المؤلفون: Ming-Hong Hao, E. Michael August, Danielle M. Fowler, Jin Mi Kim, Neil A. Farrow, Stéphane De Lombaert, Peter Allen Nemoto, Hidenori Takahashi, Leslie Martin, Daniel R. Albaugh, Steven S. Pullen, Kevin Chungeng Qian, Ho Yin Lo, Melissa Hill-Drzewi, Richard D. Schneiderman

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:4533-4539

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Chymases, Drug Discovery, Side chain, Humans, Moiety, Protease Inhibitors, Molecular Biology, Indole test, Binding Sites, Organic Chemistry, Chymase, Benzothiophene, Glutathione, Protein Structure, Tertiary, chemistry, Molecular Medicine, Benzimidazoles, Hydrophobic and Hydrophilic Interactions, Oxidation-Reduction, Lead compound, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df6a496eb118478cab46c6fde2569f9
https://doi.org/10.1016/j.bmcl.2011.05.126

المؤلفون: E. Michael August, Lana Louise Smith Keenan, Jun Li, S. Mariana Margarit, Alexander Heim-Riether, Hans-Dieter Junker, Kathleen Haverty, Neil A. Farrow, Brandon Collins, Bennett T. Farmer, Thomas Neumann, Shuang Liang, John R. Proudfoot, Renate Sekul, Qiang Zhang, Donghong Amy Gao, Steven John Taylor, Zhaoming Xiong, Neil Moss, Melissa Hill-Drzewi

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:5321-5324

مصطلحات موضوعية: Models, Molecular, Matrix metalloproteinase inhibitor, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Matrix Metalloproteinase Inhibitors, Biochemistry, Structure-Activity Relationship, Catalytic Domain, Matrix Metalloproteinase 13, Drug Discovery, medicine, Potency, Structure–activity relationship, Protease Inhibitors, Molecular Biology, Chelating Agents, chemistry.chemical_classification, biology, Organic Chemistry, Active site, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91cc7f3c887b95e837900c788a1ecfd
https://doi.org/10.1016/j.bmcl.2009.07.151

المؤلفون: Jerry L. Hopkins, Alisa K. Kabcenell, Anthony Shrutkowski, Daniel Rajotte, Elda Gautschi, Martha Priscilla Brown, Joey Studts, Lori Patnaude, E. Michael August, Anthony Kronkaitis

المصدر: SLAS Discovery. 11:816-821

مصطلحات موضوعية: Time Factors, medicine.medical_treatment, Histamine Antagonists, Fluorescence Polarization, Histidine Decarboxylase, Biochemistry, Analytical Chemistry, Inhibitory Concentration 50, chemistry.chemical_compound, medicine, Humans, Histidine, Enzyme Inhibitors, Receptor, chemistry.chemical_classification, biology, Molecular biology, Histidine decarboxylase, Enzyme, chemistry, biology.protein, Molecular Medicine, Histidine decarboxylase activity, Antihistamine, Antibody, Fluorescein-5-isothiocyanate, Histamine, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adadfe6ef29ff0778cf19382c31ce29
https://doi.org/10.1177/1087057106290803

المؤلفون: Victor E. Marquez, Daniel W. Zaharevitz, Richard L. Cysyk, Nancy Malinowski, E. Michael August, James D. Moyer

المصدر: Biochemical Pharmacology. 49:203-207

مصطلحات موضوعية: Pyrimidine, Uracil Nucleotides, Pharmacology, Biochemistry, Uridine kinase, Mice, chemistry.chemical_compound, In vivo, medicine, Animals, Leukemia L1210, Uracil, Uridine, Mice, Inbred BALB C, biology, chemistry, Mechanism of action, Mice, Inbred DBA, Enzyme inhibitor, Toxicity, biology.protein, Pyrimidine Nucleotides, Uridine Kinase, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f9c1ddfc51332d5487cc71d39176bb
https://doi.org/10.1016/0006-2952(94)00470-6

المؤلفون: Xiang Zhu, Anthony Kronkaitis, Melissa Hill-Drzewi, Gregory W. Peet, Teresa Roma, Daniela Cazacu, Irina Rybina, Leslie Martin, Alycia Shoultz, Louise K. Modis, Alistair Baptiste, Susan Lukas, Brian Christopher Raudenbush, E. Michael August

المصدر: Journal of biomolecular screening. 16(9)

مصطلحات موضوعية: Amine oxidase, AOC3, Monoamine oxidase, CHO Cells, Biochemistry, Analytical Chemistry, Inhibitory Concentration 50, Mice, In vivo, Cricetinae, medicine, Animals, Humans, Enzyme Inhibitors, Cell Line, Transformed, chemistry.chemical_classification, Chemistry, SIGLEC, Oxidative deamination, High-Throughput Screening Assays, Rats, Enzyme Activation, Enzyme, HEK293 Cells, Mechanism of action, Luminescent Measurements, Molecular Medicine, Amine Oxidase (Copper-Containing), medicine.symptom, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5f795bb37a1e0f24b86c487b06316f
https://pubmed.ncbi.nlm.nih.gov/21844327

المؤلفون: E. Michael August, William H. Prusoff, Lin Tai-Shun, Evelyn M. Birks, Qian He-Ying, Usha A. Thombre

المصدر: Biochemical Pharmacology. 45:223-230

مصطلحات موضوعية: DNA polymerase, Virus Replication, Antiviral Agents, Thymidine Kinase, Biochemistry, Thymidylate kinase, Cell Line, chemistry.chemical_compound, Deoxyadenosine, Idoxuridine, Humans, Phosphorylation, Pharmacology, biology, Uracil, DNA, DNA Polymerase II, Deoxyuridine, HIV Reverse Transcriptase, Reverse transcriptase, Uridine, Kinetics, chemistry, Thymidine kinase, Protein Biosynthesis, HIV-1, biology.protein, RNA, Reverse Transcriptase Inhibitors, Nucleoside-Phosphate Kinase, Thymidine, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e90a9c25e1540dfed9b6326e85e2b30
https://doi.org/10.1016/0006-2952(93)90396-e

المؤلفون: Shuang Liang, Kathleen Haverty, Donghong Amy Gao, Jun Li, Xiang Li, Sabine Schlyer, Alexander Heim-Riether, Melissa Hill-Drzewi, Steven John Taylor, Steluta Mariana Margarit, Lana Louise Smith Keenan, Neil Moss, Nelamangala V. Nagaraja, Xianhua Cao, Dieter Wiedenmayer, Neil A. Farrow, Kyle E. Harrington, Brandon Collins, E. Michael August, Leonard Ciccarelli, Rene Roman, Bernd Wellenzohn, Zhaoming Xiong, Laura Amodeo, John R. Proudfoot

المصدر: Bioorganicmedicinal chemistry letters. 20(17)

مصطلحات موضوعية: medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Matrix Metalloproteinase Inhibitors, Biochemistry, Chemical synthesis, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Chelation, Protease Inhibitors, Molecular Biology, Chelating Agents, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, Zinc, Enzyme, Enzyme inhibitor, Lipophilicity, biology.protein, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5361dabb2993b47e9d3285e7d2bb2c7
https://pubmed.ncbi.nlm.nih.gov/20675133

المؤلفون: E. Michael August, William H. Prusoff, Tai-Shun Lin, Mao‐Chin Liu, Evelyn M. Birks

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 29:1315-1321

مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Drug Discovery, Human immunodeficiency virus (HIV), medicine, Radiology, Nuclear Medicine and imaging, 3 azido 3 deoxythymidine, medicine.disease_cause, Biochemistry, Spectroscopy, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6cec6cd01f9ffd70653f3b9e8e659ad9
https://doi.org/10.1002/jlcr.2580291208

المؤلفون: William H. Prusoff, Ph. D, A Tai-shun Lin, E. Michael August, A Thomas G. Wood, Maria, Elena Marongiu, Ph. D. B

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/f2/49/Yale_J_Biol_Med_1989_Mar-Apr_62(2)_215-225.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.278.3317

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.278.3317

المؤلفون: Anne Monks, Kazimierz O. Wrzeszczynski, E. Michael August, Beverley A. Teicher, Annamaria Rapisarda, Dianne L. Newton, Eric C. Polley, Gurmeet Kaur, Sudhir Kondapaka

المصدر: Cancer Research. 73:4361-4361

مصطلحات موضوعية: Cancer Research, Drug discovery, Cancer, Bone Sarcoma, Pharmacology, Biology, medicine.disease, Fusion gene, Oncology, microRNA, Cancer research, medicine, Sarcoma, Rhabdomyosarcoma, Exome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e682030ea519eef74d9f0214d4fad141
https://doi.org/10.1158/1538-7445.am2013-4361

المؤلفون: Beverly A. Teicher, Thomas Silvers, Michael Selby, Rene Delosh, Julie Laudeman, Joel Morris, Russell Reinhart, E. Michael August, Chad Ogle

المصدر: Cancer Research. 73:5590-5590

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Pathology, business.industry, Cancer, medicine.disease, Vinorelbine, Synovial sarcoma, Gemcitabine, Pemetrexed, Floxuridine, Cabazitaxel, Internal medicine, medicine, Sarcoma, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c6480f91d6c7fbd2c9a30469e3bd4fb3
https://doi.org/10.1158/1538-7445.am2013-5590

المؤلفون: William H. Prusoff, E. Michael August

المصدر: Annals of the New York Academy of Sciences. 616:475-476

مصطلحات موضوعية: Human lymphocyte, History and Philosophy of Science, Mechanism (biology), Chemistry, Stereochemistry, General Neuroscience, General Biochemistry, Genetics and Molecular Biology, Ene reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ba91744a331a205ed61ee06b31f09d77
https://doi.org/10.1111/j.1749-6632.1990.tb17868.x

المؤلفون: E. Michael August

المصدر: Journal of Biomolecular Screening; Oct2006, Vol. 11 Issue 7, p816-821, 6p

المؤلفون: E. Michael August, Tai-Shun Lin, You-Song Gao, William H. Prusoff, He‐Ying Qian

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 27:669-674

مصطلحات موضوعية: Stereochemistry, Chemistry, Organic Chemistry, Drug Discovery, Human immunodeficiency virus (HIV), medicine, Radiology, Nuclear Medicine and imaging, medicine.disease_cause, Biochemistry, Spectroscopy, Ene reaction, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ca94affd05f2a4c2a2d192b36fc16f05
https://doi.org/10.1002/jlcr.2580270609