المؤلفون: Gold, Maxwell P., Ong, Winnie, Masteller, Andrew M., Ghasemi, David R., Galindo, Julie Anne, Park, Noel R., Huynh, Nhan C., Donde, Aneesh, Pister, Veronika, Saurez, Raul A., Vladoiu, Maria C., Hwang, Grace H., Eisemann, Tanja, Donovan, Laura K., Walker, Adam D., Benetatos, Joseph, Dufour, Christelle, Garzia, Livia, Segal, Rosalind A., Wechsler-Reya, Robert J., Mesirov, Jill P., Korshunov, Andrey, Pajtler, Kristian W., Pomeroy, Scott L., Ayrault, Olivier, Davidson, Shawn M., Cotter, Jennifer A., Taylor, Michael D., Fraenkel, Ernest

المصدر: Nature Communications ; volume 15, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-023-44300-0
https://www.nature.com/articles/s41467-023-44300-0.pdf
https://www.nature.com/articles/s41467-023-44300-0

المؤلفون: Lau, Allison N., Li, Zhaoqi, Danai, Laura V., Westermark, Anna M., Darnell, Alicia M., Ferreira, Raphael, 1990, Gocheva, Vasilena, Sivanand, Sharanya, Lien, Evan C., Sapp, Kiera M., Mayers, Jared R., Biffi, Giulia, Chin, Christopher R., Davidson, Shawn M., Tuveson, David A., Jacks, Tyler, Matheson, Nicholas J., Yilmaz, Omer, Vander Heiden, Matthew G.

المصدر: eLife. 9:1-35

مصطلحات موضوعية: metabolic heterogeneity, organoid culture, PDAC, malic enzyme 1, cancer biology, pyruvate carboxylase, pancreatic cancer, mouse

وصف الملف: electronic

URL الوصول: https://research.chalmers.se/publication/518744
https://research.chalmers.se/publication/518744/file/518744_Fulltext.pdf

المؤلفون: Blanchard, Joel W, Akay, Leyla Anne, Davila-Velderrain, Jose, von Maydell, Djuna, Mathys, Hansruedi, Davidson, Shawn M, Effenberger, Audrey, Chen, Chih-Yu, Maner-Smith, Kristal, Hajjar, Ihab, Ortlund, Eric A, Bula, Michael, Agbas, Emre, Ng, Ayesha, Jiang, Xueqiao, Kahn, Martin, Blanco-Duque, Cristina, Lavoie, Nicolas, Liu, Liwang, Reyes, Ricardo, Lin, Yuan-Ta, Ko, Tak, R’Bibo, Lea, Ralvenius, William T, Bennett, David A, Cam, Hugh P, Kellis, Manolis, Tsai, Li-Huei

المساهمون: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences

المصدر: Nature

وصف الملف: application/pdf

Relation: Nature; https://hdl.handle.net/1721.1/150414; Blanchard, Joel W, Akay, Leyla Anne, Davila-Velderrain, Jose, von Maydell, Djuna, Mathys, Hansruedi et al. 2022. "APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes." Nature, 611 (7937).

الاتاحة: https://hdl.handle.net/1721.1/150414

المؤلفون: Davidson, Shawn M, Schmidt, Daniel R, Heyman, Julia E, O'Brien, James P, Liu, Amy C, Israelsen, William J, Dayton, Talya L, Sehgal, Raghav, Bronson, Roderick T, Freinkman, Elizaveta, Mak, Howard H, Fanelli, Giuseppe Nicolò, Malstrom, Scott, Bellinger, Gary, Carracedo, Arkaitz, Pandolfi, Pier Paolo, Courtney, Kevin D, Jha, Abhishek, DePinho, Ronald A, Horner, James W, Thomas, Craig J, Cantley, Lewis C, Loda, Massimo, Vander Heiden, Matthew G

المساهمون: Massachusetts Institute of Technology. Department of Biology

المصدر: AACR Journals

وصف الملف: application/pdf

Relation: Cancer Research; https://hdl.handle.net/1721.1/147020; Davidson, Shawn M, Schmidt, Daniel R, Heyman, Julia E, O'Brien, James P, Liu, Amy C et al. 2022. "Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma." Cancer Research, 82 (13).

الاتاحة: https://hdl.handle.net/1721.1/147020

المؤلفون: Ju, Linyang, Glastad, Karl M., Sheng, Lihong, Gospocic, Janko, Kingwell, Callum J., Davidson, Shawn M., Kocher, Sarah D., Bonasio, Roberto, Berger, Shelley L.

المساهمون: National Science Foundation, National Institutes of Health, National Institute of Mental Health, National Institute on Aging

المصدر: Cell ; volume 186, issue 20, page 4289-4309.e23 ; ISSN 0092-8674

الاتاحة: http://dx.doi.org/10.1016/j.cell.2023.08.002
https://api.elsevier.com/content/article/PII:S0092867423008565?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0092867423008565?httpAccept=text/plain

المؤلفون: Lu, Wenyun, Park, Noel R., TeSlaa, Tara, Jankowski, Connor S.R., Samarah, Laith, McReynolds, Melanie, Xing, Xi, Schembri, Jessica, Woolf, Morgan T., Rabinowitz, Joshua D., Davidson, Shawn M.

المساهمون: Howard Hughes Medical Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, Stand Up To Cancer, Paul G. Allen Family Foundation, Cystinosis Research Foundation, Burroughs Wellcome Fund, Calico Life Sciences Company

المصدر: Analytical Chemistry ; volume 95, issue 40, page 14879-14888 ; ISSN 0003-2700 1520-6882

الاتاحة: http://dx.doi.org/10.1021/acs.analchem.3c01875
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c01875

المؤلفون: Baytas, Ozan^1,2,3,4 (AUTHOR), Davidson, Shawn M.^5,6 (AUTHOR), Kauer, Julie A.⁷ (AUTHOR), Morrow, Eric M.^1,2 (AUTHOR) eric_morrow@brown.edu

المصدر: Molecular Brain. 11/27/2024, Vol. 17 Issue 1, p1-21. 21p.

مصطلحات موضوعية: *CHILDREN with intellectual disabilities, *GLUTAMATE dehydrogenase, *TRICARBOXYLIC acids, *SYNAPTOSOMES, *GLUTAMIC acid, *PYRAMIDAL neurons, *NEURAL transmission

المؤلفون: Quaegebeur, Annelies, Segura, Inmaculada, Schmieder, Roberta, Verdegem, Dries, Decimo, Ilaria, Bifari, Francesco, Dresselaers, Tom, Eelen, Guy, Ghosh, Debapriva, Davidson, Shawn M, Schoors, Sandra, Broekaert, Dorien, Cruys, Bert, Govaerts, Kristof, De Legher, Carla, Bouché, Ann, Schoonjans, Luc, Ramer, Matt S, Hung, Gene, Bossaert, Goele, Cleveland, Don W, Himmelreich, Uwe, Voets, Thomas, Lemmens, Robin, Bennett, C Frank, Robberecht, Wim, De Bock, Katrien, Dewerchin, Mieke, Ghesquière, Bart, Fendt, Sarah-Maria, Carmeliet, Peter

المصدر: Cell Metabolism. 23(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Stroke, Neurosciences, Nutrition, Brain Disorders, 2.1 Biological and endogenous factors, Aetiology, Underpinning research, 1.1 Normal biological development and functioning, Neurological, Animals, Brain, Brain Ischemia, Carbon, Cellular Reprogramming, Free Radical Scavengers, Gene Deletion, Hydroxylation, Hypoxia-Inducible Factor 1, alpha Subunit, Injections, Intraventricular, Mice, Knockout, Neurons, Neuroprotection, Oligonucleotides, Oxidation-Reduction, Oxygen, Pentose Phosphate Pathway, Phenotype, Procollagen-Proline Dioxygenase, Reactive Oxygen Species, Medical Biochemistry and Metabolomics, Endocrinology & Metabolism, Biochemistry and cell biology, Medical biochemistry and metabolomics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4rz5d7c1

المؤلفون: Foster, Hannah R, Ho, Thuong, Potapenko, Evgeniy, Sdao, Sophia M, Huang, Shih Ming, Lewandowski, Sophie L, VanDeusen, Halena R, Davidson, Shawn M, Cardone, Rebecca L, Prentki, Marc, Kibbey, Richard G, Merrins, Matthew J

المساهمون: National Institutes of Health, U.S. Department of Veterans Affairs, Health Resources and Services Administration, American Diabetes Association, National Insitutes of Health

المصدر: eLife ; volume 11 ; ISSN 2050-084X

الاتاحة: http://dx.doi.org/10.7554/elife.79422
https://cdn.elifesciences.org/articles/79422/elife-79422-v2.pdf
https://cdn.elifesciences.org/articles/79422/elife-79422-v2.xml
https://elifesciences.org/articles/79422

المؤلفون: Chellappa, Karthikeyani, McReynolds, Melanie R., Lu, Wenyun, Zeng, Xianfeng, Makarov, Mikhail, Hayat, Faisal, Mukherjee, Sarmistha, Bhat, Yashaswini R., Lingala, Siddharth R., Shima, Rafaella T., Descamps, Hélène C., Cox, Timothy, Ji, Lixin, Jankowski, Connor, Chu, Qingwei, Davidson, Shawn M., Thaiss, Christoph A., Migaud, Marie E., Rabinowitz, Joshua D., Baur, Joseph A.

المصدر: Cell Metabolism ; volume 34, issue 12, page 1947-1959.e5 ; ISSN 1550-4131

الاتاحة: http://dx.doi.org/10.1016/j.cmet.2022.11.004
https://api.elsevier.com/content/article/PII:S1550413122004958?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1550413122004958?httpAccept=text/plain

المؤلفون: Pillai, Ray, LeBoeuf, Sarah E., Hao, Yuan, New, Connie, Blum, Jenna L.E., Rashidfarrokhi, Ali, Huang, Shih Ming, Bahamon, Christian, Wu, Warren L., Karadal-Ferrena, Burcu, Herrera, Alberto, Ivanova, Ellie, Cross, Michael, Bossowski, Jozef P., Ding, Hongyu, Hayashi, Makiko, Rajalingam, Sahith, Karakousi, Triantafyllia, Sayin, Volkan I., 1983, Khanna, Kamal M., Wong, Kwok Kin, Wild, Robert, Tsirigos, Aristotelis, Poirier, John T., Rudin, Charles M., Davidson, Shawn M., Koralov, Sergei B., Papagiannakopoulos, Thales

المصدر: Science Advances. 10(13)

مصطلحات موضوعية: Cancer and Oncology, Cancer och onkologi

URL الوصول: https://gup.ub.gu.se/publication/341522

المؤلفون: Hamza, Bashar, Ng, Sheng Rong, Prakadan, Sanjay M., Delgado, Francisco Feijó, Chin, Christopher R., King, Emily M., Yang, Lucy F., Davidson, Shawn M., DeGouveia, Kelsey L., Cermak, Nathan, Navia, Andrew W., Winter, Peter S., Drake, Riley S., Tammela, Tuomas, Li, Carman Man-Chung, Papagiannakopoulos, Thales, Gupta, Alejandro J., Bagnall, Josephine Shaw, Knudsen, Scott M., Vander Heiden, Matthew G., Wasserman, Steven C., Jacks, Tyler, Shalek, Alex K., Manalis, Scott R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2019 Feb 01. 116(6), 2232-2236.

URL الوصول: https://www.jstor.org/stable/26663808

المؤلفون: Grassian, Alexandra R, Parker, Seth J, Davidson, Shawn M, Divakaruni, Ajit S, Green, Courtney R, Zhang, Xiamei, Slocum, Kelly L, Pu, Minying, Lin, Fallon, Vickers, Chad, Joud-Caldwell, Carol, Chung, Franklin, Yin, Hong, Handly, Erika D, Straub, Christopher, Growney, Joseph D, Heiden, Matthew G Vander, Murphy, Anne N, Pagliarini, Raymond, Metallo, Christian M

المصدر: Cancer Research. 74(12)

مصطلحات موضوعية: Cancer, Genetics, 2.1 Biological and endogenous factors, Aetiology, Animals, Antineoplastic Agents, Cell Hypoxia, Citric Acid Cycle, Enzyme Inhibitors, Glutamine, HCT116 Cells, Humans, Isocitrate Dehydrogenase, Mice, Mitochondria, Mutation, Missense, Oxidation-Reduction, Stress, Physiological, Xenograft Model Antitumor Assays, Oncology and Carcinogenesis, Oncology & Carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/69g6m263

المؤلفون: Blanchard, Joel W., Akay, Leyla Anne, Davila-Velderrain, Jose, von Maydell, Djuna, Mathys, Hansruedi, Davidson, Shawn M., Effenberger, Audrey, Chen, Chih-Yu, Maner-Smith, Kristal, Hajjar, Ihab, Ortlund, Eric A., Bula, Michael, Agbas, Emre, Ng, Ayesha, Jiang, Xueqiao, Kahn, Martin, Blanco-Duque, Cristina, Lavoie, Nicolas, Liu, Liwang, Reyes, Ricardo, Lin, Yuan-Ta, Ko, Tak, R’Bibo, Lea, Ralvenius, William T., Bennett, David A., Cam, Hugh P., Kellis, Manolis, Tsai, Li-Huei

المصدر: Nature ; ISSN 0028-0836 1476-4687

الاتاحة: https://doi.org/10.1038/s41586-024-08434-5
https://www.nature.com/articles/s41586-024-08434-5.pdf
https://www.nature.com/articles/s41586-024-08434-5

المؤلفون: Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-Kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

المصدر: Nature Chemical Biology. 8(10)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, Animals, Biopolymers, Blotting, Western, Cell Proliferation, Cell Transformation, Neoplastic, Enzyme Activators, Humans, Mice, Neoplasms, Pyruvate Kinase, Medicinal and Biomolecular Chemistry, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0s42k651

المؤلفون: Lau, Allison N, Li, Zhaoqi, Danai, Laura V, Westermark, Anna M, Darnell, Alicia M, Ferreira, Raphael, Gocheva, Vasilena, Sivanand, Sharanya, Lien, Evan C, Sapp, Kiera M, Mayers, Jared R, Biffi, Giulia, Chin, Christopher R, Davidson, Shawn M, Tuveson, David A, Jacks, Tyler, Matheson, Nicholas J, Yilmaz, Omer, Vander Heiden, Matthew G

المساهمون: Koch Institute for Integrative Cancer Research at MIT, Massachusetts Institute of Technology. Department of Biology

المصدر: eLife

وصف الملف: application/pdf

Relation: eLife; https://hdl.handle.net/1721.1/135492

الاتاحة: https://hdl.handle.net/1721.1/135492

المؤلفون: Li, Qinfeng, Li, Chao, Elnwasany, Abdallah, Sharma, Gaurav, An, Yu A., Zhang, Guangyu, Elhelaly, Waleed M., Lin, Jun, Gong, Yingchao, Chen, Guihao, Wang, Meihui, Zhao, Shangang, Dai, Chongshan, Smart, Charles D., Liu, Juan, Luo, Xiang, Deng, Yingfeng, Tan, Lin, Lv, Shuang-Jie, Davidson, Shawn M., Locasale, Jason W., Lorenzi, Philip L., Malloy, Craig R., Gillette, Thomas G., Vander Heiden, Matthew G., Scherer, Philipp E., Szweda, Luke I., Fu, Guosheng, Wang, Zhao V.

المصدر: Circulation ; volume 144, issue 9, page 712-727 ; ISSN 0009-7322 1524-4539

الاتاحة: http://dx.doi.org/10.1161/circulationaha.121.054885
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.121.054885

المؤلفون: Lau, Allison N, Li, Zhaoqi, Danai, Laura V, Westermark, Anna M, Darnell, Alicia M, Ferreira, Raphael, Gocheva, Vasilena, Sivanand, Sharanya, Lien, Evan C, Sapp, Kiera M, Mayers, Jared R, Biffi, Giulia, Chin, Christopher R, Davidson, Shawn M, Tuveson, David A, Jacks, Tyler, Matheson, Nicholas J, Yilmaz, Omer, Vander Heiden, Matthew G

مصطلحات موضوعية: PDAC, cancer biology, malic enzyme 1, metabolic heterogeneity, mouse, organoid culture, pancreatic cancer, pyruvate carboxylase, Animals, Carcinoma, Pancreatic Ductal, Female, Male, Mice, Inbred C57BL, Pancreatic Neoplasms, Tumor Microenvironment

وصف الملف: Electronic; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/311033

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/311033
https://doi.org/10.17863/CAM.58123

المؤلفون: Luengo, Alba, Abbott, Keene L., Davidson, Shawn M., Hosios, Aaron M., Chan, Sze Ham, Freinkman, Elizaveta, Lewis, Caroline A., Vander Heiden, Matthew G.

المساهمون: Massachusetts Institute of Technology. Department of Biology, Whitehead Institute for Biomedical Research, Koch Institute for Integrative Cancer Research at MIT

المصدر: Nature

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology, General Physics and Astronomy, General Chemistry

وصف الملف: application/pdf

Relation: Nature communications; https://hdl.handle.net/1721.1/124522; Luengo, Alba et al. "Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer." Nature communications 10 (2019): s41467-019-13419 © 2019 The Author(s)

الاتاحة: https://hdl.handle.net/1721.1/124522

المؤلفون: Ngo, Bryan, Kim, Eugenie, Osorio-Vasquez, Victoria, Doll, Sophia, Bustraan, Sophia, Liang, Roger J, Luengo, Alba, Davidson, Shawn M, Ali, Ahmed, Ferraro, Gino B, Fischer, Grant M, Eskandari, Roozbeh, Kang, Diane S, Ni, Jing, Plasger, Ariana, Rajasekhar, Vinagolu K, Kastenhuber, Edward R, Bacha, Sarah, Sriram, Roshan K, Stein, Benjamin D, Bakhoum, Samuel F, Snuderl, Matija, Cotzia, Paolo, Healey, John H, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Sabatini, David M, Jones, Drew R, Yu, Min, Zhao, Jean J, Jain, Rakesh K, Keshari, Kayvan R, Davies, Michael A, Vander Heiden, Matthew G, Hernando, Eva, Mann, Matthias, Cantley, Lewis C, Pacold, Michael E

المصدر: Ngo , B , Kim , E , Osorio-Vasquez , V , Doll , S , Bustraan , S , Liang , R J , Luengo , A , Davidson , S M , Ali , A , Ferraro , G B , Fischer , G M , Eskandari , R , Kang , D S , Ni , J , Plasger , A , Rajasekhar , V K , Kastenhuber , E R , Bacha , S , Sriram , R K , Stein , B D , Bakhoum , S F , Snuderl , M , Cotzia ....

الاتاحة: https://researchprofiles.ku.dk/da/publications/limited-environmental-serine-and-glycine-confer-brain-metastasis-sensitivity-to-phgdh-inhibition(d3221fcf-6320-4144-9c1f-5c5ca8c0e97d).html
https://doi.org/10.1158/2159-8290.CD-19-1228
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483776/pdf/nihms-1606588.pdf