نتائج البحث - "Deepti Rokkam"

1

Academic Journal

1053 Preclinical pharmacodynamic characterization of STK-026: a novel IL-12 partial agonist for cancer with maintained CD8 T cell activity, reduced NK-mediated toxicity and an improved therapeutic window

المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/3e0b02efc0da4cb49b22cd8ab1e23832

View record in DOAJ

Full Text Finder

2

Academic Journal

228 Engineered human IL-2/IL-2Rß orthogonal pairs selectively enhance anti-GPC3 CAR T cells in vivo to drive complete responses in solid epithelial tumor models

المؤلفون: Martin Oft, Mohammed Ali, Ryan Burgess, Michele Bauer, Deepti Rokkam, Navneet Ratti, Sandro Vivona, Patrick Lupardus, Paul-Joseph Aspuria, Marie Semana, Ivan Cheng, Mahalaksmi Ramadass, Henry Rosas, George Zheng

المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/161db09967f94eabbee53cd6b0f72813

View record in DOAJ

Full Text Finder

3

Academic Journal

The C. elegans rab family: identification, classification and toolkit construction.

المؤلفون: Maria E Gallegos, Sanjeev Balakrishnan, Priya Chandramouli, Shaily Arora, Aruna Azameera, Anitha Babushekar, Emilee Bargoma, Abdulmalik Bokhari, Siva Kumari Chava, Pranti Das, Meetali Desai, Darlene Decena, Sonia Dev Devadas Saramma, Bodhidipra Dey, Anna-Louise Doss, Nilang Gor, Lakshmi Gudiputi, Chunyuan Guo, Sonali Hande, Megan Jensen, Samantha Jones, Norman Jones, Danielle Jorgens, Padma Karamchedu, Kambiz Kamrani, Lakshmi Divya Kolora, Line Kristensen, Kelly Kwan, Henry Lau, Pranesh Maharaj, Navneet Mander, Kalyani Mangipudi, Himabindu Menakuru, Vaishali Mody, Sandeepa Mohanty, Sridevi Mukkamala, Sheena A Mundra, Sudharani Nagaraju, Rajhalutshimi Narayanaswamy, Catherine Ndungu-Case, Mersedeh Noorbakhsh, Jigna Patel, Puja Patel, Swetha Vandana Pendem, Anusha Ponakala, Madhusikta Rath, Michael C Robles, Deepti Rokkam, Caroline Roth, Preeti Sasidharan, Sapana Shah, Shweta Tandon, Jagdip Suprai, Tina Quynh Nhu Truong, Rubatharshini Uthayaruban, Ajitha Varma, Urvi Ved, Zeran Wang, Zhe Yu

المصدر: PLoS ONE, Vol 7, Iss 11, p e49387 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3504004?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/9e39355a292a4bc0a43e677c2b716029

View record in DOAJ

Full Text Finder

4

Abstract 1801: STK-012, an a/b-selective IL-2 activates tumor antigen specific CD25+ CD8 T cells to reject tumors without acute vascular toxicity

المؤلفون: Martin Oft, Navneet Ratti, Sandro Vivona, Jan Emmerich, Romina Riener, Ievgen O. Koliesnik, Scott McCauley, Michele Bauer, Marie Semana, Deepti Rokkam, Bhargavi Jayaraman, Rene de Waal Malefyt, Paul-Joseph Aspuria, Michael Totagrande, Anita Mehta-Damani, Patrick J. Lupardus, Rob A. Kastelein

المصدر: Cancer Research. 83:1801-1801

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e43a4b8e656e3c87b806bcec92def646
https://doi.org/10.1158/1538-7445.am2023-1801

View record in OpenAIRE

5

Abstract 1833: Novel IL-12 Partial Agonist For Cancer Immunotherapy Avoids NK-cell Mediated Toxicity

المؤلفون: Ievgen Koliesnik, Jan Emmerich, Kim Q. Tran, Michele Bauer, Michael Totagrande, Bhargavi Jayaraman, Cindy Buffone, Priyanka Balasubrahmanyam, Deepti Rokkam, Rene de Waal Malefyt, Luis Zuniga, Heiko Greb, Navneet Ratti, Sandro Vivona, Martin Oft, Patrick J. Lupardus, Robert A. Kastelein

المصدر: Cancer Research. 83:1833-1833

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::43b30cab5d0df1c8a2e56d783686ec2d
https://doi.org/10.1158/1538-7445.am2023-1833

View record in OpenAIRE

6

An orthogonal IL-2 and IL-2Rβ system drives persistence and activation of CAR T cells and clearance of bulky lymphoma

المؤلفون: Paul-Joseph Aspuria, Sandro Vivona, Michele Bauer, Marie Semana, Navneet Ratti, Scott McCauley, Romina Riener, Rene de Waal Malefyt, Deepti Rokkam, Jan Emmerich, Rob A. Kastelein, Patrick J. Lupardus, Martin Oft

المصدر: Science Translational Medicine. 13

مصطلحات موضوعية: Lymphoma, T-Lymphocytes, Antigens, CD19, Receptors, Antigen, T-Cell, Humans, Interleukin-2, General Medicine, Neoplasm Recurrence, Local, Immunotherapy, Adoptive, human activities

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee991caea3f0526827cf9cefb73e6b2
https://doi.org/10.1126/scitranslmed.abg7565

View record in OpenAIRE

7

Abstract 5544: IL10/IL2 surrogate cytokine agonists

المؤلفون: Mahalakshmi Ramadass, Sandro Vivona, Deepti Rokkam, Heiko Greb, Anu Gangopadhyay, Romina Riener, Rene de Waal Malefyt, Patrick Lupardus, Martin Oft, Robert Kastelein

المصدر: Cancer Research. 82:5544-5544

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::98352e812d730e62a7ae67109b3aed28
https://doi.org/10.1158/1538-7445.am2022-5544

View record in OpenAIRE

8

Abstract 2824: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance anti-GPC3 CAR T cells to drive complete responses in solid epithelial tumor models

المؤلفون: Paul-Joseph Aspuria, Marie Semana, Sandro Vivona, Mahalaksmi Ramadass, Navneet Ratti, Romina Riener, Michele Bauer, Mohammed Ali, Deepti Rokkam, Rob A. Kastelein, Patrick J. Lupardus, Martin Oft

المصدر: Cancer Research. 82:2824-2824

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e7a97bf668e19ea462b904189b2ca219
https://doi.org/10.1158/1538-7445.am2022-2824

View record in OpenAIRE

9

Discovery and characterization of llama VHH targeting the RO form of human CD45

المؤلفون: Patrick J. Lupardus, Deepti Rokkam

مصطلحات موضوعية: Fibronectin, Phage display, biology, Chemistry, biology.protein, Protein tyrosine phosphatase, Computational biology, Yeast display, Antibody, In vitro, Function (biology), Domain (software engineering)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c28e7fc10a83f1da37fa0b9475054015
https://doi.org/10.1101/2020.09.01.278853

View record in OpenAIRE

10

Abstract 1744: STK-012, an alpha/beta selective IL-2 mutein for the activation of the antigen-activated T cells in solid tumor

المؤلفون: Scott Alan Mccauley, Rob A. Kastelein, Jan Emmerich, Romina Riener, Bhargavi Jayaraman, Sandro Vivona, Patrick J. Lupardus, Deepti Rokkam, Michele Bauer, Marie Semana, Rene de Waal Malefyt, Martin Oft, Paul-Joseph Aspuria

المصدر: Cancer Research. 81:1744-1744

مصطلحات موضوعية: Cancer Research, Oncology, Antigen, Chemistry, Alpha (ethology), Beta (finance), Solid tumor, Molecular biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e0629afb8428de24291343fce7bd37f8
https://doi.org/10.1158/1538-7445.am2021-1744

View record in OpenAIRE

11

Abstract 1512: OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumor efficacy by driving T cell expansion and fitness

المؤلفون: Romina Riener, Paul-Joseph Aspuria, Jan Emmerich, Navneet Ratti, Marie Semana, Deepti Rokkam, Sandro Vivona, Rob A. Kastelein, Rene de Waal Malefyt, Martin Oft, Scott Alan Mccauley, Michele Bauer, Patrick J. Lupardus

المصدر: Cancer Research. 81:1512-1512

مصطلحات موضوعية: Cancer Research, medicine.anatomical_structure, Oncology, Chemistry, T cell, medicine, Car t cells, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9c9214b2dd01562e46fb27a9f7bdc2f3
https://doi.org/10.1158/1538-7445.am2021-1512

View record in OpenAIRE

12

OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumorefficacy

المؤلفون: Romina Riener, Scott Alan Mccauley, Jan Emmerich, Deepti Rokkam, Steven E. Kauder, Rene de Waal Malefyt, Rakesh Verma, Rob A. Kastelein, Sandro Vivona, Michael A Bauer, Martin Oft, Paul-Joseph Aspuria

المصدر: Blood. 136:35-35

مصطلحات موضوعية: Chemistry, Immunology, Cell Biology, Hematology, Car t cells, Biochemistry, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8d3767dd92fc15ab449049010930ae4a
https://doi.org/10.1182/blood-2020-143483

View record in OpenAIRE

13

Abstract 3252: OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell anti-tumor efficacy and durability of response

المؤلفون: Steven E. Kauder, Rob A. Kastelein, Michele Bauer, Jan Emmerich, Patrick J. Lupardus, Romina Riener, Rene De Waal Malefyte, Deepti Rokkam, Paul-Joseph Aspuria, Sandro Vivona, Scott Alan Mccauley, Martin Oft, Navneet Ratti

المصدر: Cancer Research. 80:3252-3252

مصطلحات موضوعية: Cancer Research, biology, Chemistry, medicine.medical_treatment, T cell, CD19, Granzyme B, Cytokine, medicine.anatomical_structure, Immune system, Oncology, Cancer research, medicine, biology.protein, Cytotoxic T cell, CD8, B cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::836f173deccaf826eb308893cd0b7c5b
https://doi.org/10.1158/1538-7445.am2020-3252

View record in OpenAIRE

14

A Role For Lung-Specific Tight Junction Protein Claudin-18 In Alveolar Epithelial Barrier Function

المؤلفون: Leland G. Dobbs, Deepti Rokkam, Lennell Allen, Katherine M. Sutherland, James A. Frank, Michael J. LaFemina, Trevor Bentley

المصدر: A62. NEW INSIGHTS IN ACUTE LUNG INJURY: IN VIVO AND IN VITRO.

مصطلحات موضوعية: Lung, medicine.anatomical_structure, Tight junction, Chemistry, medicine, Epithelial barrier function, Claudin, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::78fc75a6e434e234a1d93e66bd66c69d
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6740

View record in OpenAIRE

15

Claudin-4 Levels Are Associated with Intact Alveolar Fluid Clearance in Human Lungs

المؤلفون: Jae-Woo Lee, James A. Frank, Deepti Rokkam, Michael J. LaFemina, Michael A. Matthay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcd89f659318671c993d1dc2bbe3307
https://europepmc.org/articles/PMC3157178/

View record in OpenAIRE

16

Bronchoalveolar Lavage Fluid From Patients With Acute Lung Injury Alters Barrier Function In Primary Alveolar Epithelial Cell Monolayers

المؤلفون: James A. Frank, Michael J. LaFemina, Michael A. Matthay, Deepti Rokkam, Trevor Bentley

المصدر: C67. ALVEOLAR EPITHELIUM.

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Bronchoalveolar lavage, medicine.diagnostic_test, business.industry, Alveolar epithelial cell, Immunology, Medicine, Lung injury, business, Barrier function

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2cd9ddc12bb796879d7f6891fdb5a07b
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5096

View record in OpenAIRE

17

Claudin‐4 promotes repair and barrier function in lung epithelia

المؤلفون: Jan Hirsch, Gwen Ho, James A. Frank, Chris Griffin, Michael J. LaFemina, Deepti Rokkam

المصدر: The FASEB Journal. 25

مصطلحات موضوعية: Lung, medicine.anatomical_structure, Chemistry, Genetics, Cancer research, medicine, Claudin, Molecular Biology, Biochemistry, Barrier function, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cc9d28751208eac5da03cda2a2680438
https://doi.org/10.1096/fasebj.25.1_supplement.865.6

View record in OpenAIRE

18

Keratinocyte growth factor enhances barrier function without altering claudin expression in primary alveolar epithelial cells

المؤلفون: Anita Chandrasena, Deepti Rokkam, James A. Frank, Jue Pan, Meshell D. Johnson, Anisha Bajaj, Michael J. LaFemina

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc19bf23d008aa9eae34f10675745b6e
https://europepmc.org/articles/PMC3006268/

View record in OpenAIRE

19

Claudin-4 Expression And Trafficking In Alveolar Epithelial Repair

المؤلفون: Gwendolyn Ho, James A. Frank, Anisha Bajaj, Deepti Rokkam, Michael A. Matthay, Jae Won Lee

المصدر: B65. MECHANISMS OF LUNG INJURY AND REPAIR.

مصطلحات موضوعية: Biology, Claudin, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb4eb3abc716d29355711c3c4a64f22c
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3550

View record in OpenAIRE

20

Tobacco Smoke Exposure And Mechanical Ventilation Induce Alterations In The Rat Alveolar Type II Cell Proteome

المؤلفون: Deepti Rokkam, Jan Hirsch, Robert J. Chalkley, Alma L. Burlingame, James A. Frank

المصدر: D65. FUNCTIONAL GENOMICS/PROTEOMICS OF DISEASE PATHOGENESIS.

مصطلحات موضوعية: Mechanical ventilation, Pathology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Immunology, Tobacco smoke exposure, Proteome, Medicine, Alveolar type II cell, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a38d82b2792d0c5d0f16d0603534d5e7
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6404

View record in OpenAIRE

تنقيح النتائج