المؤلفون: Tan, Zhulin, Ju, Xuan, Wu, Hao, Dong, Weitong, Leung, Joyce C., Hou, Xiaowen, Lee, Heewon, Granger, Alice, Paolillo, Joshua M., DiMeo, Susan V., Chen, Chengsheng, Wu, Linglin, Lorenz, Jon C., Sarvestani, Max, Buono, Frederic, Frutos, Rogelio, Tampone, Thomas G., Huang, Xiaojun, Zhang, Gulin, Wang, Yuwen, Spinelli, Earl, Lei, Zhen, Song, Jinhua J.

المصدر: Organic Process Research & Development ; volume 28, issue 1, page 78-91 ; ISSN 1083-6160 1520-586X

الاتاحة: http://dx.doi.org/10.1021/acs.oprd.3c00363
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00363

المؤلفون: Leung, Joyce C., Xu, Yibo, Radomkit, Suttipol, Lee, Jaehee, Kim, Wan Shin, Reeves, Jonathan T., Dong, Weitong, Jang, Hwanjong, Hou, Xiaowen, Lorenz, Jon C., Shao, Xiaole, Byrne, Denis, Johnson, Joe, Brundage, Anthony, Valentin, Clement, Beyer, Phouvieng, DiMeo, Susan V., Qu, Bo, Li, Ruoshi, Sarvestani, Max, Song, Jinhua J.

المصدر: Organic Process Research & Development ; volume 28, issue 1, page 67-77 ; ISSN 1083-6160 1520-586X

الاتاحة: http://dx.doi.org/10.1021/acs.oprd.3c00362
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00362

المؤلفون: Robert C. Bruckner, Andrew M. Stern, Anne Higley, Graciani Nilsa R, Sandya Mandlekar, Maria Rafalski, Melody Diamond, Ross L. Stein, Eddy W. Yue, Xiang Jiang, Pearl S. Huang, Randine Dowling, Dimeo Susan, Lisa C. Grimminger, Mingzhu Zhang, Zhihong Lai, Amy L. Musselman, Swamy Yeleswaram, Davette L. Behrens, Robert A. Copeland, Andrew P. Combs, Oliff Allen I, Wei Han, Shu-Yun Zhang, Rebecca Taub, Bruce Car, George L. Trainor, Charles F. Albright, Steve P. Seitz, Daniel Hu

المصدر: Molecular Cancer Therapeutics. 4:751-760

مصطلحات موضوعية: Cancer Research, Reticulocytes, Drug-Related Side Effects and Adverse Reactions, Matrix Metalloproteinases, Membrane-Associated, Fibrosarcoma, Transplantation, Heterologous, Pharmacology, Mice, Therapeutic index, Tumor Cells, Cultured, medicine, Animals, Humans, Prodrugs, Doxorubicin, Neprilysin, Chemistry, Metalloendopeptidases, Prodrug, medicine.disease, Peptide Fragments, In vitro, Transplantation, Matrix Metalloproteinase 9, Oncology, Matrix Metalloproteinase 2, HT1080, Drug Screening Assays, Antitumor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45501a8fa2fc432573f20a1fa75bdc1c
https://doi.org/10.1158/1535-7163.mct-05-0006

المؤلفون: Angela Smallwood, Jodi K. Muckelbauer, Sarah Cox, C. Anne Higley, Steven P. Seitz, Eddy W. Yue, George L. Trainor, Dimeo Susan, Haiying Chen, Robert H. Grafstrom, Pamela A. Benfield, Jay A. Markwalder, Catherine R. Burton, Chong Hwan Chang

المصدر: Bioorganic & Medicinal Chemistry Letters. 14:343-346

مصطلحات موضوعية: Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Biochemistry, Heterocyclic Compounds, Cyclin-dependent kinase, Cell Line, Tumor, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Protein kinase A, Fibroblast, Molecular Biology, chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, Fibroblasts, Blood proteins, Cyclin-Dependent Kinases, In vitro, medicine.anatomical_structure, Enzyme, Enzyme inhibitor, Cell culture, biology.protein, Pyrazoles, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eca9874d090f1248663ed651625ea7e
https://doi.org/10.1016/j.bmcl.2003.11.008

المؤلفون: Angela Smallwood, Dimeo Susan, Carrie Benware, Eddy W. Yue, David J. Carini, C. Anne Higley, Lisa M. Sisk, David A. Nugiel, Chong-Hwan Chang, Catherine R. Burton, Diane M. Sharp, Pamela A. Benfield, Jodi K. Muckelbauer, Sarah Cox, Steven P. Seitz, Haiying Chen, John F. Boylan, Robert H. Grafstrom, George L. Trainor

المصدر: Journal of Medicinal Chemistry. 45:5233-5248

مصطلحات موضوعية: chemistry.chemical_classification, biology, Molecular model, Kinase, medicine.drug_class, Stereochemistry, Carboxamide, Chemical synthesis, chemistry, Enzyme inhibitor, Cyclin-dependent kinase, Drug Discovery, biology.protein, medicine, Molecular Medicine, Transferase, Alkyl

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::275f3847362bdca5f8cb1694b8f56d26
https://doi.org/10.1021/jm0201722