المؤلفون: Phylinda L. S. Chan, Ravi Shankar P. Singh, Donna S. Cox, Haihong Shi, Bharat Damle, Timothy Nicholas

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 12, Pp 1897-1910 (2023)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/b476a8db40e94b18a86663a6931272c5

المؤلفون: Frank Schneider, Margaret Bradbury, Thomas A. Baillie, David Stamler, Edward Hellriegel, Donna S. Cox, Pippa S. Loupe, Juha‐Matti Savola, Laura Rabinovich‐Guilatt

المصدر: Clinical and Translational Science, Vol 13, Iss 4, Pp 707-717 (2020)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

URL الوصول: https://doaj.org/article/488fd588e08e462d8e40b79611ffd5c1

المؤلفون: Donna S. Cox, Lien Van Eyck, Sylvester Pawlak, Bruce Beckerman, Carlos Linn, Katherine Ginman, Youliny Thay Cha, Robert R. LaBadie, Haihong Shi, Bharat Damle

المصدر: British Journal of Clinical Pharmacology.

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::db6aee396446ebd80db185930aa2aa47
https://doi.org/10.1111/bcp.15788

المؤلفون: Donald P. Bottaro, Ronnie T.P. Poon, Lone Harild Ottesen, Howard Kallender, Diptee A. Kulkarni, Kristen E. Raffensperger, Yuan Liu, Robert C. Gagnon, Donna S. Cox, Aaron Camp, Theeranun Sanpajit, Pei-Jer Chen, Wirote Lausoontornsiri, Chia-Jui Yen, Yee Chao, Wattana Sukeepaisarnjaroen, Riccardo Lencioni, Thomas C.C. Yau

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd1825e834816ea73536b314c3936e9
https://doi.org/10.1158/1078-0432.22466073.v1

المؤلفون: Donald P. Bottaro, Ronnie T.P. Poon, Lone Harild Ottesen, Howard Kallender, Diptee A. Kulkarni, Kristen E. Raffensperger, Yuan Liu, Robert C. Gagnon, Donna S. Cox, Aaron Camp, Theeranun Sanpajit, Pei-Jer Chen, Wirote Lausoontornsiri, Chia-Jui Yen, Yee Chao, Wattana Sukeepaisarnjaroen, Riccardo Lencioni, Thomas C.C. Yau

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd95dc8c9a5274b26a5becd46455754
https://doi.org/10.1158/1078-0432.c.6526233

المؤلفون: Donald P. Bottaro, Ronnie T.P. Poon, Lone Harild Ottesen, Howard Kallender, Diptee A. Kulkarni, Kristen E. Raffensperger, Yuan Liu, Robert C. Gagnon, Donna S. Cox, Aaron Camp, Theeranun Sanpajit, Pei-Jer Chen, Wirote Lausoontornsiri, Chia-Jui Yen, Yee Chao, Wattana Sukeepaisarnjaroen, Riccardo Lencioni, Thomas C.C. Yau

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c16b04d0a46f6015be121524d955e0
https://doi.org/10.1158/1078-0432.22466070

المؤلفون: Roy Fleischmann, Wassim Saikali, Sharad Lakhanpal, Daniel F. Alvarez, Donna S. Cox, Claudia Ana Ianos, Wuyan Zhang, Carol Cronenberger, Karen Wang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::414b567e8543ac27c35a839fcb389fa8
https://doi.org/10.2139/ssrn.4337374

المؤلفون: Daniel F. Alvarez, Amy E. Bock, Carol Cronenberger, Donna S. Cox

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Injections, Subcutaneous, Urology, Pharmaceutical Science, Original Manuscript, Bioequivalence, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Adalimumab, medicine, Distribution (pharmacology), Humans, Pharmacology (medical), Dosing, Adverse effect, Biosimilar Pharmaceuticals, bioequivalence, business.industry, Syringes, PF‐06410293, Articles, Middle Aged, Confidence interval, Healthy Volunteers, Injection Site Reaction, Tolerability, 030220 oncology & carcinogenesis, Female, business, pharmacokinetics, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b9a3db92320f28eedc549db2b87384
http://europepmc.org/articles/PMC8518774

المؤلفون: Edward T. Hellriegel, Mark Forrest Gordon, David Stamler, Margaret Bradbury, Pippa S. Loupe, Donna S. Cox, Laura Rabinovich-Guilatt, Frank Schneider, Juha-Matti Savola

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, tetrabenazine, Tetrabenazine, Cmax, Biological Availability, Pharmaceutical Science, Original Manuscript, Pharmacology, Tardive dyskinesia, 030226 pharmacology & pharmacy, Food-Drug Interactions, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, medicine, Humans, Pharmacology (medical), Active metabolite, deuteration, Cross-Over Studies, Adrenergic Uptake Inhibitors, Dose-Response Relationship, Drug, CYP2D6, business.industry, deutetrabenazine, Articles, medicine.disease, Crossover study, Bioavailability, Deutetrabenazine, Area Under Curve, Vesicular Monoamine Transport Proteins, 030220 oncology & carcinogenesis, Female, business, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54d6898ca61ef367ef6156dbacbd254
https://doi.org/10.1002/cpdd.882

المؤلفون: Jill Fiedler-Kelly, Micha Levi, Julie A. Passarell, Margaret Garin, Mary Bond, David Jaworowicz, Laura Rabinovich-Guilatt, Elizabeth Ludwig, Donna S. Cox

المصدر: Journal of clinical pharmacologyReferences. 60(8)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Population, Muscle disorder, Antibodies, Monoclonal, Humanized, 030226 pharmacology & pharmacy, Gastroenterology, Models, Biological, Drug Administration Schedule, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Reslizumab, Pharmacokinetics, Muscular Diseases, Internal medicine, Forced Expiratory Volume, Medicine, Humans, Pharmacology (medical), Computer Simulation, Dosing, Anti-Asthmatic Agents, education, Child, Asthma, Aged, Pharmacology, education.field_of_study, Clinical Trials as Topic, Dose-Response Relationship, Drug, business.industry, Body Weight, Bayes Theorem, Middle Aged, medicine.disease, Eosinophils, 030220 oncology & carcinogenesis, Pharmacodynamics, Administration, Intravenous, Female, Liver function, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09ceba2b6f9066591639e0cee1c3259
https://pubmed.ncbi.nlm.nih.gov/32333684

المؤلفون: David Stamler, Laura Rabinovich-Guilatt, Margaret Bradbury, Juha‐Matti Savola, Donna S. Cox, Edward T. Hellriegel, Frank Schneider, Pippa S. Loupe, Thomas A. Baillie

المصدر: Clinical and Translational Science
Clinical and Translational Science, Vol 13, Iss 4, Pp 707-717 (2020)

مصطلحات موضوعية: Adult, Male, 030213 general clinical medicine, Adolescent, Metabolite, Tetrabenazine, Cmax, Administration, Oral, Pharmacology, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Pharmacokinetics, medicine, Humans, Tardive Dyskinesia, General Pharmacology, Toxicology and Pharmaceutics, Active metabolite, Cross-Over Studies, Adrenergic Uptake Inhibitors, lcsh:Public aspects of medicine, General Neuroscience, Research, lcsh:RM1-950, lcsh:RA1-1270, General Medicine, Articles, Healthy Volunteers, lcsh:Therapeutics. Pharmacology, Huntington Disease, chemistry, Tolerability, Deutetrabenazine, Area Under Curve, Female, Deuterated drug, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d05842b731f54f03b50832c621de28
https://pubmed.ncbi.nlm.nih.gov/32155315

المؤلفون: James M. Foran, Yuehui Wu, Paul Wissel, Yuan Liu, Rebecca L. Olin, Azra Raza, Uwe Platzbecker, Dan Schramek, Elias Jabbour, Michael Boyiadzis, Hagop M. Kantarjian, Norbert Vey, Donna S. Cox, Guillermo Garcia-Manero, Aristoteles Giagounidis, John W. Bauman, Leslie Popplewell, Gautam Borthakur, Tapan M. Kadia, Aref Al-Kali, Roland B. Walter

المصدر: Cancer. 122:1871-1879

مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Trametinib, Cancer Research, Myeloid, business.industry, Myelodysplastic syndromes, Chronic myelomonocytic leukemia, Myeloid leukemia, medicine.disease, medicine.disease_cause, 03 medical and health sciences, Leukemia, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, hemic and lymphatic diseases, 030220 oncology & carcinogenesis, Immunology, medicine, Cancer research, KRAS, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e996193f766ab14f6e8359fc9f8d22aa
https://doi.org/10.1002/cncr.29986

المؤلفون: Amy E. Bock, Daniel F. Alvarez, Carol Cronenberger, Donna S. Cox

المصدر: Annals of the Rheumatic Diseases. 79:1441.2-1442

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Immunology, Cmax, Bioequivalence, General Biochemistry, Genetics and Molecular Biology, law.invention, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Randomized controlled trial, Pharmacokinetics, law, Internal medicine, Immunology and Allergy, Medicine, media_common.cataloged_instance, Dosing, European union, Adverse effect, media_common, 030203 arthritis & rheumatology, business.industry, 030104 developmental biology, Tolerability, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5dfa04eaad7d4376c84cff020d62a46e
https://doi.org/10.1136/annrheumdis-2020-eular.454

المؤلفون: Bela Rajiv Patel, Howard Kallender, Donna S. Cox, Lone Ottesen, Laurel M. Adams, Rajendra P. Singh

المصدر: The Journal of Clinical Pharmacology. 55:1184-1192

مصطلحات موضوعية: Adult, Male, Carcinoma, Hepatocellular, CYP3A, Population, Antineoplastic Agents, Pharmacology, Models, Biological, Young Adult, chemistry.chemical_compound, Pharmacokinetics, Humans, Medicine, Anilides, Pharmacology (medical), education, Protein Kinase Inhibitors, Aged, Aged, 80 and over, Volume of distribution, education.field_of_study, Cross-Over Studies, business.industry, Liver Neoplasms, Cancer, Foretinib, Middle Aged, medicine.disease, digestive system diseases, Bioavailability, chemistry, Hepatocellular carcinoma, Quinolines, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5693340cd251dd57b0a599c10e658b
https://doi.org/10.1002/jcph.546

المؤلفون: YanYan Zhou, Alicia Allred, Johanna C. Bendell, Howard A. Burris, Michael S. Gordon, Suzanne F. Jones, Donna S. Cox, Keith W. Orford, Jeffrey R. Infante

المصدر: Clinical Pharmacology in Drug Development. 4:287-294

مصطلحات موضوعية: Trametinib, business.industry, MEK inhibitor, Cmax, Pharmaceutical Science, Dabrafenib, Pharmacology, Crossover study, Bioavailability, Pharmacokinetics, Medicine, Pharmacology (medical), business, Adverse effect, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e87769620e990c51bc8f964319efb7e9
https://doi.org/10.1002/cpdd.152

المؤلفون: Michael J. Morris, May Y. K. Ho, Donna S. Cox, John W. Bauman, Keith W. Orford, Carolyn B. Pendry, Jill L. Pirhalla, Royce A. Morrison

المصدر: Xenobiotica. 44:352-368

مصطلحات موضوعية: Male, medicine.medical_specialty, Carcinoma, Hepatocellular, Skin Neoplasms, Pyridones, Health, Toxicology and Mutagenesis, Metabolite, Urinary system, Administration, Oral, Antineoplastic Agents, Pyrimidinones, Absorption (skin), Pharmacology, Toxicology, Biochemistry, Absorption, Excretion, Hydroxylation, chemistry.chemical_compound, Internal medicine, medicine, Animals, Humans, Radiometry, Melanoma, Protein Kinase Inhibitors, Aged, ADME, Trametinib, Dose-Response Relationship, Drug, Chemistry, MEK inhibitor, Liver Neoplasms, General Medicine, Middle Aged, Rats, Endocrinology, Radiopharmaceuticals

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983b177fdac0a58cb87bbccb67abafc4
https://doi.org/10.3109/00498254.2013.831143

المؤلفون: Carolyn Pendry, Patricia LoRusso, Anthony W. Tolcher, Keith Orford, Kyri Papadopoulos, John W. Bauman, Donna S. Cox, Lei Fang, Amita Patnaik, Daniele Ouellet

المصدر: The Journal of Clinical Pharmacology. 53:946-954

مصطلحات موضوعية: Pharmacology, Trametinib, Meal, education.field_of_study, business.industry, MEK inhibitor, Population, Cancer, Absorption (skin), medicine.disease, Bioavailability, Pharmacokinetics, Medicine, Pharmacology (medical), education, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a03bff0633a14d6d47cc9c96cdfd536e
https://doi.org/10.1002/jcph.115

المؤلفون: Jeffrey R. Infante, Amita Patnaik, Ngocdiep T. Le, Kyriakos P. Papadopoulos, Howard A. Burris, Anthony W. Tolcher, Johanna C. Bendell, Kevin M. Bellew, Lon Smith, Joohyun Jennifer Park, Drew W. Rasco, Donna S. Cox, Michael Durante, Suzanne F. Jones

المصدر: European Journal of Cancer. 49:2077-2085

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Neutropenia, Maximum Tolerated Dose, Pyridones, Administration, Oral, Pyrimidinones, Pharmacology, Deoxycytidine, Pharmacokinetics, Neoplasms, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Dosing, Infusions, Intravenous, Aged, Trametinib, Dose-Response Relationship, Drug, business.industry, MEK inhibitor, Middle Aged, medicine.disease, Thrombocytopenia, Gemcitabine, Treatment Outcome, Tolerability, Female, business, Febrile neutropenia, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b212be9ad977a7e1259ec1da81b246
https://doi.org/10.1016/j.ejca.2013.03.020

المؤلفون: Theeranun Sanpajit, Diptee A. Kulkarni, Thomas Yau, Yee Chao, Wattana Sukeepaisarnjaroen, Ronnie T.P. Poon, Yuan Liu, A. Camp, Riccardo Lencioni, Robert C. Gagnon, Pei-Jer Chen, Kristen Raffensperger, Howard Kallender, Donna S. Cox, Wirote Lausoontornsiri, Donald P. Bottaro, Lone Ottesen, Chia Jui Yen

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Cancer Research, Carcinoma, Hepatocellular, Maximum Tolerated Dose, Pharmacology, Biomarkers, Pharmacological, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Internal medicine, Proto-Oncogene Proteins, medicine, Carcinoma, Humans, Anilides, Adverse effect, Aged, business.industry, Interleukin-6, Interleukin-8, Liver Neoplasms, Foretinib, Receptor Protein-Tyrosine Kinases, Middle Aged, Protein-Tyrosine Kinases, Proto-Oncogene Proteins c-met, medicine.disease, Receptor, TIE-2, Vascular Endothelial Growth Factor Receptor-2, Axl Receptor Tyrosine Kinase, Clinical trial, 030104 developmental biology, Tolerability, chemistry, 030220 oncology & carcinogenesis, Pharmacodynamics, Hepatocellular carcinoma, Quinolines, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b72aec41990dec0d9357bcab7e3e151
http://hdl.handle.net/11568/902267

المؤلفون: David R. Gandara, Dan Schramek, Natasha B. Leighl, George R. Blumenschein, Filip Janku, Jaafar Bennouna, Olivia Gardner, Vijay Gopal Reddy Peddareddigari, Frances A. Shepherd, Yuan Liu, Jeffrey R. Infante, Karen L. Reckamp, Jean Pierre Delord, Karen Kelly, Julien Mazieres, G. Zalcman, Donna S. Cox, Yuehui Wu, Bijoyesh Mookerjee, Anthony D'Amelio, Fabrice Barlesi

المصدر: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol 12, iss 3
Gandara, DR; Leighl, N; Delord, JP; Barlesi, F; Bennouna, J; Zalcman, G; et al.(2017). A Phase 1/1b Study Evaluating Trametinib Plus Docetaxel or Pemetrexed in Patients With Advanced Non–Small Cell Lung Cancer. Journal of Thoracic Oncology, 12(3), 556-566. doi: 10.1016/j.jtho.2016.11.2218. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2h2312d9

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Lung Neoplasms, medicine.medical_treatment, Docetaxel, Cardiorespiratory Medicine and Haematology, medicine.disease_cause, NSCLC, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, 80 and over, Non-Small-Cell Lung, Trametinib, Aged, 80 and over, MEK inhibitor, Middle Aged, Prognosis, Survival Rate, Pemetrexed, Tolerability, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Female, Taxoids, KRAS, medicine.drug, Pulmonary and Respiratory Medicine, Adult, medicine.medical_specialty, KRAS mutations, Pyridones, Clinical Sciences, Oncology and Carcinogenesis, and over, Pyrimidinones, Adenocarcinoma, 03 medical and health sciences, Internal medicine, medicine, Humans, Oncology & Carcinogenesis, Lung cancer, neoplasms, Aged, Neoplasm Staging, Chemotherapy, business.industry, Carcinoma, Large Cell, medicine.disease, respiratory tract diseases, 030104 developmental biology, Squamous Cell, Carcinoma, Large Cell, business, Follow-Up Studies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65acbf1632d6e0f19e4fa32f82df26ba
https://pubmed.ncbi.nlm.nih.gov/27876675