المؤلفون: Evan L. Barrios, Leandro Balzano-Nogueira, Valerie E. Polcz, Christine Rodhouse, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Shawn D. Larson, Ashish Sharma, Gilburt Upchurch, Shannon M. Wallet, Todd M. Brusko, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Rhonda Bacher, Guoshuai Cai, Michael P. Kladde, Clayton E. Mathews, Lyle L. Moldawer, Maigan A. Brusko, Philip A. Efron

المصدر: Frontiers in Immunology, Vol 15 (2024)

مصطلحات موضوعية: lymphocytes, single-cell RNA sequencing, chronic critical illness, sepsis, human, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1478471/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/e0557e75cb90464e859377a738355ef4

المؤلفون: Evan L. Barrios, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Micah Willis, Valerie E. Polcz, Gwendolyn S. Gillies, Jennifer A. Munley, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie-Pierre L. Gauthier, Shawn D. Larson, Laurence Morel, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Michael P. Kladde, Clayton E. Mathews, Maigan A. Brusko, Todd M. Brusko, Lyle L. Moldawer, Rhonda Bacher, Philip A. Efron

المصدر: Frontiers in Immunology, Vol 15 (2024)

مصطلحات موضوعية: myeloid-derived suppressor cells, sepsis, transcriptomics, single-cell RNA sequencing, chronic critical illness, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355405/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/c3d9f1e91fd841aa9fdb8d5f4c7a4bf1

المؤلفون: McKenzie K. Hollen, Julie A. Stortz, Dijoia Darden, Marvin L. Dirain, Dina C. Nacionales, Russell B. Hawkins, Michael C. Cox, Maria-Cecilia Lopez, Jaimar C. Rincon, Ricardo Ungaro, Zhongkai Wang, Quran Wu, Babette Brumback, Marie-Pierre L. Gauthier, Michael Kladde, Christiaan Leeuwenburgh, Mark Segal, Azra Bihorac, Scott Brakenridge, Frederick A. Moore, Henry V. Baker, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron

المصدر: Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)

مصطلحات موضوعية: Myeloid-derived suppressor cells, Sepsis, Surgery, Human, Epigenetics, miRNA, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13054-019-2628-x; https://doaj.org/toc/1364-8535

URL الوصول: https://doaj.org/article/6b9df6c997a446a79a45c0e33340dd88

المؤلفون: Dijoia B. Darden, Xiaoru Dong, Maigan A. Brusko, Lauren Kelly, Brittany Fenner, Jaimar C. Rincon, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie Gauthier, Michael Kladde, Todd M. Brusko, Azra Bihorac, Frederick A. Moore, Tyler Loftus, Rhonda Bacher, Lyle L. Moldawer, Alicia M. Mohr, Philip A. Efron

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: lymphocytes, immune cells, sepsis, transcriptome, scRNA-seq, chronic critical illness, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.696536/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/51a30572482c44a2b71957447ab39708

المؤلفون: Quan Vo, Zachary D. Simon, Gwoncheol Park, Dina C Nacionales, Carmelina Gorski, Evan L Barrios, Gemma Casadesus, Philip A Efron, Lyle L Moldawer, Ravinder Nagpal, Paramita Chakrabarty, Marcelo Febo

المصدر: NeuroImage, Vol 305, Iss , Pp 120995- (2025)

مصطلحات موضوعية: Sepsis, Spleen, Gut microbiome, Astrocyte, Microglia, fMRI, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

Relation: http://www.sciencedirect.com/science/article/pii/S1053811924004920; https://doaj.org/toc/1095-9572; https://doaj.org/article/249334fb16a044b8961617c4cb6bc5c1

الاتاحة: https://doi.org/10.1016/j.neuroimage.2024.120995
https://doaj.org/article/249334fb16a044b8961617c4cb6bc5c1

المؤلفون: Evan L. Barrios, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Micah Willis, Valerie E. Polcz, Gwendolyn S. Gillies, Jennifer A. Munley, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie-Pierre L. Gauthier, Shawn D. Larson, Laurence Morel, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Michael P. Kladde, Clayton E. Mathews, Maigan A. Brusko, Todd M. Brusko, Lyle L. Moldawer, Rhonda Bacher, Philip A. Efron

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, myeloid-derived suppressor cells, sepsis, transcriptomics, single-cell RNA sequencing, chronic critical illness

Relation: https://figshare.com/articles/figure/Image_5_The_post-septic_peripheral_myeloid_compartment_reveals_unexpected_diversity_in_myeloid-derived_suppressor_cells_tif/25678971

الاتاحة: https://doi.org/10.3389/fimmu.2024.1355405.s007
https://figshare.com/articles/figure/Image_5_The_post-septic_peripheral_myeloid_compartment_reveals_unexpected_diversity_in_myeloid-derived_suppressor_cells_tif/25678971

المؤلفون: Evan L. Barrios, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Micah Willis, Valerie E. Polcz, Gwendolyn S. Gillies, Jennifer A. Munley, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie-Pierre L. Gauthier, Shawn D. Larson, Laurence Morel, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Michael P. Kladde, Clayton E. Mathews, Maigan A. Brusko, Todd M. Brusko, Lyle L. Moldawer, Rhonda Bacher, Philip A. Efron

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, myeloid-derived suppressor cells, sepsis, transcriptomics, single-cell RNA sequencing, chronic critical illness

Relation: https://figshare.com/articles/dataset/DataSheet_1_The_post-septic_peripheral_myeloid_compartment_reveals_unexpected_diversity_in_myeloid-derived_suppressor_cells_xlsx/25678950

الاتاحة: https://doi.org/10.3389/fimmu.2024.1355405.s001
https://figshare.com/articles/dataset/DataSheet_1_The_post-septic_peripheral_myeloid_compartment_reveals_unexpected_diversity_in_myeloid-derived_suppressor_cells_xlsx/25678950

المؤلفون: Philip Alexander, Efron, Dijoia B, Darden, Eric C, Li, Jennifer, Munley, Lauren, Kelly, Brittany, Fenner, Dina C, Nacionales, Ricardo F, Ungaro, Marvin L, Dirain, Jaimar, Rincon, Robert T, Mankowski, Christiaan, Leeuwenburgh, Fredrick A, Moore, Scott C, Brakenridge, Thomas C, Foster, Orlando, Laitano, Gemma, Casadesus, Lyle L, Moldawer, Alicia M, Mohr, Ryan M, Thomas

المصدر: Journal of Trauma and Acute Care Surgery. 93:137-146

مصطلحات موضوعية: Male, Mice, Inbred C57BL, Disease Models, Animal, Mice, Sex Characteristics, Microbiota, RNA, Ribosomal, 16S, Sepsis, Animals, Female, Surgery, Critical Care and Intensive Care Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367651eb1bed522361ba9e4d0912c963
https://doi.org/10.1097/ta.0000000000003599

المؤلفون: Steven L Raymond, Russell B Hawkins, Julie A Stortz, Tyler J Murphy, Ricardo Ungaro, Marvin L Dirain, Dina C Nacionales, McKenzie K Hollen, Jaimar C Rincon, Shawn D Larson, Scott C Brakenridge, Frederick A Moore, Daniel Irimia, Phil A Efron, Lyle L Moldawer

المصدر: PLoS ONE, Vol 13, Iss 10, p e0205327 (2018)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC6177179?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/1c5f2e78debb4f66a5976e9c00530182

الاتاحة: https://doi.org/10.1371/journal.pone.0205327
https://doaj.org/article/1c5f2e78debb4f66a5976e9c00530182

المؤلفون: Robert T. Mankowski, Dina C. Nacionales, Lyle L. Moldawer, Thomas L. Clanton, Raad Z. Gharaibeh, Scott C. Brakenridge, Dijoia B Darden, Alicia M. Mohr, Philip A. Efron, F. A. Moore, Christiaan Leeuwenburgh, Russell B. Hawkins, Marvin L. Dirain, Camille G Apple, Michael C. Cox, Orlando Laitano, Ricardo Ungaro, Ryan M. Thomas

المصدر: Shock

مصطلحات موضوعية: Male, medicine.medical_treatment, 030204 cardiovascular system & hematology, Gut flora, Critical Care and Intensive Care Medicine, Article, Sepsis, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Chronic stress, Microbiome, Young adult, Feces, biology, Catabolism, business.industry, Age Factors, 030208 emergency & critical care medicine, Immunosuppression, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, Mice, Inbred C57BL, Immunology, Emergency Medicine, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec267d74d44f472655b6cfda3b2d5f5
https://doi.org/10.1097/shk.0000000000001648

المؤلفون: Ricardo Ungaro, Lyle L. Moldawer, Jaimar Rincon, Philip A. Efron, Dina C. Nacionales, Russell B. Hawkins, Shawn D. Larson, McKenzie K. Hollen

المصدر: Shock

مصطلحات موضوعية: Male, Myeloid, Inflammasomes, medicine.medical_treatment, 030204 cardiovascular system & hematology, Critical Care and Intensive Care Medicine, Article, Sepsis, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Adjuvants, Immunologic, Immunity, NLR Family, Pyrin Domain-Containing 3 Protein, Animals, Medicine, Myeloid Cells, Neonatal sepsis, business.industry, 030208 emergency & critical care medicine, Inflammasome, Dendritic cell, medicine.disease, Mice, Inbred C57BL, Survival Rate, Disease Models, Animal, medicine.anatomical_structure, Animals, Newborn, Immunology, Emergency Medicine, Alum Compounds, Female, Neonatal Sepsis, business, Adjuvant, Granulocytes, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8671ed70628c01d01312b9ad31d4123
https://doi.org/10.1097/shk.0000000000001623

المؤلفون: Maria-Cecilia Lopez, Scott C. Brakenridge, Lyle L. Moldawer, Ashrita Budharaju, Brittany P Fenner, Tyler J. Loftus, Philip A. Efron, Dijoia B Darden, Juan C. Mira, Julie A. Stortz, Dina C. Nacionales, Alicia M. Mohr, Frederick A. Moore, Henry V. Baker, Lauren S Kelly

المصدر: J Trauma Acute Care Surg

مصطلحات موضوعية: Male, Aging, Shock, Hemorrhagic, Critical Care and Intensive Care Medicine, Article, Andrology, Mice, Bone Marrow, Gene expression, microRNA, medicine, Animals, Humans, Young adult, Progenitor cell, Innate immune system, medicine.diagnostic_test, business.industry, Multiple Trauma, Gene Expression Profiling, Age Factors, Cell Differentiation, Hematopoietic Stem Cells, Immunity, Innate, Hematopoiesis, Mice, Inbred C57BL, Haematopoiesis, Disease Models, Animal, medicine.anatomical_structure, Bronchoalveolar lavage, Gene Expression Regulation, Surgery, Bone marrow, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c110c688ee4fd436c9fe9f0c04cdcff9
https://pubmed.ncbi.nlm.nih.gov/34252063

المؤلفون: Marie-Pierre L. Gauthier, Alicia M. Mohr, Russell B. Hawkins, Michael P. Kladde, Maigan A. Brusko, Marvin L. Dirain, Parker Knight, Azra Bihorac, Jaimar Rincon, Ricardo Ungaro, Frederick A. Moore, Lyle L. Moldawer, Todd M. Brusko, Scott C. Brakenridge, Dina C. Nacionales, Michael C. Cox, Philip A. Efron, Rhonda Bacher, Dijoia B Darden

المصدر: Shock

مصطلحات موضوعية: medicine.medical_treatment, Cell, Pilot Projects, 030204 cardiovascular system & hematology, Biology, Critical Care and Intensive Care Medicine, Peripheral blood mononuclear cell, Epitope, Article, Sepsis, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, RNA-Seq, Myeloid-Derived Suppressor Cells, Cancer, 030208 emergency & critical care medicine, Immunosuppression, medicine.disease, medicine.anatomical_structure, Immunology, Emergency Medicine, Myeloid-derived Suppressor Cell, Single-Cell Analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60457279469bfdd46b09674c3fabc071
https://europepmc.org/articles/PMC8019679/

المؤلفون: Lori F Gentile, Dina C Nacionales, M Cecilia Lopez, Erin Vanzant, Angela Cuenca, Benjamin E Szpila, Alex G Cuenca, Anna Joseph, Frederick A Moore, Christiaan Leeuwenburgh, Henry V Baker, Lyle L Moldawer, Philip A Efron

المصدر: PLoS ONE, Vol 9, Iss 5, p e94404 (2014)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC4006924?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/3c84415d1f584ee89b76d5879e500e32

الاتاحة: https://doi.org/10.1371/journal.pone.0094404
https://doaj.org/article/3c84415d1f584ee89b76d5879e500e32

المؤلفون: Alicia M. Mohr, Tezcan Ozrazgat-Baslanti, Babette Brumback, Scott C. Brakenridge, Tyler J. Loftus, Julie A. Stortz, Frederick A. Moore, Tyler J. Murphy, Ricardo Ungaro, Philip A. Efron, Azra Bihorac, Juan C. Mira, Lyle L. Moldawer, Zhongkai Wang, Dina C. Nacionales, Steven L. Raymond, Marvin L. Dirain, Gabriela L. Ghita

المصدر: Shock. 49:249-258

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Critical Illness, Lymphocyte, medicine.medical_treatment, Secondary infection, Critical Care and Intensive Care Medicine, Article, B7-H1 Antigen, Sepsis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Immune Tolerance, medicine, Humans, Lymphocyte Count, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, Aged, business.industry, Incidence (epidemiology), 030208 emergency & critical care medicine, Immunosuppression, HLA-DR Antigens, Middle Aged, medicine.disease, Clinical trial, medicine.anatomical_structure, Immunology, Emergency Medicine, Biomarker (medicine), Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf06670c0017cb1397da5fb0d6065b56
https://doi.org/10.1097/shk.0000000000000981

المؤلفون: Dijoia B. Darden (9019154), Xiaoru Dong (6724497), Maigan A. Brusko (8710959), Lauren Kelly (3565658), Brittany Fenner (11276232), Jaimar C. Rincon (5832707), Marvin L. Dirain (1339185), Ricardo Ungaro (5821175), Dina C. Nacionales (11276235), Marie Gauthier (7504517), Michael Kladde (7863071), Todd M. Brusko (8710965), Azra Bihorac (222400), Frederick A. Moore (9087636), Tyler Loftus (11276238), Rhonda Bacher (4686679), Lyle L. Moldawer (358625), Alicia M. Mohr (9019172), Philip A. Efron (9019175)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, lymphocytes, immune cells, sepsis, transcriptome, scRNA-seq, chronic critical illness

Relation: https://figshare.com/articles/dataset/Table_2_A_Novel_Single_Cell_RNA-seq_Analysis_of_Non-Myeloid_Circulating_Cells_in_Late_Sepsis_xlsx/15171519

الاتاحة: https://doi.org/10.3389/fimmu.2021.696536.s006

المؤلفون: Dijoia B. Darden (9019154), Xiaoru Dong (6724497), Maigan A. Brusko (8710959), Lauren Kelly (3565658), Brittany Fenner (11276232), Jaimar C. Rincon (5832707), Marvin L. Dirain (1339185), Ricardo Ungaro (5821175), Dina C. Nacionales (11276235), Marie Gauthier (7504517), Michael Kladde (7863071), Todd M. Brusko (8710965), Azra Bihorac (222400), Frederick A. Moore (9087636), Tyler Loftus (11276238), Rhonda Bacher (4686679), Lyle L. Moldawer (358625), Alicia M. Mohr (9019172), Philip A. Efron (9019175)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, lymphocytes, immune cells, sepsis, transcriptome, scRNA-seq, chronic critical illness

Relation: https://figshare.com/articles/dataset/DataSheet_2_A_Novel_Single_Cell_RNA-seq_Analysis_of_Non-Myeloid_Circulating_Cells_in_Late_Sepsis_pdf/15171507

الاتاحة: https://doi.org/10.3389/fimmu.2021.696536.s002

المؤلفون: Dossier Autoimmunity, Yoshiki Kuroda A, Dina C. Nacionales A, Jun Akaogi A, Westley H. Reeves A, Minoru Satoh A

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://qbit.cc/blog/wp-content/uploads/2009/09/oil-adjuvant-induced-autoimmunity-Kuroda-et-al.pdf?origin%3Dpublication_detail.

مصطلحات موضوعية: Adjuvant, Autoimmunity, Pristane

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.660.7753; http://qbit.cc/blog/wp-content/uploads/2009/09/oil-adjuvant-induced-autoimmunity-Kuroda-et-al.pdf?origin%3Dpublication_detail

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.660.7753
http://qbit.cc/blog/wp-content/uploads/2009/09/oil-adjuvant-induced-autoimmunity-Kuroda-et-al.pdf?origin%3Dpublication_detail

المؤلفون: Ricardo Ungaro, Lyle L. Moldawer, Shawn D. Larson, Brittany Mathias, Steven L. Raymond, Jaimar Rincon, James L. Wynn, Angela L. Cuenca, Philip A. Efron, Dina C. Nacionales

المصدر: Clinical and Experimental Immunology. 191:268-278

مصطلحات موضوعية: 0301 basic medicine, Neutrophils, T-Lymphocytes, medicine.medical_treatment, Immunology, chemical and pharmacologic phenomena, Extracellular Traps, Sepsis, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Adjuvants, Immunologic, Phagocytosis, Animals, Humans, Immunology and Allergy, Medicine, Myeloid Cells, Cell Self Renewal, Alum adjuvant, Mice, Knockout, B-Lymphocytes, Innate immune system, Neonatal sepsis, biology, business.industry, Alum, Caspase 1, Original Articles, Neutrophil extracellular traps, medicine.disease, Caspases, Initiator, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Animals, Newborn, chemistry, Caspases, Neutrophil elastase, Bacterial Vaccines, Macrophages, Peritoneal, biology.protein, Alum Compounds, business, Adjuvant, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d222ad5772fdaa2754d61925c296a6e8
https://doi.org/10.1111/cei.13072

المؤلفون: Stepan Shumyak, Xin Qi, Ravil Khaybullin, Pui Y. Lee, Yuan Zhang, Amina Chatha, Dina C. Nacionales, Lyle L. Moldawer, Shuhong Han, Westley H. Reeves, Haoyang Zhuang, Li-Jun Yang, Chao Xie, Anan B. Afaneh, Li Lu

المصدر: Arthritis & Rheumatology. 69:1280-1293

مصطلحات موضوعية: Lung Diseases, 0301 basic medicine, Receptor expression, Immunology, Hemorrhage, Inflammation, Article, Pathogenesis, Mice, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, medicine, Animals, Humans, Lupus Erythematosus, Systemic, Immunology and Allergy, Macrophage, Lung, Lupus erythematosus, Systemic lupus erythematosus, Terpenes, business.industry, Macrophages, Diffuse alveolar hemorrhage, Macrophage Activation, medicine.disease, Interleukin-10, Mice, Inbred C57BL, Pulmonary Alveoli, Antibody opsonization, Disease Models, Animal, 030104 developmental biology, Female, medicine.symptom, business, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a96276ca3af2cc01fd5c8752b9f4af8
https://doi.org/10.1002/art.40077