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1Academic Journal
المؤلفون: Le Manach, C., Dam, J., Woodland, J.G., Kaur, G., Khonde, L.P., Brunschwig, C., Njoroge, M., Wicht, K.J., Horatscheck, A., Paquet, T., Boyle, G.A., Gibhard, L., Taylor, D., Lawrence, N., Yeo, T., Mok, S., Eastman, R.T., Dorjsuren, D., Talley, D.C., Guo, H., Simeonov, A., Reader, J., van der Watt, M., Erlank, E., Venter, N., Zawada, J.W., Aswat, A., Nardini, L., Coetzer, T.L., Lauterbach, S.B., Bezuidenhout, B.C., Theron, A., Mancama, D., Koekemoer, L.L., Birkholtz, L., Wittlin, S., Delves, M., Ottilie, S., Winzeler, E.A., von Geldern, T.W., Smith, D., Fidock, D.A., Street, L.J., Basarab, G.S., Duffy, J., Chibale, K.
المساهمون: Kelly Chibale: South African Medical Research Council, Drug Discovery and Development Research Unit
مصطلحات موضوعية: Animals, Germ cells, Molecular structure, Structure-activity relationship, SDG-03 Good health and well-being
Relation: Le Manach C, Dam J, Woodland JG, Kaur G, Khonde LP, Brunschwig C, Njoroge M, Wicht KJ, Horatscheck A, Paquet T, Boyle GA, Gibhard L, Taylor D, Lawrence N, Yeo T, Mok S, Eastman RT, Dorjsuren D, Talley DC, Guo H, Simeonov A, Reader J, van der Watt M, Erlank E, Venter N, Zawada JW, Aswat A, Nardini L, Coetzer TL, Lauterbach SB, Bezuidenhout BC, Theron A, Mancama D, Koekemoer LL, Birkholtz LM, Wittlin S, Delves M, Ottilie S, Winzeler EA, von Geldern TW, Smith D, Fidock DA, Street LJ, Basarab GS, Duffy J, Chibale K. Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite Plasmodium falciparum and Optimization Efforts. J Med Chem. 2021 Feb 25;64(4):2291-2309. doi:10.1021/acs.jmedchem.1c00034. Epub 2021 Feb 12.; Journal of Medicinal Chemistry; https://pubmed.ncbi.nlm.nih.gov/33573376/; https://hdl.handle.net/11288/595614
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2Academic Journal
المؤلفون: Witmer, K, Dahalan, F, Delves, M, Yahiya, S, Watson, O, Straschil, U, Chiwcharoen, D, Sorboon, B, Pukrittayakamee, S, Pearson, R, Howick, V, Lawniczak, M, White, N, Dondorp, A, Okell, L, Chotivanich, K, Ruecker, A, Baum, J
المساهمون: Wellcome Trust, Medicines for Malaria Venture, Medical Research Council (MRC), The Royal Society
المصدر: 17 ; 1
مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Microbiology, Pharmacology & Pharmacy, Anopheles stephensi, Kelch13, Plasmodium falciparum, artemisinin combination therapies (ACTs), gametocytes, multidrug-resistant malaria, transmission blocking, PLASMODIUM-FALCIPARUM MALARIA, MEFLOQUINE RESISTANCE, SOUTHEAST-ASIA, PFMDR1 GENE, OPEN-LABEL, DIHYDROARTEMISININ, HALOFANTRINE, COMBINATION, ARTESUNATE, 0605 Microbiology, 1108 Medical Microbiology, 1115 Pharmacology and Pharmaceutical Sciences
Relation: Antimicrobial Agents and Chemotherapy; http://hdl.handle.net/10044/1/84903; 100993/Z/13/Z; MMV08/2800; 109312/Z/15/Z; MR/N012275/1; DH140134; MR/R015600/1
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3Academic Journal
المؤلفون: Zeeshan, M, Ferguson, DJP, Abel, S, Burrrell, A, Rea, E, Brady, D, Daniel, E, Delves, M, Vaughan, S, Holder, AA, Le Roch, KG, Moores, CA, Tewari, R
المصدر: Life Science Alliance , 2 (4) , Article e201900488. (2019)
وصف الملف: text
Relation: https://discovery.ucl.ac.uk/id/eprint/10081511/1/e201900488.full.pdf; https://discovery.ucl.ac.uk/id/eprint/10081511/
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4Academic Journal
المؤلفون: Delves, M, Lafuente-Monasterio, M, Upton, L, Ruecker, A, Leroy, D, Gamo, F, Sinden, R
Relation: https://ora.ox.ac.uk/objects/uuid:630bed50-85ce-41cb-ab52-4e977c01d84d; https://doi.org/10.3389/fmicb.2019.02134
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5Academic Journal
المؤلفون: Eden Primary, C, Straschil, U, Witmer, K, Delves, M, Marks, S, Baum, J
المساهمون: Wellcome Trust
المصدر: 1142 ; 1138
مصطلحات موضوعية: drug discovery, high throughput screening, malaria, natural compounds, traditional medicine, Children of Eden Primary School, Pediatrics, 1103 Clinical Sciences, 1114 Paediatrics and Reproductive Medicine, 1117 Public Health and Health Services
Relation: Archives of Disease in Childhood; http://hdl.handle.net/10044/1/74544; 100993/Z/13/Z
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6Academic Journal
المؤلفون: Bradley, J, Soumaré, HM, Mahamar, A, Diawara, H, Roh, M, Delves, M, Drakeley, C, Churcher, TS, Dicko, A, Gosling, R, Bousema, T
المساهمون: PATH-Program for Appropriate Technology in Health, Medical Research Council (MRC)
المصدر: 1439 ; 1436
مصطلحات موضوعية: anopheles, infectiousness, malaria, transmission, treatment, Microbiology, 06 Biological Sciences, 11 Medical and Health Sciences
جغرافية الموضوع: United States
Relation: Clinical Infectious Diseases; http://hdl.handle.net/10044/1/69053; https://doi.org/10.1093/cid/ciz134; GAT.0888-30-01618462-COL; MR/R015600/1
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7Academic Journal
المؤلفون: Zeeshan, M., Ferguson, D.J.P., Abel, S., Burrrell, A., Rea, E., Brady, D., Daniel, E., Delves, M., Vaughan, S., Holder, A.A., Le Roch, K.G., Moores, Carolyn A., Tewari, R.
مصطلحات موضوعية: Biological Sciences
وصف الملف: text
Relation: https://eprints.bbk.ac.uk/id/eprint/28561/1/28561.pdf; Zeeshan, M. and Ferguson, D.J.P. and Abel, S. and Burrrell, A. and Rea, E. and Brady, D. and Daniel, E. and Delves, M. and Vaughan, S. and Holder, A.A. and Le Roch, K.G. and Moores, Carolyn A. and Tewari, R. (2019) Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. Life Science Alliance 2 (4), e201900488. ISSN 2575-1077.
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8Academic Journal
المؤلفون: Witmer, K, Sherrard-Smith, E, Straschil, U, Tunnicliff, M, Baum, J, Delves, M
المساهمون: Bill & Melinda Gates Foundation, Wellcome Trust, Medicines for Malaria Venture
مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Infectious Diseases, Parasitology, Tropical Medicine, Malaria, Transmission, Gametocyte, Mosquito, SMFA, PLASMODIUM-FALCIPARUM, BERGHEI, MODELS, 1108 Medical Microbiology
Relation: Malaria Journal; http://hdl.handle.net/10044/1/62725; https://dx.doi.org/10.1186/s12936-018-2436-9; OPP1043501; 100993/Z/13/Z; MMV08/2800
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9Academic Journal
المؤلفون: Delves, M, Miguel-Blanco, C, Matthews, H, Molina, I, Ruecker, A, Yahiya, S, Straschil, U, Abraham, M, Leon-Diaz, ML, Fischer, O, Zubiaurre, A, Brandt, J, Cortes, A, Barnard, A, Fuchter, M, Calderon, F, Winzeler, E, Sinden, R, Herreros, E, Gamo, FJ, Baum, J
المساهمون: Bill & Melinda Gates Foundation, Wellcome Trust, Engineering & Physical Science Research Council (EPSRC)
مصطلحات موضوعية: MD Multidisciplinary
Relation: Nature Communications; http://hdl.handle.net/10044/1/62850; https://dx.doi.org/10.1038/s41467-018-05777-2; OPP1043501; 100993/Z/13/Z; EP/L014580/1
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10Academic Journal
المؤلفون: O'Neill, P, Amewu, R, Charman, S, Sabbani, S, Gnädig, N, Straimer, J, Fidock, D, Shore, E, Roberts, N, Wong, M, Hong, W, Pidathala, C, Riley, C, Murphy, B, Aljayyoussi, G, Gamo, F, Sanz, L, Rodrigues, J, Cortes, C, Herreros, E, Angulo-Barturén, I, Jiménez-Díaz, M, Bazaga, S, Martínez-Martínez, M, Campo, B, Sharma, R, Ryan, E, Shackleford, D, Campbell, S, Smith, D, Wirjanata, G, Noviyanti, R, Price, R, Marfurt, J, Palmer, M, Copple, I, Mercer, A, Ruecker, A, Delves, M, Sinden, R, Siegl, P, Davies, J, Rochford, R, Kocken, C, Zeeman, A, Nixon, G, Biagini, G, Ward, S
Relation: https://ora.ox.ac.uk/objects/uuid:94130dae-9157-461e-bd1b-5489b8674143; https://doi.org/10.1038/ncomms15159
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11Academic Journal
المؤلفون: Williamson, A, Ylioja, P, Robertson, M, Antonova-Koch, Y, Avery, V, Baell, J, Batchu, H, Batra, S, Burrows, J, Bhattacharyya, S, Calderon, F, Charman, S, Clark, J, Crespo, B, Dean, M, Debbert, S, Delves, M, Dennis, A, Deroose, F, Duffy, S, Fletcher, S, Giaever, G, Hallyburton, I, Gamo, F, Gebbia, M, Guy, R, Hungerford, Z, Kirk, K, Lafuente-Monasterio, M, Lee, A, Meister, S, Nislow, C, Overington, J, Papadatos, G, Patiny, L, Pham, J, Ralph, S, Ruecker, A, Ryan, E, Southan, C, Srivastava, K, Swain, C, Tarnowski, M, Thomson, P, Turner, P, Wallace, I, Wells, T, White, K, White, L, Willis, P, Winzeler, E, Wittlin, S, Todd, M
Relation: https://ora.ox.ac.uk/objects/uuid:32cd3d14-3f69-473b-ae1d-94aac7d96e04; https://doi.org/10.1021/acscentsci.6b00086
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12Academic Journal
المؤلفون: Le Bihan, A, de Kanter, R, Angulo-Barturen, I, Binkert, C, Boss, C, Brun, R, Brunner, R, Buchmann, S, Burrows, J, Dechering, K, Delves, M, Ewerling, S, Ferrer, S, Fischli, C, Gamo-Benito, F, Gnädig, N, Heidmann, B, Jiménez-Díaz, M, Leroy, D, Martínez, M, Meyer, S, Moehrle, J, Ng, C, Noviyanti, R, Ruecker, A, Sanz, L, Sauerwein, R, Scheurer, C, Schleiferboeck, S, Sinden, R, Snyder, C, Straimer, J, Wirjanata, G, Marfurt, J, Price, R, Weller, T, Fischli, W, Fidock, D, Clozel, M, Wittlin, S
Relation: https://ora.ox.ac.uk/objects/uuid:cefd75de-e423-41b9-acc8-5bc1ebc0cf7a; https://doi.org/10.1371/journal.pmed.1002138
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13Academic Journal
المؤلفون: Vaidya, AB, Morrisey, J, Zhang, Z, Das, S, Daly, T, Otto, T, Spillman, N, Wyvratt, M, Siegl, P, Marfurt, J, Wirjanata, G, Sebayang, B, Price, R, Chatterjee, A, Nagle, A, Stasiak, M, Charman, SA, Angulo-Barturen, I, Ferrer, S, Belén Jiménez-Díaz, M, Martínez, MS, Gamo, F, Avery, V, Ruecker, A, Delves, M, Kirk, K, Berriman, M, Kortagere, S, Burrows, J, Fan, E, Bergman, L
Relation: https://ora.ox.ac.uk/objects/uuid:96766f26-a9b4-4f8a-9cf3-c500c321e7be; https://doi.org/10.1038/ncomms6521
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14Academic Journal
المؤلفون: Delves, M, Straschil, U, Ruecker, A, Miguel-Blanco, C, Marques, S, Baum, J, Sinden, R
Relation: https://ora.ox.ac.uk/objects/uuid:8398bf2a-4805-48fa-8ad0-e0a1f68befef; https://doi.org/10.1038/nprot.2016.096
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15
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16Academic Journal
المؤلفون: White, N, Ashley, E, Recht, J, Delves, M, Ruecker, A, Smithuis, F, Eziefula, A, Bousema, T, Drakeley, C, Chotivanich, K, Imwong, M, Pukrittayakamee, S, Prachumsri, J, Chu, C, Andolina, C, Bancone, G, Hien, T, Mayxay, M, Taylor, W, von Seidlein, L, Price, R, Barnes, K, Djimdé, A, ter Kuile, F, Gosling, R, Chen, I, Dhorda, M, Stepniewska, K, Guérin, P, Woodrow, C, Dondorp, A, Day, N, Nosten, F
Relation: https://ora.ox.ac.uk/objects/uuid:72435f19-8e28-4725-a93b-6fbabd4c808b; https://doi.org/10.1186/1475-2875-13-483
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17Academic Journal
المؤلفون: Delves, M, Plouffe, D, Scheurer, C, Meister, S, Wittlin, S, Winzeler, E, Sinden, R, Leroy, D
Relation: https://ora.ox.ac.uk/objects/uuid:71a03dd8-6257-4b49-84b7-22733ac9e83b; https://doi.org/10.1371/journal.pmed.1001169
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18Academic Journal
المؤلفون: Williamson, AE, Ylioja, PM, Robertson, MN, Antonova-Koch, Y, Avery, V, Baell, JB, Batchu, H, Batra, S, Burrows, JN, Bhattacharyya, S, Calderon, F, Charman, SA, Clark, J, Crespo, B, Dean, M, Debbert, SL, Delves, M, Dennis, ASM, Deroose, F, Duffy, S, Fletcher, S, Giaever, G, Hallyburton, I, Gamo, F-J, Gebbia, M, Guy, RK, Hungerford, Z, Kirk, K, Lafuente-Monasterio, MJ, Lee, A, Meister, S, Nislow, C, Overington, JP, Papadatos, G, Patiny, L, Pham, J, Ralph, SA, Ruecker, A, Ryan, E, Southan, C, Srivastava, K, Swain, C, Tarnowski, MJ, Thomson, P, Turner, P, Wallace, IM, Wells, TNC, White, K, White, L, Willis, P, Winzeler, EA, Wittlin, S, Todd, MH
المصدر: ACS Central Science , 2 (10) pp. 687-701. (2016)
وصف الملف: text
Relation: https://discovery.ucl.ac.uk/id/eprint/10057284/1/acscentsci.6b00086.pdf; https://discovery.ucl.ac.uk/id/eprint/10057284/
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19Academic Journal
المؤلفون: Van Voorhis, WC, Adams, JH, Adelfio, R, Ahyong, V, Akabas, MH, Alano, P, Alday, A, Alemán Resto, Y, Alsibaee, A, Alzualde, A, Andrews, KT, Avery, SV, Avery, VM, Ayong, L, Baker, M, Baker, S, Ben Mamoun, C, Bhatia, S, Bickle, Q, Bounaadja, L, Bowling, T, Bosch, J, Boucher, LE, Boyom, FF, Brea, J, Brennan, M, Burton, A, Caffrey, CR, Camarda, G, Carrasquilla, M, Carter, D, Belen Cassera, M, Chih-Chien Cheng, K, Chindaudomsate, W, Chubb, A, Colon, BL, Colón-López, DD, Corbett, Y, Crowther, GJ, Cowan, N, D'Alessandro, S, Le Dang, N, Delves, M, DeRisi, JL, Du, AY, Duffy, S, Abd El-Salam El-Sayed, S, Ferdig, MT, Fernández Robledo, JA, Fidock, DA, Florent, I, Fokou, PV, Galstian, A, Gamo, FJ, Gokool, S, Gold, B, Golub, T, Goldgof, GM, Guha, R, Guiguemde, WA, Gural, N, Guy, RK, Hansen, MA, Hanson, KK, Hemphill, A, Hooft van Huijsduijnen, R, Horii, T, Horrocks, P, Hughes, TB, Huston, C, Igarashi, I, Ingram-Sieber, K, Itoe, MA, Jadhav, A, Naranuntarat Jensen, A, Jensen, LT, Jiang, RH, Kaiser, A, Keiser, J, Ketas, T, Kicka, S, Kim, S, Kirk, K, Kumar, VP, Kyle, DE, Lafuente, MJ, Landfear, S, Lee, N, Lee, S, Lehane, AM, Li, F, Little, D, Liu, L, Llinás, M, Loza, MI, Lubar, A, Lucantoni, L, Lucet, I, Maes, L, Mancama, D, Mansour, NR, March, S, McGowan, S, Medina Vera, I, Meister, S, Mercer, L, Mestres, J, Mfopa, AN, Misra, RN, Moon, S, Moore, JP, Morais Rodrigues da Costa, F, Müller, J, Muriana, A, Nakazawa Hewitt, S, Nare, B, Nathan, C, Narraidoo, N, Nawaratna, S, Ojo, KK, Ortiz, D, Panic, G, Papadatos, G, Parapini, S, Patra, K, Pham, N, Prats, S, Plouffe, DM, Poulsen, SA, Pradhan, A, Quevedo, C, Quinn, RJ, Rice, CA, Abdo Rizk, M, Ruecker, A, St Onge, R, Salgado Ferreira, R, Samra, J, Robinett, NG, Schlecht, U, Schmitt, M, Silva Villela, F, Silvestrini, F, Sinden, R, Smith, DA, Soldati, T, Spitzmüller, A, Stamm, SM, Sullivan, DJ, Sullivan, W, Suresh, S, Suzuki, BM, Suzuki, Y, Swamidass, SJ, Taramelli, D, Tchokouaha, LR, Theron, A, Thomas, D, Tonissen, KF, Townson, S, Tripathi, AK, Trofimov, V, Udenze, KO, Ullah, I, Vallieres, C, Vigil, E, Vinetz, JM, Voong Vinh, P, Vu, H, Watanabe, NA, Weatherby, K, White, PM, Wilks, AF, Winzeler, EA, Wojcik, E, Wree, M, Wu, W, Yokoyama, N, Zollo, PH, Abla, N, Blasco, B, Burrows, J, Laleu, B, Leroy, D, Spangenberg, T, Wells, T, Willis, PA
المساهمون: Bill & Melinda Gates Foundation
المصدر: e1005763
مصطلحات موضوعية: Virology, 0605 Microbiology, 1107 Immunology, 1108 Medical Microbiology
Relation: PLOS Pathogens; http://hdl.handle.net/10044/1/38890; https://dx.doi.org/10.1371/journal.ppat.1005763; OPP1043501
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20Academic Journal
المؤلفون: Phillips, M. A., Lotharius, J., Marsh, K., White, J., Dayan, A., White, K. L., Njoroge, J. W., El Mazouni, F., Lao, Y., Kokkonda, S., Tomchick, D. R., Deng, X., Laird, T., Ng, C. L., Fidock, D. A., Wittlin, S., Lafuente-Monasterio, M., Benito, F. J. G., Alonso, L. M. S., Martinez, M. S., Jimenez-Diaz, M. B., Bazaga, S. F., Angulo-Barturen, I., Haselden, J. N., Louttit, J., Cui, Y., Sridhar, A., Zeeman, A.-M., Kocken, C., Sauerwein, R., Dechering, K., Avery, V. M., Duffy, S., Delves, M., Sinden, R., Ruecker, A., Wickham, K. S., Rochford, R., Gahagen, J., Iyer, L., Riccio, E., Mirsalis, J., Bathhurst, I., Rueckle, T., Ding, X., Campo, B., Leroy, D., Rogers, M. J., Rathod, P. K., Burrows, J. N., Charman, S. A., Bhatia, Sangeeta N, March-Riera, Sandra
المساهمون: Massachusetts Institute of Technology. Institute for Medical Engineering & Science, Harvard University--MIT Division of Health Sciences and Technology, Bhatia, Sangeeta N, March-Riera, Sandra
المصدر: PMC
وصف الملف: application/pdf
Relation: http://dx.doi.org/10.1126/scitranslmed.aaa6645; Science Translational Medicine; http://hdl.handle.net/1721.1/110776; Phillips, M. A.; Lotharius, J.; Marsh, K. et al. “A Long-Duration Dihydroorotate Dehydrogenase Inhibitor (DSM265) for Prevention and Treatment of Malaria.” Science Translational Medicine 7, 296 (July 2015): 296ra111 © 2015 American Association for the Advancement of Science; orcid:0000-0002-1293-2097
الاتاحة: http://hdl.handle.net/1721.1/110776
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