المؤلفون: Yuri Frosi, Yen-Chu Lin, Jiang Shimin, Siti Radhiah Ramlan, Kelly Hew, Alf Henrik Engman, Anil Pillai, Kit Yeung, Yue Xiang Cheng, Tobias Cornvik, Par Nordlund, Megan Goh, Dilraj Lama, Zachary P. Gates, Chandra S. Verma, Dawn Thean, David P. Lane, Ignacio Asial, Christopher J. Brown

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e93e759ee68a4352930b901a4ebc4c2b

المؤلفون: Yuri Frosi, Rachael Usher, Dawn Thean Gek Lian, David P. Lane, Christopher J. Brown

المصدر: BMC Biology, Vol 17, Iss 1, Pp 1-19 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12915-019-0658-0; https://doaj.org/toc/1741-7007

URL الوصول: https://doaj.org/article/02b7214c71e0425b9cdc9fb8f1f25c8a

المؤلفون: Anthony W. Partridge, Hung Yi Kristal Kaan, Yu-Chi Juang, Ahmad Sadruddin, Shuhui Lim, Christopher J. Brown, Simon Ng, Dawn Thean, Fernando Ferrer, Charles Johannes, Tsz Ying Yuen, Srinivasaraghavan Kannan, Pietro Aronica, Yaw Sing Tan, Mohan R. Pradhan, Chandra S. Verma, Jerome Hochman, Shiying Chen, Hui Wan, Sookhee Ha, Brad Sherborne, David P. Lane, Tomi K. Sawyer

المصدر: Molecules, Vol 24, Iss 12, p 2292 (2019)

مصطلحات موضوعية: peptide permeability, stapled peptide, macrocyclic peptide, D-amino acid, helix-breaker, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/12/2292; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/76dd0b05d6584b64a066db0da685651e

المؤلفون: Sharon Min Qi Chee, Jantana Wongsantichon, Jiawei Siau, Dawn Thean, Fernando Ferrer, Robert C Robinson, David P Lane, Christopher J Brown, Farid J Ghadessy

المصدر: PLoS ONE, Vol 12, Iss 12, p e0189379 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5724825?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/fdc2d7bd24ff4e5e8f8b236a8417e65d

المؤلفون: Andrea Peier (7355747), Lan Ge (460913), Nicolas Boyer (1811797), John Frost (10099766), Ruchia Duggal (10099769), Kaustav Biswas (1693591), Scott Edmondson (10099772), Jeffrey D. Hermes (2135809), Lin Yan (53104), Chad Zimprich (2433892), Ahmad Sadruddin (8804798), Hung Yi Kristal Kaan (10099775), Arun Chandramohan (2813848), Christopher J. Brown (128374), Dawn Thean (3068724), Xue Er Lee (10099778), Tsz Ying Yuen (3068730), Fernando J. Ferrer-Gago (8804801), Charles W. Johannes (1617154), David P. Lane (128368), Brad Sherborne (1296012), Cesear Corona (2363218), Matthew B. Robers (1290444), Tomi K. Sawyer (2356600), Anthony W. Partridge (2446141)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Physiology, Pharmacology, Biotechnology, Immunology, Cancer, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, macrocyclic peptides, membrane translocation, peptide sequence, High Throughput, membrane permeability, design rules, concentration-dependent manner, in-cell Click chemistry, NanoClick assay, target-agnostic cell permeability assay, measure uptake, peptide permeability, intracellular NanoBRET signal, PPI, Target-Agnostic Peptide Cell Permea., high-throughput assays, molecule

Relation: https://figshare.com/articles/journal_contribution/NanoClick_A_High_Throughput_Target-Agnostic_Peptide_Cell_Permeability_Assay/13718000

الاتاحة: https://doi.org/10.1021/acschembio.0c00804.s001

المؤلفون: Kannan, Srinivasaraghavan, Aronica, Pietro G. A., Ng, Simon, Gek Lian, Dawn Thean, Frosi, Yuri, Chee, Sharon, Shimin, Jiang, Yuen, Tsz Ying, Sadruddin, Ahmad, Kaan, Hung Yi Kristal, Chandramohan, Arun, Wong, Jin Huei, Tan, Yaw Sing, Chang, Zi Wei, Ferrer-Gago, Fernando J., Arumugam, Prakash, Han, Yi, Chen, Shiying, Rénia, Laurent, Brown, Christopher J., Johannes, Charles W., Henry, Brian, Lane, David P., Sawyer, Tomi K., Verma, Chandra S., Partridge, Anthony W.

المساهمون: Agency for Science, Technology and Research

المصدر: Chemical Science ; volume 11, issue 21, page 5577-5591 ; ISSN 2041-6520 2041-6539

الاتاحة: http://dx.doi.org/10.1039/c9sc06383h
http://pubs.rsc.org/en/content/articlepdf/2020/SC/C9SC06383H

المؤلفون: David J. Diller, Jon Swanson, Alexander S. Bayden, Chris J. Brown, Dawn Thean, David P. Lane, Anthony W. Partridge, Tomi K. Sawyer, Joseph Audie

المصدر: Molecules; Volume 24; Issue 24; Pages: 4586

مصطلحات موضوعية: peptide design, free energy calculation, d-amino acid scan, alanine scan

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules24244586

الاتاحة: https://doi.org/10.3390/molecules24244586

المؤلفون: Charles W. Johannes, Dawn Thean, Joe R Cannon, Raymond Evers, Tanvi Desai, Hung Yi Kristal Kaan, David P. Lane, Christopher J. Brown, Ahmad Sadruddin, Anthony W. Partridge, Tsz Ying Yuen, Arun Chandramohan, Tomi K. Sawyer, Jerome Hochman, Bahanu Habulihaz

المصدر: Pharmaceutical Research. 38:843-850

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Liposome, Membrane permeability, Organic Chemistry, Pharmaceutical Science, Peptide, 02 engineering and technology, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biotin, chemistry, Permeability (electromagnetism), Biotinylation, Phosphatidylcholine, Click chemistry, Biophysics, Molecular Medicine, Pharmacology (medical), 0210 nano-technology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::85323783776f557af1a6d5fc227af5b3
https://doi.org/10.1007/s11095-021-03005-z

المؤلفون: Yuri Frosi, Shimin Jiang, Siti Radhiah Ramlan, Kelly Hew Hew, Alf Henrik Engman, Anil Pillai, Yue Xiang Cheng, Tobias Cornvik, Pär Nordlund, Megan Goh, Dilraj Lama, Chandra S Verma, Dawn Thean Thean, David P Lane, Ignacio Asial, Christopher Brown

مصطلحات موضوعية: biology, Chemistry, biology.protein, Antibody, Intracellular, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f80d30117a302deec2afff7f0e3fc6c
https://doi.org/10.21203/rs.3.rs-244469/v2

المؤلفون: Peng Zhou, Hoi Yee Chu, Becky K. C. Chan, Chaya T. L. Yuen, Feng Xu, Kaeling Tan, Gigi C. G. Choi, Zongli Zheng, Siyu Bao, Koon Ho Wong, Dawn Thean, Alan S.L. Wong

المصدر: Nature Methods. 16:722-730

مصطلحات موضوعية: Streptococcus pyogenes, Computer science, Mutagenesis (molecular biology technique), Computational biology, Protein Engineering, medicine.disease_cause, Biochemistry, Genome, Substrate Specificity, 03 medical and health sciences, Protein sequencing, Genome editing, CRISPR-Associated Protein 9, medicine, Humans, Molecular Biology, Gene, 030304 developmental biology, Gene Editing, 0303 health sciences, Mutation, Cas9, Cell Biology, Protein engineering, Mutagenesis, CRISPR-Cas Systems, Software, RNA, Guide, Kinetoplastida, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d447a8878371bd81f0bbc876e532e663
https://doi.org/10.1038/s41592-019-0473-0

المؤلفون: Brad Sherborne, Andrea M. Peier, Cesear Corona, Ahmad Sadruddin, David P. Lane, Fernando J. Ferrer-Gago, Kaustav Biswas, Dawn Thean, Arun Chandramohan, Tomi K. Sawyer, Christopher J. Brown, Nicolas Boyer, Lan Ge, Tsz Ying Yuen, Lin Yan, John R. Frost, Hung Yi Kristal Kaan, Scott D. Edmondson, Jeffrey D. Hermes, Anthony W. Partridge, Xue Er Lee, Ruchia Duggal, Chad Zimprich, Matthew B. Robers, Charles W. Johannes

المصدر: ACS chemical biology. 16(2)

مصطلحات موضوعية: 0301 basic medicine, Azides, Cell Membrane Permeability, Membrane permeability, Hydrolases, Cell, Peptide, Cell-Penetrating Peptides, Endocytosis, 01 natural sciences, Biochemistry, Peptides, Cyclic, 03 medical and health sciences, medicine, Humans, Amino Acid Sequence, Peptide sequence, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Drug discovery, General Medicine, Small molecule, 0104 chemical sciences, High-Throughput Screening Assays, Protein Transport, 030104 developmental biology, medicine.anatomical_structure, Alkynes, Biophysics, Molecular Medicine, Biological Assay, Click Chemistry, Intracellular, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607ce9191a77b1a17969c8e5ffca84ec
https://pubmed.ncbi.nlm.nih.gov/33539064

المؤلفون: Tanvi J, Desai, Bahanu, Habulihaz, Joe R, Cannon, Arun, Chandramohan, Hung Yi Kristal, Kaan, Ahmad, Sadruddin, Tsz Ying, Yuen, Charles, Johannes, Dawn, Thean, Chris J, Brown, David P, Lane, Anthony W, Partridge, Raymond, Evers, Tomi K, Sawyer, Jerome, Hochman

المصدر: Pharmaceutical research. 38(5)

مصطلحات موضوعية: Cell Membrane Permeability, Alkynes, Drug Compounding, Benzyl Compounds, Liposomes, Biotin, Humans, Biological Assay, Click Chemistry, HCT116 Cells, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a9d5959e2206b6c9ef46be0b9c76f7de
https://pubmed.ncbi.nlm.nih.gov/33821425

المؤلفون: Christopher J. Brown, Charles W. Johannes, Dawn Thean, Anthony W. Partridge, Tsz Ying Yuen, Yaw Sing Tan, Hung Yi Kristal Kaan, David P. Lane, Xue Er Lee, Jin Yong Neo, Yuezhen Xue, Chandra S. Verma, Fernando J. Ferrer Gago

المصدر: Chemical Science

مصطلحات موضوعية: 010405 organic chemistry, Chemistry, fungi, food and beverages, Stereoisomerism, Biological activity, General Chemistry, 010402 general chemistry, Metathesis, 01 natural sciences, Chemical synthesis, Combinatorial chemistry, P53 mdm2, 0104 chemical sciences, Catalysis, Adduct, Stapled peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b616ecd4eceba5debb519e7072c02b
https://doi.org/10.1039/c9sc01456j

المؤلفون: Anthony W. Partridge, David P. Lane, Tsz Ying Yuen, Dawn Thean, Bahanu Habulihaz, Ahmad Sadruddin, Tomi K. Sawyer, Arun Chandramohan, Hung Yi Kristal Kaan, Jerome Hochman, Charles Johannes, Raymond Evers, Tanvi Desai, Christopher J. Brown, Joseph R. Cannon

المصدر: Pharmaceutical Research. 38:735-736

مصطلحات موضوعية: Pharmacology, Liposome, Membrane permeability, Chemistry, Organic Chemistry, Pharmacology toxicology, Biophysics, Pharmaceutical Science, Molecular Medicine, Pharmacology (medical), Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6d3abd67728300ac8c123e86d1152d66
https://doi.org/10.1007/s11095-021-03033-9

المؤلفون: Dawn Thean, Jessica S. Ebo, Christopher J. Brown, Charles W. Johannes, Fernando J. Ferrer, T. Luxton, David P. Lane, Tsz Ying Yuen, Xue’Er Cheryl Lee

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports

مصطلحات موضوعية: Transcriptional Activation, 0301 basic medicine, Membrane permeability, Cell Survival, Pyridines, Endosome, medicine.medical_treatment, Science, Cell, Intracellular Space, Peptide, Endosomes, Article, Inhibitory Concentration 50, 03 medical and health sciences, Drug Delivery Systems, Genes, Reporter, Peptide Library, Cations, medicine, Humans, Peptide library, chemistry.chemical_classification, Multidisciplinary, Protease, Chemistry, HEK 293 cells, Proto-Oncogene Proteins c-mdm2, Lipids, Hydrocarbons, Cell biology, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, Multiprotein Complexes, Medicine, Tumor Suppressor Protein p53, Peptides, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffae1fab148babd060ee9a55d62ad4c
https://doaj.org/article/5cc897bcbc9a4ba18063d8ebc7a1fd3e

المؤلفون: Dawn Thean, Alan S.L. Wong

المصدر: Neural Regeneration Research
Neural Regeneration Research, Vol 16, Iss 12, Pp 2403-2404 (2021)

مصطلحات موضوعية: Developmental Neuroscience, Computer science, Perspective, MEDLINE, Neural differentiation, Neurology. Diseases of the nervous system, Computational biology, High order, RC346-429

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79da3d4b54d1f1956aa1a4937348605
https://doi.org/10.4103/1673-5374.313038

المؤلفون: Siyu Bao, Dawn Thean, Feng Xu, Zongli Zheng, Becky K. C. Chan, Gigi C. G. Choi, Chaya T. L. Yuen, Koon Ho Wong, Hoi Yee Chu, Kaeling Tan, Alan S.L. Wong, Peng Zhou

المصدر: Nature Methods. 16:789-789

مصطلحات موضوعية: Genome editing, Computer science, Mutagenesis (molecular biology technique), Cell Biology, Computational biology, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4ce611a11b1bedd03d879bcdca1fc0fc
https://doi.org/10.1038/s41592-019-0533-5

المؤلفون: Frosi, Yuri, Usher, Rachael, Lian, Dawn Thean Gek, Lane, David P., Brown, Christopher J.

المصدر: BMC Biology; 5/22/2019, Vol. 17 Issue 1, p1-19, 19p

مصطلحات موضوعية: PHOSPHORYLATION, GENE expression, MESSENGER RNA, PROTEIN kinases, CELL proliferation