المؤلفون: Ngo, Wayne, Peukes, Julia, Baldwin, Alisha, Xue, Zhiwei, Hwang, Sidney, Stickels, Robert, Lin, Zhi, Satpathy, Ansuman, Wells, James, Schekman, Randy, Nogales De La Morena, Evangelina, Doudna, Jennifer

المصدر: Proceedings of the National Academy of Sciences. 122(1)

مصطلحات موضوعية: delivery, genome editing, viral-like particles, Gene Editing, Humans, CRISPR-Cas Systems, Lentivirus, Ribonucleoproteins, HEK293 Cells, CRISPR-Associated Protein 9, Genetic Vectors

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8538g0dt
https://escholarship.org/content/qt8538g0dt/qt8538g0dt.pdf

المؤلفون: Boger, Ron S, Chithrananda, Seyone, Angelopoulos, Anastasios N, Yoon, Peter H, Jordan, Michael I, Doudna, Jennifer A

المصدر: Nature Communications. 16(1)

مصطلحات موضوعية: Information and Computing Sciences, Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Biological Sciences, Proteins, Algorithms, Computational Biology, Protein Conformation, Data Mining, Databases, Protein, Reproducibility of Results

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3br9k1dr
https://escholarship.org/content/qt3br9k1dr/qt3br9k1dr.pdf

المؤلفون: Elliott, Kerryn, Singh, Vinod, Bäckerholm, Alan, Ögren, Linnea, Lindberg, Markus, Soczek, Katarzyna, Hoberg, Emily, Luijts, Tom, Van den Eynden, Jimmy, Falkenberg, Maria, Doudna, Jennifer, Ståhlberg, Anders, Larsson, Erik

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Telomerase, Promoter Regions, Genetic, Humans, Mutation, Ultraviolet Rays, Cell Line, Tumor, Melanoma, DNA Damage, Binding Sites, Neoplasms

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/15p1s5zg
https://escholarship.org/content/qt15p1s5zg/qt15p1s5zg.pdf

المؤلفون: Tuck, Owen T, Adler, Benjamin A, Armbruster, Emily G, Lahiri, Arushi, Hu, Jason J, Zhou, Julia, Pogliano, Joe, Doudna, Jennifer A

المصدر: Cell. 187(24)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, 1.1 Normal biological development and functioning, DNA Helicases, DNA Damage, Bacteriophages, Phylogeny, Escherichia coli, cryo-EM, genome integrity, helicase, immunity, phage defense, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/178372n6
https://escholarship.org/content/qt178372n6/qt178372n6.pdf

المؤلفون: Hamilton, Jennifer R, Chen, Evelyn, Perez, Barbara S, Sandoval Espinoza, Cindy R, Kang, Min Hyung, Trinidad, Marena, Ngo, Wayne, Doudna, Jennifer A

المصدر: Nature Biotechnology. 42(11)

مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, Immunology, Biotechnology, Genetics, Gene Therapy, Bioengineering, 1.1 Normal biological development and functioning, 5.2 Cellular and gene therapies, Generic health relevance, Humans, Animals, Mice, Gene Editing, T-Lymphocytes, CRISPR-Cas Systems, Cell Engineering, Genetic Vectors, Gene Transfer Techniques

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5hs3n5zd
https://escholarship.org/content/qt5hs3n5zd/qt5hs3n5zd.pdf

المؤلفون: Chen, Kai, Han, Hesong, Zhao, Sheng, Xu, Bryant, Yin, Boyan, Lawanprasert, Atip, Trinidad, Marena, Burgstone, Benjamin W, Murthy, Niren, Doudna, Jennifer A

مصطلحات موضوعية: Medical Biotechnology, Biological Sciences, Biomedical and Clinical Sciences, Lung, Gene Therapy, Biotechnology, Nanotechnology, Digestive Diseases, Genetics, Bioengineering, 1.1 Normal biological development and functioning, 5.2 Cellular and gene therapies

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7mv642q6
https://escholarship.org/content/qt7mv642q6/qt7mv642q6.pdf

المؤلفون: Nomburg, Jason, Doherty, Erin E, Price, Nathan, Bellieny-Rabelo, Daniel, Zhu, Yong K, Doudna, Jennifer A

المصدر: Nature. 633(8030)

مصطلحات موضوعية: Biochemistry and Cell Biology, Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Emerging Infectious Diseases, Infectious Diseases, Genetics, Biodefense, Immunization, 1.1 Normal biological development and functioning, 2.2 Factors relating to the physical environment, Generic health relevance, Infection, Animals, Humans, Bacteriophages, Hydrolysis, Immune Evasion, Immunity, Innate, Models, Molecular, Nucleotides, Cyclic, Phosphoric Diester Hydrolases, Protein Folding, Viral Proteins, Virome, Databases, Protein, Host Microbial Interactions, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7fv2s3sn
https://escholarship.org/content/qt7fv2s3sn/qt7fv2s3sn.pdf

المؤلفون: Kliegman, Melinda, Zaghlula, Manar, Abrahamson, Susan, Esensten, Jonathan H, Wilson, Ross, Urnov, Fyodor D, Doudna, Jennifer A

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Orphan Drug, Sickle Cell Disease, Biotechnology, Hematology, Rare Diseases, 5.1 Pharmaceuticals, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6d59f7sv
https://escholarship.org/content/qt6d59f7sv/qt6d59f7sv.pdf

المؤلفون: Zhao, Huaying, Syed, Abdullah M, Khalid, Mir M, Nguyen, Ai, Ciling, Alison, Wu, Di, Yau, Wai-Ming, Srinivasan, Sanjana, Esposito, Dominic, Doudna, Jennifer A, Piszczek, Grzegorz, Ott, Melanie, Schuck, Peter

المصدر: Nucleic Acids Research. 52(11)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Coronaviruses, Infectious Diseases, Emerging Infectious Diseases, 2.1 Biological and endogenous factors, Infection, SARS-CoV-2, Coronavirus Nucleocapsid Proteins, RNA, Viral, Protein Multimerization, Protein Binding, Binding Sites, Ribonucleoproteins, Virus Assembly, Humans, Nucleocapsid Proteins, Models, Molecular, Phosphoproteins, COVID-19, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/98h4w56x
https://escholarship.org/content/qt98h4w56x/qt98h4w56x.pdf

المؤلفون: Eggers, Amy R, Chen, Kai, Soczek, Katarzyna M, Tuck, Owen T, Doherty, Erin E, Xu, Bryant, Trinidad, Marena I, Thornton, Brittney W, Yoon, Peter H, Doudna, Jennifer A

المصدر: Cell. 187(13)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Gene Therapy, Biotechnology, Genetics, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Cancer, Generic health relevance, Humans, Bacterial Proteins, CRISPR-Associated Protein 9, CRISPR-Cas Systems, Cryoelectron Microscopy, DNA, Gene Editing, Geobacillus stearothermophilus, HEK293 Cells, Protein Domains, Genome, Human, Models, Molecular, Protein Structure, Tertiary, Nucleic Acid Conformation, Biocatalysis, Magnesium, CRISPR-Cas, Cas9 engineering, DNA unwinding, GeoCas9, R-loop formation, WED domain, cryo-EM, genome editing, iGeoCas9, magnesium, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0s58c79k
https://escholarship.org/content/qt0s58c79k/qt0s58c79k.pdf

المؤلفون: Enustun, Eray, Armbruster, Emily G, Lee, Jina, Zhang, Sitao, Yee, Brian A, Malukhina, Kseniya, Gu, Yajie, Deep, Amar, Naritomi, Jack T, Liang, Qishan, Aigner, Stefan, Adler, Benjamin A, Cress, Brady F, Doudna, Jennifer A, Chaikeeratisak, Vorrapon, Cleveland, Don W, Ghassemian, Majid, Bintu, Bogdan, Yeo, Gene W, Pogliano, Joe, Corbett, Kevin D

المصدر: Nucleic Acids Research. 52(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Infectious Diseases, 1.1 Normal biological development and functioning, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, Generic health relevance, Infection, Bacteriophages, Cell Nucleus, CRISPR-Cas Systems, Genome, Viral, RNA, Messenger, RNA, Viral, RNA-Binding Proteins, Viral Proteins, Virus Assembly, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4vt1n111
https://escholarship.org/content/qt4vt1n111/qt4vt1n111.pdf

المؤلفون: Morgan, Chase J, Enustun, Eray, Armbruster, Emily G, Birkholz, Erica A, Prichard, Amy, Forman, Taylor, Aindow, Ann, Wannasrichan, Wichanan, Peters, Sela, Inlow, Koe, Shepherd, Isabelle L, Razavilar, Alma, Chaikeeratisak, Vorrapon, Adler, Benjamin A, Cress, Brady F, Doudna, Jennifer A, Pogliano, Kit, Villa, Elizabeth, Corbett, Kevin D, Pogliano, Joe

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 121(19)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, 1.1 Normal biological development and functioning, Generic health relevance, Viral Proteins, Bacteriophages, Protein Transport, Cell Nucleus, Virus Replication, phage, protein trafficking, phage nucleus

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6tk62335
https://escholarship.org/content/qt6tk62335/qt6tk62335.pdf

المؤلفون: Tsuchida, Connor A, Wasko, Kevin M, Hamilton, Jennifer R, Doudna, Jennifer A

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 121(11)

مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, Biotechnology, Genetics, Gene Therapy, 5.2 Cellular and gene therapies, Generic health relevance, Commerce, Gene Editing, Genetic Therapy, RNA, Messenger, Ribonucleoproteins, genome editing, CRISPR-Cas, in vivo delivery, nonviral delivery, targeted delivery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/285865gb
https://escholarship.org/content/qt285865gb/qt285865gb.pdf

المؤلفون: Adler, Benjamin A, Trinidad, Marena I, Bellieny-Rabelo, Daniel, Zhang, Elaine, Karp, Hannah M, Skopintsev, Petr, Thornton, Brittney W, Weissman, Rachel F, Yoon, Peter H, Chen, LinXing, Hessler, Tomas, Eggers, Amy R, Colognori, David, Boger, Ron, Doherty, Erin E, Tsuchida, Connor A, Tran, Ryan V, Hofman, Laura, Shi, Honglue, Wasko, Kevin M, Zhou, Zehan, Xia, Chenglong, Al-Shimary, Muntathar J, Patel, Jaymin R, Thomas, Vienna CJX, Pattali, Rithu, Kan, Matthew J, Vardapetyan, Anna, Yang, Alana, Lahiri, Arushi, Maxwell, Micaela F, Murdock, Andrew G, Ramit, Glenn C, Henderson, Hope R, Calvert, Roland W, Bamert, Rebecca S, Knott, Gavin J, Lapinaite, Audrone, Pausch, Patrick, Cofsky, Joshua C, Sontheimer, Erik J, Wiedenheft, Blake, Fineran, Peter C, Brouns, Stan JJ, Sashital, Dipali G, Thomas, Brian C, Brown, Christopher T, Goltsman, Daniela SA, Barrangou, Rodolphe, Siksnys, Virginius, Banfield, Jillian F, Savage, David F, Doudna, Jennifer A

المصدر: Nucleic Acids Research. 52(D1)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biotechnology, Genetics, Generic health relevance, CRISPR-Cas Systems, Phylogeny, CRISPR-Associated Proteins, Databases, Genetic, Endodeoxyribonucleases, Encyclopedias as Topic, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5ck3v1hw
https://escholarship.org/content/qt5ck3v1hw/qt5ck3v1hw.pdf

المؤلفون: Shulgina, Yekaterina, Trinidad, Marena I, Langeberg, Conner J, Nisonoff, Hunter, Chithrananda, Seyone, Skopintsev, Petr, Nissley, Amos J, Patel, Jaymin, Boger, Ron S, Shi, Honglue, Yoon, Peter H, Doherty, Erin E, Pande, Tara, Iyer, Aditya M, Doudna, Jennifer A, Cate, Jamie HD

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Machine Learning and Artificial Intelligence, Genetics, 1.1 Normal biological development and functioning, Mutation, Escherichia coli, Nucleic Acid Conformation, RNA, RNA, Ribosomal, Ribosomes, Deep Learning

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4qv857ns
https://escholarship.org/content/qt4qv857ns/qt4qv857ns.pdf

المؤلفون: Syed, Abdullah M, Ciling, Alison, Chen, Irene P, Carlson, Christopher R, Adly, Armin N, Martin, Hannah S, Taha, Taha Y, Khalid, Mir M, Price, Nathan, Bouhaddou, Mehdi, Ummadi, Manisha R, Moen, Jack M, Krogan, Nevan J, Morgan, David O, Ott, Melanie, Doudna, Jennifer A

المصدر: PLOS Pathogens. 20(11)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Emerging Infectious Diseases, Coronaviruses, Infectious Diseases, Genetics, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, Infection, SARS-CoV-2, Phosphorylation, Humans, Virus Replication, Evolution, Molecular, COVID-19, Coronavirus Nucleocapsid Proteins, Phosphoproteins, Virus Assembly, Mutation, Vero Cells, Chlorocebus aethiops, Animals, Microbiology, Immunology, Medical Microbiology, Virology, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/62t2562x
https://escholarship.org/content/qt62t2562x/qt62t2562x.pdf

المؤلفون: Chen, Kai, Stahl, Elizabeth C, Kang, Min Hyung, Xu, Bryant, Allen, Ryan, Trinidad, Marena, Doudna, Jennifer A

المصدر: Nature Communications. 15(1)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5xb1z8tw
https://escholarship.org/content/qt5xb1z8tw/qt5xb1z8tw.pdf

المؤلفون: Chen, Kai, Stahl, Elizabeth C, Kang, Min Hyung, Xu, Bryant, Allen, Ryan, Trinidad, Marena, Doudna, Jennifer A

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Medical Biotechnology, Biological Sciences, Biomedical and Clinical Sciences, Neurosciences, Genetics, Biotechnology, Stem Cell Research, Gene Therapy, Bioengineering, 5.1 Pharmaceuticals, 1.1 Normal biological development and functioning, Generic health relevance, Animals, Mice, Humans, Gene Editing, CRISPR-Cas Systems, Ribonucleoproteins, CRISPR-Associated Protein 9, Brain

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/744960jw
https://escholarship.org/content/qt744960jw/qt744960jw.pdf

المؤلفون: Yoon, Peter H, Skopintsev, Petr, Shi, Honglue, Chen, LinXing, Adler, Benjamin A, Al-Shimary, Muntathar, Craig, Rory J, Loi, Kenneth J, DeTurk, Evan C, Li, Zheng, Amerasekera, Jasmine, Trinidad, Marena, Nisonoff, Hunter, Chen, Kai, Lahiri, Arushi, Boger, Ron, Jacobsen, Steve, Banfield, Jillian F, Doudna, Jennifer A

المصدر: Nucleic Acids Research. 51(22)

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Biotechnology, 1.1 Normal biological development and functioning, Bacteria, DNA Transposable Elements, Endonucleases, Prokaryotic Cells, Transposases, Evolution, Molecular, Eukaryotic Cells, Environmental Sciences, Information and Computing Sciences, Developmental Biology, Biological sciences, Chemical sciences, Environmental sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8tf902c3
https://escholarship.org/content/qt8tf902c3/qt8tf902c3.pdf

المؤلفون: Suryawanshi, Rahul K, Taha, Taha Y, McCavitt-Malvido, Maria, Silva, Ines, Khalid, Mir M, Syed, Abdullah M, Chen, Irene P, Saldhi, Prachi, Sreekumar, Bharath, Montano, Mauricio, Foresythe, Kafaya, Tabata, Takako, Kumar, G Renuka, Sotomayor-Gonzalez, Alicia, Servellita, Venice, Gliwa, Amelia, Nguyen, Jenny, Kojima, Noah, Arellanor, Teresa, Bussanich, Aallyah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Wang, Yuzhu, Ghazarian, Sydney, Davis, Gregg, Rodriguez, Diviana, Doudna, Jennifer, Spraggon, Lee, Chiu, Charles Y, Ott, Melanie

المصدر: Emerging Microbes & Infections. 12(2)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Immunology, Biodefense, Infectious Diseases, Coronaviruses, Prevention, Vaccine Related, Immunization, Emerging Infectious Diseases, Coronaviruses Vaccines, Infection, Good Health and Well Being, Humans, SARS-CoV-2, COVID-19, Vaccination, Antigenic Drift and Shift, Breakthrough Infections, Antibodies, Neutralizing, Antibodies, Viral, recombinants, humoral immunity, neutralization, vaccine, Microbiology, Clinical sciences, Epidemiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5d78j63x
https://escholarship.org/content/qt5d78j63x/qt5d78j63x.pdf