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1Academic Journal
المؤلفون: Rachelle Driscoll, Lucas Hampton, Neeta A. Abraham, J. Douglas Larigan, Nadine F. Joseph, Juan C. Hernandez-Vega, Sarah Geisler, Fu-Chia Yang, Matthew Deninger, David T. Tran, Natasha Khatri, Bruno M. D. C. Godinho, Garth A. Kinberger, Daniel R. Montagna, Warren D. Hirst, Catherine L. Guardado, Kelly E. Glajch, H. Moore Arnold, Corrie L. Gallant-Behm, Andreas Weihofen
المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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2SCD Inhibition Protects from α-Synuclein-Induced Neurotoxicity But Is Toxic to Early Neuron Cultures
المؤلفون: Melissa Bennion, Justin W. Nicholatos, Andreas Weihofen, Joost Groot, Thomas M. Carlile, Isin Dalkilic-Liddle, Lori Hrdlicka, David T. Tran, Shekhar Dhokai, Warren D. Hirst
المصدر: eNeuro
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Parkinson's disease, cell-based assays, Cell, lipids, Neuroblastoma, synuclein, hemic and lymphatic diseases, neurotoxicity, medicine, Animals, Humans, Neurons, Gene knockdown, business.industry, General Neuroscience, Neurodegeneration, Neurotoxicity, Parkinson Disease, General Medicine, medicine.disease, Rats, SCD, medicine.anatomical_structure, Toxicity, Cancer research, Synuclein, alpha-Synuclein, Parkinson’s disease, Disorders of the Nervous System, Neuron, business, Stearoyl-CoA Desaturase, Research Article: New Research
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المؤلفون: Warren D. Hirst, Edward Guilmette, Yi Chen, Heiko Runz, Andreas Weihofen, Justin W. Nicholatos, G. Campbell Kaynor, Evgeny Shlevkov, Ellen A. Tsai, Daniel J. Apicco, YuTing Liu, Khanh-Dung H. Nguyen, Collin M. Bantle, Kelly E. Glajch, Lan T. Dang, Joost Groot, Jessica A. Hurt, Catherine L. Nezich, David T. Tran, Neeta A. Abraham
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: 0301 basic medicine, Synucleinopathies, chemistry.chemical_element, Calcium, Mitochondrion, Endoplasmic Reticulum, calcium signaling, Calcium in biology, Mice, 03 medical and health sciences, α-synuclein, 0302 clinical medicine, Calcium flux, Autophagy, Animals, genetics, Phosphorylation, Calcium signaling, Neurons, Gene knockdown, Multidisciplinary, Parkinson Disease, Biological Sciences, Mitochondria, Cell biology, Mice, Inbred C57BL, Phosphotransferases (Alcohol Group Acceptor), 030104 developmental biology, chemistry, Second messenger system, alpha-Synuclein, Parkinson’s disease, 030217 neurology & neurosurgery, Genome-Wide Association Study, Signal Transduction, Neuroscience
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4Academic Journal
المؤلفون: Wandong Zhang, Katerina V Savelieva, David T Tran, Vladimir M Pogorelov, Emily B Cullinan, Kevin B Baker, Kenneth A Platt, Sean Hu, Indrani Rajan, Nianhua Xu, Thomas H Lanthorn
المصدر: PLoS ONE, Vol 7, Iss 9, p e45500 (2012)
وصف الملف: electronic resource
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المؤلفون: Tomasz Osinski, Wladek Minor, Karolina A. Majorek, Alina Revilla, Wayne F. Anderson, David T. Tran, Misty L. Kuhn
المصدر: Biochimica et biophysica acta. Proteins and proteomics. 1865(1)
مصطلحات موضوعية: 0301 basic medicine, Staphylococcus aureus, Protein Conformation, Biophysics, Biology, Biochemistry, Article, Analytical Chemistry, Substrate Specificity, 03 medical and health sciences, Acetyltransferases, Transferase, Gnat, Amino Acid Sequence, Binding site, Molecular Biology, Genetics, chemistry.chemical_classification, 030102 biochemistry & molecular biology, Sequence Homology, Amino Acid, Clostridioides difficile, Small molecule, 030104 developmental biology, Enzyme, chemistry, Acetylation, Mutagenesis, Site-Directed, Function (biology)
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المؤلفون: Eric Buxton, Arian Oldham, Nguyen Nghi, Thomas H. Lanthorn, Zhi-Cai Shi, Catherine Bomont, David T. Tran, Qingyun Liu, Shiv Patel, Xuan Chuan Yu, Wandong Zhang
المصدر: Neuroscience Letters. 451:212-216
مصطلحات موضوعية: Neurotransmitter transporter, Drug Evaluation, Preclinical, Presynaptic Terminals, Muscarinic Antagonists, Transfection, Synaptic Transmission, Cell Line, Glycine transporter, Mice, chemistry.chemical_compound, Dopamine, Chlorocebus aethiops, medicine, Animals, Humans, Proline, Cloning, Molecular, Enzyme Inhibitors, Neurotransmitter, Dopamine transporter, Benztropine, Base Sequence, Dose-Response Relationship, Drug, Molecular Structure, biology, General Neuroscience, Brain, Transporter, Recombinant Proteins, Thiazoles, Amino Acid Transport Systems, Neutral, chemistry, Biochemistry, COS Cells, Glycine, biology.protein, Pyrazoles, Synaptosomes, medicine.drug
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7
المؤلفون: David T Tran, Mark E Hayes, Charles O Noble, Zhipeng Dai, Peter K Working, Francis C Szoka
المصدر: Blood. 128:2322-2322
مصطلحات موضوعية: 0301 basic medicine, Molar, Liposome, Chromatography, food.ingredient, Chemistry, Immunology, Iron Chelating Agents, Total body, Cell Biology, Hematology, Biochemistry, Lecithin, Deferoxamine, 03 medical and health sciences, 030104 developmental biology, food, medicine, Iron dextran, Iron Dextran Complex, medicine.drug
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المؤلفون: Nianhua Xu, Sean Hu, Kenneth A. Platt, Wandong Zhang, Emily B. Cullinan, Thomas H. Lanthorn, David T. Tran, Vladimir M. Pogorelov, Katerina V. Savelieva, Kevin B. Baker, Indrani Rajan
المصدر: PLoS ONE
PLoS ONE, Vol 7, Iss 9, p e45500 (2012)مصطلحات موضوعية: Male, Genetic Screens, Mouse, Mutant, lcsh:Medicine, Protein tyrosine phosphatase, Biochemistry, Substrate Specificity, Gene Knockout Techniques, Mice, Behavioral Neuroscience, Gene Order, Drug Discovery, Molecular Cell Biology, Membrane Receptor Signaling, Tyrosine, Phosphorylation, lcsh:Science, Mice, Knockout, Gene knockdown, Multidisciplinary, Receptor-Like Protein Tyrosine Phosphatases, Class 5, Animal Models, Recombinant Proteins, Enzymes, Phenotype, Gene Targeting, Female, Research Article, Biotechnology, Signal Transduction, Phosphatase, Physical Exertion, Mutagenesis (molecular biology technique), Biology, Motor Activity, Molecular Genetics, Model Organisms, Genetic Mutation, Genetics, Animals, Humans, Enzyme Kinetics, lcsh:R, Wild type, Proteins, Molecular biology, Transmembrane Proteins, HEK293 Cells, Mutagenesis, Mutation, Genetics of Disease, lcsh:Q, Gene Function, Animal Genetics, Neuroscience
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المؤلفون: David T Tran, Max J Petersen, Charles O Noble, Mark E Hayes, Peter Working, Francis C Szoka
المصدر: Blood. 126:2054-2054
مصطلحات موضوعية: Chromatography, biology, Immunology, Spleen, Cell Biology, Hematology, Urine, Iron sucrose, Ascorbic acid, Biochemistry, Deferoxamine, Excretion, Ferritin, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Nitric acid, medicine, biology.protein, medicine.drug
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المؤلفون: Francis C. Szoka, Charles O. Noble, David T Tran, Mark E. Hayes
المصدر: Blood. 124:4815-4815
مصطلحات موضوعية: Cholesterol, business.industry, Immunology, Spleen, Cell Biology, Hematology, Pharmacology, medicine.disease, Biochemistry, Sickle cell anemia, Bioavailability, Deferoxamine, Red blood cell, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Pharmacokinetics, medicine, Chelation therapy, business, medicine.drug