المؤلفون: Peter Verstraelen, Samuel Van Remoortel, Nouchin De Loose, Rosanne Verboven, Gerardo Garcia-Diaz Barriga, Anne Christmann, Manuela Gries, Shingo Bessho, Jing Li, Carmen Guerra, Çagla Tükel, Sales Ibiza Martinez, Karl-Herbert Schäfer, Jean-Pierre Timmermans, Winnok H. De Vos

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 89-104 (2024)

مصطلحات موضوعية: Microbiome–Gut–Brain Axis, Curli, Enteric Nervous System, Serum Amyloid A3, Dual Leucine Zipper Kinase, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X24000687; https://doaj.org/toc/2352-345X

URL الوصول: https://doaj.org/article/9e6f75de89f84982823a97136cab22fe

المؤلفون: Kyra-Alexandra Köster, Marten Dethlefs, Jorge Duque Escobar, Elke Oetjen

المصدر: Cells, Vol 13, Iss 4, p 333 (2024)

مصطلحات موضوعية: dual leucine zipper kinase, phosphorylation, protein–protein interaction, proteasomal degradation, palmitoylation, Cytology, QH573-671

Relation: https://www.mdpi.com/2073-4409/13/4/333; https://doaj.org/toc/2073-4409; https://doaj.org/article/e1ce1ad77a894886b5f20b2834e04279

الاتاحة: https://doi.org/10.3390/cells13040333
https://doaj.org/article/e1ce1ad77a894886b5f20b2834e04279

المؤلفون: Welsbie, Derek S, Ziogas, Nikolaos K, Xu, Leyan, Kim, Byung-Jin, Ge, Yusong, Patel, Amit K, Ryu, Jiwon, Lehar, Mohamed, Alexandris, Athanasios S, Stewart, Nicholas, Zack, Donald J, Koliatsos, Vassilis E

المصدر: Molecular Neurodegeneration. 14(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Brain Disorders, Neurosciences, Physical Injury - Accidents and Adverse Effects, Traumatic Head and Spine Injury, Traumatic Brain Injury (TBI), Aetiology, 2.1 Biological and endogenous factors, Neurological, Animals, Brain Injuries, Traumatic, Cell Survival, Disease Models, Animal, Leucine Zippers, MAP Kinase Kinase Kinases, MAP Kinase Signaling System, Male, Mice, Inbred C57BL, Neurons, Protein Kinase Inhibitors, Retinal Ganglion Cells, Traumatic axonal injury, Concussion, Cell death, Traumatic brain injury, Optic neuropathy, Dual leucine zipper kinase, DLK, LZK, Retinal ganglion cell, Genetics, Clinical Sciences, Neurology & Neurosurgery, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8fn1s6m1
https://escholarship.org/content/qt8fn1s6m1/qt8fn1s6m1.pdf

المؤلفون: Fernandes, Kimberly A, Mitchell, Katherine L, Patel, Amit, Marola, Olivia J, Shrager, Peter, Zack, Donald J, Libby, Richard T, Welsbie, Derek S

مصطلحات موضوعية: Physical Injury - Accidents and Adverse Effects, Traumatic Head and Spine Injury, Eye Disease and Disorders of Vision, Neurosciences, Neurodegenerative, Aetiology, 2.1 Biological and endogenous factors, Eye, Neurological, Animals, Apoptosis, Armadillo Domain Proteins, Axons, Cell Count, Cell Survival, Cytoskeletal Proteins, Disease Models, Animal, Electrophysiology, Immunohistochemistry, Mice, Mice, Inbred C57BL, Mice, Knockout, Nerve Crush, Optic Nerve Injuries, Receptors, Tumor Necrosis Factor, Retinal Degeneration, Retinal Ganglion Cells, Sterile alpha and TIR motif containing 1, Dual leucine zipper kinase, Axon degeneration, Retinal ganglion cell, Neurodegenerative disease, Medical Biochemistry and Metabolomics, Opthalmology and Optometry, Ophthalmology & Optometry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1054d8tr

المؤلفون: Chen Jiang, Weilin Fang, Tingting Lv, Yinjun Gu, Jianwei Lv

المصدر: Journal of Innate Immunity, Pp 1-10 (2021)

مصطلحات موضوعية: dual leucine zipper kinase, cystitis, bladder pain, inflammation, sensory neuron, Medicine, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: https://www.karger.com/Article/FullText/514545; https://doaj.org/toc/1662-811X; https://doaj.org/toc/1662-8128

URL الوصول: https://doaj.org/article/247658e58eaf4ffaa373ba25f343206e

المؤلفون: Derek S. Welsbie, Nikolaos K. Ziogas, Leyan Xu, Byung-Jin Kim, Yusong Ge, Amit K. Patel, Jiwon Ryu, Mohamed Lehar, Athanasios S. Alexandris, Nicholas Stewart, Donald J. Zack, Vassilis E. Koliatsos

المصدر: Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-18 (2019)

مصطلحات موضوعية: Traumatic axonal injury, Concussion, Cell death, Traumatic brain injury, Optic neuropathy, Dual leucine zipper kinase, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13024-019-0345-1; https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/514b71f5220a494fa1e744e64eb61a2e

المؤلفون: Jung Eun Shin, Hongseok Ha, Yoon Ki Kim, Yongcheol Cho, Aaron DiAntonio

المصدر: Neurobiology of Disease, Vol 127, Iss , Pp 178-192 (2019)

مصطلحات موضوعية: Dual leucine zipper kinase, Conditioning injury, Axon regeneration, Neuroinflammation, Neurodegeneration, Pain, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996118305370; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/61b1dcf5f9fd4b019c439db7fb381a9e

المؤلفون: Sean R Cuddy, Austin R Schinlever, Sara Dochnal, Philip V Seegren, Jon Suzich, Parijat Kundu, Taylor K Downs, Mina Farah, Bimal N Desai, Chris Boutell, Anna R Cliffe

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: herpes simplex virus, IL-1, epigenetics, dual leucine zipper kinase, hyperexcitability, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/58037; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/0fb97c7a33404ae3886ae03f37e70bc9

المؤلفون: Duque Escobar, Jorge Enrique

مصطلحات موضوعية: Dual Leucine-Zipper Kinase, dual leucine zipper kinase, nuclear export signal, beta cell apoptosis, calcineurin, 610 Medizin, Gesundheit, 44.38 Pharmakologie, Calcineurin, Diabetes mellitus, Ciclosporin, Tacrolimus, CREB, B-Zelle, Apoptosis, Langerhans-Inseln, MAP-Kinase, Tumor-Nekrose-Faktor, ddc:610

URL الوصول: http://nbn-resolving.de/urn:nbn:de:gbv:18-86221
https://ediss.sub.uni-hamburg.de/handle/ediss/7280

المؤلفون: Dhurgadevi Kr, Jeyakanthan Jeyaraman, Biswas A, Langeswaran K, R Jb

المصدر: Journal of Receptors and Signal Transduction. 39:99-105

مصطلحات موضوعية: 0301 basic medicine, Dual leucine zipper kinase DLK, MAP Kinase Signaling System, Protein Conformation, Pyridines, Cell, Molecular Dynamics Simulation, Ligands, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Catalytic Domain, medicine, Humans, Enzyme Inhibitors, Protein Kinase Inhibitors, Molecular Biology, Cells, Cultured, Neurons, Chemistry, Kinase, Calcium-Binding Proteins, JNK Mitogen-Activated Protein Kinases, Membrane Proteins, Cell Biology, Cell biology, Structure and function, Molecular Docking Simulation, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, DUAL LEUCINE ZIPPER KINASE, Pyrazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2ce80870b6bb244c9015961ff55f06
https://doi.org/10.1080/10799893.2019.1620776

المؤلفون: Girouard, Marie-Pier, Bueno, Mardja, Julian, Victoria, Drake, Sienna, Byrne, Alexandra B., Fournier, Alyson E.

المساهمون: Graduate School of Biomedical Sciences, Neuroscience Program, Byrne Lab, Neurobiology, Victoria Julian Czech

المصدر: Developmental neurobiology

مصطلحات موضوعية: Stathmin (SCG10), Wallerian degeneration, axon regeneration, calpain, cytoskeleton, dual leucine zipper kinase, mitochondria, nicotinamide mononucleotide adenylyltransferase (NMNAT), Developmental Neuroscience, Molecular and Cellular Neuroscience

Relation: Link to Article in PubMed; https://doi.org/10.1002/dneu.22627; Dev Neurobiol. 2018 Jul 18. doi:10.1002/dneu.22627. Link to article on publisher's site; 1932-8451 (Linking); http://hdl.handle.net/20.500.14038/37960; https://escholarship.umassmed.edu/neurobiology_pp/233; neurobiology_pp/233

الاتاحة: https://doi.org/10.1002/dneu.22627
https://hdl.handle.net/20.500.14038/37960
https://escholarship.umassmed.edu/neurobiology_pp/233

المؤلفون: E Oetjen, K-A Köster

المصدر: Präzisionsmedizin – Eine Reise in die Zukunft der Diabetologie www.diabeteskongress.de.

مصطلحات موضوعية: Mutation, Dual leucine zipper kinase DLK, Chemistry, medicine, Hamster, CRISPR, Beta cell, medicine.disease_cause, Function (biology), Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9f16a513b4190800364ca378a3d0873c
https://doi.org/10.1055/s-0041-1727376

المؤلفون: Hanley, Nicole Marie

مصطلحات موضوعية: claudin-5, epilepsy, psychiatric disorders, Blood-brain barrier, therapy, dual leucine zipper kinase

Relation: Hanley, Nicole Marie, Identifying Blood-Brain Barrier Pathologies and Novel Therapeutic Targets in Epilepsy and Neuropsychiatric Disorders, Trinity College Dublin, School of Genetics & Microbiology, Genetics, 2022; Y; http://hdl.handle.net/2262/101559; https://tcdlocalportal.tcd.ie/pls/EnterApex/f?p=800:71:0::::P71_USERNAME:NIHANLEY; 247339

الاتاحة: http://hdl.handle.net/2262/101559
https://tcdlocalportal.tcd.ie/pls/EnterApex/f?p=800:71:0::::P71_USERNAME:NIHANLEY

المؤلفون: Taylor K Downs, Anna R. Cliffe, Sara Dochnal, Mina Farah, Chris Boutell, Jon B. Suzich, Austin R Schinlever, Parijat Kundu, Bimal N. Desai, Philip V. Seegren, Sean R Cuddy

المصدر: eLife
eLife, Vol 9 (2020)

مصطلحات موضوعية: Mouse, QH301-705.5, Science, viruses, dual leucine zipper kinase, Interleukin-1beta, Stimulation, Herpesvirus 1, Human, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Mice, medicine, Animals, Epigenetics, Biology (General), Histone demethylase activity, Neurons, Microbiology and Infectious Disease, Innate immune system, Forskolin, General Immunology and Microbiology, epigenetics, IL-1, General Neuroscience, hyperexcitability, Herpes Simplex, General Medicine, MAP Kinase Kinase Kinases, herpes simplex virus, Cell biology, Virus Latency, Herpes simplex virus, Histone phosphorylation, chemistry, Neuronal Hyperexcitability, Medicine, Virus Activation, Other, Research Article, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e854dd23ac87bd831ed06d5591025f4b
https://pubmed.ncbi.nlm.nih.gov/33350386

المؤلفون: Michael Siu, Arundhati Sengupta Ghosh, Joseph W. Lewcock

المصدر: Journal of Medicinal Chemistry. 61:8078-8087

مصطلحات موضوعية: 0301 basic medicine, Chemistry, Neurodegeneration, medicine.disease, Small molecule, Cell biology, 03 medical and health sciences, 030104 developmental biology, In vivo, Calcium-binding protein, Drug Discovery, DUAL LEUCINE ZIPPER KINASE, medicine, Molecular Medicine, Neuronal degeneration, Kinase activity, Therapeutic strategy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::09aa713754ee5e532b916801ac5ef2a7
https://doi.org/10.1021/acs.jmedchem.8b00370

المؤلفون: Amit K Patel, Donald J. Zack, Yusong Ge, Jiwon Ryu, Byung Jin Kim, Derek S. Welsbie, Vassilis E. Koliatsos, Leyan Xu, Mohamed Lehar, Nikolaos K. Ziogas, Nicholas Stewart, Athanasios S. Alexandris

المصدر: Molecular neurodegeneration, vol 14, iss 1
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-18 (2019)
Molecular Neurodegeneration

مصطلحات موضوعية: 0301 basic medicine, Retinal Ganglion Cells, Male, Traumatic, medicine.medical_treatment, Concussion, lcsh:Geriatrics, Optic neuropathy, Inbred C57BL, lcsh:RC346-429, Traumatic axonal injury, Mice, 0302 clinical medicine, Traumatic brain injury, Injury - Trauma - (Head and Spine), Brain Injuries, Traumatic, 2.1 Biological and endogenous factors, Retinal ganglion cell, Aetiology, Axon, Neurons, Kinase, Neurodegeneration, Protein kinase inhibitor, MAP Kinase Kinase Kinases, Cell biology, Dual leucine zipper kinase, medicine.anatomical_structure, Neurological, Axotomy, DLK, Research Article, Cell death, Leucine zipper, medicine.drug_class, Cell Survival, MAP Kinase Signaling System, Clinical Sciences, Biology, Retinal ganglion, Neuroprotection, 03 medical and health sciences, Cellular and Molecular Neuroscience, medicine, Genetics, Animals, Molecular Biology, Protein Kinase Inhibitors, lcsh:Neurology. Diseases of the nervous system, Leucine Zippers, Neurology & Neurosurgery, Animal, Neurosciences, medicine.disease, Brain Disorders, Mice, Inbred C57BL, LZK, Disease Models, Animal, lcsh:RC952-954.6, 030104 developmental biology, Brain Injuries, Disease Models, Injury (total) Accidents/Adverse Effects, Neurology (clinical), Injury - Traumatic brain injury, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131d4bd09d928f5dbb4f0685c1fe85da
https://escholarship.org/uc/item/8fn1s6m1

المؤلفون: Mieke Verslegers, Rony Nuydens, Peter Larsen, Emma Coninx, Ines Cilissen, Marlies Verschuuren, Gerardo García-Díaz Barriga, Peter Verstraelen, Winnok H. De Vos

المصدر: Acta neuropathologica communications
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)

مصطلحات موضوعية: 0301 basic medicine, Neuronal network, Calcium imaging, Neuronal connectivity, Neuroprotection, lcsh:RC346-429, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Microtubule, Microscopy, medicine, Biological neural network, Neurodegeneration, lcsh:Neurology. Diseases of the nervous system, Chemistry, Methodology Article, High-content screening, Antioxidant depletion, hTau.P301L, medicine.disease, Synapse, Cell biology, 030104 developmental biology, DUAL LEUCINE ZIPPER KINASE, Human medicine, Neurology (clinical), 030217 neurology & neurosurgery

وصف الملف: pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c762938db2362b8b67f1cd112ce745c1
https://doi.org/10.1186/s40478-019-0741-3

المؤلفون: Amy Gustafson, Michael Siu, Reina N. Fuji, Anthony A. Estrada, Jinhua Chen, Jianping Yin, Gauri Deshmukh, Yichin Liu, Seth F. Harris, Jose Imperio, Rebecca Erickson, William J. Meilandt, Changyou Ma, Snahel Patel, Joseph P. Lyssikatos, Paul Gibbons, Wendy Liu, Xingrong Liu, Joseph W. Lewcock

المصدر: Journal of medicinal chemistry. 60(19)

مصطلحات موضوعية: 0301 basic medicine, Drug, Models, Molecular, Multiple days, Dual leucine zipper kinase DLK, media_common.quotation_subject, Regulator, Disease, Rats, Sprague-Dawley, 03 medical and health sciences, Amyloid beta-Protein Precursor, Mice, Structure-Activity Relationship, 0302 clinical medicine, Alzheimer Disease, Drug Discovery, Animals, Humans, Neuronal degeneration, Enzyme Inhibitors, media_common, Chemistry, Kinase, Brain, MAP Kinase Kinase Kinases, Cell biology, Rats, Mice, Inbred C57BL, Macaca fascicularis, 030104 developmental biology, Biochemistry, Drug Design, DUAL LEUCINE ZIPPER KINASE, Molecular Medicine, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eef807727b6c9e2cd49383f0d8faf26
https://pubmed.ncbi.nlm.nih.gov/28929759

المؤلفون: Yichin Liu, Frederick Cohen, Bei Wang, Joseph W. Lewcock, Kimberly L. Stark, Brian Dean, Young G. Shin, Arundhati Sengupta Ghosh, Kelly De La Torre, Paul Gibbons, Joseph P. Lyssikatos, Claire E. Le Pichon, Wendy Liu, Jian Wang, Michael Siu, Xingrong Liu, Snahel Patel, Malcolm P. Huestis, Han Lin, Changyou Ma, Amy Gustafson, Anthony A. Estrada, Gauri Deshmukh, Xianrui Zhao, Kimberly Scearce-Levie, Cuong Ly, Hilda Solanoy

المصدر: Journal of Medicinal Chemistry. 58:401-418

مصطلحات موضوعية: Dual leucine zipper kinase DLK, Regulator, Madin Darby Canine Kidney Cells, Dogs, Drug Discovery, medicine, Animals, Humans, Neuronal degeneration, Protein Kinase Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, Drug discovery, Chemistry, HEK 293 cells, Neurodegeneration, Neurodegenerative Diseases, MAP Kinase Kinase Kinases, medicine.disease, In vitro, Rats, Cell biology, Mice, Inbred C57BL, Disease Models, Animal, HEK293 Cells, Models, Chemical, Biochemistry, Nerve Degeneration, DUAL LEUCINE ZIPPER KINASE, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79efe4ad303e722a20a7b244525eeda
https://doi.org/10.1021/jm5013984

المؤلفون: Thomas Lemcke, Elke Oetjen

المصدر: Expert Opinion on Therapeutic Patents. 26:607-616

مصطلحات موضوعية: 0301 basic medicine, Computational biology, Biology, Mixed Lineage Kinase, Patents as Topic, Mice, 03 medical and health sciences, Drug Discovery, medicine, Animals, Humans, In patient, Pharmacology, MAP kinase kinase kinase, Regeneration (biology), Neurodegeneration, Neurodegenerative Diseases, General Medicine, MAP Kinase Kinase Kinases, Highly selective, medicine.disease, Axons, Nerve Regeneration, Atp competitive, Disease Models, Animal, 030104 developmental biology, Biochemistry, Drug Design, DUAL LEUCINE ZIPPER KINASE

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c91cf4436f65c59aa2fc13bc9e548a
https://doi.org/10.1517/13543776.2016.1170810