المؤلفون: Ryman-Rasmussen, Jessica P., Griffith, Adam, Oloff, Scott, Vaidehi, Nagarajan, Brown, Justin T., Goddard, William A., III, Mailman, Richard B.

المصدر: Neuropharmacology, 52(2), 562-575, (2007-02)

مصطلحات موضوعية: D1 dopamine receptors, Receptor internalization, Receptor recycling, Adenylate cyclase, Functional selectivity, A-77636, Dinapsoline, Dopamine

Relation: https://doi.org/10.1016/j.neuropharm.2006.08.028; https://www.ncbi.nlm.nih.gov/pmc/PMC1855220; eprintid:93284

الاتاحة: https://www.ncbi.nlm.nih.gov/pmc/PMC1855220
https://doi.org/10.1016/j.neuropharm.2006.08.028

المؤلفون: Russell A Grubbs, Mechelle M Lewis, Connie Owens-Vance, Elaine A Gay, Amy K Jassen, Richard B Mailman, David E Nichols

المصدر: Bioorganic & Medicinal Chemistry. 12:1403-1412

مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Dopamine, Clinical Biochemistry, Pharmaceutical Science, Dinapsoline, CHO Cells, Naphthols, Ligands, Biochemistry, Chemical synthesis, Dihydrexidine, chemistry.chemical_compound, Cricetinae, Drug Discovery, medicine, Animals, Humans, Protein Isoforms, Isoquinoline, Molecular Biology, Receptors, Dopamine D2, Receptors, Dopamine D1, Organic Chemistry, Glioma, Isoquinolines, Corpus Striatum, Rats, chemistry, Dinoxyline, Dopamine Agonists, Molecular Medicine, Bioisostere, Pharmacophore, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c949056b886650dd501efbd75bf09fd7
https://doi.org/10.1016/j.bmc.2004.01.008

المؤلفون: Scott D. Gleason, Witkin Jm

المصدر: Behavioural Pharmacology. 15:85-89

مصطلحات موضوعية: Male, Agonist, Tetrahydronaphthalenes, Pyridines, medicine.drug_class, Dinapsoline, Naphthols, Pharmacology, Partial agonist, Dihydrexidine, Discrimination Learning, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine receptor D1, medicine, Animals, Drug Interactions, Prodrugs, Receptor, Appetitive Behavior, Motivation, SCH-23390, Chemistry, Receptors, Dopamine D1, Stereoisomerism, Isoquinolines, Receptor antagonist, Phenanthridines, Rats, Psychiatry and Mental health, Dopamine Agonists, Conditioning, Operant, 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142b6da7c578a25d8b197c7671e43c37
https://doi.org/10.1097/00008877-200402000-00010

المؤلفون: Amy K Jassen, Amjad M. Qandil, David E. Nichols, Richard B. Mailman, Sarah K. Leonard, Mechelle M. Lewis

المصدر: Bioorganic & Medicinal Chemistry. 11:1451-1464

مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Substituent, Pharmaceutical Science, Dinapsoline, Stereoisomerism, Naphthols, In Vitro Techniques, Biochemistry, Dopamine agonist, Chemical synthesis, Dihydrexidine, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Cyclic AMP, Tumor Cells, Cultured, medicine, Animals, Cloning, Molecular, Molecular Biology, Brain Neoplasms, Receptors, Dopamine D2, Chemistry, Receptors, Dopamine D1, Cell Membrane, Organic Chemistry, Glioma, Isoquinolines, Recombinant Proteins, Rats, Neostriatum, Cyclization, Dopamine Agonists, Molecular Medicine, Indicators and Reagents, Pharmacophore, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6899984cf2c9df5aaa5ee8830b91426
https://doi.org/10.1016/s0968-0896(02)00561-8

المؤلفون: Amit G. Gulwadi, Subramaniam Krishnananthan, Matthew T. Taber, Henry Wong, Thaddeus F. Molski, Carolyn D. Korpinen, Kai Xie, Cen Xu, Qi Gao, Elaine Ryan, Graham Johnson, Swanee Jacutin-Porte, Juliang Zhu, Todd A. Verdoorn, Kevin D. Burris, Sing-Yuen Sit

المصدر: Journal of Medicinal Chemistry. 45:3660-3668

مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Molecular Conformation, Convergent synthesis, Dinapsoline, Naphthols, In Vitro Techniques, Crystallography, X-Ray, Chemical synthesis, Dopamine agonist, Cell Line, Rats, Sprague-Dawley, Radioligand Assay, chemistry.chemical_compound, Drug Discovery, Cyclic AMP, medicine, Animals, Isoquinoline, Receptors, Dopamine D2, Receptors, Dopamine D1, Stereoisomerism, Isoquinolines, Corpus Striatum, Rats, chemistry, Dopamine Agonists, Molecular Medicine, Pharmacophore, Enantiomer, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f8d563bbfcdbebff234ec75f7665f6
https://doi.org/10.1021/jm0101545

المؤلفون: Tim Sattelkau, David E. Nichols, Amjad M. Qandil

المصدر: Synthesis. 2001:0262-0266

مصطلحات موضوعية: Acylation, Agonist, medicine.drug_class, Chemistry, Dopamine, Organic Chemistry, medicine, Dinapsoline, Selective reduction, Electrophilic aromatic substitution, Combinatorial chemistry, Catalysis, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::624bd9668d702752d91459c84b2719e3
https://doi.org/10.1055/s-2001-10809

المؤلفون: Val J. Watts, David E. Nichols, Scott E. Snyder, Richard B. Mailman, Debasis Ghosh

المصدر: Journal of Medicinal Chemistry. 39:549-555

مصطلحات موضوعية: Agonist, Phenanthridine, medicine.drug_class, Stereochemistry, Dinapsoline, Biological activity, Methylene bridge, Dihydrexidine, chemistry.chemical_compound, chemistry, Drug Discovery, medicine, Molecular Medicine, Isoquinoline, Pharmacophore, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3f74e99e73495d18c3beaac9f5bab98c
https://doi.org/10.1021/jm950707+

المؤلفون: Supriyo Bhattacharya, Richard B. Mailman, Jonathan D. Urban, Nagarajan Vaidehi, J. Corey Fowler

مصطلحات موضوعية: Agonist, Intrinsic activity, medicine.drug_class, Protein Conformation, Dinapsoline, CHO Cells, Biology, Ligands, Dihydrexidine, chemistry.chemical_compound, Radioligand Assay, Dopamine receptor D1, Quinpirole, Cricetulus, Cricetinae, medicine, Functional selectivity, Serine, Animals, Pharmacology, Receptors, Dopamine D2, Articles, Biochemistry, chemistry, Guanosine 5'-O-(3-Thiotriphosphate), Dinoxyline, Mutation, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdde985b4b49550a2d878c7478e986ce
https://europepmc.org/articles/PMC3362898/

المؤلفون: David E. Nichols, Richard B. Mailman, Val J. Watts, Scott E. Snyder, Debasis Ghosh

المصدر: ChemInform. 27

مصطلحات موضوعية: Agonist, Phenanthridine, Molecular model, medicine.drug_class, Stereochemistry, Dinapsoline, General Medicine, Methylene bridge, Dihydrexidine, chemistry.chemical_compound, chemistry, medicine, Isoquinoline, Pharmacophore, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::07a9f92a16c89e4d5be2848343607bb5
https://doi.org/10.1002/chin.199619167

المؤلفون: Amjad M. Qandil, Debasis Ghosh, David E. Nichols

المصدر: ChemInform. 30

مصطلحات موضوعية: Formal synthesis, chemistry.chemical_compound, chemistry, Stereochemistry, medicine, Dinapsoline, General Medicine, Isoquinoline, Dopamine agonist, Combinatorial chemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::975a8de60760769d54dfbd8dbcb87ce9
https://doi.org/10.1002/chin.199929147

المؤلفون: Sing-Yuen Sit, et al. et al.

المصدر: ChemInform. 33

مصطلحات موضوعية: Chemistry, medicine, Dinapsoline, General Medicine, Pharmacology, Dopamine agonist, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a737c13f76fac8becf3ef604d8852fd
https://doi.org/10.1002/chin.200252141

المؤلفون: Ao Zhang, Jing Zhang, Bing Xiong, Xuechu Zhen

المصدر: ChemInform. 40

مصطلحات موضوعية: Agonist, Doxanthrine, Intrinsic activity, medicine.drug_class, Dinapsoline, General Medicine, Pharmacology, Dihydrexidine, chemistry.chemical_compound, Dopamine receptor D1, chemistry, Dinoxyline, medicine, Receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e46d5d1686bc1aeb00d77e912d93cd7a
https://doi.org/10.1002/chin.200920269

المؤلفون: Justin C. Brown, Yan-Min Wang, Andrew Kant, Richard B. Mailman

المصدر: Functional Selectivity of G Protein-Coupled Receptor Ligands ISBN: 9781603273343

مصطلحات موضوعية: Intrinsic activity, Chemistry, Dopamine receptor, Dopamine receptor D2, Functional selectivity, medicine, Dinapsoline, Drug action, Neuroscience, Endogenous agonist, Dihydrexidine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3c65f625cd68bb7d7241cf08258123eb
https://doi.org/10.1007/978-1-60327-335-0_10

المؤلفون: Debasis Ghosh, Amjad M. Qandil, David E. Nichols

المصدر: The Journal of Organic Chemistry. 64:1407-1409

مصطلحات موضوعية: chemistry.chemical_compound, Formal synthesis, chemistry, Stereochemistry, Organic Chemistry, medicine, Dinapsoline, Isoquinoline, Dopamine agonist, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bfbe1aba6df7fa92988d3a82172b1e4b
https://doi.org/10.1021/jo982067z

المؤلفون: Jessica P. Ryman-Rasmussen, Richard B. Mailman, David E. Nichols

المصدر: Molecular pharmacology. 68(4)

مصطلحات موضوعية: Agonist, Intrinsic activity, medicine.drug_class, media_common.quotation_subject, Dinapsoline, Ligands, Dihydrexidine, Cell Line, chemistry.chemical_compound, Dopamine receptor D1, Functional selectivity, medicine, Humans, heterocyclic compounds, Internalization, media_common, Pharmacology, Chemistry, Receptors, Dopamine D1, Enzyme Activation, Biochemistry, Dinoxyline, Biophysics, Molecular Medicine, medicine.drug, Adenylyl Cyclases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2f4ecc3bc501829aac26a25688f0d9
https://pubmed.ncbi.nlm.nih.gov/15985612

المؤلفون: Elaine A. Gay, Jonathan D. Urban, David E. Nichols, Gerry S. Oxford, Richard B. Mailman

المصدر: Molecular pharmacology. 66(1)

مصطلحات موضوعية: Potassium Channels, Dinapsoline, Gene Expression, CHO Cells, Ligands, Dihydrexidine, Dopamine receptor D2, Cricetinae, medicine, Functional selectivity, Cyclic AMP, Animals, Humans, G protein-coupled inwardly-rectifying potassium channel, Phosphorylation, Potassium Channels, Inwardly Rectifying, Pharmacology, Chemistry, Receptors, Dopamine D2, Chinese hamster ovary cell, Colforsin, Cell biology, Phenanthridines, Biochemistry, G Protein-Coupled Inwardly-Rectifying Potassium Channels, Dopamine Agonists, Molecular Medicine, Female, Signal transduction, Mitogen-Activated Protein Kinases, Cyclase activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec95d1db8407e1046d9fe08d9bcfd8d8
https://pubmed.ncbi.nlm.nih.gov/15213300

المؤلفون: Carolyn D. Korpinen, James Seanz, David E. Nichols, Amit G. Gulwadi, Kevin D. Burris, Thaddeus F. Molski, Cen Xu, Richard B. Mailman, Matthew T. Taber, Kai Xie, Kenneth M. Boy, Sing Yuen Sit, Todd A. Verdoorn, Swanee Jacutin-Porte, Elaine Ryan, Graham Johnson

المصدر: Bioorganicmedicinal chemistry. 12(4)

مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Dinapsoline, Naphthols, Biochemistry, Chemical synthesis, Dihydrexidine, Structure-Activity Relationship, Drug Discovery, medicine, Structure–activity relationship, Animals, Molecular Biology, Cells, Cultured, Aza Compounds, Molecular Structure, Chemistry, Organic Chemistry, Biological activity, Dopamine receptor binding, Fluorine, Isoquinolines, Rats, Molecular Medicine, Enantiomer, medicine.drug, Adenylyl Cyclases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82dea99474ba0f78cf8407fd4fec167
https://pubmed.ncbi.nlm.nih.gov/14759732

المؤلفون: Cassandra Prioleau, Mechelle M. Lewis, Richard B. Mailman, Jason D. Kilts, David E. Nichols, Martin K.-H. Doll, Cindy P. Lawler

المصدر: Journal of medicinal chemistry. 42(5)

مصطلحات موضوعية: Male, Quinelorane, Stereochemistry, Dinapsoline, Naphthols, In Vitro Techniques, Binding, Competitive, Dihydrexidine, Rats, Sprague-Dawley, Radioligand Assay, Structure-Activity Relationship, Quinpirole, Dopamine, Dopamine receptor D2, Drug Discovery, medicine, Animals, Chemistry, Receptors, Dopamine D2, organic chemicals, Receptors, Dopamine D1, Dopaminergic, Isoquinolines, Rats, Neostriatum, Dopamine receptor, Dopamine Agonists, Quinolines, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34408219e2db7d05200cae50908e9e54
https://pubmed.ncbi.nlm.nih.gov/10072690

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.wag.caltech.edu/publications/sup/pdf/699.pdf.

مصطلحات موضوعية: D1 dopamine receptors, Receptor internalization, Receptor recycling, Adenylate cyclase, Functional selectivity, A-77636, Dinapsoline, Dopamine

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.584.1402; http://www.wag.caltech.edu/publications/sup/pdf/699.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.584.1402
http://www.wag.caltech.edu/publications/sup/pdf/699.pdf

المؤلفون: Sergei Laiter, David M. Mottola, Alexander Tropsha, David E. Nichols, Steven D. Wyrick, Val J. Watts, Richard B. Mailman

المصدر: Journal of medicinal chemistry. 39(1)

مصطلحات موضوعية: Agonist, Intrinsic activity, Stereochemistry, medicine.drug_class, Dopamine, Molecular Conformation, Dinapsoline, Ligands, Dihydrexidine, Structure-Activity Relationship, Dopamine receptor D1, Drug Discovery, medicine, Animals, Computer Simulation, Molecular Structure, Chemistry, Receptors, Dopamine D1, Brain, Phenanthridines, Rats, Dopamine receptor, Dopamine Agonists, Molecular Medicine, Pharmacophore, Cyclase activity, Software, medicine.drug, Adenylyl Cyclases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779ee27665843e5910487ffd00764eef
https://pubmed.ncbi.nlm.nih.gov/8568818