المؤلفون: Kotchaphorn Mangkalaphiban, Lianwu Fu, Ming Du, Kari Thrasher, Kim M. Keeling, David M. Bedwell, Allan Jacobson

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/0ab8ca49c18e442eb7901567b7bd6e6a

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

المصدر: PLoS ONE, Vol 18, Iss 11 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686454/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/53bd1631eb5d48589ca5f1c497aa77d3

المؤلفون: Jyoti Sharma, Ming Du, Eric Wong, Venkateshwar Mutyam, Yao Li, Jianguo Chen, Jamie Wangen, Kari Thrasher, Lianwu Fu, Ning Peng, Liping Tang, Kaimao Liu, Bini Mathew, Robert J. Bostwick, Corinne E. Augelli-Szafran, Hermann Bihler, Feng Liang, Jerome Mahiou, Josef Saltz, Andras Rab, Jeong Hong, Eric J. Sorscher, Eric M. Mendenhall, Candice J. Coppola, Kim M. Keeling, Rachel Green, Martin Mense, Mark J. Suto, Steven M. Rowe, David M. Bedwell

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1010cb2b07ac42418e6fb9795f6fb27c

المؤلفون: Andre Leier, David M. Bedwell, Ann T. Chen, George Dickson, Kim M. Keeling, Robert A. Kesterson, Bruce R. Korf, Tatiana T. Marquez Lago, Ulrich F. Müller, Linda Popplewell, Jiangbing Zhou, Deeann Wallis

المصدر: Molecular Therapy: Nucleic Acids, Vol 20, Iss , Pp 739-753 (2020)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253120301207; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/2f47ed29af8d44b7896912a5345ddaf9

المؤلفون: Kairong Li, Ashley N. Turner, Min Chen, Stephanie N. Brosius, Trenton R. Schoeb, Ludwine M. Messiaen, David M. Bedwell, Kurt R. Zinn, Corina Anastasaki, David H. Gutmann, Bruce R. Korf, Robert A. Kesterson

المصدر: Disease Models & Mechanisms, Vol 9, Iss 7, Pp 759-767 (2016)

مصطلحات موضوعية: Neurofibromatosis type 1, Patient-derived mouse models, Nonsense mutation, Missense mutation, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/9/7/759; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/0316d1cb159646e299039a5e2abac96f

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Immunology, Plant Biology, Virology, Biological Sciences not elsewhere classified, major unmet need, div >< p, affect approximately 10, promising therapeutic approach, potential therapeutic modality, prime editing machinery, cf patient homozygous, prime editing, therapeutic landscape, w1282x mutation, novel crispr, hdad ), efficiently delivered, effective treatments, dependent adenovirus, cystic fibrosis, cftr <, cf patients

Relation: https://figshare.com/articles/journal_contribution/It_includes_four_supporting_figures_figure_legends_and_a_supporting_table_/24662804

الاتاحة: https://doi.org/10.1371/journal.pone.0295009.s001
https://figshare.com/articles/journal_contribution/It_includes_four_supporting_figures_figure_legends_and_a_supporting_table_/24662804

المؤلفون: Amna Siddiqui, Halil Dundar, Jyoti Sharma, Aneta Kaczmarczyk, Josh Echols, Yanying Dai, Chuanxi Richard Sun, Ming Du, Zhong Liu, Rui Zhao, Tim Wood, Shalisa Sanders, Lynn Rasmussen, James Robert Bostwick, Corinne Augelli-Szafran, Mark Suto, Steven M. Rowe, David M. Bedwell, Kim M. Keeling

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 5; Pages: 4521

مصطلحات موضوعية: triamterene, MPS I-H, nonsense suppression, readthrough, IDUA -W402X

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms24054521

الاتاحة: https://doi.org/10.3390/ijms24054521

المؤلفون: Jianguo Chen, Kari Thrasher, Lianwu Fu, Wei Wang, Soheil Aghamohammadzadeh, Hui Wen, Liping Tang, Kim M. Keeling, Emily Falk Libby, David M. Bedwell, Steven M. Rowe

المصدر: American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L756-L770

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Physiology, Physiology (medical), Cell Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::be29a9aa69f196a7f68d2016b2741c5c
https://doi.org/10.1152/ajplung.00038.2023

المؤلفون: Kim M Keeling, David M Bedwell

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: aminoglycoside, ribosome, readthrough, ribosome profiling, translation, Medicine, Science, Biology (General), QH301-705.5

Relation: https://elifesciences.org/articles/55960; https://doaj.org/toc/2050-084X; e55960; https://doaj.org/article/6e0a320abd9c47f6a15c6a74c2eddd26

الاتاحة: https://doi.org/10.7554/eLife.55960
https://doaj.org/article/6e0a320abd9c47f6a15c6a74c2eddd26

المؤلفون: Michael Daniel, David M. Bedwell, Ashlee Long, Robert A. Kesterson, Hui Liu, Deeann Wallis, Jian Liu, Bruce R. Korf

المصدر: Human Mutation. 43:30-41

مصطلحات موضوعية: Genetics, congenital, hereditary, and neonatal diseases and abnormalities, Neurofibromatosis 1, Neurofibromin 1, Low protein, biology, GTPase, Phenotype, Complementary DNA, Genes, Neurofibromatosis 1, biology.protein, Humans, Missense mutation, splice, Precision Medicine, Gene, Genetics (clinical), Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b386bad778ab20bba50baf65a74c2c
https://doi.org/10.1002/humu.24290

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Immunology, Plant Biology, Virology, Biological Sciences not elsewhere classified, major unmet need, div >< p, affect approximately 10, promising therapeutic approach, potential therapeutic modality, prime editing machinery, cf patient homozygous, prime editing, therapeutic landscape, w1282x mutation, novel crispr, hdad ), efficiently delivered, effective treatments, dependent adenovirus, cystic fibrosis, cftr <, cf patients

Relation: https://figshare.com/articles/media/W1282X_organoid_FIS_assay_/24662807

الاتاحة: https://doi.org/10.1371/journal.pone.0295009.s002
https://figshare.com/articles/media/W1282X_organoid_FIS_assay_/24662807

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Immunology, Plant Biology, Virology, Biological Sciences not elsewhere classified, major unmet need, div >< p, affect approximately 10, promising therapeutic approach, potential therapeutic modality, prime editing machinery, cf patient homozygous, prime editing, therapeutic landscape, w1282x mutation, novel crispr, hdad ), efficiently delivered, effective treatments, dependent adenovirus, cystic fibrosis, cftr <, cf patients

Relation: https://figshare.com/articles/media/PE_organoid_FIS_assay_/24662810

الاتاحة: https://doi.org/10.1371/journal.pone.0295009.s003
https://figshare.com/articles/media/PE_organoid_FIS_assay_/24662810

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Immunology, Plant Biology, Virology, Biological Sciences not elsewhere classified, major unmet need, div >< p, affect approximately 10, promising therapeutic approach, potential therapeutic modality, prime editing machinery, cf patient homozygous, prime editing, therapeutic landscape, w1282x mutation, novel crispr, hdad ), efficiently delivered, effective treatments, dependent adenovirus, cystic fibrosis, cftr <, cf patients

Relation: https://figshare.com/articles/figure/Prime_editing_restored_CFTR_function_in_PE-iPSC-derived_lung_tissues_/24662822

الاتاحة: https://doi.org/10.1371/journal.pone.0295009.g003
https://figshare.com/articles/figure/Prime_editing_restored_CFTR_function_in_PE-iPSC-derived_lung_tissues_/24662822

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Immunology, Plant Biology, Virology, Biological Sciences not elsewhere classified, major unmet need, div >< p, affect approximately 10, promising therapeutic approach, potential therapeutic modality, prime editing machinery, cf patient homozygous, prime editing, therapeutic landscape, w1282x mutation, novel crispr, hdad ), efficiently delivered, effective treatments, dependent adenovirus, cystic fibrosis, cftr <, cf patients

Relation: https://figshare.com/articles/figure/_i_CFTR_i_W1282X_mutation_is_amenable_to_prime_editing-mediated_gene_correction_/24662813

الاتاحة: https://doi.org/10.1371/journal.pone.0295009.g001
https://figshare.com/articles/figure/_i_CFTR_i_W1282X_mutation_is_amenable_to_prime_editing-mediated_gene_correction_/24662813

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Immunology, Plant Biology, Virology, Biological Sciences not elsewhere classified, major unmet need, div >< p, affect approximately 10, promising therapeutic approach, potential therapeutic modality, prime editing machinery, cf patient homozygous, prime editing, therapeutic landscape, w1282x mutation, novel crispr, hdad ), efficiently delivered, effective treatments, dependent adenovirus, cystic fibrosis, cftr <, cf patients

Relation: https://figshare.com/articles/figure/Differentiation_of_iPSCs_to_airway_epithelial_cells_and_lung_organoids_/24662819

الاتاحة: https://doi.org/10.1371/journal.pone.0295009.g002
https://figshare.com/articles/figure/Differentiation_of_iPSCs_to_airway_epithelial_cells_and_lung_organoids_/24662819

المؤلفون: Chao Li, Zhong Liu, Justin Anderson, Zhongyu Liu, Liping Tang, Yao Li, Ning Peng, Jianguo Chen, Xueming Liu, Lianwu Fu, Tim M. Townes, Steven M. Rowe, David M. Bedwell, Jennifer Guimbellot, Rui Zhao

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Immunology, Plant Biology, Virology, Biological Sciences not elsewhere classified, major unmet need, div >< p, affect approximately 10, promising therapeutic approach, potential therapeutic modality, prime editing machinery, cf patient homozygous, prime editing, therapeutic landscape, w1282x mutation, novel crispr, hdad ), efficiently delivered, effective treatments, dependent adenovirus, cystic fibrosis, cftr <, cf patients

Relation: https://figshare.com/articles/figure/Prime_editing_corrects_the_W1282X_mutation_in_differentiated_airway_epithelial_cells_/24662828

الاتاحة: https://doi.org/10.1371/journal.pone.0295009.g004
https://figshare.com/articles/figure/Prime_editing_corrects_the_W1282X_mutation_in_differentiated_airway_epithelial_cells_/24662828

المؤلفون: Ming Du, Ning Peng, Jamie R Wangen, Jianguo Chen, Rachel Green, Venkateshwar Mutyam, Yao Li, Kari Thrasher, Corinne E. Augelli-Szafran, Jerome Mahiou, Feng Liang, Jyoti Sharma, Lianwu Fu, Candice J. Coppola, Kim M. Keeling, Martin Mense, Eric M. Mendenhall, Jeong S. Hong, Hermann Bihler, Liping Tang, Robert Bostwick, Eric J. Sorscher, Bini Mathew, Josef Saltz, Steven M. Rowe, Andras Rab, Kaimao Liu, David M. Bedwell, Mark J. Suto, Eric Wong

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Termination factor, viruses, Science, Nonsense mutation, Nonsense-mediated decay, General Physics and Astronomy, Cystic Fibrosis Transmembrane Conductance Regulator, RNA decay, General Biochemistry, Genetics and Molecular Biology, Article, Cystic fibrosis, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, RNA interference, Genes, Reporter, Humans, Multidisciplinary, Molecular medicine, Chemistry, Translational readthrough, HEK 293 cells, fungi, Translation (biology), Epithelial Cells, General Chemistry, Peptide Chain Termination, Translational, Stop codon, Cell biology, Nonsense Mediated mRNA Decay, 030104 developmental biology, Aminoglycosides, HEK293 Cells, Codon, Nonsense, Microsomes, Liver, RNA, RNA Interference, Gentamicins, Ribosomes, 030217 neurology & neurosurgery, Peptide Termination Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f418523dd1d2b9e08e9eb070c8ea0a14
https://doaj.org/article/1010cb2b07ac42418e6fb9795f6fb27c

المؤلفون: Ulrich Müller, Linda Popplewell, Tatiana T. Marquez Lago, Deeann Wallis, Ann T. Chen, Bruce R. Korf, André Leier, Robert A. Kesterson, David M. Bedwell, Kim M. Keeling, George Dickson, Jiangbing Zhou

المصدر: Molecular Therapy: Nucleic Acids, Vol 20, Iss, Pp 739-753 (2020)
Molecular Therapy. Nucleic Acids

مصطلحات موضوعية: 0301 basic medicine, Bioinformatics, medicine.disease_cause, Article, Viral vector, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, CRISPR, Loss function, Neurofibromatosis type I, Mutation, biology, business.industry, lcsh:RM1-950, Genetic disorder, medicine.disease, Neurofibromin 1, Exon skipping, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67bd4f05e6ebccac008c792e6306d9b
http://www.sciencedirect.com/science/article/pii/S2162253120301207

المؤلفون: Kim M. Keeling, Andre Leier, David M. Bedwell, Ann T. Chen, Robert A. Kesterson, Tatiana T. Marquez Lago, Ulrich F. Müller, Jiangbing Zhou, Linda Popplewell, Deeann Wallis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c4a7366577b193977f85c5004e8865b4
https://doi.org/10.1016/b978-0-12-824010-6.00009-5

المؤلفون: Katherine L Tuggle, Susan E Birket, Xiaoxia Cui, Jeong Hong, Joe Warren, Lara Reid, Andre Chambers, Diana Ji, Kevin Gamber, Kengyeh K Chu, Guillermo Tearney, Li Ping Tang, James A Fortenberry, Ming Du, Joan M Cadillac, David M Bedwell, Steven M Rowe, Eric J Sorscher, Michelle V Fanucchi

المصدر: PLoS ONE, Vol 9, Iss 3, p e91253 (2014)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3946746?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/cda01f9339b140bb92a4e09c988812c8

الاتاحة: https://doi.org/10.1371/journal.pone.0091253
https://doaj.org/article/cda01f9339b140bb92a4e09c988812c8