المؤلفون: Dustin T. King, Jesús E. Serrano-Negrón, Yanping Zhu, Christopher L. Moore, Matthew D. Shoulders, Leonard J. Foster, David J. Vocadlo

المصدر: J Am Chem Soc

مصطلحات موضوعية: Mammals, Proteomics, Colloid and Surface Chemistry, Proteome, Animals, General Chemistry, Protein Processing, Post-Translational, Biochemistry, Article, Catalysis, Acetylglucosamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9fb7539735bb76df15f45d676af59e
https://doi.org/10.1021/jacs.1c10621

المؤلفون: Roger A. Ashmus, Yang Wang, Manuel González-Cuesta, Dustin T. King, Ben Tiet, Xi Chen, Yanping Zhu, Bryce Kirk, Jos é M. García Fernandez, Carmen Ortiz Mellet, Robert Britton, David J Vocadlo

المصدر: Chemistry – A European Journal.

مصطلحات موضوعية: Organic Chemistry, General Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8ceaca1b6ef7c432eb2461ae7226b3e8
https://doi.org/10.1002/chem.202300982

المؤلفون: Dustin T. King, Bailey E. McGuire, Alisdair B. Boraston, David J. Vocadlo, Chelsea Vickers, Andrew G. Hettle

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Glycoside Hydrolases, Protein Conformation, galactose, Glycobiology and Extracellular Matrices, Carrageenan, Crystallography, X-Ray, Biochemistry, Fucose, glycoside-hydrolase, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Pseudoalteromonas, Catalytic Domain, structural biology, Glycoside hydrolase, glycoside hydrolase, blood group antigen, Molecular Biology, Phylogeny, X-ray crystallography, chemistry.chemical_classification, 030102 biochemistry & molecular biology, biology, Hydrolysis, Active site, Galactosides, Cell Biology, Galactan, biology.organism_classification, X-ray crystal structure, Enzyme structure, enzyme structure, galactosidase, 030104 developmental biology, Enzyme, chemistry, Galactose, biology.protein, Blood Group Antigens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5991482aa1eedc156f2f077e540c09a4
http://europepmc.org/articles/PMC7939477

المؤلفون: Solmaz Sobhanifar, Liam J Worrall, Dustin T King, Gregory A Wasney, Lars Baumann, Robert T Gale, Michael Nosella, Eric D Brown, Stephen G Withers, Natalie C J Strynadka

المصدر: PLoS Pathogens, Vol 12, Iss 12, p e1006067 (2016)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/5145b8a01c064e478e04e7f807981379

المؤلفون: Artem Cherkasov, Dustin T. King, Natalie C. J. Strynadka, Som S. Chatterjee, J. Andrew N. Alexander, Mariia Radaeva, Henry F. Chambers

المصدر: Journal of Biological Chemistry. 295:10870-10884

مصطلحات موضوعية: 0301 basic medicine, 030102 biochemistry & molecular biology, medicine.drug_class, Avibactam, Antibiotics, Cell Biology, Biology, medicine.disease_cause, Biochemistry, Methicillin-resistant Staphylococcus aureus, 3. Good health, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Antibiotic resistance, chemistry, Staphylococcus aureus, Gene expression, medicine, Molecular Biology, Gene, Integral membrane protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e4810b357e0162a1169d4102bc1b5be8
https://doi.org/10.1074/jbc.ra120.013029

المؤلفون: Carmen Ortiz Mellet, Manuel González-Cuesta, José M. García Fernández, Ben Tiet, David J. Vocadlo, Yang Wang, Dustin T. King, Pierre-André Gilormini, Robert Britton, Roger A. Ashmus

المصدر: Organicbiomolecular chemistry. 19(37)

مصطلحات موضوعية: 0303 health sciences, 010405 organic chemistry, Chemistry, Organic Chemistry, Cell, Rational design, Selective inhibition, 01 natural sciences, Biochemistry, Fabry patient, 0104 chemical sciences, 3. Good health, 03 medical and health sciences, Glycolipid, α galactosidase a, medicine.anatomical_structure, alpha-Galactosidase, medicine, Physical and Theoretical Chemistry, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9f2bf1985dfe3b83c1e20851cfb9c4
https://pubmed.ncbi.nlm.nih.gov/34494637

المؤلفون: Gideon J. Davies, David J. Vocadlo, Dustin T. King, Alexandra Males

المصدر: Current Opinion in Chemical Biology. 53:131-144

مصطلحات موضوعية: Transcriptional Activation, 0301 basic medicine, Cell physiology, Glycosylation, Hydrolases, N-Acetylglucosaminyltransferases, 010402 general chemistry, 01 natural sciences, Biochemistry, Acetylglucosamine, Substrate Specificity, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Glycosyltransferase, Humans, Transferase, Glycoside hydrolase, chemistry.chemical_classification, biology, Chemistry, 0104 chemical sciences, Cell biology, carbohydrates (lipids), Metabolic pathway, 030104 developmental biology, Enzyme, biology.protein, Glycoprotein, Protein Processing, Post-Translational

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ce24e3fc8d052a38b87ce6b4d6c4fd
https://doi.org/10.1016/j.cbpa.2019.09.001

المؤلفون: Dustin T King, Mark Barnes, Dana Thomsen, Chow H Lee

المصدر: PLoS ONE, Vol 9, Iss 3, p e91585 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3951440?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/77535403bb1a41d9b0fc94dabef35743

المؤلفون: Dustin T. King, Matthew G. Alteen, Edwin E. Escobar, Jennifer S. Brodbelt, Jesús E. Serrano-Negrón, David J. Vocadlo

المصدر: J Am Chem Soc

مصطلحات موضوعية: Stereochemistry, Ultraviolet Rays, Polyhomeotic, Oxocarbenium, Peptide, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Biochemistry, Catalysis, Article, Mass Spectrometry, Acetylglucosamine, Colloid and Surface Chemistry, Dogs, Fragmentation (mass spectrometry), Animals, chemistry.chemical_classification, Chemistry, Photodissociation, Proteins, Glycosidic bond, General Chemistry, Photochemical Processes, 0104 chemical sciences, Proteome, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5dbe6f17f00c484e94df186061c07a
http://summit.sfu.ca/item/20486

المؤلفون: Fahimeh S. Shidmoossavee, Saeideh Shamsi Kazem Abadi, Chloe A. N. Gerak, Natalia Sannikova, Andrew J. Bennet, Dustin T. King, Andrew R. Lewis

المصدر: Biochemistry. 57:3378-3386

مصطلحات موضوعية: 0301 basic medicine, Glycoside Hydrolases, Stereochemistry, Molecular Conformation, Biochemistry, Cofactor, 03 medical and health sciences, Hydrolysis, Kinetic isotope effect, Glycoside hydrolase, biology, Chemistry, Leaving group, Galactose, NAD, biology.organism_classification, Citrobacter freundii, Kinetics, 030104 developmental biology, Deuterium, 13. Climate action, Biocatalysis, biology.protein, NAD+ kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5cc0b371c3bfccc5851ee6ab8d4997
https://doi.org/10.1021/acs.biochem.8b00117

المؤلفون: J Andrew N, Alexander, Mariia, Radaeva, Dustin T, King, Henry F, Chambers, Artem, Cherkasov, Som S, Chatterjee, Natalie C J, Strynadka

المصدر: J Biol Chem

مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, Molecular Docking Simulation, Bacterial Proteins, Genes, Bacterial, Protein Conformation, Protein Stability, Drug Resistance, Microbial, Editors' Picks, Gene Expression Regulation, Bacterial, Crystallography, X-Ray, beta-Lactamase Inhibitors, Azabicyclo Compounds

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::706f3daf9d331490a9a0b5a4642d7bec
https://pubmed.ncbi.nlm.nih.gov/32518158

المؤلفون: Natalie C. J. Strynadka, Dustin T. King, Anita Fong, Michael Nosella, Gregory A. Wasney

المصدر: Journal of Biological Chemistry. 292:979-993

مصطلحات موضوعية: 0301 basic medicine, Penicillin binding proteins, Protein domain, Crystallography, X-Ray, beta-Lactams, 010402 general chemistry, medicine.disease_cause, Microbiology, 01 natural sciences, Biochemistry, Cell wall, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Glycosyltransferase, medicine, Penicillin-Binding Proteins, Molecular Biology, Escherichia coli, Peptidoglycan glycosyltransferase, Escherichia coli K12, biology, Escherichia coli Proteins, Active site, Cell Biology, Serine-Type D-Ala-D-Ala Carboxypeptidase, 0104 chemical sciences, 3. Good health, 030104 developmental biology, chemistry, biology.protein, Peptidoglycan Glycosyltransferase, Peptidoglycan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b576cac9d9984138b9b9c8bb7579bf
https://doi.org/10.1074/jbc.m116.718403

المؤلفون: Natalie C. J. Strynadka, Solmaz Sobhanifar, Dustin T. King

المصدر: Protein Science. 25:787-803

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, 030106 microbiology, Arms race, Antibiotics, Biology, Biochemistry, Microbiology, 03 medical and health sciences, 030104 developmental biology, Multidrug resistant bacteria, Antibiotic resistance, Political economy, β lactams, medicine, Molecular Biology, Beta-Lactamase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f2de5f7624b3f2cb1d23acdb9710da6d
https://doi.org/10.1002/pro.2889

المؤلفون: Gerard D. Wright, Eric Brouillette, J. Andrew N. Alexander, Marija Vuckovic, Eric D. Brown, Samarendra N. Maiti, Dustin T. King, Andrew M. King, Natalie C. J. Strynadka, Abdelhamid Asli, Shawn French, François Malouin, Thomas R. Parr

المصدر: ACS Chemical Biology. 11:864-868

مصطلحات موضوعية: 0301 basic medicine, Penicillin binding proteins, Protein Conformation, medicine.drug_class, Avibactam, 030106 microbiology, Antibiotics, Microbial Sensitivity Tests, Biology, medicine.disease_cause, Biochemistry, Microbiology, 03 medical and health sciences, chemistry.chemical_compound, medicine, Penicillin-Binding Proteins, Escherichia coli, Beta-Lactamase Inhibitors, Drug discovery, General Medicine, Enterobacter, biology.organism_classification, Antimicrobial, 3. Good health, Kinetics, 030104 developmental biology, chemistry, Molecular Medicine, beta-Lactamase Inhibitors, Azabicyclo Compounds

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6035bcd8a4a45a55aa9d8b304da1445
https://doi.org/10.1021/acschembio.5b00944

المؤلفون: Dustin T. King, Isao Adachi, David J. Vocadlo, Atsushi Kato, David Deniaud, Jérôme Désiré, Yves Blériot, Sébastien G. Gouin, Thibaut Legigan, Dimitri Alvarez-Dorta, Daisuke Ide

المساهمون: Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Hospital Pharmacy [Toyama], University of Toyama, Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Département de pharmacochimie moléculaire (DPM ), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers-Institut de Chimie du CNRS (INC)

المصدر: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, 23 (38), pp.9022-9025. ⟨10.1002/chem.201701756⟩

مصطلحات موضوعية: Ethylene Glycol, Stereochemistry, Iminosugar, 010402 general chemistry, 01 natural sciences, Catalysis, chemistry.chemical_compound, Glucoside, Glucosides, [CHIM]Chemical Sciences, Animals, Glycoside hydrolase, Enzyme Inhibitors, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Cyclodextrins, Cyclodextrin, 010405 organic chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Organic Chemistry, General Chemistry, Azepines, Plants, 0104 chemical sciences, Hexosaminidases, Anti-Bacterial Agents, Imino Sugars, Inhibitory potency, chemistry, Selectivity, Ethylene glycol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd73e11ec696e53145a21636793ce4de
http://summit.sfu.ca/item/20512

المؤلفون: Dustin T. King, Emilie Lameignere, Natalie C. J. Strynadka

المصدر: Journal of Biological Chemistry. 289:19245-19253

مصطلحات موضوعية: Models, Molecular, Penicillin binding proteins, Lipoproteins, Molecular Sequence Data, Plasma protein binding, Braun's lipoprotein, Biology, Crystallography, X-Ray, Biochemistry, Protein Structure, Secondary, Cell wall, chemistry.chemical_compound, Escherichia coli, Penicillin-Binding Proteins, Amino Acid Sequence, Protein Structure, Quaternary, Molecular Biology, Peptidoglycan glycosyltransferase, Escherichia coli Proteins, Cell Membrane, Salmonella enterica, Cell Biology, biology.organism_classification, Serine-Type D-Ala-D-Ala Carboxypeptidase, Enterobacteriaceae, Cell biology, chemistry, Peptidoglycan Glycosyltransferase, Peptidoglycan, Protein Multimerization, Bacterial outer membrane, Molecular Biophysics, Bacterial Outer Membrane Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde15120d6c7e9bfe66189cc6572fd12
https://doi.org/10.1074/jbc.m114.565879

المؤلفون: Laura Marrone, Dylan R. Pillai, Jürgen Brem, Carol A. Tanner, Valerie J. Goodfellow, Stefan Siemann, Ahmad Ghavami, James Spencer, Natalie C. J. Strynadka, Dustin T. King, Geneviève Labbé, Christopher J. Schofield, Melinda Lam, Gary I. Dmitrienko

المصدر: Analytical Biochemistry. 486:75-77

مصطلحات موضوعية: medicine.drug_class, Cephalosporin, Drug Evaluation, Preclinical, Biophysics, Chemistry Techniques, Synthetic, Biochemistry, beta-Lactamases, Hydrolysis, medicine, Nitrocefin, Organic chemistry, Molecular Biology, biology, Drug discovery, Chemistry, Cell Biology, biology.organism_classification, Chromogenic Compounds, Combinatorial chemistry, In vitro, Cephalosporins, Kinetics, Biocatalysis, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a90dfba1097be24f26ad08d8f7fb729
https://doi.org/10.1016/j.ab.2015.06.032

المؤلفون: Dustin T. King, Natalie C. J. Strynadka, Solmaz Sobhanifar

المصدر: Current Opinion in Structural Biology. 23:695-703

مصطلحات موضوعية: Glycosylation, Bacteria, Microbial metabolism, Morphogenesis, Peptidoglycan, Biology, Bacterial growth, Bacterial cell structure, Cell biology, Cell wall, chemistry.chemical_compound, Metabolic balance, chemistry, Biochemistry, Cell Wall, Structural Biology, Degradation (geology), Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4887f8a950316bd2c313d2bbc98b5449
https://doi.org/10.1016/j.sbi.2013.07.008

المؤلفون: Dustin T. King, Natalie C. J. Strynadka

المصدر: Future Medicinal Chemistry. 5:1243-1263

مصطلحات موضوعية: medicine.drug_class, Cephalosporin, Antibiotics, Penicillins, Biology, beta-Lactam Resistance, beta-Lactamases, Metallo β lactamase, Microbiology, Human health, Antibiotic resistance, Catalytic Domain, Drug Discovery, medicine, Humans, Sulfhydryl Compounds, Enzyme Inhibitors, Structural approach, Pharmacology, chemistry.chemical_classification, Bacteria, Aptamers, Nucleotide, bacterial infections and mycoses, biology.organism_classification, Cephalosporins, Enzyme, Carbapenems, chemistry, Molecular Medicine, beta-Lactamase Inhibitors, Cyclobutanes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce5f32c068c6ac0b205ef7cb70afb31
https://doi.org/10.4155/fmc.13.55

المؤلفون: G. R. Benzie, Jérôme Désiré, Yves Blériot, B. Iorga, Brian L. Mark, David J. Vocadlo, Jaufret Bouquet, Atsushi Kato, Dustin T. King, Grishma Vadlamani, Isao Adachi, Daisuke Ide

المساهمون: Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP), Université de Poitiers-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Simon Fraser University (SFU.ca), Department of Medical Microbiology, Community Health Sciences and Medicine, University of Manitoba, Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Department of Hospital Pharmacy [Toyama], University of Toyama, JB thanks 'Vaincre la Mucoviscidose' for a PhD fellowship and financial support. DJV is supported as a Tier I Canada Research Chair in Chemical Glycobiology. BLM and DJV thanks Cystic Fibrosis Canada and the Canadian Institutes of Health Research for financial support (PJT-148496). This work was supported in part by a Grant-in-Aid for Scientific Research (C) (JP26460143) (AK) from the Japanese Society for the Promotion of Science (JSPS)., Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers-Institut de Chimie du CNRS (INC)

المصدر: Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2017, 15 (21), pp.4609-4619. ⟨10.1039/C7OB00838D⟩

مصطلحات موضوعية: Glycoside Hydrolases, Stereochemistry, Protein Conformation, Triazole, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, 010402 general chemistry, medicine.disease_cause, Hydroxylation, beta-Lactams, 01 natural sciences, Biochemistry, Ceftazidime, chemistry.chemical_compound, Azepane, medicine, Physical and Theoretical Chemistry, Glucosaminidase, Sulfamide, 010405 organic chemistry, Pseudomonas aeruginosa, Organic Chemistry, Drug Synergism, Azepines, [CHIM.CATA]Chemical Sciences/Catalysis, HEXA, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, 0104 chemical sciences, 3. Good health, Hexosaminidases, Anti-Bacterial Agents, Molecular Docking Simulation, chemistry, Lactam

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356b524cd4fdb70eec3f84a3d42365e1
https://hal.archives-ouvertes.fr/hal-02176734