نتائج البحث - "Didier Saur"

1

Pharmacokinetics of Single-dose Ertugliflozin in Patients With Hepatic Impairment

المؤلفون: Anne Hickman, Susan Zhou, Didier Saur, Steven G. Terra, David L. Cutler, Vaishali Sahasrabudhe, Kyle Matschke, Sangeeta Raje, Haihong Shi

المصدر: Clinical Therapeutics. 40:1701-1710

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c0451a6b71bbbcb1fd31bb3a1f4123
https://doi.org/10.1016/j.clinthera.2018.06.015

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2

Effect of Rifampin on the Pharmacokinetics of Ertugliflozin in Healthy Subjects

المؤلفون: Vikas Kumar Dawra, Didier Saur, David L. Cutler, Anne Hickman, Steven G. Terra, Yali Liang, Vaishali Sahasrabudhe, Kyle Matschke, Haihong Shi

المصدر: Clinical Therapeutics. 40:1538-1547

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01bdef95febdcaf94e60cb47c4ca455
https://doi.org/10.1016/j.clinthera.2018.07.014

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3

Novel Application of the Two-Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin

المؤلفون: Klaas Schildknegt, Eric Fluhler, Lloyd Stevens, Eric Woolf, Alfin D. N. Vaz, Haihong Shi, Steven G. Terra, Dimitris Papadopoulos, Vaishali Sahasrabudhe, Didier Saur, Daniel Gaunt, Kyle Matschke, Robert J. Fountaine, Susan Zhou, David L. Cutler, Ernesto Callegari, Sangeeta Raje, Christine Alvey

المصدر: Clinical and Translational Science. 11:405-411

مصطلحات موضوعية: Chromatography, Chemistry, General Neuroscience, Sodium, Area under the curve, chemistry.chemical_element, Fraction (chemistry), General Medicine, Absorption (skin), Urine, Tandem mass spectrometry, Mass spectrometry, 030226 pharmacology & pharmacy, General Biochemistry, Genetics and Molecular Biology, Bioavailability, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, General Pharmacology, Toxicology and Pharmaceutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::43daa919a2dc9a808114b7cd6503d3f6
https://doi.org/10.1111/cts.12549

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4

The Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Ertugliflozin in Subjects With Type 2 Diabetes Mellitus

المؤلفون: D. L. Cutler, Z. Zhou, Didier Saur, Harry Shi, Melissa O'Gorman, Anne Hickman, Steven G. Terra, Vaishali Sahasrabudhe

المصدر: The Journal of Clinical Pharmacology. 57:1432-1443

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d06ace71c76d8b8f62a25cce6f2e73a9
https://doi.org/10.1002/jcph.955

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5

Phase III, efficacy and safety study of ertugliflozin monotherapy in people with type 2 diabetes mellitus inadequately controlled with diet and exercise alone

المؤلفون: Gregory T. Golm, Kristen Focht, Steven G. Terra, Brett Lauring, Didier Saur, Jeremy Johnson, Samuel Dagogo-Jack, Melanie J. Davies, Giuseppe Derosa, Juan P. Frias, Amanda Darekar

المصدر: Diabetes, Obesity and Metabolism. 19:721-728

مصطلحات موضوعية: Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, Placebo, Reproductive Tract Infections, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Double-Blind Method, Sodium-Glucose Transporter 2, Membrane Transport Modulators, Internal medicine, Diet, Diabetic, Internal Medicine, medicine, Clinical endpoint, Humans, Hypoglycemic Agents, Adverse effect, Exercise, Immunity, Mucosal, Sodium-Glucose Transporter 2 Inhibitors, Glycated Hemoglobin, Dose-Response Relationship, Drug, business.industry, Incidence, Incidence (epidemiology), Type 2 Diabetes Mellitus, Overweight, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Combined Modality Therapy, Hypoglycemia, Surgery, Blood pressure, Postprandial, Diabetes Mellitus, Type 2, Mycoses, Hyperglycemia, Female, Anti-Obesity Agents, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8640dc844a311f5e78eaf9f243c887
https://doi.org/10.1111/dom.12888

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6

Effect of ertugliflozin on glucose control, body weight, blood pressure and bone density in type 2 diabetes mellitus inadequately controlled on metformin monotherapy (VERTIS MET)

المؤلفون: Steven G. Terra, Raluca Pascu, Bernard Charbonnel, Didier Saur, Susan Huyck, Amanda Darekar, Dénes Páll, Juan P. Frias, Harry Shi, Brett Lauring, Julio Rosenstock

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, endocrine system diseases, Bone density, Endocrinology, Diabetes and Metabolism, Urinary system, Blood Pressure, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Placebo, Klinikai orvostudományok, Gastroenterology, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Double-Blind Method, Bone Density, Internal medicine, Weight Loss, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Adverse effect, Sodium-Glucose Transporter 2 Inhibitors, Aged, Glycated Hemoglobin, business.industry, Incidence (epidemiology), Type 2 Diabetes Mellitus, Orvostudományok, Middle Aged, Bridged Bicyclo Compounds, Heterocyclic, Metformin, Treatment Outcome, Blood pressure, Diabetes Mellitus, Type 2, Female, business, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea840a427b6241ac27c016a7369edccf

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7

A Phase 1, Randomized, Placebo- and Active-Controlled Crossover Study to Determine the Effect of Single-Dose Ertugliflozin on QTc Interval in Healthy Volunteers

المؤلفون: Anne Hickman, Didier Saur, Isabelle Huyghe, Haihong Shi, Vaishali Sahasrabudhe, Kyle Matschke, David L. Cutler, Steven G. Terra

المصدر: Clinical pharmacology in drug development. 7(5)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87babea7e4b03c974309a5b780d9fc6
https://pubmed.ncbi.nlm.nih.gov/29346837

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8

Academic Journal

Efficacy and safety of namilumab, a human monoclonal antibody against granulocyte-macrophage colony-stimulating factor (GM-CSF) ligand in patients with rheumatoid arthritis (RA) with either an inadequate response to background methotrexate therapy or an inadequate response or intolerance to an anti-TNF (tumour necrosis factor) biologic therapy: a randomized, controlled trial

المؤلفون: Peter C. Taylor, Didier Saurigny, Jiri Vencovsky, Tsutomu Takeuchi, Tadashi Nakamura, Galina Matsievskaia, Barbara Hunt, Thomas Wagner, Bernard Souberbielle, for the NEXUS Study Group

المصدر: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-13 (2019)

مصطلحات موضوعية: Rheumatoid arthritis, Namilumab, GM-CSF, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-019-1879-x; https://doaj.org/toc/1478-6362

URL الوصول: https://doaj.org/article/2a809e0128b548da80279d3a1a9e0751

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9

Academic Journal

Experimental Optimization of Passive Cooling of a Heat Source Array Flush-Mounted on a Vertical Plate

المؤلفون: Antoine Baudoin, Didier Saury, Bo Zhu, Cecilia Boström

المصدر: Energies, Vol 9, Iss 11, p 912 (2016)

مصطلحات موضوعية: discrete heat sources, source array, natural convection, optimization, Technology

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1996-1073/9/11/912; https://doaj.org/toc/1996-1073

URL الوصول: https://doaj.org/article/0047538d77b74de291422014c53d2add

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