المؤلفون: Li, Wenkui, Vazvaei‐Smith, Faye, Dear, Gordon, Boer, Jason, Cuyckens, Filip, Fraier, Daniela, Liang, Yuexia, Lu, Ding, Mangus, Heidi, Moliner, Patricia, Pedersen, Mette Lund, Romeo, Andrea A., Spracklin, Douglas K., Wagner, David S., Winter, Serge, Xu, Xiaohui (Sophia)

المصدر: Clinical Pharmacology & Therapeutics ; volume 115, issue 5, page 939-953 ; ISSN 0009-9236 1532-6535

الاتاحة: http://dx.doi.org/10.1002/cpt.3144
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.3144

المؤلفون: Miao, Xiusheng, Dear, Gordon J., Beaumont, Claire, Vitulli, Giovanni, Collins, Gary, Gorycki, Peter D., Harrell, Andrew W., Sakatis, Melanie Z.

المصدر: Chemical Research in Toxicology ; volume 37, issue 5, page 698-710 ; ISSN 0893-228X 1520-5010

الاتاحة: http://dx.doi.org/10.1021/acs.chemrestox.3c00402
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.3c00402

المؤلفون: Cahn, Anthony, Hamblin, J. Nicole, Robertson, Jon, Begg, Malcolm, Jarvis, Emily, Wilson, Robert, Dear, Gordon, Leemereise, Claudia, Cui, Yi, Mizuma, Maki, Montembault, Mickael, Van Holsbeke, Cedric, Vos, Wim, De Backer, Wilfried A.K., De Backer, Jan, Hessel, Edith M.

المصدر: 1176-9106 ; International journal of chronic obstructive pulmonary disease

مصطلحات موضوعية: Human medicine

Relation: info:eu-repo/semantics/altIdentifier/isi/000662306700001

الاتاحة: https://hdl.handle.net/10067/1796210151162165141
https://repository.uantwerpen.be/docstore/d:irua:7269

المؤلفون: Cahn,Anthony, Hamblin,J Nicole, Robertson,Jon, Begg,Malcolm, Jarvis,Emily, Wilson,Robert, Dear,Gordon, Leemereise,Claudia, Cui,Yi, Mizuma,Maki, Montembault,Mickael, Van Holsbeke,Cedric, Vos,Wim, De Backer,Wilfried, De Backer,Jan, Hessel,Edith M

مصطلحات موضوعية: International Journal of Chronic Obstructive Pulmonary Disease

وصف الملف: text/html

Relation: https://www.dovepress.com/an-inhaled-pi3k-inhibitor-improves-recovery-in-acutely-exacerbating-co-peer-reviewed-fulltext-article-COPD

الاتاحة: https://www.dovepress.com/an-inhaled-pi3k-inhibitor-improves-recovery-in-acutely-exacerbating-co-peer-reviewed-fulltext-article-COPD

المؤلفون: Beilmann, Mario, Boonen, Harrie, Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Newham, Peter, Oinonen, Teija, Pognan, Francois, Roth, Adrian, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J, Birk, Barbara, Boyer, Scott, Caloni, Francesca, Chen, Alice E, Corvi, Raffaella, Cronin, Mark T D, Daneshian, Mardas, Ewart, Lorna C, Fitzgerald, Rex E, Hamilton, Geraldine A, Hartung, Thomas, Kangas, Joshua D, Kramer, Nynke I, Leist, Marcel, Marx, Uwe, Polak, Sebastian, Rovida, Costanza, Testai, Emanuela, Van der Water, Bob, Vulto, Paul, Steger-Hartmann, Thomas

المساهمون: One Health Toxicologie, dIRAS RA-1

وصف الملف: image/pdf

Relation: https://dspace.library.uu.nl/handle/1874/381420

الاتاحة: https://dspace.library.uu.nl/handle/1874/381420

المؤلفون: Newham, Peter, Steger-Hartmann, Thomas, Beilmann, Mario, Dear, Gordon, Valentin, Jean-Pierre, Hewitt, Philip, Pognan, Francois

Relation: Newham, Peter, Steger-Hartmann, Thomas, Beilmann, Mario, Dear, Gordon, Valentin, Jean-Pierre, Hewitt, Philip and Pognan, Francois (2023) The evolving role of investigative toxicology in the pharmaceutical industry. Nature reviews drug discovery. ISSN 1474-1784; 1474-1776

الاتاحة: https://oak.novartis.com/29713/
https://www.nature.com/articles/s41573-022-00633-x
https://doi.org/10.1038/s41573-022-00633-x

المؤلفون: Richards, Josh E., Hooper, Alexander J.J., Bayfield, Oliver W., Cockett, Martin C.R., Dear, Gordon J., Holmes, A. Jonathon, John, Richard O., Mewis, Ryan E., Pridmore, Natalie, Roberts, Andy D., Whitwood, Adrian C., Duckett, Simon B.

وصف الملف: text

Relation: https://eprints.whiterose.ac.uk/135426/1/quinrevacceptchange.pdf; Richards, Josh E., Hooper, Alexander J.J., Bayfield, Oliver W. et al. (9 more authors) (2018) Using hyperpolarised NMR and DFT to rationalise the unexpected hydrogenation of quinazoline to 3,4-dihydroquinazoline. Chemical Communications. pp. 10375-10378. ISSN 1364-548X

الاتاحة: https://eprints.whiterose.ac.uk/135426/
https://eprints.whiterose.ac.uk/135426/1/quinrevacceptchange.pdf
https://doi.org/10.1039/C8CC04826F

المؤلفون: Weston, Daniel J., Dave, Mehul, Colizza, Kevin, Thomas, Steve, Tomlinson, Laura, Gregory, Richard, Beaumont, Claire, Pirhalla, Jill, Dear, Gordon J.

المصدر: Xenobiotica ; volume 52, issue 8, page 928-942 ; ISSN 0049-8254 1366-5928

الاتاحة: http://dx.doi.org/10.1080/00498254.2022.2136042
https://www.tandfonline.com/doi/pdf/10.1080/00498254.2022.2136042

المؤلفون: Connolly, John R. F. B., Munoz-Muriedas, Jordi, Lapthorn, Cris, Higton, David, Vissers, Johannes P. C., Webb, Alison, Beaumont, Claire, Dear, Gordon J.

المصدر: Journal of the American Society for Mass Spectrometry ; volume 32, issue 8, page 1976-1986 ; ISSN 1044-0305 1879-1123

الاتاحة: http://dx.doi.org/10.1021/jasms.0c00427
https://pubs.acs.org/doi/pdf/10.1021/jasms.0c00427

المؤلفون: Pognan, Francois, Beilmann, Mario, Boonen, Harrie C. M., Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Oinonen, Teija, Roth, Adrian, Steger-Hartmann, Thomas, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J., Newham, Peter

المصدر: Nature Reviews Drug Discovery; April 2023, Vol. 22 Issue: 4 p317-335, 19p

المؤلفون: Nedderman, Angus N.R., Dear, Gordon J., North, Stephanie, Obach, R. Scott, Higton, David

المصدر: Xenobiotica ; volume 41, issue 8, page 605-622 ; ISSN 0049-8254 1366-5928

الاتاحة: http://dx.doi.org/10.3109/00498254.2011.562330
http://www.tandfonline.com/doi/pdf/10.3109/00498254.2011.562330

المؤلفون: Tailor, Arun, Meng, Xiaoli, Adair, Kareena, Farrell, John, Waddington, James C, Daly, Ann, Pirmohamed, Munir, Dear, Gordon, Park, B Kevin, Naisbitt, Dean J

وصف الملف: text

Relation: http://livrepository.liverpool.ac.uk/3102854/3/TOXSCI-20-0262.R1_Proof_hi.pdf; Tailor, Arun, Meng, Xiaoli orcid:0000-0002-7774-2075 , Adair, Kareena orcid:0000-0001-9884-2094 , Farrell, John orcid:0000-0002-8726-5997 , Waddington, James C orcid:0000-0003-2641-5055 , Daly, Ann, Pirmohamed, Munir orcid:0000-0002-7534-7266 , Dear, Gordon, Park, B Kevin orcid:0000-0001-8384-824X and Naisbitt, Dean J (2020) HLA DaB1*15:01-DQB1*06:02-Restricted Human CD4+T Cells Are Selectively Activated With Amoxicillin-Peptide Adducts. TOXICOLOGICAL SCIENCES, 178 (1). pp. 115-126.

الاتاحة: http://livrepository.liverpool.ac.uk/3102854/
https://doi.org/10.1093/toxsci/kfaa128
http://livrepository.liverpool.ac.uk/3102854/3/TOXSCI-20-0262.R1_Proof_hi.pdf

المؤلفون: BEILMANN M., BOONEN Harrie, CZICH Andreas, DEAR Gordon, HEWITT Philip, MOW Thomas, NEWHAM Peter, OINONEN Teija, POGNAN Francois, ROTH Adrian, VALENTIN Jean-Pierre, VAN GOETHEM Freddy, WEAVER R. J., BIRK Barbara, BOYER Scott, CALONI Francesca, CHEN Alice, CORVI Raffaella, CRONIN Mark, DANESHIAN Mardas, EWART Lorna C., FITZGERALD Rex, HAMILTON Geraldine, HARTUNG T., KANGAS Joshua D., KRAMER Nynke, LEIST Marcel, MARX Uwe, POLAK Sebastian, ROVIDA Costanza, TESTAI Emanuela, VAN DE WATER Bob, VULTO Paul, STEGER-HARTMANN Thomas

مصطلحات موضوعية: eco, envir

Relation: https://publications.jrc.ec.europa.eu/repository/handle/JRC112900

الاتاحة: https://publications.jrc.ec.europa.eu/repository/handle/JRC112900

المؤلفون: Tailor, Arun, Waddington, James C., Hamlett, Jane, Maggs, James, Kafu, Laila, Farrell, John, Dear, Gordon J., Whitaker, Paul, Naisbitt, Dean J., Park, Kevin, Meng, Xiaoli

المساهمون: Medical Research Council, GlaxoSmithKline

المصدر: Chemical Research in Toxicology ; volume 32, issue 10, page 2095-2106 ; ISSN 0893-228X 1520-5010

الاتاحة: http://dx.doi.org/10.1021/acs.chemrestox.9b00282
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.9b00282

المؤلفون: Beilmann, Mario, Boonen, Harrie, Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Newham, Peter, Oinonen, Teija, Pognan, Francois, Roth, Adrian, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J, Birk, Barbara, Boyer, Scott, Caloni, Francesca, Chen, Alice E, Corvi, Raffaella, Cronin, Mark T D, Daneshian, Mardas, Ewart, Lorna C, Fitzgerald, Rex E, Hamilton, Geraldine A, Hartung, Thomas, Kangas, Joshua D, Kramer, Nynke I, Leist, Marcel, Marx, Uwe, Polak, Sebastian, Rovida, Costanza, Testai, Emanuela, Van der Water, Bob, Vulto, Paul, Steger-Hartmann, Thomas, One Health Toxicologie, dIRAS RA-1

المساهمون: One Health Toxicologie, dIRAS RA-1

المصدر: ALTEX : Alternatives to Animal Experimentation, 36(2), 289-313
Altex, 36(2), 289. Springer International Publishing AG
ALTEX
ALTEX : Alternatives to Animal Experimentation

مصطلحات موضوعية: 0301 basic medicine, Engineering, Drug Industry, Emerging technologies, Alternatives to animal testing, Drug Evaluation, Preclinical, In Vitro Techniques, Animal Testing Alternatives, Toxicology, Risk Assessment, 03 medical and health sciences, ddc:570, Drug Discovery, Animals, Humans, Computer Simulation, Pharmaceutical industry, Pharmacology, Flexibility (engineering), Animal Welfare (journal), business.industry, Drug discovery, General Medicine, 3. Good health, Europe, Medical Laboratory Technology, 030104 developmental biology, Regulatory toxicology, business, Good laboratory practice

وصف الملف: application/pdf; image/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb64dc6fe72ce1d9d6a38f319e0ce082
http://hdl.handle.net/1887/67901

المؤلفون: Campuzano Iain, Dear Gordon, Etsuko Suzuki, Gordon Dear, Iain Campuzano, Jayne Kirk, Jonathan Williams, Jordi Munoz-Muriedas, Kirk Jayne, Motoji Oshikata, Munoz-Muriedas Jordi, Williams Jonathan, Yukari Haramaki, 押方 基二, 腹巻 ゆかり, 鈴木 悦子

المصدر: Abstracts of Annual meeting of Japanese Society for the Study of Xenobiotics. 2010, :237

المؤلفون: One Health Toxicologie, dIRAS RA-1, Beilmann, Mario, Boonen, Harrie, Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Newham, Peter, Oinonen, Teija, Pognan, Francois, Roth, Adrian, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J, Birk, Barbara, Boyer, Scott, Caloni, Francesca, Chen, Alice E, Corvi, Raffaella, Cronin, Mark T D, Daneshian, Mardas, Ewart, Lorna C, Fitzgerald, Rex E, Hamilton, Geraldine A, Hartung, Thomas, Kangas, Joshua D, Kramer, Nynke I, Leist, Marcel, Marx, Uwe, Polak, Sebastian, Rovida, Costanza, Testai, Emanuela, Van der Water, Bob, Vulto, Paul, Steger-Hartmann, Thomas

URL: https://doi.org/10.14573/altex.1808181
http://hdl.handle.net/1874/381420
https://dspace.library.uu.nl/handle/1874/381420
1868-596X
Altex
36
2
289
313

المؤلفون: Pognan, Francois, Beilmann, Mario, Boonen, Harrie, Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Newham, Peter, Oinonen, Teija, Roth, Adrian, Valentin, Jean-Pierre, van Goethem, Freddy, Weaver, Richard

Relation: Pognan, Francois, Beilmann, Mario, Boonen, Harrie, Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Newham, Peter, Oinonen, Teija, Roth, Adrian, Valentin, Jean-Pierre, van Goethem, Freddy and Weaver, Richard (2018) Optimizing drug discovery by Investigative Toxicology: Current and future trends – Report of CAAT-ITL Forum Think Tank. ALTEX, 36 (2). pp. 289-313.

الاتاحة: https://oak.novartis.com/37258/
https://www.altex.org/index.php/altex/article/view/1163/1280

المؤلفون: Usui, Toru, Tailor, Arun, Faulkner, Lee, Meng, Xiaoli, Farrell, John, Daly, Ann K., Dear, Gordon J., Park, B. Kevin, Naisbitt, Dean J.

المساهمون: Medical Research Council, European Commission, GlaxoSmithKline, European Federation of Pharmaceutical Industries and Associations

المصدر: Chemical Research in Toxicology ; volume 31, issue 10, page 1022-1024 ; ISSN 0893-228X 1520-5010

الاتاحة: http://dx.doi.org/10.1021/acs.chemrestox.8b00163
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.8b00163

المؤلفون: Tailor, Arun, Meng, Xiaoli, Adair, Kareena, Farrell, John, Waddington, James C, Daly, Ann, Pirmohamed, Munir, Dear, Gordon, Park, B Kevin, Naisbitt, Dean J

المصدر: Toxicological Sciences; Nov2020, Vol. 178 Issue 1, p115-126, 12p

مصطلحات موضوعية: T cells, INTERFERON gamma, AMINO acid sequence, BLOOD cells, PEPTIDE derivatives, DNA adducts, HLA histocompatibility antigens, HAPLOTYPES