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1Academic Journal
المؤلفون: Megan Stiles, Hui Qi, Eleanor Sun, Jeremy Tan, Hunter Porter, Jeremy Allegood, Charles E. Chalfant, Douglas Yasumura, Michael T. Matthes, Matthew M. LaVail, Nawajes A. Mandal
المصدر: Journal of Lipid Research, Vol 57, Iss 5, Pp 818-831 (2016)
مصطلحات موضوعية: retina, P23H line 1 rats, photoreceptors, apoptosis, ceramide, hexosyl-ceramide, Biochemistry, QD415-436
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Anton Delwig, DeLaine D Larsen, Douglas Yasumura, Cindy F Yang, Nirao M Shah, David R Copenhagen
المصدر: PLoS ONE, Vol 11, Iss 2, p e0149501 (2016)
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Douglas Vollrath, Douglas Yasumura, Gillie Benchorin, Michael T Matthes, Wei Feng, Natalie M Nguyen, Cecilia D Sedano, Melissa A Calton, Matthew M LaVail
المصدر: PLoS Genetics, Vol 11, Iss 12, p e1005723 (2015)
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: Mei Li, Douglas Yasumura, Aye Aye K Ma, Michael T Matthes, Haidong Yang, Gregory Nielson, Yong Huang, Francis C Szoka, Matthew M Lavail, Marc I Diamond
المصدر: PLoS ONE, Vol 8, Iss 2, p e56026 (2013)
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Jonathan H. Lin, Cell Biology, Han Li, Douglas Yasumura, Hannah R. Cohen, Chao Zhang, Barbara Panning, Kevan M. Shokat, Matthew M. Lavail, Peter Walter
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.157.5786; http://walterlab.ucsf.edu/Site/pdf/2000-present/lin_science2007.pdf
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6Academic Journal
المؤلفون: Jacque L Duncan, Matthew M Lavail, Douglas Yasumura, Michael T Matthes, Haidong Yang, Nikolaus Trautmann, Aimee V Chappelow, Wei Feng, H Shelton Earp, Glenn K Matsushima, Douglas Vollrath
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1050.1599; http://iovs.arvojournals.org/data/Journals/IOVS/932919/7g0203000826.pdf
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7
المؤلفون: Douglas Yasumura, Jacque L. Duncan, Matthew M. LaVail, Haidong Yang, Robert J. Lowe, Kate M. Daniello, Michael T. Matthes
المصدر: Experimental eye research. 187
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, medicine.medical_specialty, Rhodopsin, genetic structures, Transgene, Mutant, Retina, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Internal medicine, medicine, Electroretinography, Animals, Rats, Long-Evans, Outer nuclear layer, biology, Eye Color, Chemistry, Retinal Degeneration, medicine.disease, Eye pigmentation, eye diseases, Sensory Systems, Rats, Ophthalmology, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Phenotype, Mutation, 030221 ophthalmology & optometry, biology.protein, sense organs, Rats, Transgenic, Transgenic Rats, Erg, Photoreceptor Cells, Vertebrate
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8
المؤلفون: Michael T. Matthes, Matthew M. LaVail, Douglas Yasumura, Eleanor Sun, Jeremy C. Allegood, Hui Qi, Nawajes A Mandal, Charles E. Chalfant, Megan Stiles, Hunter Porter, Jeremy Tan
المصدر: Journal of Lipid Research, Vol 57, Iss 5, Pp 818-831 (2016)
Journal of lipid research, vol 57, iss 5مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, FTY720, retina, Drug Evaluation, Preclinical, Neurodegenerative, Medical Biochemistry and Metabolomics, Bioinformatics, Eye, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Endocrinology, 2.1 Biological and endogenous factors, Aetiology, Research Articles, apoptosis, photoreceptors, Preclinical, Cell biology, medicine.anatomical_structure, Sphingomyelin Phosphodiesterase, 5.1 Pharmaceuticals, Disease Progression, Development of treatments and therapeutic interventions, Sphingomyelin, Photoreceptor Cells, Vertebrate, Programmed cell death, Ceramide, Biochemistry & Molecular Biology, hexosyl-ceramide, QD415-436, Biology, sphingomyelin, 03 medical and health sciences, P23H line 1 rats, Genetic model, Retinal Dystrophies, medicine, Animals, Photoreceptor Cells, ceramide, fingolimod, sphingomyelinase, Eye Disease and Disorders of Vision, Retina, Sphingolipids, Vertebrate, Fingolimod Hydrochloride, Neurosciences, Retinal, Cell Biology, medicine.disease, Sphingolipid, Rats, Biosynthetic Pathways, 030104 developmental biology, chemistry, Drug Evaluation, Sprague-Dawley, Biochemistry and Cell Biology, sense organs
وصف الملف: application/pdf
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9
المؤلفون: Michael T. Matthes, Ward M. Peterson, Nikolaus Trautmann, Haidong Yang, Matthew M. LaVail, Douglas Yasumura, Jeannie Chen, Shimpei Nishikawa, John G. Flannery, Jacque L. Duncan, Cathy Lau-Villacorta, Muna I. Naash, Roy H. Steinberg
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Opsin, genetic structures, Mutant, Neurodegenerative, Medical Biochemistry and Metabolomics, Eye, Ophthalmology & Optometry, Polymerase Chain Reaction, Transgenic, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, 2.1 Biological and endogenous factors, Aetiology, Genetics, Microscopy, Retinal Degeneration, Sensory Systems, Cell biology, Retinitis pigmentosa, medicine.anatomical_structure, Phenotype, Rhodopsin, Rats, Transgenic, Photoreceptor Cells, Vertebrate, Disc shedding, Biology, Electron, Article, Retina, 03 medical and health sciences, Cellular and Molecular Neuroscience, S334ter, Opthalmology and Optometry, medicine, Electroretinography, P23H, Animals, Point Mutation, Photoreceptor Cells, Animal model, Eye Disease and Disorders of Vision, Animal, Vertebrate, Neurosciences, Retinal, medicine.disease, Rats, Ophthalmology, Disease Models, Animal, Microscopy, Electron, 030104 developmental biology, chemistry, Disease Models, biology.protein, Rat, sense organs, Sprague-Dawley, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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10
المؤلفون: Sanford L. Boye, Gavin W. Roddy, Matthew M. LaVail, Robert H. Rosa, Michael T. Matthes, Michael P. Fautsch, Douglas Yasumura, Marcel V. Alavi, William W. Hauswirth
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Stanniocalcin-1, Neurodegenerative, Medical Biochemistry and Metabolomics, Eye, Ophthalmology & Optometry, Transgenic, chemistry.chemical_compound, 0302 clinical medicine, 2.1 Biological and endogenous factors, Aetiology, Gene therapy of the human retina, medicine.diagnostic_test, Gene Therapy, Dependovirus, Sensory Systems, Neuroprotection, medicine.anatomical_structure, Neuroprotective Agents, Retinal ganglion cell, Rats, Transgenic, Erg, Retinitis Pigmentosa, Photoreceptor Cells, Vertebrate, Biotechnology, medicine.medical_specialty, Rhodopsin, Biology, Article, Andrology, 03 medical and health sciences, Cellular and Molecular Neuroscience, S334ter, Opthalmology and Optometry, Ophthalmology, Retinitis pigmentosa, medicine, Electroretinography, P23H, Genetics, Animals, Photoreceptor Cells, Eye Disease and Disorders of Vision, Glycoproteins, Animal, Vertebrate, Neurosciences, Retinal, Macular degeneration, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, chemistry, Disease Models, 030221 ophthalmology & optometry, sense organs
وصف الملف: application/pdf
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11
المؤلفون: Michael Snyder, Marcia Lloyd, Michael T. Matthes, Matthew M. LaVail, Dean Bok, Douglas Vollrath, Douglas Yasumura, Xiyan Li, Chen Zhao, Joshua L. Dunaief, Gregory Nielsen, Kelly Ahern
المصدر: Journal of Clinical Investigation. 121:369-383
مصطلحات موضوعية: Male, Retinal degeneration, Programmed cell death, Cell Survival, Mice, Transgenic, Retinal Pigment Epithelium, Biology, Oxidative Phosphorylation, Mice, chemistry.chemical_compound, Cell Movement, Autophagy, medicine, Animals, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, Retina, Retinal pigment epithelium, Cell Death, Hepatocyte Growth Factor, TOR Serine-Threonine Kinases, Retinal Degeneration, Retinal, Hypertrophy, General Medicine, Cell Dedifferentiation, Proto-Oncogene Proteins c-met, medicine.disease, eye diseases, Cell biology, medicine.anatomical_structure, chemistry, Female, sense organs, Glycolysis, Proto-Oncogene Proteins c-akt, Photoreceptor Cells, Vertebrate, Signal Transduction, Research Article, medicine.drug
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12
المؤلفون: Michael T. Matthes, Douglas Yasumura, Mark E. Pennesi, Shimpei Nishikawa, Matthew M. LaVail
المصدر: Experimental Eye Research. 87:561-570
مصطلحات موضوعية: Retinal degeneration, Aging, Rhodopsin, genetic structures, Retinal Pigment Epithelium, Biology, Article, Photoreceptor cell, Rats, Sprague-Dawley, Neovascularization, Cellular and Molecular Neuroscience, chemistry.chemical_compound, medicine, Animals, Retina, Retinal pigment epithelium, Neovascularization, Pathologic, Retinal Degeneration, Retinal Vessels, Retinal, Anatomy, Rod Cell Outer Segment, medicine.disease, eye diseases, Sensory Systems, Rats, Cell biology, Oxygen tension, Ophthalmology, medicine.anatomical_structure, chemistry, Mutation, biology.protein, sense organs, Rats, Transgenic, medicine.symptom, Photoreceptor Cells, Vertebrate
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13
المؤلفون: Douglas Yasumura, David R. Copenhagen, Anton Delwig, Nirao M. Shah, Cindy F. Yang, DeLaine D. Larsen
المساهمون: Badea, Tudor C
المصدر: PloS one, vol 11, iss 2
PLoS ONE, Vol 11, Iss 2, p e0149501 (2016)
Delwig, A; Larsen, DD; Yasumura, D; Yang, CF; Shah, NM; & Copenhagen, DR. (2016). Retinofugal Projections from Melanopsin-Expressing Retinal Ganglion Cells Revealed by Intraocular Injections of Cre-Dependent Virus. PLOS ONE, 11(2). doi: 10.1371/journal.pone.0149501. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/70s504xr
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Retinal Ganglion Cells, Physiology, Sensory Physiology, lcsh:Medicine, Eye, Inbred C57BL, Mice, 0302 clinical medicine, Thalamus, Arcuate Nucleus, Animal Cells, Genes, Reporter, Medicine and Health Sciences, lcsh:Science, Neurons, Basal forebrain, Multidisciplinary, Suprachiasmatic nucleus, Intraocular, Brain, Dependovirus, Amygdala, Sensory Systems, Isoenzymes, medicine.anatomical_structure, Auditory System, Thalamic Nuclei, Neurological, Zona incerta, Suprachiasmatic Nucleus, Anatomy, Cellular Types, Injections, Intraocular, Research Article, Melanopsin, medicine.medical_specialty, Ganglion Cells, General Science & Technology, 1.1 Normal biological development and functioning, Ocular Anatomy, Hypothalamus, Biology, GPI-Linked Proteins, Retinal ganglion, Retina, Injections, Midbrain, 03 medical and health sciences, Underpinning research, Ocular System, Internal medicine, medicine, Animals, Humans, Eye Disease and Disorders of Vision, Reporter, Auditory Pathway, Integrases, lcsh:R, Neurosciences, Rod Opsins, Biology and Life Sciences, Afferent Neurons, Cell Biology, Alkaline Phosphatase, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Genes, Eyes, lcsh:Q, Neuroscience, Head, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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14
المؤلفون: Kevan M. Shokat, Han Li, Barbara Panning, Jonathan H. Lin, Douglas Yasumura, Peter Walter, Chao Zhang, Hannah R. Cohen, Matthew M. LaVail
المصدر: Science. 318:944-949
مصطلحات موضوعية: Protein Folding, Rhodopsin, endocrine system, Cell Survival, Apoptosis, Protein Serine-Threonine Kinases, Cell fate determination, Endoplasmic Reticulum, Article, Retina, Cell Line, Animals, Genetically Modified, Mice, eIF-2 Kinase, Endoribonucleases, Animals, Humans, EIF-2 kinase, Multidisciplinary, biology, ATF6, Endoplasmic reticulum, Membrane Proteins, Proteins, Activating Transcription Factor 6, Rats, Cell biology, Disease Models, Animal, Kinetics, Cell culture, Mutation, Unfolded protein response, biology.protein, Signal transduction, Retinitis Pigmentosa, Signal Transduction
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15
المؤلفون: Melissa A. Calton, Gillie Benchorin, Wei Feng, Douglas Vollrath, Matthew M. LaVail, Michael T. Matthes, Douglas Yasumura, Natalie M. Nguyen, Cecilia D. Sedano
المساهمون: Hamilton, Bruce A
المصدر: PLoS Genetics
PLoS genetics, vol 11, iss 12
PLoS Genetics, Vol 11, Iss 12, p e1005723 (2015)مصطلحات موضوعية: Retinal degeneration, Cancer Research, lcsh:QH426-470, Knockout, Retinal Pigment Epithelium, Neurodegenerative, Biology, C-Mer Tyrosine Kinase, Eye, Retina, chemistry.chemical_compound, Mice, Phagocytosis, Proto-Oncogene Proteins, medicine, Genetics, 2.1 Biological and endogenous factors, Animals, Humans, Photoreceptor Cells, Aetiology, Allele, Eye Disease and Disorders of Vision, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, Mice, Knockout, Retinal pigment epithelium, c-Mer Tyrosine Kinase, Animal, Retinal Degeneration, Neurosciences, Receptor Protein-Tyrosine Kinases, Retinal, MERTK, medicine.disease, Photoreceptor outer segment, Molecular biology, lcsh:Genetics, Disease Models, Animal, medicine.anatomical_structure, chemistry, Disease Models, sense organs, Developmental Biology, Research Article
وصف الملف: application/pdf
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16
المؤلفون: Victory Joseph, Alfred S. Lewin, Michael T. Matthes, Marina S. Gorbatyuk, Matthew M. LaVail, Douglas Yasumura, Kelly Ahern, Wei-Chieh Chiang, Jonathan H. Lin
المصدر: Retinal Degenerative Diseases ISBN: 9783319171203
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Rhodopsin, genetic structures, Cell Survival, Gene Expression, Mice, Transgenic, CHOP, Article, 03 medical and health sciences, Retinal Rod Photoreceptor Cells, Electroretinography, medicine, Animals, Humans, Photopigment, Transgenes, Mice, Knockout, Transcription Factor CHOP, biology, Reverse Transcriptase Polymerase Chain Reaction, Endoplasmic reticulum, Retinal Degeneration, medicine.disease, Molecular biology, eye diseases, 030104 developmental biology, biology.protein, Unfolded protein response, sense organs
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17
المؤلفون: Michael T. Matthes, Douglas Yasumura, William W. Hauswirth, Matthew M. LaVail, Haidong Yang, Douglas Vollrath, Wen-Tao Deng
المصدر: Retinal Degenerative Diseases ISBN: 9783319171203
مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, Genetic enhancement, Retinal Pigment Epithelium, Neurodegenerative, Eye, Medical and Health Sciences, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, 0302 clinical medicine, Phagosomes, Bestrophins, Promoter Regions, Genetic, Phagosome, Mice, Knockout, medicine.diagnostic_test, Retinal Degeneration, Dependovirus, Mutant Strains, Treatment Outcome, medicine.anatomical_structure, medicine.medical_specialty, MERTK, Knockout, Phagocytosis, Genetic Vectors, Biology, Article, Rats, Mutant Strains, Promoter Regions, 03 medical and health sciences, Gene therapy, Genetic, Chloride Channels, General & Internal Medicine, Proto-Oncogene Proteins, Ophthalmology, Genetics, Electroretinography, medicine, Animals, Humans, Eye Proteins, Eye Disease and Disorders of Vision, Retinal pigment epithelium, c-Mer Tyrosine Kinase, Animal, Neurosciences, Receptor Protein-Tyrosine Kinases, Retinal, Genetic Therapy, medicine.disease, eye diseases, Rats, Treatment, Disease Models, Animal, 030104 developmental biology, chemistry, Disease Models, 030221 ophthalmology & optometry, Sprague-Dawley, sense organs
وصف الملف: application/pdf
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18
المؤلفون: Peter Adamson, Michael T. Matthes, Shuling Guo, Sue Freier, Raechel Peralta, Douglas Yasumura, Andrew T. Watt, Matthew M. LaVail, Haidong Yang, Susan F. Murray, Gene Hung, Ali Jazayeri, Michael L. McCaleb, Brett P. Monia
المصدر: Investigative ophthalmology & visual science, vol 56, iss 11
مصطلحات موضوعية: Male, genetic structures, Messenger, Oligonucleotides, Neurodegenerative, Eye, Ophthalmology & Optometry, Medical and Health Sciences, Transgenic, Photoreceptor cell, chemistry.chemical_compound, Macular Degeneration, Mice, adRP, 2.1 Biological and endogenous factors, Aetiology, Gene knockdown, medicine.diagnostic_test, Blotting, allele-specific, Biochemistry and Molecular Biology, Biological Sciences, medicine.anatomical_structure, Rhodopsin, Rats, Transgenic, Western, Erg, antisense, Blotting, Western, Biology, Real-Time Polymerase Chain Reaction, Rare Diseases, Retinitis pigmentosa, Genetics, medicine, Electroretinography, Animals, RNA, Messenger, Outer nuclear layer, Eye Disease and Disorders of Vision, Alleles, Animal, Neurosciences, Retinal, Oligonucleotides, Antisense, medicine.disease, Molecular biology, eye diseases, Rats, Disease Models, Animal, chemistry, Gene Expression Regulation, Disease Models, biology.protein, RNA, sense organs
وصف الملف: application/pdf
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19
المؤلفون: Michael T. Matthes, Douglas Yasumura, Jonathan H. Lin, Marcel V. Alavi, Wei-Chieh Chiang, Douglas B. Gould, Matthew M. LaVail, Heike Kroeger, Takao Iwawaki
المصدر: Investigative ophthalmology & visual science, vol 56, iss 11
Alavi, MV; Chiang, WC; Kroeger, H; Yasumura, D; Matthes, MT; Iwawaki, T; et al.(2015). In vivo visualization of endoplasmic reticulum stress in the retina using the ERAI reporter mouse. Investigative Ophthalmology and Visual Science, 56(11), 6961-6970. doi: 10.1167/iovs.15-16969. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9xx0d1f0مصطلحات موضوعية: Genetically modified mouse, funduscopy, Aging, genetic structures, Transgene, Mice, Transgenic, Biology, Protein Serine-Threonine Kinases, Endoplasmic Reticulum, GFP, Eye, Ophthalmology & Optometry, Polymerase Chain Reaction, Medical and Health Sciences, Retina, Transgenic, Green fluorescent protein, chemistry.chemical_compound, Mice, In vivo, Animals, Longitudinal Studies, Tomography, Eye Disease and Disorders of Vision, Ultrasonography, Endoplasmic reticulum, Tunicamycin, Neurosciences, Membrane Proteins, Biological Sciences, Protein-Serine-Threonine Kinases, Endoplasmic Reticulum Stress, Molecular biology, eye diseases, Ophthalmoscopy, Retinal Cell Biology, chemistry, Optical Coherence, Unfolded protein response, Signal transduction, ER stress, Tomography, Optical Coherence, Signal Transduction
وصف الملف: application/pdf
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20
المؤلفون: Judith A. Coppinger, Michael T. Matthes, Heike Kroeger, Douglas Yasumura, Krzysztof Palczewski, Carissa Messah, Wei Chieh Chiang, Matthew M. LaVail, Jonathan H. Lin, Sanae Sakami
المصدر: Molecular Neurobiology, vol 52, iss 1
Molecular neurobiology, vol 52, iss 1
Chiang, WC; Kroeger, H; Sakami, S; Messah, C; Yasumura, D; Matthes, MT; et al.(2015). Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration. Molecular Neurobiology, 52(1), 679-695. doi: 10.1007/s12035-014-8881-8. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0388f1mtمصطلحات موضوعية: Retinal degeneration, genetic structures, Messenger, Apoptosis, Inbred C57BL, Photoreceptor cell, Unfolded protein response, Mice, 2.1 Biological and endogenous factors, Psychology, Gene Knock-In Techniques, Aetiology, biology, Retinal Degeneration, Endoplasmic Reticulum-Associated Degradation, Protein-Serine-Threonine Kinases, Endoplasmic Reticulum Stress, Cell biology, medicine.anatomical_structure, Neurology, Rhodopsin, Cognitive Sciences, Signal transduction, ER stress, Signal Transduction, Neuroscience (miscellaneous), Protein Serine-Threonine Kinases, Protein degradation, Endoplasmic-reticulum-associated protein degradation, Article, Retina, Cellular and Molecular Neuroscience, medicine, Animals, Immunoprecipitation, Retinal Photoreceptor Cell Inner Segment, RNA, Messenger, Eye Disease and Disorders of Vision, Neurology & Neurosurgery, Endoplasmic reticulum, Ubiquitination, Neurosciences, Membrane Proteins, Newborn, medicine.disease, Mice, Inbred C57BL, Animals, Newborn, Proteolysis, biology.protein, RNA, sense organs, Rod photoreceptor, Transcription Factor CHOP
وصف الملف: application/pdf