المؤلفون: Kan, W.L., Dhagat, U., Hercus, T.R., Kaufmann, K.B., Nero, T.L., Zeng, A.G.X., Toubia, J., Barry, E.F., Broughton, S.E., Gomez, G.A., Dottore, M., Cheung Tung Shing, K.S., Thomas, D., Benard, B., Simpson, K.J., Schoof, E., Goodall, G.J., Begley, C.G., Ekert, P.G., Tvorogov, D.

المصدر: http://dx.doi.org/10.1158/2159-8290.cd-22-1396.

مصطلحات موضوعية: heterodimeric receptors, stoichiometry, biased signaling, stem cells, cytokines, pleiotropy, stemness, leukemia, receptor oligomerization, Humans, Receptors, Cytokine, Signal Transduction, Cell Proliferation, Phosphorylation, Neoplastic Stem Cells, Myeloid, Acute

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1071897; http://purl.org/au-research/grants/nhmrc/1182564; http://purl.org/au-research/grants/nhmrc/2021560; http://purl.org/au-research/grants/nhmrc/1148221; http://purl.org/au-research/grants/nhmrc/1123401; http://purl.org/au-research/grants/nhmrc/1098567; http://purl.org/au-research/grants/nhmrc/1117183; http://purl.org/au-research/grants/nhmrc/1194263; Cancer Discovery, 2023; 13(8):1922-1947; https://hdl.handle.net/2440/139756; Goodall, G.J. [0000-0003-1294-0692]; Lopez, A. [0000-0001-7430-0135]

الاتاحة: https://hdl.handle.net/2440/139756
https://doi.org/10.1158/2159-8290.CD-22-1396

المؤلفون: Broughton, S., Hercus, T., Nero, T., Kan, W., Barry, E., Dottore, M., Cheung Tung Shing, K., Morton, C., Dhagat, U., Hardy, M., Wilson, N., Downton, M., Schieber, C., Hughes, T., Lopez, A., Parker, M.

المصدر: http://dx.doi.org/10.1038/s41467-017-02633-7.

مصطلحات موضوعية: Cercopithecus aethiops

وصف الملف: application/pdf

Relation: Nature Communications, 2018; 9(1):386-1-386-15; http://hdl.handle.net/2440/116606; Hughes, T. [0000-0002-0910-3730] [0000-0002-7990-4509]; Lopez, A. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/116606
https://doi.org/10.1038/s41467-017-02633-7

المؤلفون: Cheung Tung Shing, K.S., Broughton, S.E., Nero, T.L., Gillinder, K., Ilsley, M.D., Ramshaw, H., Lopez, A.F., Griffin, M.D.W., Parker, M.W., Perkins, A.C., Dhagat, U.

المصدر: http://dx.doi.org/10.1038/s41598-018-29865-x.

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1036849; http://purl.org/au-research/grants/nhmrc/1071897; http://purl.org/au-research/grants/nhmrc/1122401; Scientific Reports, 2018; 8(1):12457-1-12457-16; http://hdl.handle.net/2440/119882; Ramshaw, H. [0000-0001-9909-282X]; Lopez, A.F. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/119882
https://doi.org/10.1038/s41598-018-29865-x

المؤلفون: Shing, KSCT, Broughton, SE, Nero, TL, Gillinder, K, Ilsley, MD, Ramshaw, H, Lopez, AF, Griffin, MDW, Parker, MW, Perkins, AC, Dhagat, U

Relation: NHMRC/1117183; pii: 10.1038/s41598-018-29865-x; Shing, K. S. C. T., Broughton, S. E., Nero, T. L., Gillinder, K., Ilsley, M. D., Ramshaw, H., Lopez, A. F., Griffin, M. D. W., Parker, M. W., Perkins, A. C. & Dhagat, U. (2018). EPO does not promote interaction between the erythropoietin and beta-common receptors. SCIENTIFIC REPORTS, 8 (1), https://doi.org/10.1038/s41598-018-29865-x.; http://hdl.handle.net/11343/216235

الاتاحة: http://hdl.handle.net/11343/216235

المؤلفون: Panousis, C., Dhagat, U., Edwards, K.M., Rayzman, V., Hardy, M.P., Braley, H., Gauvreau, G.M., Hercus, T.R., Smith, S., Sehmi, R., McMillan, L., Dottore, M., McClure, B.J., Fabri, L.J., Vairo, G., Lopez, A.F., Parker, M.W., Nash, A.D., Wilson, N.J., Wilson, M.J.

المصدر: http://dx.doi.org/10.1080/19420862.2015.1119352.

مصطلحات موضوعية: Affinity maturation, GM-CSF, IL-3, IL-5, asthma, cytokine, eosinophil, myeloid, phage display, therapeutic antibody, β common receptor

وصف الملف: application/pdf

Relation: mAbs, 2016; 8(3):436-453; http://hdl.handle.net/2440/101845; McClure, B.J. [0000-0002-5201-4127]; Lopez, A.F. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/101845
https://doi.org/10.1080/19420862.2015.1119352

المؤلفون: Broughton, S., Hercus, T., Hardy, M., McClure, B., Nero, T., Dottore, M., Huynh, H., Braley, H., Barry, E., Kan, W., Dhagat, U., Scotney, P., Hartman, D., Busfield, S., Owczarek, C., Nash, A., Wilson, N., Parker, M., Lopez, A.

المصدر: http://dx.doi.org/10.1016/j.celrep.2014.06.038.

مصطلحات موضوعية: COS Cells, Animals, Cercopithecus aethiops, Humans, Antineoplastic Agents, Binding Sites, Antibody, Amino Acid Sequence, Protein Binding, Molecular Sequence Data, Interleukin-3 Receptor alpha Subunit, HEK293 Cells, Antibodies, Monoclonal, Humanized

وصف الملف: application/pdf

Relation: NHMRC; Cell Reports, 2014; 8(2):410-419; http://hdl.handle.net/2440/101852; McClure, B. [0000-0002-5201-4127]; Lopez, A. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/101852
https://doi.org/10.1016/j.celrep.2014.06.038

المؤلفون: Shing, KSCT, Broughton, SE, Nero, TL, Gillinder, K, Ilsley, MD, Ramshaw, H, Lopez, AF, Griffin, MDW, Parker, MW, Perkins, AC, Dhagat, U

مصطلحات الفهرس: Journal Article

URL: http://hdl.handle.net/11343/230866
NHMRC/1117183

المؤلفون: Dhagat, U., Hercus, T.R., Broughton, S.E., Nero, T.L., Cheung Tung Shing, K.S., Barry, E.F., Thomson, C.A., Bryson, S., Pai, E.F., McClure, B.J., Schrader, J.W., Lopez, A.F., Parker, M.W.

المصدر: http://dx.doi.org/10.1080/19420862.2018.1494107.

مصطلحات موضوعية: Auto-antibodies, Beta common cytokines, GM-CSF, GM-CSF mutations, X-ray crystallography, anti-GM-CSF therapeutics, pulmonary alveolar proteinosis

Relation: http://purl.org/au-research/grants/nhmrc/1117183; http://purl.org/au-research/grants/nhmrc/1071897; mAbs, 2018; 10(7):1018-1029; http://hdl.handle.net/2440/117651; McClure, B.J. [0000-0002-5201-4127]; Lopez, A.F. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/117651
https://doi.org/10.1080/19420862.2018.1494107

المؤلفون: Hercus, T., Kan, W., Broughton, S., Tvorogov, D., Ramshaw, H., Sandow, J., Nero, T., Dhagat, U., Thompson, E., Tung Shing, K., McKenzie, D., Wilson, N., Owczarek, C., Vairo, G., Nash, A., Tergaonkar, V., Hughes, T., Ekert, P., Samuel, M., Bonder, C.

المصدر: http://dx.doi.org/10.1101/cshperspect.a028514.

مصطلحات موضوعية: Humans, Sepsis, Inflammation, Cytokines, Signal Transduction, Gene Expression Regulation

Relation: Cold Spring Harbor perspectives in biology, 2018; 10(6):a028514-a028514; http://hdl.handle.net/2440/113919; Ramshaw, H. [0000-0001-9909-282X]; Hughes, T. [0000-0002-0910-3730] [0000-0002-7990-4509]; Samuel, M. [0000-0001-7880-6379]; Bonder, C. [0000-0001-9875-967X]; Lopez, A. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/113919
https://doi.org/10.1101/cshperspect.a028514

المؤلفون: Dhagat, U., Nero, T.L., Kan, W.L., Hercus, T.R., Broughton, S.E., de Weerd, N.A., Jenkins, B.J., Mansell, A., Guthridge, M.A., Hertzog, P.J., Lopez, A.F., Parker, M.W.

المصدر: Encyclopedia of Cell Biology ; page 22-36 ; ISBN 9780123947963

الاتاحة: http://dx.doi.org/10.1016/b978-0-12-394447-4.30002-5
https://api.elsevier.com/content/article/PII:B9780123944474300025?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:B9780123944474300025?httpAccept=text/plain

المؤلفون: Dhagat, U, Hercus, TR, Broughton, SE, Nero, TL, Shing, KSCT, Barry, EF, Thomson, CA, Bryson, S, Pai, EF, McClure, BJ, Schrader, JW, Lopez, AF, Parker, MW

مصطلحات الفهرس: Journal Article

URL: http://hdl.handle.net/11343/290492
NHMRC/1117183

المؤلفون: Broughton, S.E., Hercus, T.R., Nero, T.L., King-Scott, J., Lopez, A.F., Parker, M.W., Dottore, M., McClure, B.J., Dhagat, U., Taing, H., Gorman, M.A.

المصدر: http://www.sciencedirect.com/science/article/pii/S0969212616301241.

مصطلحات موضوعية: Humans, Escherichia coli, Granulocyte-Macrophage Colony-Stimulating Factor, Receptors, Protein Subunits, Recombinant Proteins, Crystallography, X-Ray, Cloning, Molecular, Signal Transduction, Gene Expression, Binding Sites, Amino Acid Motifs, Protein Binding, Mutation, Protein Interaction Domains and Motifs, Protein Multimerization, Molecular Dynamics Simulation, Molecular Docking Simulation, Protein Conformation, alpha-Helical, beta-Strand

Relation: NHMRC; Structure, 2016; 24(8):1271-1281; http://hdl.handle.net/2440/102459; Lopez, A.F. [0000-0001-7430-0135]; McClure, B.J. [0000-0002-5201-4127]

الاتاحة: http://hdl.handle.net/2440/102459
https://doi.org/10.1016/j.str.2016.05.017

المؤلفون: Broughton, S.E., Nero, T.L., Dhagat, U., Kan, W.L., Hercus, T.R., Tvorogov, D., Lopez, A.F., Parker, M.W.

المصدر: http://dx.doi.org/10.1016/j.cyto.2015.02.005.

مصطلحات موضوعية: Granulocyte-macrophage colony, stimulating factor, Interleukin-3, Interleukin-5, Beta common receptor, inflammation

Relation: Cytokine, 2015; 74(2):247-258; http://hdl.handle.net/2440/101846; Lopez, A.F. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/101846
https://doi.org/10.1016/j.cyto.2015.02.005

المؤلفون: Broughton, S., Hercus, T., Nero, T., Dhagat, U., Owczarek, C., Hardy, M., Fabri, L., Scotney, P., Nash, A., Wilson, N., Lopez, A., Parker, M.

المصدر: http://dx.doi.org/10.1107/s2053230x14002593.

مصطلحات موضوعية: Crystallization

Relation: NHMRC; Acta Crystallographica Section F: Structural Biology Communications, 2014; 70(3):358-361; http://hdl.handle.net/2440/101854; Lopez, A. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/101854
https://doi.org/10.1107/S2053230X14002593

المؤلفون: Broughton, S., Dhagat, U., Hercus, T., Nero, T., Grimbaldeston, M., Bonder, C., Lopez, A., Parker, M.

المصدر: http://dx.doi.org/10.1111/j.1600-065x.2012.01164.x.

مصطلحات موضوعية: crystal structures, cytokine, granulocyte–macrophage colony-stimulating factor, interleukin-3, interleukin-5, receptor signaling

Relation: Immunological Reviews, 2012; 250(1):277-302; http://hdl.handle.net/2440/76600; Bonder, C. [0000-0001-9875-967X]; Lopez, A. [0000-0001-7430-0135]

الاتاحة: http://hdl.handle.net/2440/76600
https://doi.org/10.1111/j.1600-065X.2012.01164.x

المؤلفون: Lopez, A., Hercus, T., McClure, B., Broughton, S., Dhagat, U., Nero, T., Parker, M.

المصدر: Cytokine ; volume 59, issue 3, page 502 ; ISSN 1043-4666

الاتاحة: http://dx.doi.org/10.1016/j.cyto.2012.06.040
https://api.elsevier.com/content/article/PII:S1043466612002852?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1043466612002852?httpAccept=text/plain

المؤلفون: Ahir, V.B., Koringa, P.G.¹, Bhatt, V.D., Ramani, U.V., Tripathi, A.K., Singh, K.M., Dhagat, U.M., Patel, J.S., Patel, M.M., Katudia, K.H., Sajnani, M.R., Jakhesara, S.J., Joshi, C.G.

المصدر: Indian Journal of Poultry Science 45(2):111-114. 2010