المؤلفون: Sonowal, Himangshu, Rice, William, Bejar, Rafael, Byun, Joo-Yun, Jung, Seung, Sinha, Ranjeet, Howell, Stephen

المصدر: Cancer Research Communications. 5(1)

مصطلحات موضوعية: Leukemia, Myeloid, Acute, Humans, Protein Kinase Inhibitors, Animals, Pyrimidines, Mice, Drug Evaluation, Preclinical, Antineoplastic Agents, Cell Line, Tumor, Clinical Trials, Phase I as Topic

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3qr061j8
https://escholarship.org/content/qt3qr061j8/qt3qr061j8.pdf

المؤلفون: Sen, Chandani, Rickabaugh, Tammy M, Jeyachandran, Arjit Vijey, Yuen, Constance, Ghannam, Maisam, Durra, Abdo, Aziz, Adam, Castillo, Kristen, Garcia, Gustavo, Purkayastha, Arunima, Han, Brandon, Boulton, Felix W, Chekler, Eugene, Garces, Robert, Wolff, Karen C, Riva, Laura, Kirkpatrick, Melanie G, Gebara-Lamb, Amal, McNamara, Case W, Betz, Ulrich AK, Arumugaswami, Vaithilingaraja, Damoiseaux, Robert, Gomperts, Brigitte N

المصدر: Respiratory Research. 26(1)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Lung, Coronaviruses, Emerging Infectious Diseases, Infectious Diseases, Stem Cell Research, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Humans, SARS-CoV-2, Antiviral Agents, High-Throughput Screening Assays, Drug Evaluation, Preclinical, Respiratory Mucosa, COVID-19 Drug Treatment, COVID-19, Cells, Cultured, Human mucociliary epithelium, Respiratory viral infections, High throughput drug screening, Anti-viral screening, Small-molecules, Air-liquid-interface, Heterogeneity, Image quantification, RNA sequencing, Air–liquid-interface, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Respiratory System, Cardiovascular medicine and haematology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0q6105cw
https://escholarship.org/content/qt0q6105cw/qt0q6105cw.pdf

المؤلفون: Ramani, Anand, Pasquini, Giovanni, Gerkau, Niklas, Jadhav, Vaibhav, Vinchure, Omkar, Altinisik, Nazlican, Windoffer, Hannes, Muller, Sarah, Rothenaigner, Ina, Lin, Sean, Mariappan, Aruljothi, Rathinam, Dhanasekaran, Mirsaidi, Ali, Goureau, Olivier, Ricci-Vitiani, Lucia, DAlessandris, Quintino, Wollnik, Bernd, Muotri, Alysson, Freifeld, Limor, Jurisch-Yaksi, Nathalie, Pallini, Roberto, Rose, Christine, Busskamp, Volker, Gabriel, Elke, Hadian, Kamyar, Gopalakrishnan, Jay

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Organoids, Humans, Microcephaly, Glioma, Drug Evaluation, Preclinical, Brain, Brain Neoplasms, Animals, Reproducibility of Results, Benzimidazoles, Mice, Cell Line, Tumor, Neoplasm Invasiveness

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4nj7d7q1
https://escholarship.org/content/qt4nj7d7q1/qt4nj7d7q1.pdf

المؤلفون: Gendelev, Leo, Taylor, Jack, Myers-Turnbull, Douglas, Chen, Steven, McCarroll, Matthew, Arkin, Michelle, Kokel, David, Keiser, Michael

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Zebrafish, Animals, Larva, Phenotype, Drug Discovery, Behavior, Animal, High-Throughput Screening Assays, Humans, Deep Learning, Small Molecule Libraries, Drug Evaluation, Preclinical, Central Nervous System Agents

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2654c6n0
https://escholarship.org/content/qt2654c6n0/qt2654c6n0.pdf

المؤلفون: Weber, Whitney C, Streblow, Daniel N, Coffey, Lark L

المصدر: BioDrugs. 38(6)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Emerging Infectious Diseases, Vaccine Related, Infectious Diseases, Vector-Borne Diseases, Prevention, Arthritis, Biodefense, Biotechnology, Rare Diseases, Immunization, Orphan Drug, 3.4 Vaccines, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Humans, Chikungunya Fever, Chikungunya virus, Viral Vaccines, Vaccines, Attenuated, Animals, Vaccines, Virus-Like Particle, Drug Evaluation, Preclinical, Pharmacology and Pharmaceutical Sciences, Immunology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7jh1r3kv
https://escholarship.org/content/qt7jh1r3kv/qt7jh1r3kv.pdf

المؤلفون: Mead, Heather, Valentine, Michael, Yin, Holly, Thompson Iii, George, Keim, Paul, Engelthaler, David, Barker, Bridget

المصدر: Microbiology Spectrum. 12(10)

مصطلحات موضوعية: Coccidioides, Valley Fever, adjunctive agent, antifungal therapy, coccidioidomycosis, fungal infection, sertraline, Fluconazole, Coccidioides, Animals, Coccidioidomycosis, Antifungal Agents, Mice, Drug Therapy, Combination, Small Molecule Libraries, Humans, Microbial Sensitivity Tests, Disease Models, Animal, Drug Repositioning, Female, Drug Evaluation, Preclinical

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3g46z8cv
https://escholarship.org/content/qt3g46z8cv/qt3g46z8cv.pdf

المؤلفون: Kim, Soochi, Ayan, Bugra, Shayan, Mahdis, Rando, Thomas A, Huang, Ngan F

المصدر: Stem Cell Reports. 19(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Bioengineering, Genetics, Regenerative Medicine, Aging, Biotechnology, Musculoskeletal, Humans, Weightlessness, Regeneration, Drug Evaluation, Preclinical, Muscle, Skeletal, Insulin-Like Growth Factor I, Muscle Development, Lab-On-A-Chip Devices, Tissue Engineering, Gene Expression Profiling, aging, atrophy, microgravity, regeneration, skeletal muscle, tissue engineering, transcriptomics, Clinical Sciences, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5f89b2j0
https://escholarship.org/content/qt5f89b2j0/qt5f89b2j0.pdf

المؤلفون: Lujan, Celia, Tyler, Eleanor Jane, Ecker, Simone, Webster, Amy Philomena, Stead, Eleanor Rachel, Martinez-Miguel, Victoria Eugenia, Milligan, Deborah, Garbe, James Charles, Stampfer, Martha Ruskin, Beck, Stephan, Lowe, Robert, Bishop, Cleo Lucinda, Bjedov, Ivana

المصدر: Genome Medicine. 16(1)

مصطلحات موضوعية: Biological Sciences, Genetics, Aging, Biotechnology, 5.1 Pharmaceuticals, Generic health relevance, Good Health and Well Being, Humans, Animals, DNA Methylation, Longevity, Epigenesis, Genetic, Drug Discovery, Cellular Senescence, Drug Evaluation, Preclinical, Drosophila, Cells, Cultured, Sirolimus, Ageing, CellPopAge epigenetic Clock, CpG methylation, Drug discovery, Rapamycin, Senescence, Clinical Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2t5101p4
https://escholarship.org/content/qt2t5101p4/qt2t5101p4.pdf

المؤلفون: Turpin, Rita, Liu, Ruixian, Munne, Pauliina, Peura, Aino, Rannikko, Jenna, Philips, Gino, Boeckx, Bram, Salmelin, Natasha, Hurskainen, Elina, Suleymanova, Ilida, Aung, July, Vuorinen, Elisa, Lehtinen, Laura, Mutka, Minna, Kovanen, Panu, Niinikoski, Laura, Meretoja, Tuomo, Mattson, Johanna, Mustjoki, Satu, Saavalainen, Päivi, Goga, Andrei, Lambrechts, Diether, Pouwels, Jeroen, Hollmén, Maija, Klefström, Juha

المصدر: Journal for ImmunoTherapy of Cancer. 12(4)

مصطلحات موضوعية: Breast Neoplasms, Dendritic Cells, Drug Evaluation, Preclinical, Immunity, Innate, Immunomodulation, Humans, Female, Electron Transport Complex I, Antineoplastic Agents, Breast Neoplasms, Dendritic Cells, Metformin, Tumor Microenvironment, Sulfonamides, Bridged Bicyclo Compounds, Heterocyclic

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0sz2x90w
https://escholarship.org/content/qt0sz2x90w/qt0sz2x90w.pdf

المؤلفون: Khanna, Astha, Oropeza, Beu P, Huang, Ngan F

المصدر: Journal of Biomedical Materials Research Part A. 112(4)

مصطلحات موضوعية: Biological Sciences, Engineering, Biomedical Engineering, Cardiovascular, Bioengineering, Heart Disease, Precision Medicine, Biotechnology, 5.1 Pharmaceuticals, 5.2 Cellular and gene therapies, Generic health relevance, Good Health and Well Being, Humans, Microphysiological Systems, Lab-On-A-Chip Devices, Drug Development, Tissue Engineering, Drug Evaluation, Preclinical, biomaterials, cardiovascular, organ-on-a-chip, organoid, stem cell, Chemical Sciences, Biological sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4482430z
https://escholarship.org/content/qt4482430z/qt4482430z.pdf

المؤلفون: Li J, Huang S, Hu X, Chen J

المصدر: Drug Design, Development and Therapy, Vol Volume 18, Pp 6297-6312 (2024)

مصطلحات موضوعية: pcsk9 inhibitor, health technology assessment, antihyperlipidemic, inclisiran, drug evaluation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.dovepress.com/comprehensive-assessment-of-pcsk9-inhibitors-for-lipid-management-scie-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

URL الوصول: https://doaj.org/article/8a2a2074f20c4f8b92cb9d06dacf5af2

المؤلفون: Kunihiro Iwamoto, Tetsuo Nakabayashi, Akiko Yamaguchi, Yuki Konishi, Momoe Saji, Reiji Yoshimura, Kousuke Kanemoto, Hirofumi Aoki, Masahiko Ando, Norio Ozaki

المصدر: Neuropsychopharmacology Reports, Vol 44, Iss 4, Pp 682-687 (2024)

مصطلحات موضوعية: antiseizure medication, driving performance, drug evaluation, guideline, traffic accident, Therapeutics. Pharmacology, RM1-950, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2574-173X

URL الوصول: https://doaj.org/article/ac7ece52570f44efaa4eac3eb964d224

المؤلفون: Schott, Courtney R, Koehne, Amanda L, Sayles, Leanne C, Young, Elizabeth P, Luck, Cuyler, Yu, Katherine, Lee, Alex G, Breese, Marcus R, Leung, Stanley G, Xu, Hang, Shah, Avanthi Tayi, Liu, Heng-Yi, Spillinger, Aviv, Behroozfard, Inge H, Marini, Kieren D, Dinh, Phuong T, Ventura, María V Pons, Vanderboon, Emma N, Hazard, Florette K, Cho, Soo-Jin, Avedian, Raffi S, Mohler, David G, Zimel, Melissa, Wustrack, Rosanna, Curtis, Christina, Sirota, Marina, Sweet-Cordero, E Alejandro

المصدر: Clinical Cancer Research. 30(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Orphan Drug, Cancer Genomics, Genetics, Pediatric Cancer, Pediatric, Rare Diseases, Human Genome, Biotechnology, 5.1 Pharmaceuticals, Good Health and Well Being, Humans, Animals, Mice, Disease Models, Animal, Drug Evaluation, Preclinical, Xenograft Model Antitumor Assays, Osteosarcoma, Cell Line, Tumor, Bone Neoplasms, Cyclic N-Oxides, Indolizines, Pyridinium Compounds, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0989t1bg
https://escholarship.org/content/qt0989t1bg/qt0989t1bg.pdf

المؤلفون: Babkov, Denis, Eliseeva, Natalya, Adzhienko, Kristina, Bagmetova, Viktoria, Danilov, Dmitry, McReynolds, Cynthia B, Morisseau, Christophe, Hammock, Bruce D, Burmistrov, Vladimir

المصدر: International Journal of Molecular Sciences. 25(16)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Microbiology, Diabetes, Peripheral Neuropathy, Neurodegenerative, Chronic Pain, Pain Research, Neurosciences, 5.1 Pharmaceuticals, Neurological, Epoxide Hydrolases, Animals, Neuralgia, Male, Mice, Analgesics, Hyperalgesia, Disease Models, Animal, Enzyme Inhibitors, Diabetic Neuropathies, Urea, Drug Evaluation, Preclinical, Edema, Rats, Adamantane, soluble epoxide hydrolase, inhibitor, urea, adamantane, preclinical evaluation, Other Chemical Sciences, Genetics, Other Biological Sciences, Chemical Physics, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5620423h
https://escholarship.org/content/qt5620423h/qt5620423h.pdf

المؤلفون: Zhou, Guangfeng, Rusnac, Domnita-Valeria, Park, Hahnbeom, Canzani, Daniele, Nguyen, Hai Minh, Stewart, Lance, Bush, Matthew F, Nguyen, Phuong Tran, Wulff, Heike, Yarov-Yarovoy, Vladimir, Zheng, Ning, DiMaio, Frank

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Theory Of Computation, Medicinal and Biomolecular Chemistry, Chemical Sciences, Built Environment and Design, Information and Computing Sciences, Design, Networking and Information Technology R&D (NITRD), Machine Learning and Artificial Intelligence, 5.1 Pharmaceuticals, Cancer, Drug Discovery, Humans, Molecular Docking Simulation, Artificial Intelligence, NAV1.7 Voltage-Gated Sodium Channel, Protein Binding, Crystallography, X-Ray, Ligands, Ubiquitin-Protein Ligases, Small Molecule Libraries, Drug Evaluation, Preclinical

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4n56t32w
https://escholarship.org/content/qt4n56t32w/qt4n56t32w.pdf

المؤلفون: Lara C. Pullen, Nick Bott, Cate McCanless, Amee Revana, Gunes Sevinc, Casey Gorman, Alexandra Duncan, Sarah Poliquin, Anna C. Pfalzer, Katie Q. Schmidt, E. Robert Wassman, Chère Chapman, Maria Picone

المصدر: Clocks & Sleep, Vol 6, Iss 4, Pp 656-667 (2024)

مصطلحات موضوعية: clinical trials, drug evaluation, patient care, rare diseases, sleep disorders, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2624-5175/6/4/44; https://doaj.org/toc/2624-5175

URL الوصول: https://doaj.org/article/07f51b10a0b9487a8f89019e5b5c0b1e

المؤلفون: Arang, Nadia, Lubrano, Simone, Ceribelli, Michele, Rigiracciolo, Damiano C, Saddawi-Konefka, Robert, Faraji, Farhoud, Ramirez, Sydney I, Kim, Daehwan, Tosto, Frances A, Stevenson, Erica, Zhou, Yuan, Wang, Zhiyong, Bogomolovas, Julius, Molinolo, Alfredo A, Swaney, Danielle L, Krogan, Nevan J, Yang, Jing, Coma, Silvia, Pachter, Jonathan A, Aplin, Andrew E, Alessi, Dario R, Thomas, Craig J, Gutkind, J Silvio

المصدر: Cell Reports Medicine. 4(11)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Research, Cancer, Eye Disease and Disorders of Vision, Rare Diseases, 5.1 Pharmaceuticals, 2.1 Biological and endogenous factors, Good Health and Well Being, Animals, Mice, Melanoma, Skin Neoplasms, GTP-Binding Protein alpha Subunits, GTP-Binding Protein alpha Subunits, Gq-G11, Drug Evaluation, Preclinical, Uveal Neoplasms, Protein Kinase Inhibitors, FAK, GNAQ, PKC, PKN/PRK, chemogenetic drug screening, combination therapy, melanoma, precision medicine, synthetic lethality, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4vn8x8b7
https://escholarship.org/content/qt4vn8x8b7/qt4vn8x8b7.pdf

المؤلفون: Griffin, Katherine H, Thorpe, Steven W, Sebastian, Aimy, Hum, Nicholas R, Coonan, Thomas P, Sagheb, Isabel S, Loots, Gabriela G, Randall, R Lor, Leach, J Kent

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 120(39)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Engineering, Oncology and Carcinogenesis, Biomedical Engineering, Orphan Drug, Pediatric Cancer, Pediatric, Rare Diseases, Cancer, 2.1 Biological and endogenous factors, Adolescent, Child, Humans, Animals, Mice, Early Detection of Cancer, Bone Marrow, Drug Evaluation, Preclinical, Osteosarcoma, Bone Neoplasms, osteosarcoma, cancer, model, tumorigenesis, bone marrow

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5h50c984
https://escholarship.org/content/qt5h50c984/qt5h50c984.pdf

المؤلفون: Hofmeyer, Mark, Haas, Garrie, Jordan, Elizabeth, Cao, Jinwen, Kransdorf, Evan, Ewald, Gregory, Morris, Alanna, Owens, Anjali, Lowes, Brian, Stoller, Douglas, Wilson Tang, W, Garg, Sonia, Trachtenberg, Barry, Shah, Palak, Pamboukian, Salpy, Sweitzer, Nancy, Wheeler, Matthew, Wilcox, Jane, Katz, Stuart, Pan, Stephen, Jimenez, Javier, Smart, Frank, Wang, Jessica, Gottlieb, Stephen, Judge, Daniel, Moore, Charles, Huggins, Gordon, Kinnamon, Daniel, Ni, Hanyu, Hershberger, Ray

المصدر: Circulation. 148(11)

مصطلحات موضوعية: cardiomyopathy, dilated, genetics, risk, Female, Humans, Male, Middle Aged, Black People, Cardiomyopathy, Dilated, Defibrillators, Implantable, Drug Evaluation, Precision Medicine, Adult, Aged, White, Black or African American, United States

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/98m6v117
https://escholarship.org/content/qt98m6v117/qt98m6v117.pdf

المؤلفون: Nguyen, Khoa, DePledge, Lisa, Bian, Li, Ke, Yao, Samedi, Von, Berning, Amber, Owens, Philip, Wang, Xiao-Jing, Young, Christian

المصدر: Journal for ImmunoTherapy of Cancer. 11(9)

مصطلحات موضوعية: drug evaluation, preclinical, head and neck neoplasms, myeloid-derived suppressor cells, tumor microenvironment, Humans, Animals, Mice, Phosphatidylinositol 3-Kinase, Myeloid-Derived Suppressor Cells, Tobacco, Carcinoma, Squamous Cell, Mouth Neoplasms, Carcinogenesis, Carcinogens, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Phosphatidylinositols

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8bv6609v
https://escholarship.org/content/qt8bv6609v/qt8bv6609v.pdf