoxide, medicine.disease_cause, MEK, mitogen-activated protein/extracellular signal-regulated kinase kinase, eKRAS, clustered regularly interspaced short palindromic repeats/Cas9-generated KRASG12D, PDTO, patient-derived tumor organoid, PCR, polymerase chain reaction, ERK, extracellular signal-regulated kinase, GSEA, gene set enrichment analysis, IC50, half-maximal inhibitory concentration, CT-PDTO, chemotherapy-adapted patient-derived tumor organoid, 5’-FU, 5-fluorouracil, Medicine, E2F1, Epidermal growth factor receptor, ANOVA, analysis of variance, Original Research, Aurora Kinase A, biology, TOC, tumor organoid culture, Liver Neoplasms, Gastroenterology, AfaSel, afatinib + selumetinib, FOLFIRI, folinic acid, Combination chemotherapy, Diseases of the digestive system. Gastroenterology, ADF, advanced Dulbecco’s modified Eagle medium/F12, FFPE, formalin-fixed paraffin-embedded, Organoids, CRISPR, clustered regularly interspaced short palindromic repeats, CRC, colorectal cancer, FOLFIRI, Cas9, CRISPR-associated 9 protein, 5’-FU, irinotecan (or SN-38), KRAS, Colorectal Neoplasms, SN-38, irinotecan active metabolite, Chemoresistance, medicine.drug, AURKA, Aurora kinase A, CRC Organoid, c-MYC, c-MYC oncogene, cDNA, complementary DNA, Cmab, cetuximab, E2F, E2 transcription factor, RAS, rat sarcoma viral oncogene homolog, 3D, 3-dimensional, Humans, MSI, microsatellite instable, UMI, unique molecular identifier, EGF, epidermal growth factor, HER, human epithelial growth factor receptor, Hepatology, business.industry, PARP, poly-adenosine diphosphate ribose polymerase, LMU, Ludwig-Maximilians-University, medicine.disease, digestive system diseases, EGFR, epidermal growth factor receptor, Cancer research, biology.protein, TCGA, The Cancer Genome Atlas, business, MAPK, mitogen-activated protein kinase

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    المؤلفون: David A. Frank, Isidora Tošić

    المصدر: Neoplasia (New York, N.Y.)
    Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)

    مصطلحات موضوعية: Cancer Research, p53, tumor protein 53, MEF2D, Myocyte Enhancer Factor 2D, FASN, fatty acid synthase, OXPHOS, oxidative phosphorylation, ERH, enhancer of rudimentary homolog, PDGF, platelet-derived growth factor, PFK, phosphofructokinase, CREB, cyclic AMP response element-binding protein, HDL-C, high-density lipoprotein cholesterol, chemistry.chemical_compound, PC, phosphatidylcholine, GRIM-19, gene associated with retinoid-IFN-induced mortality, Neoplasms, Transcriptional regulation, TGFβ, transforming growth factor beta, AML, acute myeloid leukemia, RC254-282, CDK, cyclin-dependent kinase, FABP6, fatty acid binding protein 6, BCL, B-cell lymphoma, CLL, chronic lymphocytic leukemia, Chemistry, LIF, leukemia inhibitory factor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, VEGF, vascular endothelial growth factor, FBP1, fructose-bisphosphatase 1, GPI, glucose-6-phosphate isomerase, Cell biology, MMP, matrix metalloproteinase, STAT, signal transducer and activator of transcription, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, GP130, glycoprotein 130, Phosphorylation, NHL, non-Hodgkin's lymphoma, JAK, Janus kinase, Adenosine triphosphate, CNTF, ciliary neurotrophic factor, STAT3 Transcription Factor, ATP, adenosine triphosphate, TAG, triacylglycerol, Protein processing, Post-translational, PPARγ, peroxisome proliferator-activated receptor gamma, ETC, electron transport chain, TNFα, tumor necrosis factor alpha, RIME, rapid immunoprecipitation mass spectrometry of endogenous proteins, GLUT1, glucose transporter 1, PGK1, phosphoglycerate kinase, MPTP, mitochondrial permeability transition pore, Mediator, Review article, CML, chronic myeloid leukemia, HIF1α, hypoxia inducible factor, PIAS, protein inhibitors of activated STATs, SOCS, suppressors of cytokine signaling, Animals, Humans, IFN, interferon, LDHA, lactate dehydrogenase A, Transcription factor, PKCδ, protein kinase C δ, TF, transcription factors, EGF, epidermal growth factor, SM, sphingomyelin, SREBP1, sterol regulatory element-binding protein 1, IAP, inhibitor of apoptosis, PTP, protein tyrosine phosphatases, Tyrosine phosphorylation, Lipid metabolism, BCSC, breast cancer stem cells, IL, interleukin, Metabolism, OSM, oncostatin M, Anaerobic glycolysis, NFκB, nuclear factor kappa B, TBK1, TANK-binding kinase 1, MCL, myeloid cell leukemia, LDL-C, low-density lipoprotein cholesterol, PBP, PPARγ binding protein, CPT1B, carnitine palmitoyltransferase 1B, FAO, fatty acid oxidation

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    المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1697-1707 (2021)
    Acta Pharmaceutica Sinica. B

    مصطلحات موضوعية: PSCs, pluripotent stem cells, SLC, solute carrier, BCRP, breast cancer resistance protein, Abcg2, OATP, organic anion transporting polypeptide, Review, Papp, apparent permeability coefficient, 0302 clinical medicine, P-gp, P-glycoprotein, General Pharmacology, Toxicology and Pharmaceutics, Induced pluripotent stem cell, P-glycoprotein, OCT, organic cation transporter, OCTN, carnitine/organic cation transporter, 0303 health sciences, biology, Multidrug resistance-associated protein 2, MCT, monocarboxylate transporter protein, iPSCs, induced pluripotent stem cells, Phenotype, Cell biology, medicine.anatomical_structure, 3D organoid, ER, efflux ratio, 030220 oncology & carcinogenesis, Lgr5+, leucine-rich-repeat-containing G-protein-coupled receptor 5 positive, Caco-2 cell monolayer, PMAT, plasma membrane monoamine transporter, TMDs, transmembrane domains, Drug transporter, RM1-950, TEER, transepithelial electrical resistance, 03 medical and health sciences, ASCs, adult somatic stem cells, MRP2, multidrug resistance protein 2, Organoid, medicine, DDI, drug–drug interactions, NBD, nucleotide-binding domain, 030304 developmental biology, EGF, epidermal growth factor, PEPT, peptide transporter protein, Rh123, rhodamine 123, BMP, bone morphogenetic protein, ESCs, embryonic stem cells, Small intestine, FGF, fibroblast growth factor, cMOAT, canalicular multispecific organic anion transporter, CDF, 5(6)-carboxy-2′,7′-dichlorofluorescein, Cell culture, biology.protein, Therapeutics. Pharmacology

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    المصدر: Journal of Ginseng Research
    Journal of Ginseng Research, Vol 45, Iss 3, Pp 401-407 (2021)

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    المصدر: Acta Pharmaceutica Sinica. B
    Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)

    مصطلحات موضوعية: BCL-2, B cell lymphoma 2, G protein coupled receptor kinase 2, HH, Carcinogenesis, Hedgehog, HIF-1α, MDSCs, myeloid-derived suppressor cells, STAT3, signal transducer and activator of transcription 3, FOLFOX, oxaliplatin, Review, medicine.disease_cause, SMO, Smoothened, Immune tolerance, 0302 clinical medicine, βArr2, β-arrestin2, ATO, arsenic trioxide, hypoxia-inducible factor 1α, IFN-γ: interferon-γ, Medicine, General Pharmacology, Toxicology and Pharmaceutics, TGF-β, transforming growth factor β, 0303 health sciences, glioma-associated oncogene homologue, GRK2, Cancer stem cells, 5-Fu, 5-fluorouracil, TME, tumor microenvironment, IHH, Indian Hedgehog, VEGF, vascular endothelial growth factor, SHH, Sonic Hedgehog, Hedgehog signaling pathway, PD-L1, programmed cell death ligand-1, Tumor microenvironment, 030220 oncology & carcinogenesis, BMI-1, B cell-specific moloney murine leukemia virus insertion region-1, SUFU, Suppressor of Fused, Signal transduction, DHH, Desert Hedgehog, NK, natural killer, CSCs, cancer stem cells, and leucovorin, GLI, NOX4, NADPH Oxidase 4, ALK5, TGF-β receptor I kinase, PTCH, Patched, SNF5, sucrose non-fermenting 5, Gastrointestinal cancer, 03 medical and health sciences, ROS, reactive oxygen species, Immune system, Cancer stem cell, BCC, basal cell carcinoma, 030304 developmental biology, EGF, epidermal growth factor, IL-10/6, interleukin 10/6, ITCH, itchy E3 ubiquitin ligase, ch5E1, chimeric monoclonal antibody 5E1, business.industry, lcsh:RM1-950, WNT, Wingless/Integrated, PD-1, programmed cell death-1, SMAD3, mothers against decapentaplegic homolog 3, medicine.disease, lcsh:Therapeutics. Pharmacology, Drug resistance, Cancer research, PKA, protein kinase A, TAMs, tumor-related macrophages, sense organs, business, Hedgehog, CAFs, cancer-associated fibroblasts

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    المصدر: Regenerative Therapy
    Regenerative Therapy, Vol 16, Iss, Pp 1-11 (2021)

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    المصدر: Saudi Pharmaceutical Journal, Vol 29, Iss 1, Pp 12-26 (2021)
    Saudi Pharmaceutical Journal : SPJ

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    المساهمون: Gastroenterology & Hepatology, Surgery

    المصدر: Cellular and Molecular Gastroenterology and Hepatology
    Cellular and Molecular Gastroenterology and Hepatology, 11(2), 407-431. Elsevier Inc.

    مصطلحات موضوعية: FAP, fibroblast-associated protein, 0301 basic medicine, IGF, insulin-like growth factor, Liver Tumor Organoids, Wnt, wingless-related integration site, Cell–Cell Contact, Mice, PCR, polymerase chain reaction, Liver Neoplasms, Experimental, 0302 clinical medicine, Cancer-Associated Fibroblasts, Tumor Cells, Cultured, Tumor Microenvironment, Diethylnitrosamine, Paracrine Effect, OEM, organoids expansion medium, Original Research, AFP, α-fetoprotein, Liver Neoplasms, Gastroenterology, ECM, extracellular matrix, Organoids, EpCAM, epithelial cell adhesion molecule, NSG, NOD scid γ mouse, FACS, fluorescence-activated cell sorter, 030211 gastroenterology & hepatology, Liver cancer, medicine.drug, Sorafenib, CCA, cholangiocarcinoma, Carcinoma, Hepatocellular, Stromal cell, Liver tumor, Primary Cell Culture, PBS, phosphate-buffered saline, Antineoplastic Agents, Biology, α-SMA, α-smooth muscle actin, Co-Culture, PDGFRA, platelet-derived growth factor receptor α, 03 medical and health sciences, Paracrine signalling, SDG 3 - Good Health and Well-being, 3D, 3-dimensional, Paracrine Communication, OBM, organoids basic medium, medicine, Animals, Humans, CAF, cancer-associated fibroblast, EGF, epidermal growth factor, Hepatology, Cancer, DEN, N-nitrosodiethylamine, medicine.disease, CSC, cancer stem cell, Xenograft Model Antitumor Assays, Coculture Techniques, FGF, fibroblast growth factor, IL, interleukin, 030104 developmental biology, Drug Resistance, Neoplasm, Culture Media, Conditioned, Cancer cell, Cancer research, TCGA, The Cancer Genome Atlas, DMEM, Dulbecco’s modified Eagle medium, 5-FU, 5-fluorouracil, HGF, hepatocyte growth factor, FCS, fetal calf serum, Stromal Cells, HCC, hepatocellular carcinoma

    وصف الملف: application/pdf

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    المصدر: Neoplasia (New York, N.Y.)
    Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 21-35 (2021)

    مصطلحات موضوعية: Proteomics, 0301 basic medicine, Cancer Research, Proteome, Colorectal cancer, Fluorescent Antibody Technique, TP53, tumor protein p53, Proto-Oncogene Mas, EREG, epiregulin, Metastasis, Mice, 0302 clinical medicine, BTC, betacellulin, Molecular Targeted Therapy, Epidermal growth factor receptor, Precision Medicine, biology, Cetuximab, GCN, gene copy number, TDT, tumor doubling time, APC, adenomatous polyposis coli, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, Primary tumor, Colorectal carcinoma, EpCAM, epithelial cell adhesion molecule, 030220 oncology & carcinogenesis, CRC, colorectal cancer, BRAF, proto-oncogene B-RAF, Heterografts, AKT, Serine threonine protein kinase AKT, Erlotinib, AREG, Amphiregulin, Technology Platforms, Colorectal Neoplasms, TNM, tumor nodule metastasis classification, medicine.drug, Original article, endocrine system, DNA Copy Number Variations, TGFα, transforming growth factor alfa, In vivo drug testing, Antineoplastic Agents, KRAS, Kirsten rat sarcoma virus oncogene homolog, mTOR, mammalian target of rapamycin, PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinaseM catalytic subunit alfa, lcsh:RC254-282, Genomic Instability, NSG mice, NOD scid gamma mice, 03 medical and health sciences, PDX, patient derived xenograft, Biomarkers, Tumor, medicine, Animals, Humans, IHC, imunno histochemistry, neoplasms, FFPE, formalin fixed paraffin embedded, EGF, epidermal growth factor, Betacellulin, Oncogene, business.industry, Gene Expression Profiling, medicine.disease, Xenograft Model Antitumor Assays, Personalized medicine, c-MET, tyrosine protein kinase MET, digestive system diseases, EGFR, epidermal growth factor receptor, 030104 developmental biology, Drug Resistance, Neoplasm, Patient-derived xenograft models, T/C, treated to control value, Mutation, Cancer research, biology.protein, 5-FU, 5-fluorouracil, HER2,3,4, human epidermal growth factor receptor 2,3,4, business, MAPK, mitogen activated protein kinase

    وصف الملف: application/pdf; application/msword

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    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1239-1250 (2021)
    Cellular and Molecular Gastroenterology and Hepatology

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    المصدر: Regenerative Therapy
    Regenerative Therapy, Vol 15, Iss, Pp 236-242 (2020)

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    المصدر: Acta Pharmaceutica Sinica. B
    Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)

    مصطلحات موضوعية: PEI, polyethylenimine, medicine.medical_treatment, MPO, myeloperoxidase, Review, ICAM, intercellular adhesion molecule, Inflammatory bowel disease, PSGL-1, P-selectin glycoprotein ligand-1, Targeted therapy, 0302 clinical medicine, Cell adhesion molecule, AIE, aggregation-induced emission, General Pharmacology, Toxicology and Pharmaceutics, CAM, cell adhesion molecule, HA, hyaluronic acid, ACQ, aggregation-caused quenching, media_common, FNII, fibronectin type II domain, 0303 health sciences, Crohn's disease, MGL, macrophage galactose lectin, IBD, inflammatory bowel disease, Ulcerative colitis, CT, computed tomography, 030220 oncology & carcinogenesis, Drug delivery, LPS, lipopolysaccharide, DCs, dendritic cells, Active target, CTLD, c-type lectin-like domain, MAP4K4, mitogen-activated protein kinase kinase kinase kinase 4, Drug, media_common.quotation_subject, RM1-950, TfR, transferrin receptor, FRET, fluorescence resonance energy transfer, ADR, adverse drug reaction, CS, chondroitin sulfate, 03 medical and health sciences, medicine, HUVEC, human umbilical vein endothelial cells, EPR, enhanced permeability and retention, CRD, cysteine-rich domain, 030304 developmental biology, MPS, mononuclear phagocyte system, EGF, epidermal growth factor, PAMAM, poly(amidoamine), business.industry, PepT1, peptide transporter 1, GIT, gastrointestinal tract, QDs, quantum dots, FR, folate receptor, Receptor-mediated target, medicine.disease, MR, mannose receptor, UC, ulcerative colitis, Targeted drug delivery, Cancer research, BSA, bovine serum albumin, CD, Crohn's disease, Therapeutics. Pharmacology, business, LMWC, low molecular weight chitosan, MRI, magnetic resonance imaging, RES, reticuloendothelial system, DSS, dextran sulfate sodium salt, VCAM, vascular cell adhesion molecule

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    المصدر: 'Journal of Molecular Biology ', vol: 432, pages: 5736-5751 (2020)
    Journal of Molecular Biology

    وصف الملف: application/pdf