المؤلفون: Thor S. Thorsen, Yashraj Kulkarni, David A. Sykes, Andreas Bøggild, Taner Drace, Pattarin Hompluem, Christos Iliopoulos-Tsoutsouvas, Spyros P. Nikas, Henrik Daver, Alexandros Makriyannis, Poul Nissen, Michael Gajhede, Dmitry B. Veprintsev, Thomas Boesen, Jette S. Kastrup, David E. Gloriam

المصدر: Nature Communications, Vol 16, Iss 1, Pp 1-13 (2025)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/626bd222e009428aaf026567f1c58af3

المؤلفون: Anastasiia Gusach, Yang Lee, Armin Nikpour Khoshgrudi, Elizaveta Mukhaleva, Ning Ma, Eline J. Koers, Qingchao Chen, Patricia C. Edwards, Fanglu Huang, Jonathan Kim, Filippo Mancia, Dmitry B. Veprintsev, Nagarajan Vaidehi, Simone N. Weyand, Christopher G. Tate

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/652fff5f256d4ddc952071804619e0c2

المؤلفون: Sean A. Cullum, Simon Platt, Natasha Dale, Oliver C. Isaac, Edward S. Wragg, Mark Soave, Dmitry B. Veprintsev, Jeanette Woolard, Laura E. Kilpatrick, Stephen J. Hill

المصدر: Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/1c67926d1da64115a6683f7383bac865

المؤلفون: Miroslav Kosar, Roman C. Sarott, David A. Sykes, Alexander E. G. Viray, Rosa Maria Vitale, Nataša Tomašević, Xiaoting Li, Rudolf L. Z. Ganzoni, Bilal Kicin, Lisa Reichert, Kacper J. Patej, Uxía Gómez-Bouzó, Wolfgang Guba, Peter J. McCormick, Tian Hua, Christian W. Gruber, Dmitry B. Veprintsev, James A. Frank, Uwe Grether, Erick M. Carreira

المصدر: ACS Central Science, Vol 10, Iss 5, Pp 956-968 (2024)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/a9641dd9dece4c6580e5b5242c4407b7

المؤلفون: Sara Wong, Alexander D. Brown, Abigail B. Abrahams, An Nisaa Nurzak, Hoda M. Eltaher, David A. Sykes, Dmitry B. Veprintsev, Kevin C. F. Fone, James E. Dixon, Madeleine V. King

المصدر: Pharmaceutics, Vol 16, Iss 10, p 1267 (2024)

مصطلحات موضوعية: insulin, oxytocin, cell-penetrating peptide, glycosaminoglycan-GAG-binding enhanced transduction, RPMI 2650, transcytosis, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/10/1267; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/46e3a3fb62ff4c11b57c91f0106aeaf4

المؤلفون: Morgan Scott-Dennis, Fikri A. Rafani, Yicheng Yi, Themiya Perera, Clare R. Harwood, Wolfgang Guba, Arne C. Rufer, Uwe Grether, Dmitry B. Veprintsev, David A. Sykes

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: G-protein signaling, Gαi signaling pathway, cannabinoid receptors (CBRs), inverse agonism, BRET—bioluminescence resonance energy transfer, GPCR signalling assay, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1158091/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/bd3b602001cb48838825a2f74ab966f7

المؤلفون: Mireia Jiménez‐Rosés, Bradley Angus Morgan, Maria Jimenez Sigstad, Thuy Duong Zoe Tran, Rohini Srivastava, Asuman Bunsuz, Leire Borrega‐Román, Pattarin Hompluem, Sean A. Cullum, Clare R. Harwood, Eline J. Koers, David A. Sykes, Iain B. Styles, Dmitry B. Veprintsev

المصدر: Pharmacology Research & Perspectives, Vol 10, Iss 5, Pp n/a-n/a (2022)

مصطلحات موضوعية: adrenoceptor, docking, drug discovery, GPCRs, machine learning, structure‐activity relationship, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2052-1707

URL الوصول: https://doaj.org/article/8c395ffb80f645bb9233171b8236b0df

المؤلفون: David A. Sykes, Mireia Jiménez‐Rosés, John Reilly, Robin A. Fairhurst, Steven J. Charlton, Dmitry B. Veprintsev

المصدر: Pharmacology Research & Perspectives, Vol 10, Iss 4, Pp n/a-n/a (2022)

مصطلحات موضوعية: adrenergicbeta‐blockers, kinetic selectivity, physicochemical properties, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2052-1707

URL الوصول: https://doaj.org/article/23a0dbaf85364a89ad9273ace3affdf9

المؤلفون: Daniel Mayer, Fred F. Damberger, Mamidi Samarasimhareddy, Miki Feldmueller, Ziva Vuckovic, Tilman Flock, Brian Bauer, Eshita Mutt, Franziska Zosel, Frédéric H. T. Allain, Jörg Standfuss, Gebhard F. X. Schertler, Xavier Deupi, Martha E. Sommer, Mattan Hurevich, Assaf Friedler, Dmitry B. Veprintsev

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/3fb017c511b74ac5b642a4f342d8976b

المؤلفون: Franziska M. Heydenreich, Tamara Miljuš, Rolf Jaussi, Roger Benoit, Dalibor Milić, Dmitry B. Veprintsev

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/1b11ce312b1949debc1d11e568ec22af

المؤلفون: Alexandre Beautrait, Justine S. Paradis, Brandon Zimmerman, Jenna Giubilaro, Ljiljana Nikolajev, Sylvain Armando, Hiroyuki Kobayashi, Lama Yamani, Yoon Namkung, Franziska M. Heydenreich, Etienne Khoury, Martin Audet, Philippe P. Roux, Dmitry B. Veprintsev, Stéphane A. Laporte, Michel Bouvier

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/6eba6ba8e03a459fb317fb0b5ab08460

المؤلفون: Philip Rößler, Daniel Mayer, Ching-Ju Tsai, Dmitry B. Veprintsev, Gebhard F. X. Schertler, Alvar D. Gossert

المصدر: Molecules, Vol 25, Iss 24, p 5984 (2020)

مصطلحات موضوعية: GPCR, nanobody, mini-G, NMR, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/24/5984; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/96d2b623dd234e1ba8de5ea56ecfc1d0

المؤلفون: Dalibor eMilić, Dmitry B. Veprintsev

المصدر: Frontiers in Pharmacology, Vol 6 (2015)

مصطلحات موضوعية: Isotope Labeling, Protein Engineering, Expression, purification, G protein-coupled receptor (GPCR), Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00066/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/e2405b30140e4c0088547880d4df1d4f

المؤلفون: María José Sánchez-Barrena, Yvonne Vallis, Menna R. Clatworthy, Gary J. Doherty, Dmitry B. Veprintsev, Philip R. Evans, Harvey T. McMahon

المصدر: PLoS ONE, Vol 8, Iss 8 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3738646; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/4ceadbf389ff419297d5c6803dbe407e

المؤلفون: Sean A. Cullum, Dmitry B. Veprintsev, Stephen J. Hill

المصدر: British Journal of Pharmacology. 180:1304-1315

مصطلحات موضوعية: Pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2dfeaaf74e019acb6f8492318ce4c828
https://doi.org/10.1111/bph.16008

المؤلفون: Michel Bouvier, Franziska M. Heydenreich, Christian Munk, David E. Gloriam, M. Madan Babu, Albert J. Kooistra, Dmitry B. Veprintsev, Alexander S. Hauser

المصدر: Nature Structural & Molecular Biology
Hauser, A S, Kooistra, A J, Munk, C, Heydenreich, F M, Veprintsev, D B, Bouvier, M, Babu, M M & Gloriam, D E 2021, ' GPCR activation mechanisms across classes and macro/microscales ', Nature Structural and Molecular Biology, vol. 28, no. 11, pp. 879-888 . https://doi.org/10.1038/s41594-021-00674-7

مصطلحات موضوعية: 0303 health sciences, Drug discovery, Protein Conformation, Chemistry, G protein, Allosteric regulation, Computational Biology, SUPERFAMILY, Computational biology, Article, Computational biology and bioinformatics, Receptors, G-Protein-Coupled, 3. Good health, Enzyme Activation, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Humans, Databases, Protein, Receptor, Molecular Biology, 030217 neurology & neurosurgery, Signal Transduction, 030304 developmental biology, G protein-coupled receptor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc22a72502fef7a2e167b6eb92bb6545

المؤلفون: Morgan Scott-Dennis, Fikri A. Rafani, Yicheng Yi, Themiya Perera, Clare R. Harwood, Wolfgang Guba, Arne C. Rufer, Uwe Grether, Dmitry B. Veprintsev, David A. Sykes

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, G-protein signaling, Gαi signaling pathway, cannabinoid receptors (CBRs), inverse agonism, BRET—bioluminescence resonance energy transfer, GPCR signalling assay, Gαi signalling assay

Relation: https://figshare.com/articles/dataset/Table1_Development_of_a_membrane-based_Gi-CASE_biosensor_assay_for_profiling_compounds_at_cannabinoid_receptors_DOCX/23930703

الاتاحة: https://doi.org/10.3389/fphar.2023.1158091.s001
https://figshare.com/articles/dataset/Table1_Development_of_a_membrane-based_Gi-CASE_biosensor_assay_for_profiling_compounds_at_cannabinoid_receptors_DOCX/23930703

المؤلفون: Sean A, Cullum, Dmitry B, Veprintsev, Stephen J, Hill

المصدر: British journal of pharmacology.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c8ce626a1bf3adbde52233f029731455
https://pubmed.ncbi.nlm.nih.gov/36495270

المؤلفون: Martina Radli, Dmitry B Veprintsev, Stefan G D Rüdiger

المصدر: PLoS ONE, Vol 12, Iss 6, p e0180047 (2017)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC5484490?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/7c4440e1eb984fe2a62dd6edc3b580f7

الاتاحة: https://doi.org/10.1371/journal.pone.0180047
https://doaj.org/article/7c4440e1eb984fe2a62dd6edc3b580f7

المؤلفون: Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Claudia Korn, David Sykes, Gabriel Forn-Cuni, Patrick Pfaff, Roman C. Sarott, Matthias V. Westphal, Yelena Mostinski, Leonard Mach, Malgorzata Wasinska-Kalwa, Marie Weise, Bradley L. Hoare, Tamara Miljuš, Maira Mexi, Nicolas Roth, Eline J. Koers, Wolfgang Guba, André Alker, Arne C. Rufer, Eric A. Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A. Zirwes, Anja Osterwald, Anto Pavlovic, Svenja Moes, Jennifer Beck, Matthias Nettekoven, Irene Benito-Cuesta, Teresa Grande, Faye Drawnel, Gabriella Widmer, Daniela Holzer, Tom van der Wel, Harpreet Mandhair, Michael Honer, Jürgen Fingerle, Jörg Scheffel, Johannes Broichhagen, Klaus Gawrisch, Julián Romero, Cecilia J. Hillard, Zoltan V. Varga, Mario van der Stelt, Pal Pacher, Jürg Gertsch, Christoph Ullmer, Peter J. McCormick, Sergio Oddi, Herman P. Spaink, Mauro Maccarrone, Dmitry B. Veprintsev, Erick M. Carreira, Uwe Grether, Marc Nazaré

المساهمون: Publica

المصدر: Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Korn, Claudia; Sykes, David; Forn-Cuni, Gabriel; Pfaff, Patrick; Sarott, Roman C; Westphal, Matthias V; Mostinski, Yelena; Mach, Leonard; Wasinska-Kalwa, Malgorzata; Weise, Marie; Hoare, Bradley L; Miljuš, Tamara; Mexi, Maira; Roth, Nicolas; Koers, Eline J; Guba, Wolfgang; Alker, André; ... (2022). Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe. Chemical Science, 13(19), pp. 5539-5545. The Royal Society of Chemistry 10.1039/d1sc06659e <http://dx.doi.org/10.1039/d1sc06659e>
Chemical Science, 13(19), 5539-5545
Chemical Science

مصطلحات موضوعية: 570 Life sciences, biology, 610 Medicine & health, General Chemistry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e61ac61b6e5b29da1ceeb545f2c056
http://hdl.handle.net/11697/192023