المؤلفون: Mariateresa Fulciniti, Zoe Jacobson, Georg E. Winter, Michael A. Erb, Michael A. Lopez, Evon Poon, Donald R. Polaski, Thomas F. Westbrook, Jaime M. Reyes, James E. Bradner, Matthew A. Lawlor, Charles Y. Lin, Rachel A. Hirsch, Rhamy Zeid, Nikhil P. Munshi, Louis Chesler, Behnam Nabet, Kristen L. Karlin, Thomas G. Scott

المصدر: Nature Genetics. 50:515-523

مصطلحات موضوعية: 0301 basic medicine, Genes, myc, Biology, N-Myc Proto-Oncogene Protein, Article, Neuroblastoma, 03 medical and health sciences, Twist transcription factor, Transcription (biology), Cell Line, Tumor, Genetics, medicine, Humans, Promoter Regions, Genetic, Enhancer, neoplasms, Transcription factor, Binding Sites, Twist-Related Protein 1, Gene Amplification, Nuclear Proteins, Promoter, Oncogenes, medicine.disease, Chromatin, Cell biology, Kinetics, Enhancer Elements, Genetic, 030104 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fa9dc6c212cc89df74f448dcc03322
https://doi.org/10.1038/s41588-018-0044-9

المؤلفون: Josephine L. Klitgaard, Siddha Kasar, Deepti Gadi, Donald R. Polaski, Qiyuan Li, Matthew L. Freedman, Alexander J. Federation, Christopher J. Ott, Stacey M. Fernandes, Amanda Souza, James E. Bradner, Romina E. Lenci, Jennifer R. Brown, Matthew A. Lawlor, Logan Schwartz

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Chronic lymphocytic leukemia, Biology, Article, Histones, 03 medical and health sciences, Super-enhancer, Cell Line, Tumor, hemic and lymphatic diseases, Gene expression, medicine, Animals, Humans, Enhancer, Transcription factor, Mice, Knockout, Gene Expression Regulation, Leukemic, PAX5 Transcription Factor, Proteins, Nuclear Proteins, Acetylation, Azepines, Cell Biology, Triazoles, medicine.disease, Xenograft Model Antitumor Assays, Leukemia, Lymphocytic, Chronic, B-Cell, Chromatin, Bromodomain, Cell biology, Enhancer Elements, Genetic, 030104 developmental biology, Oncology, PAX5, Protein Binding, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75dbad923dceb29064f184d31c23aa8
https://europepmc.org/articles/PMC6298230/

المؤلفون: James E. Bradner, Donald R. Polaski, Angela Fan, Christopher J. Ott, Alexander J. Federation, Charles Y. Lin

مصطلحات موضوعية: Regulation of gene expression, Computer science, Systems biology, fungi, genetic processes, Master regulator, Computational biology, Network topology, Transcriptional regulation, natural sciences, Enhancer, Centrality, Transcription factor, Network model

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4199a8a75cdc9425054218803bb2ecc9
https://doi.org/10.1101/345413

المؤلفون: Volker Hovestadt, Peter Lichter, Linlin Yin, Sebastian M. Waszak, Victor V. Chizhikov, Maia Segura-Wang, Donald R. Polaski, Marc Zapatka, Parthiv Haldipur, Marcel Kool, Andrey Korshunov, James E. Bradner, Paul A. Northcott, Roland Eils, David T.W. Jones, Laura Sieber, Lukas Chavez, Bensheng Ju, Wenbiao Chen, Barbara C. Worst, Yiai Tong, Pascal Johann, Hans Lehrach, Rhamy Zeid, Vyacheslav Amstislavskiy, Serap Erkek, Thomas Risch, Ivo Buchhalter, Stefan M. Pfister, Marie-Laure Yaspo, Stefan Gröschel, Brent A. Orr, Daisuke Kawauchi, Jan O. Korbel, Hans-Jörg Warnatz, Kathleen J. Millen, Marina Ryzhova, Charles Y. Lin, Alexander J. Federation

المصدر: Nature

مصطلحات موضوعية: Male, 0301 basic medicine, Gene regulatory network, Biology, Article, Transcriptome, Mice, 03 medical and health sciences, Genes, Reporter, medicine, Animals, Humans, Gene Regulatory Networks, Cerebellar Neoplasms, Enhancer, Transcription factor, Zebrafish, Regulation of gene expression, Medulloblastoma, Genetics, Multidisciplinary, Reproducibility of Results, medicine.disease, Gene Expression Regulation, Neoplastic, Enhancer Elements, Genetic, 030104 developmental biology, DNA methylation, Female, Chromatin immunoprecipitation, Genes, Neoplasm, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88de35f0b25c0c3ecc0f6f80faa329b
https://doi.org/10.1038/nature16546

المؤلفون: Marc Zapatka, Stefan M. Pfister, Marcel Kool, David T.W. Jones, Daisuke Kawauchi, Vyacheslav Amstislavskiy, Parthiv Haldipur, Marie-Laure Yaspo, Bensheng Ju, Paul A. Northcott, Brent A. Orr, Wenbiao Chen, Peter Lichter, Barbara C. Worst, Yiai Tong, Marina Ryzhova, Stefan Gröschel, Laura Sieber, Donald R. Polaski, Kathleen J. Millen, Pascal Johann, Volker Hovestadt, Alexander J. Federation, Serap Erkek, Roland Eils, Jan O. Korbel, Hans Lehrach, Charles Y. Lin, Linlin Yang, Rhamy Zeid, Thomas Risch, Ivo Buchhalter, Andrey Korshunov, Hans-Jörg Warnatz, Sebastian M. Waszak, Victor V. Chizhikov, James E. Bradner, Maia Segura-Wang

المصدر: Molecular Cancer Therapeutics. 14:LB-B23

مصطلحات موضوعية: Medulloblastoma, Genetics, Cancer Research, Oncology, Molecular targets, medicine, Large series, Biology, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7eed4d827a87b1b0dc522baca289af7c
https://doi.org/10.1158/1535-7163.targ-15-lb-b23