المؤلفون: Catherine Z. Chen, Paul Shinn, Zina Itkin, Richard T. Eastman, Robert Bostwick, Lynn Rasmussen, Ruili Huang, Min Shen, Xin Hu, Kelli M. Wilson, Brianna M. Brooks, Hui Guo, Tongan Zhao, Carleen Klump-Thomas, Anton Simeonov, Samuel G. Michael, Donald C. Lo, Matthew D. Hall, Wei Zheng

المصدر: Frontiers in Pharmacology, Vol 11 (2021)

مصطلحات موضوعية: COVID-19, cytopathic effect, drug repurposing and discovery, HTS, SARS-CoV-2, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2020.592737/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/6fdf6eea16ad4d56b94f2a702c53b35f

المؤلفون: Leila Pirhaji, Pamela Milani, Simona Dalin, Brook T. Wassie, Denise E. Dunn, Robert J. Fenster, Julian Avila-Pacheco, Paul Greengard, Clary B. Clish, Myriam Heiman, Donald C. Lo, Ernest Fraenkel

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/ec0af8273fb342fcbf9ccadba0111a01

المؤلفون: Rocio Gomez-Pastor, Eileen T. Burchfiel, Daniel W. Neef, Alex M. Jaeger, Elisa Cabiscol, Spencer U. McKinstry, Argenia Doss, Alejandro Aballay, Donald C. Lo, Sergey S. Akimov, Christopher A. Ross, Cagla Eroglu, Dennis J. Thiele

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/10e213fe581949ff9cd3a516b23f2861

المؤلفون: Melissa G. Christianson, Donald C. Lo

المصدر: Neurobiology of Disease, Vol 77, Iss , Pp 94-105 (2015)

مصطلحات موضوعية: Axonopathy, Axonal degeneration, Axonal transport, Amyloid precursor protein, Amyloid beta, Retinal explant, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996115000662; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/4db5e2a65fba4f2bb19b89589a2bc4a2

المؤلفون: Zhiquan Zhang, Qing Ma, Bijal Shah, G. Burkhard Mackensen, Donald C. Lo, Joseph P. Mathew, Mihai V. Podgoreanu, Niccolò Terrando

المصدر: Frontiers in Immunology, Vol 8 (2017)

مصطلحات موضوعية: memory, neuroinflammation, NF-κB, postoperative cognitive dysfunction, resolution of inflammation, surgery, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2017.01050/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/d3eeb5b8241a48cf9406a74d57507cbf

المؤلفون: Peter H. Reinhart, Linda S. Kaltenbach, Christian Essrich, Denise E. Dunn, Joshua A. Eudailey, C. Todd DeMarco, Gregory J. Turmel, Jennifer C. Whaley, Andrew Wood, Seongeun Cho, Donald C. Lo

المصدر: Neurobiology of Disease, Vol 43, Iss 1, Pp 248-256 (2011)

مصطلحات موضوعية: Adenosine, A2A, JNK, IKK, CXCR3, Microglia, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996111000994; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/f67d6e594ca04498b24c1f147e59e74f

المؤلفون: Steven P. Braithwaite, Ralf S. Schmid, Dong Ning He, Mei-Li A. Sung, Seongeon Cho, Lynn Resnick, Michael M. Monaghan, Warren D. Hirst, Christian Essrich, Peter H. Reinhart, Donald C. Lo

المصدر: Neurobiology of Disease, Vol 39, Iss 3, Pp 311-317 (2010)

مصطلحات موضوعية: JNK, APP, Neurodegeneration, Neuroprotection, Biolistics, Brain slice, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996110001312; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/c0c70fab7042413f92f666c7d531d9d0

المؤلفون: David R. Riddle, Lawrence C. Katz, Donald C. Lo

المصدر: BioTechniques, Vol 23, Iss 5, Pp 928-937 (1997)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

URL الوصول: https://doaj.org/article/31590919ec9d4322841669ef438b5281

المؤلفون: Richard Hargreaves, Karen Akinsanya, Seena K. Ajit, Neel T. Dhruv, Jamie Driscoll, Peter Farina, Narender Gavva, Marie Gill, Andrea Houghton, Smriti Iyengar, Carrie Jones, Annemieke Kavelaars, Ajamete Kaykas, Walter J. Koroshetz, Pascal Laeng, Jennifer M. Laird, Donald C. Lo, Johan Luthman, Gordon Munro, Michael L. Oshinsky, G. Sitta Sittampalam, Sarah A. Woller, Amir P. Tamiz

المصدر: Expert Opinion on Therapeutic Targets. 26:811-822

مصطلحات موضوعية: Pharmacology, Clinical Biochemistry, Drug Discovery, Humans, Pain, Molecular Medicine, Opioid-Related Disorders

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a580423b3a5c4e04c717c45c0b1e987
https://doi.org/10.1080/14728222.2022.2147063

المؤلفون: Lomash, Richa Madan, Shchelochkov, Oleg, Chandler, Randy J., Venditti, Charles P., Pariser, Anne R., Ottinger, Elizabeth A., Gilberto V., Averion, Krishna, Balakrishnan, Carsten G., Bönnemann, Philip J., Brooks, Steven J., Burden, Eggerton, Campbell, Catherine, Chen, Eun-Young, Choi, Claire, Driscoll, Oksana, Dukhanina, Susan, Ferry, A. Reghan, Foley, Janelle Geist, Hauserman, Lina, Li, Donald C., Lo, Venkata, Mangalampalli, Irini, Manoli, Christopher, Mendoza, Julien, Oury, Forbes D., Porter, Deanna, Portero, Lili, Portilla, Jachinta, Rooney, Dimah, Saade, Jennifer L., Sloan, Mitali, Tambe, Pramod, Terse, Joshua, Todd, London, Toney, Carol, Van Ryzin, Rodica, Stan, Sury, Vepa, Erik, Wagner, Amy, Wang, Xin, Xu, Yaqun, Zou

المصدر: Human Gene Therapy ; volume 34, issue 5-6, page 217-227 ; ISSN 1043-0342 1557-7422

الاتاحة: http://dx.doi.org/10.1089/hum.2022.232
https://www.liebertpub.com/doi/full-xml/10.1089/hum.2022.232
https://www.liebertpub.com/doi/pdf/10.1089/hum.2022.232

المؤلفون: Wei Zhu, Donald C. Lo, Zeenat A Shyr, Wei Zheng

المصدر: The Journal of Pharmacology and Experimental Therapeutics

مصطلحات موضوعية: Pharmacology, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), SARS-CoV-2, Viral Proteases, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), viruses, Biology, Virology, Antiviral Agents, COVID-19 Drug Treatment, Drug development, Viral protease, Drug Development, Molecular Medicine, Animals, Humans, Protease Inhibitors, Minireview

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e825855d5b285f91c46e3c4a07b74af7
http://europepmc.org/articles/PMC8686716

المؤلفون: Xiao Lu, Zhiji Luo, Ruili Huang, Donald C. Lo, Wenwei Huang

المصدر: Chemistry – A European Journal. 28

مصطلحات موضوعية: Organic Chemistry, General Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05359426558a75ae782224c6a5ed349
https://doi.org/10.1002/chem.202201421

المؤلفون: Wei Zheng, Donald C. Lo, Wei Zhu, Catherine Z. Chen, Kirill Gorshkov, Miao Xu

المصدر: Slas Discovery

مصطلحات موضوعية: 0301 basic medicine, Drug, Emergency Use Authorization, RdRP inhibitors, viruses, media_common.quotation_subject, 030106 microbiology, RdRP assays, RNA-dependent RNA polymerase, Disease, Biology, Virus Replication, Antiviral Agents, Biochemistry, Article, Analytical Chemistry, coronavirus infection, Viral Proteins, 03 medical and health sciences, chemistry.chemical_compound, RNA polymerase, Drug Discovery, Humans, Enzyme Inhibitors, media_common, chemistry.chemical_classification, Alanine, SARS-CoV-2, Drug discovery, COVID-19, Amides, Virology, Adenosine Monophosphate, High-Throughput Screening Assays, COVID-19 Drug Treatment, 030104 developmental biology, Enzyme, Drug development, chemistry, Pyrazines, Middle East Respiratory Syndrome Coronavirus, Molecular Medicine, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56acf0c925138525078cc51391c98ca2
https://doi.org/10.1177/2472555220942123

المؤلفون: Elizabeth A. Ottinger, Anne Pariser, Philip J. Brooks, Asaf Alimardanov, Christopher P. Austin, Richa Madan Lomash, Eric Esposito, Pramod S. Terse, Carsten G. Bönnemann, Xin Xu, Deanna Portero, Randy J. Chandler, Janelle Geist Hauserman, Charles P. Venditti, Donald C. Lo

المصدر: Human Gene Therapy

مصطلحات موضوعية: Clinical Trials as Topic, business.industry, Genetic enhancement, Genetic Vectors, Genetic Therapy, Dependovirus, medicine.disease_cause, Bioinformatics, Clinical trial, Rare Diseases, Genetics, medicine, Humans, Molecular Medicine, Vector (molecular biology), business, Special Report, Molecular Biology, Gene, Adeno-associated virus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baa4221778a870fb9ecaeeecfde7506
https://doi.org/10.1089/hum.2020.259

المؤلفون: Koning Shen, Barbara Calamini, Jonathan A Fauerbach, Boxue Ma, Sarah H Shahmoradian, Ivana L Serrano Lachapel, Wah Chiu, Donald C Lo, Judith Frydman

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: Huntington's disease, proteostasis, aggregation, Medicine, Science, Biology (General), QH301-705.5

Relation: https://elifesciences.org/articles/18065; https://doaj.org/toc/2050-084X; e18065; https://doaj.org/article/3db1d5e751fe4e55945a6a20452f119f

الاتاحة: https://doi.org/10.7554/eLife.18065
https://doaj.org/article/3db1d5e751fe4e55945a6a20452f119f

المؤلفون: Alyssa M. Klein, Donald C. Lo, Denise E. Dunn, Christopher J. Chang, Divya Venkatesh, David R. Tong, Sung-Hwan Moon, Everett S. Kengmana, Joleen M. Csuka, Brent R. Stockwell, Fereshteh Zandkarimi, Angelo D'Alessandro, Allegra T. Aron, Carol Prives, Nicholas A. O'Brien, Michael E. Stokes, Marcus Conrad

المصدر: Genes & development, vol 34, iss 7-8
Genes Dev

مصطلحات موضوعية: MDMX, Ubiquinone, Mutant, Cell Cycle Proteins, Endogeny, PPARα, Medical and Health Sciences, law.invention, Lipid peroxidation, chemistry.chemical_compound, 0302 clinical medicine, RNA interference, law, lipid metabolism, 2.1 Biological and endogenous factors, Aetiology, 0303 health sciences, biology, Brain, Proto-Oncogene Proteins c-mdm2, Biological Sciences, Cell biology, 030220 oncology & carcinogenesis, Mdm2, RNA Interference, Research Paper, FSP1, 03 medical and health sciences, MDM2, Proto-Oncogene Proteins, Genetics, Animals, Humans, Ferroptosis, cancer, PPAR alpha, CoQ(10), neoplasms, 030304 developmental biology, Prevention, Psychology and Cognitive Sciences, Lipid metabolism, CoQ10, Lipid Metabolism, HCT116 Cells, Rats, enzymes and coenzymes (carbohydrates), chemistry, Mutation, biology.protein, Suppressor, Generic health relevance, Tumor Suppressor Protein p53, Glioblastoma, p53-independent, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6147ac4d6e3ce7d0532f75f736d112a4
https://doi.org/10.1101/gad.334219.119

المؤلفون: Kimberly Malesky, Donald C. Lo, Guizhi Yang, Alice Loo, Hui Gao, Joshua M. Korn, Raymond Pagliarini, Brent R. Stockwell, Fallon Lin, Tom Mikkelsen, Eduard Reznik, Ana C. deCarvalho, Ling F. Ye

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, chemical biology, Biology, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, glioma, Neurosphere, Glioma, Gene expression, medicine, cancer, Drug discovery, RNA, Cancer, medicine.disease, nervous system diseases, 3. Good health, cell death, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e622bca7b5e1967914a420da39d39c8e
https://doi.org/10.18632/oncotarget.27457

المؤلفون: Shawn Hingtgen, Denise E. Dunn, Simon Khagi, Andrew Satterlee, Donald C. Lo

المصدر: Neuro-Oncology

مصطلحات موضوعية: Cancer Research, Combination therapy, medicine.medical_treatment, Mice, Nude, Apoptosis, Biology, Rats, Sprague-Dawley, Mice, Neural Stem Cells, In vivo, Cancer stem cell, Tumor Cells, Cultured, medicine, Animals, Humans, Cell Proliferation, Brain Neoplasms, Editorials, Stem-cell therapy, Xenograft Model Antitumor Assays, Neural stem cell, Rats, Oncology, Cancer cell, Neoplastic Stem Cells, Cancer research, Female, Neurology (clinical), Stem cell, Glioblastoma, Ex vivo, Stem Cell Transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279c54eb5165c7a03674b188ccc30850
https://doi.org/10.1093/neuonc/noz138

المؤلفون: Wei Zheng, Matthew Might, Steven Rodems, Donald C. Lo, Atena Farkhondeh, Rong Li, Kirill Gorshkov, Kevin G. Chen

المصدر: Drug Discovery Today. 24:992-999

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, business.industry, Drug discovery, Induced Pluripotent Stem Cells, Disease, Phenotype, Article, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Human disease, Drug development, 030220 oncology & carcinogenesis, Drug Discovery, Humans, Medicine, Nervous System Diseases, business, Induced pluripotent stem cell, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424e2fac61af852f72e74c327284cb6a
https://doi.org/10.1016/j.drudis.2019.01.007

المؤلفون: Kanny K. Wan, Danielle Davis, Taylor N. Lee, Stephanie L. Ford-Scheimer, Antonio L. Andreu, Florence Bietrix, Justin Bryans, Marco T. Castro, Nobuyoshi Chiba, Jessica M. Faupel-Badger, Brittany Haynes, Ryutaro Hirasawa, Carlos M. Morel, Thiago Moreno L. Souza, David Morrow, Trent Munro, Stuart Newman, Anton E. Ussi, Poliana B. Zorzal, Matthew D. Hall, Donald C. Lo, Christine M. Cutillo

المصدر: Nature Reviews Drug Discovery

مصطلحات موضوعية: Pharmacology, Drug Discovery, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87074b38b5e8f64a8caab0fcae942d91
https://doi.org/10.1038/d41573-022-00020-6