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1
المؤلفون: J.L. Oskins, Bryan H. Norman, Mark Chambers, Norman Earle Hughes, Stefan Jon Thibodeaux, Matthew Allen Schiffler, Matthew J. Fisher, Thomas W. Seng, Xiao-Peng Yu, C. Lin, Srinivasan Chandrasekhar, Anita K. Harvey
المصدر: Journal of Pharmacology and Experimental Therapeutics. 356:635-644
مصطلحات موضوعية: Male, 0301 basic medicine, Guinea Pigs, Prostaglandin, Arthritis, Inflammation, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Microsomes, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Animals, Humans, Enzyme Inhibitors, Prostaglandin E2, Pain Measurement, Prostaglandin-E Synthases, Analgesics, Dose-Response Relationship, Drug, biology, Imidazoles, Prostanoid, Phenanthrenes, medicine.disease, Rats, Intramolecular Oxidoreductases, 030104 developmental biology, chemistry, Celecoxib, biology.protein, Molecular Medicine, lipids (amino acids, peptides, and proteins), Cyclooxygenase, Analgesia, medicine.symptom, 030217 neurology & neurosurgery, medicine.drug
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2
المؤلفون: Sanjay M. Jachak, Puneet Khurana
المصدر: RSC Advances. 6:28343-28369
مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, medicine.drug_class, General Chemical Engineering, Prostaglandin, Inflammation, Prostacyclin, General Chemistry, Pharmacology, Anti-inflammatory, 03 medical and health sciences, chemistry.chemical_compound, Thromboxane A2, 030104 developmental biology, chemistry, In vivo, Discovery and development of cyclooxygenase 2 inhibitors, medicine, lipids (amino acids, peptides, and proteins), medicine.symptom, Prostaglandin E2, medicine.drug
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3
المصدر: Medicinal Research Reviews. 34:825-855
مصطلحات موضوعية: Pharmacology, Chemistry, Prostaglandin E2 receptor, Prostaglandin, Prostacyclin, Prostaglandin-E Synthases, Thromboxane A2, chemistry.chemical_compound, Biochemistry, Drug Discovery, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Molecular Medicine, lipids (amino acids, peptides, and proteins), Prostaglandin D2, Prostaglandin E2, medicine.drug
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4
المؤلفون: Terry J. Smith
المصدر: Experimental and Clinical Endocrinology & Diabetes. 107:S160-S163
مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Prostaglandin E2 receptor, Connective tissue, Inflammation, Dinoprostone, Pathogenesis, chemistry.chemical_compound, Endocrinology, Internal medicine, Discovery and development of cyclooxygenase 2 inhibitors, Internal Medicine, medicine, Humans, CD40 Antigens, Receptor, Lymphokines, biology, Membrane Proteins, Prostanoid, General Medicine, Graves Disease, Cell biology, Isoenzymes, medicine.anatomical_structure, chemistry, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Enzyme Induction, biology.protein, Cytokines, Cyclooxygenase, medicine.symptom, Orbit
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5
المؤلفون: Bengt Samuelsson, Jan T. Svensson, Mats Hamberg
المصدر: Nutrition Reviews. 44:208-211
مصطلحات موضوعية: Blood Platelets, Serotonin, Platelet Aggregation, Stereochemistry, Thromboxane, Medicine (miscellaneous), Arachidonic Acids, Mass Spectrometry, Thromboxane receptor, Thromboxane Production, chemistry.chemical_compound, Thromboxane A2, Discovery and development of cyclooxygenase 2 inhibitors, Humans, Platelet, Prostaglandin G2, Pyrans, Multidisciplinary, Nutrition and Dietetics, biology, Peroxides, Thromboxane B2, chemistry, Thromboxanes, Prostaglandins, biology.protein, Arachidonic acid, Thromboxane-A synthase, Hydroxy Acids, Prostaglandin H2, Research Article
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6
المؤلفون: Bengt Samuelsson, Jesper Z. Haeggström, Tove Hammarberg, Henrik Hansson, Mats Hamberg, Anders Wetterholm
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Models, Molecular, Prostaglandin E2 receptor, Mutation, Missense, Prostaglandin, Arginine, Crystallography, X-Ray, Dinoprost, Prostaglandin E synthase, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Microsomes, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Humans, Prostaglandin E2, Molecular Biology, Prostaglandin-E synthase activity, Prostaglandin-E Synthases, Enzyme Catalysis and Regulation, biology, Chemistry, Cell Biology, Protein Structure, Tertiary, Intramolecular Oxidoreductases, Amino Acid Substitution, Structural Homology, Protein, biology.protein, Prostaglandin H2, lipids (amino acids, peptides, and proteins), Oxidoreductases, medicine.drug
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7
المصدر: Journal of Biological Chemistry. 282:34468-34478
مصطلحات موضوعية: Prostaglandin E2 receptor, Golgi Apparatus, Prostaglandin, Biochemistry, Dinoprostone, symbols.namesake, chemistry.chemical_compound, Phospholipase A2, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Humans, RNA, Small Interfering, Prostaglandin E2, Molecular Biology, Cells, Cultured, Annexin A1, Arachidonic Acid, biology, Group IV Phospholipases A2, Endothelial Cells, Cell Biology, Golgi apparatus, Cell biology, Enzyme Activation, Endothelial stem cell, chemistry, Prostaglandin-Endoperoxide Synthases, symbols, biology.protein, Calcium, lipids (amino acids, peptides, and proteins), Lysophospholipids, medicine.drug
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8
المصدر: Cellular Physiology and Biochemistry. 20:607-616
مصطلحات موضوعية: chemistry.chemical_classification, biology, Physiology, Chemistry, Prostaglandin, Pharmacology, chemistry.chemical_compound, Biochemistry, Arachidonate 5-lipoxygenase, Discovery and development of cyclooxygenase 2 inhibitors, medicine, biology.protein, Arachidonic acid, Cyclooxygenase, Prostaglandin E2, CYP2C8, medicine.drug, Polyunsaturated fatty acid
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9
المؤلفون: Mi-Ra Cho, Xiang-Hua Han, Yeo-Pyo Yun, Yong Lim, Yong-Ri Jin, Jung-Jin Lee, Hwan-Soo Yoo, Ki-Wan Oh, Kyung-Sup Lee, Jin-Tae Hong
المصدر: Basic Toxicology. 97:162-167
مصطلحات موضوعية: Blood Platelets, medicine.medical_specialty, In Vitro Techniques, Toxicology, Receptors, Thromboxane A2, Prostaglandin H2, Thromboxane receptor, Inhibitory Concentration 50, chemistry.chemical_compound, Thromboxane A2, Fibrinolytic Agents, Internal medicine, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Animals, 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid, Platelet activation, Pharmacology, Arachidonic Acid, Dose-Response Relationship, Drug, biology, Prostaglandin D2, General Medicine, Thromboxane B2, Endocrinology, chemistry, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid, biology.protein, Arachidonic acid, Collagen, Rabbits, Thromboxane-A Synthase, Thromboxane-A synthase, Platelet Aggregation Inhibitors, Prostaglandin H2, Naphthoquinones
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10
المؤلفون: Chandan Alam, Michael Seed
المصدر: InflammoPharmacology. 12:477-480
مصطلحات موضوعية: Pharmacology, Modern medicine, Aspirin, biology, business.industry, Immunology, Prostaglandin, Inflammation, Disease, chemistry.chemical_compound, chemistry, Discovery and development of cyclooxygenase 2 inhibitors, medicine, biology.protein, Experimental pathology, Pharmacology (medical), Cyclooxygenase, medicine.symptom, business, medicine.drug
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11Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis
المؤلفون: Tomoyuki Inoue, Shiro Nakaike, Nobutaka Takahashi, Masanori Sugimoto, Iwao Arai, Yuki Hashimoto, Norikazu Takano, Nobuko Futaki
المصدر: European Journal of Pharmacology. 505:229-235
مصطلحات موضوعية: Male, medicine.medical_specialty, Time Factors, Prostaglandin E2 receptor, Indomethacin, Receptors, Prostaglandin, Prostaglandin, Mice, Inbred Strains, 6-Ketoprostaglandin F1 alpha, Dinoprost, Dinoprostone, Dermatitis, Atopic, Mice, chemistry.chemical_compound, Internal medicine, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Animals, Alprostadil, Prostaglandin E2, Prostaglandin E1, Skin, Pharmacology, Mice, Inbred ICR, Arachidonic Acid, Behavior, Animal, Dose-Response Relationship, Drug, Prostaglandin D2, Pruritus, Anti-Inflammatory Agents, Non-Steroidal, Prostanoid, Epoprostenol, Endocrinology, Prostaglandin F2alpha, chemistry, Prostaglandins, lipids (amino acids, peptides, and proteins), Histamine, medicine.drug
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12
المؤلفون: Vera V. Shaposhnikova, Grichenko Oe, Kudriavtsev Aa, Korystov IuN
المصدر: Biology Bulletin. 31:221-225
مصطلحات موضوعية: biology, Prostaglandin, Pharmacology, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Baicalein, chemistry.chemical_compound, Lipoxygenase, Leukemia, chemistry, Biochemistry, Apoptosis, Discovery and development of cyclooxygenase 2 inhibitors, biology.protein, medicine, Cyclooxygenase, Prostaglandin E2, General Agricultural and Biological Sciences, medicine.drug
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13
المؤلفون: Makoto Murakami, Ichiro Kudo
المصدر: Progress in Lipid Research. 43:3-35
مصطلحات موضوعية: Prostaglandin E2 receptor, medicine.medical_treatment, Prostaglandin E synthase, Models, Biological, Biochemistry, Isozyme, Dinoprostone, Phospholipases A, Cell Physiological Phenomena, Cyclooxygenase pathway, Mice, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Animals, Humans, Cyclooxygenase Inhibitors, Prostaglandin-E Synthases, Inflammation, Arachidonic Acid, biology, Cell Biology, Molecular biology, Cell biology, Intramolecular Oxidoreductases, Isoenzymes, Gene Expression Regulation, Prostaglandin-Endoperoxide Synthases, biology.protein, Female, lipids (amino acids, peptides, and proteins), Cyclooxygenase, Cell activation, Prostaglandin E
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14
المؤلفون: Natasha Imtiaz Hansraj, Sagheer Ahmad, Abdul Mueed Zafar, Sarah Khalid Khan, Asthma Mushir Ahmad Khan, Muhammad A. Rauf, Sheikh Arshad Saeed, Saira Abdul Aziz Samani, Ameer Zaigham Rasheed, Kashfa Farhat
المصدر: Journal of Biological Sciences. 3:1188-1202
مصطلحات موضوعية: Prostaglandin biosynthesis, Biochemistry, biology, Chemistry, Human plasma, Haptoglobin, Discovery and development of cyclooxygenase 2 inhibitors, biology.protein, Albumin, Molecular Medicine, Cell Biology
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15
المؤلفون: Christian Villeneuve, Julie Parent, Michel Fortier
المصدر: Reproduction. :539-547
مصطلحات موضوعية: Embryology, medicine.medical_specialty, Stromal cell, Prostaglandin E2 receptor, Blotting, Western, Prostaglandin, Biology, Dinoprost, Oxytocin, Endometrium, Dinoprostone, chemistry.chemical_compound, Endocrinology, Internal medicine, Discovery and development of cyclooxygenase 2 inhibitors, Luteolysis, medicine, Animals, Cells, Cultured, Nitrobenzenes, Sulfonamides, Arachidonic Acid, Anti-Inflammatory Agents, Non-Steroidal, Obstetrics and Gynecology, Epithelial Cells, Cell Biology, Salicylates, Stimulation, Chemical, Isoenzymes, medicine.anatomical_structure, Flurbiprofen, Reproductive Medicine, chemistry, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Cyclooxygenase 1, biology.protein, Cattle, Female, lipids (amino acids, peptides, and proteins), Arachidonic acid, Cyclooxygenase
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16
المؤلفون: Vicente Arroyo, Joan Clària
المصدر: Prostaglandins & Other Lipid Mediators. 72:19-33
مصطلحات موضوعية: Physiology, Arachidonic Acids, Pharmacology, Kidney, Biochemistry, chemistry.chemical_compound, Liver disease, Discovery and development of cyclooxygenase 2 inhibitors, medicine, Animals, Humans, biology, business.industry, Liver Diseases, Kidney metabolism, Cell Biology, medicine.disease, medicine.anatomical_structure, chemistry, Prostaglandin-Endoperoxide Synthases, Prostaglandins, biology.protein, Kidney Diseases, Arachidonic acid, Cyclooxygenase, business
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17
المؤلفون: Wilfred A. van der Donk, Ah-Lim Tsai, L. Mattias Blomberg, Per E. M. Siegbahn, Margareta R. A. Blomberg
المصدر: The Journal of Physical Chemistry B. 107:3297-3308
مصطلحات موضوعية: Quantum chemical, biology, ATP synthase, Chemistry, Prostaglandin E2 receptor, Active site, Pharmacology, Surfaces, Coatings and Films, chemistry.chemical_compound, Discovery and development of cyclooxygenase 2 inhibitors, Materials Chemistry, biology.protein, lipids (amino acids, peptides, and proteins), Cyclooxygenase, Physical and Theoretical Chemistry, Prostaglandin endoperoxide, Prostaglandin G2
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18
المؤلفون: Elizabeth D. Thuresson, Michael G. Malkowski, R. Michael Garavito, Karen M. Lakkides, William L. Smith, Caroline Jill Rieke, Renée Micielli
المصدر: International Congress Series. 1233:283-289
مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Prostaglandin, Fatty acid, General Medicine, chemistry.chemical_compound, chemistry, Biochemistry, Fatty acid binding, Discovery and development of cyclooxygenase 2 inhibitors, Free fatty acid receptor, Arachidonic acid, CYP2C8, Polyunsaturated fatty acid
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19
المؤلفون: Claus Schneider, Alan R. Brash
المصدر: Journal of Biological Chemistry. 275:4743-4746
مصطلحات موضوعية: biology, Stereochemistry, Prostaglandin, Active site, Cell Biology, Hydrogen atom abstraction, Biochemistry, Serine, chemistry.chemical_compound, Stereospecificity, chemistry, Discovery and development of cyclooxygenase 2 inhibitors, biology.protein, lipids (amino acids, peptides, and proteins), Arachidonic acid, Cyclooxygenase, Molecular Biology
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20
المؤلفون: Karin Valmsen, Nigulas Samel, Reet Koljak, Alan R. Brash, Külliki Varvas, Ivar Järving
المصدر: Journal of Biological Chemistry. 274:9923-9929
مصطلحات موضوعية: chemistry.chemical_classification, biology, Stereochemistry, Jasmonic acid, Cell Biology, Metabolism, Biochemistry, chemistry.chemical_compound, Lipoxygenase, Enzyme, Tolfenamic acid, chemistry, Biosynthesis, Discovery and development of cyclooxygenase 2 inhibitors, medicine, biology.protein, Cyclooxygenase, Molecular Biology, medicine.drug