المؤلفون: Donat Kögel, Heiko Düssmann, Haiyan Wang, Hella Wobser, Jochen H. M. Prehn, Maria M. Byrne, Claus Reimertz, Claes B. Wollheim

المصدر: Journal of Biological Chemistry, Vol. 277, No 8 (2002) pp. 6413-21

مصطلحات موضوعية: Bcl-X Protein, MODY 3, Apoptosis, Diabetes Mellitus, Type 2/genetics/physiopathology, Mitochondrion, Biochemistry, chemistry.chemical_compound, Suppression, Genetic, 0302 clinical medicine, Cell Death/drug effects, Tumor Cells, Cultured, Hepatocyte Nuclear Factor 1-alpha, ddc:616, 0303 health sciences, Cell Death, Nuclear Proteins, Apoptosis/physiology, Cell cycle, Glucose/pharmacology, Recombinant Proteins, Mitochondria, DNA-Binding Proteins, Proto-Oncogene Proteins c-bcl-2, Doxycycline, Hepatocyte Nuclear Factor 1, embryonic structures, Transcriptional Activation, medicine.medical_specialty, Ceramide, Programmed cell death, Transcription Factors/genetics, bcl-X Protein, Biology, Transfection, digestive system, Cell Line, Doxycycline/pharmacology, 03 medical and health sciences, Internal medicine, medicine, Mitochondria/physiology, Animals, Humans, Recombinant Proteins/biosynthesis, Proto-Oncogene Proteins c-bcl-2/genetics/metabolism, Molecular Biology, Hepatocyte Nuclear Factor 1-beta, 030304 developmental biology, Cell growth, Cell Biology, medicine.disease, Molecular biology, Rats, Pancreatic Neoplasms, Glucose, Endocrinology, Diabetes Mellitus, Type 2, chemistry, Cell culture, Mutation, Insulinoma, Transcriptional Activation/drug effects, DNA-Binding Proteins/genetics, 030217 neurology & neurosurgery, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67ceb8605f135e06900a0bec37ba2be
https://doi.org/10.1074/jbc.m108390200

المؤلفون: Claes B. Wollheim, Rolf Graf, Siobhan Bacon, Angela M. Farrelly, Seán M. Kilbride, Jochen H. M. Prehn, Chantal M. Boulanger, S. R. Rizvi, Mathurin Baquié, Manus W. Ward, Caoimhín G. Concannon, Heiko Düssmann, Maria M. Byrne, Caroline Bonner

المصدر: Diabetes
Diabetes, Vol. 59, No 11 (2010) pp. 2799-808

مصطلحات موضوعية: Insulinoma/genetics, Programmed cell death, endocrine system, Insulin-Secreting Cells/cytology/drug effects/physiology, Endocrinology, Diabetes and Metabolism, Caspase 3, Apoptosis, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Diabetes Mellitus, Type 2/genetics/physiopathology, 03 medical and health sciences, Mice, 0302 clinical medicine, Cell Death/drug effects, Insulin-Secreting Cells, Gene expression, Internal Medicine, medicine, Animals, Humans, Hepatocyte Nuclear Factor 1-alpha/genetics/pharmacology, Hepatocyte Nuclear Factor 1-alpha, ddc:612, Promoter Regions, Genetic, Caspase, 030304 developmental biology, 0303 health sciences, biology, Cell Death, Cell growth, Reverse Transcriptase Polymerase Chain Reaction, Molecular biology, Rats, Mice, Inbred C57BL, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Caspases/genetics/pharmacology, 030220 oncology & carcinogenesis, Hepatocyte, Caspases, biology.protein, Insulinoma, Beta cell, Caspase 3/metabolism, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4831e2fb7802971147569552297d62
https://pubmed.ncbi.nlm.nih.gov/20682686

المؤلفون: Xiaojian Zhao, Marco Pontoglio, Moshe Yaniv, Richard G. Kibbey, Gary W. Cline, Clare L. Kirkpatrick, Rebecca L. Pongratz, Claes B. Wollheim, Gerald I. Shulman

المصدر: Journal of Biological Chemistry, Vol. 284, No 25 (2009) pp. 16808-21

مصطلحات موضوعية: Male, medicine.medical_treatment, Glutamine, Mitochondria/drug effects/metabolism, Hepatocyte Nuclear Factor 1-alpha/deficiency/genetics/metabolism, Mitochondrion, Diabetes Mellitus, Type 2/genetics/physiopathology, Biochemistry, Oxidative Phosphorylation, Islets of Langerhans/drug effects/metabolism/secretion, Mice, Adenosine Triphosphate, Insulin Secretion, Pyruvic Acid, Insulin, Glycolysis, Hepatocyte Nuclear Factor 1-alpha, Glucose Transporter Type 2, Mice, Knockout, ATP synthase, Glucose/pharmacology, Mitochondria, Metabolism and Bioenergetics, Female, ATP–ADP translocase, Pyruvic Acid/pharmacology, medicine.medical_specialty, RNA, Messenger/genetics/metabolism, Oxidative phosphorylation, Biology, Cell Line, Islets of Langerhans, Leucine, Internal medicine, medicine, Animals, Humans, RNA, Messenger, ddc:612, Molecular Biology, DNA Primers, Insulin/secretion, DNA Primers/genetics, Adenosine Triphosphate/biosynthesis, Base Sequence, Glucose Transporter Type 2/genetics, Cell Biology, Metabolism, Glutamine/pharmacology, Leucine/pharmacology, Rats, Citric acid cycle, Endocrinology, Glucose, Diabetes Mellitus, Type 2, Mutation, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ad706f51e195f50c1c607b3f06a4a2
https://pubmed.ncbi.nlm.nih.gov/19376774