نتائج البحث - "Debora Schmitz-Rohmer"

1

Academic Journal

A Phase II Study to Assess the Safety and Efficacy of the Dual mTORC1/2 and PI3K Inhibitor Bimiralisib (PQR309) in Relapsed, Refractory Lymphoma

المصدر: HemaSphere, Vol 5, Iss 11, p e656 (2021)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000656; https://doaj.org/toc/2572-9241

URL الوصول: https://doaj.org/article/8e18548fde2a404c9bbf77be27391d61

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2

Academic Journal

NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development.

المؤلفون: Debora Schmitz-Rohmer, Simone Probst, Zhong-Zhou Yang, Frédéric Laurent, Michael B Stadler, Aimée Zuniga, Rolf Zeller, Debby Hynx, Brian A Hemmings, Alexander Hergovich

المصدر: PLoS ONE, Vol 10, Iss 8, p e0136566 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4549247?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/654538069ff24c9aa7e82c33a337670c

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3

Academic Journal

Correction: Wind et al. Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial. Cancers 2022, 14, 1510

المصدر: Cancers; Volume 15; Issue 5; Pages: 1485

مصطلحات موضوعية: n/a

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers15051485

الاتاحة: https://doi.org/10.3390/cancers15051485

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4

Academic Journal

Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial

المصدر: Cancers; Volume 14; Issue 6; Pages: 1510

مصطلحات موضوعية: CTCL, mycosis fungoides, pharmacokinetics, bimiralisib, PQR309, PI3K/mTOR

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers14061510

الاتاحة: https://doi.org/10.3390/cancers14061510

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5

Supplementary Figure 1 from hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme

المؤلفون: Debora Schmitz-Rohmer, Brian A. Hemmings, Stephan Frank, Alexander Hergovich, Christian Hundsrucker, Peter D. Cron, Yuhua Wang, Debby Hynx, Gongda Xue, Lei Zhang, Fengyuan Tang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3bb092da52ca76ba0dc8409729fe94
https://doi.org/10.1158/0008-5472.22404285

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6

Supplementary Figure 2 from hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme

المؤلفون: Debora Schmitz-Rohmer, Brian A. Hemmings, Stephan Frank, Alexander Hergovich, Christian Hundsrucker, Peter D. Cron, Yuhua Wang, Debby Hynx, Gongda Xue, Lei Zhang, Fengyuan Tang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40954a3afa2be28bdf9ce83a7d27aeb5
https://doi.org/10.1158/0008-5472.22404279

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7

Supplementary Figure 3 from hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme

المؤلفون: Debora Schmitz-Rohmer, Brian A. Hemmings, Stephan Frank, Alexander Hergovich, Christian Hundsrucker, Peter D. Cron, Yuhua Wang, Debby Hynx, Gongda Xue, Lei Zhang, Fengyuan Tang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233b9d1d3af578c7805bf38348f86616
https://doi.org/10.1158/0008-5472.22404276

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8

Data from hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme

المؤلفون: Debora Schmitz-Rohmer, Brian A. Hemmings, Stephan Frank, Alexander Hergovich, Christian Hundsrucker, Peter D. Cron, Yuhua Wang, Debby Hynx, Gongda Xue, Lei Zhang, Fengyuan Tang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6b6b33904a163ab0e191517dc0edd9
https://doi.org/10.1158/0008-5472.c.6506568.v1

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9

Supplementary Materials and Methods, Figure Legends from hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme

المؤلفون: Debora Schmitz-Rohmer, Brian A. Hemmings, Stephan Frank, Alexander Hergovich, Christian Hundsrucker, Peter D. Cron, Yuhua Wang, Debby Hynx, Gongda Xue, Lei Zhang, Fengyuan Tang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214c91c2e828fccde1d0221d4dbb084f
https://doi.org/10.1158/0008-5472.22404273.v1

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10

A Phase II Study to Assess the Safety and Efficacy of the Dual mTORC1/2 and PI3K Inhibitor Bimiralisib (PQR309) in Relapsed, Refractory Lymphoma

المصدر: HemaSphere
HemaSphere, Vol 5, Iss 11, p e656 (2021)

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Phases of clinical research, Hematology, mTORC1, medicine.disease, Article, Lymphoma, Internal medicine, Relapsed refractory, medicine, Diseases of the blood and blood-forming organs, RC633-647.5, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32419b1a2a0f2276e7b7d9c2a0febb6
https://doi.org/10.1097/hs9.0000000000000656

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11

18572 Relevant skin exposure after topical application of the pan-PI3K/mTOR inhibitor bimiralisib

المؤلفون: Raphael Legouffe, Melanie Rolli, Robert Rissmann, Maarten H. Vermeer, Debora Schmitz-rohmer, Henk Johann Streefkerk

المصدر: Journal of the American Academy of Dermatology. 83:AB102

مصطلحات موضوعية: business.industry, Skin exposure, Medicine, Dermatology, Pharmacology, Discovery and development of mTOR inhibitors, business, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d8796dd97f42c49f68b39a346e582b17
https://doi.org/10.1016/j.jaad.2020.06.496

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12

NDR Functions as a Physiological YAP1 Kinase in the Intestinal Epithelium

المؤلفون: Sandrine Bichet, Alexander Hergovich, Luigi Terracciano, Daniel Hess, Lei Zhang, Fengyuan Tang, Peter Cron, Brian A. Hemmings, Debora Schmitz-Rohmer, Debby Hynx, Reto S. Kohler

المصدر: Current Biology

مصطلحات موضوعية: Blotting, Western, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Intestinal mucosa, Serine, Animals, Humans, Intestinal Mucosa, Phosphorylation, Adaptor Proteins, Signal Transducing, Cell Proliferation, 030304 developmental biology, Mice, Knockout, YAP1, Regulation of gene expression, 0303 health sciences, Protein-Serine-Threonine Kinases, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Kinase, Histological Techniques, YAP-Signaling Proteins, Microarray Analysis, Phosphoproteins, Intestinal epithelium, Molecular biology, 3. Good health, Cell biology, Gene Expression Regulation, Neoplastic, Mice, Inbred C57BL, Hippo signaling, 030220 oncology & carcinogenesis, General Agricultural and Biological Sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c80b7f26aa7cbc2055d87cf2732c52
https://doi.org/10.1016/j.cub.2014.11.054

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13

The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility

المؤلفون: Hauke Cornils, Dawang Zhou, Gongda Xue, Patrick Matthias, Xenia Ficht, Zhongzhou Yang, Thomas Barthlott, Jason Gill, Fengyuan Tang, Jens V. Stein, Debby Hynx, Georg A Hollaender, Brian A. Hemmings, Michal Grzmil, Lei Zhang, Alexander Hergovich, Debora Schmitz-Rohmer

المصدر: Science Signaling
Science signaling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed165d304ab7d0cff7b1d5a209d7b3d
https://ora.ox.ac.uk/objects/uuid:cb3d0fd2-cac8-4a57-9cf3-46d5d6cf313c

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14

hMOB3 modulates MST1 apoptotic signaling and supports tumor growth in glioblastoma multiforme

المؤلفون: Christian Hundsrucker, Yuhua Wang, Gongda Xue, Brian A. Hemmings, Lei Zhang, Debora Schmitz-Rohmer, Stephan Frank, Fengyuan Tang, Debby Hynx, Peter Cron, Alexander Hergovich

المصدر: Cancer Research

مصطلحات موضوعية: Cancer Research, MST1, Gene Expression, Apoptosis, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Animals, Humans, Protein kinase A, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Hippo signaling pathway, Cell growth, Hepatocyte Growth Factor, Signal transducing adaptor protein, Immunohistochemistry, 3. Good health, Cell biology, nervous system diseases, Tumor Burden, Disease Models, Animal, Oncology, 030220 oncology & carcinogenesis, Proteolysis, Cancer research, Heterografts, Hepatocyte growth factor, Signal transduction, Glioblastoma, Microtubule-Associated Proteins, medicine.drug, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16acb3ec33c0acea682f84b07f7013a
https://pubmed.ncbi.nlm.nih.gov/24872389

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