المؤلفون: Michael J. Rudolph, Simon A. Davis, H. M. Emranul Haque, David D. Weis, David J. Vance, Carol Lyn Piazza, Monir Ejemel, Lisa Cavacini, Yang Wang, M. Lamine Mbow, Robert D. Gilmore, Nicholas J. Mantis

المصدر: mBio, Vol 14, Iss 2 (2023)

مصطلحات موضوعية: Borreliella burgdorferi, Lyme disease, X-ray crystallography, monoclonal antibodies, spirochetes, vaccines, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/c08808c46b244cddb14dfe929eef3a85

المؤلفون: Siva Krishna Angalakurthi, David J. Vance, Yinghui Rong, Chi My Thi Nguyen, Michael J. Rudolph, David Volkin, C. Russell Middaugh, David D. Weis, Nicholas J. Mantis

المصدر: Antibodies, Vol 7, Iss 4, p 45 (2018)

مصطلحات موضوعية: toxin, antibody, camelid, vaccine, biodefense, hydrogen exchange-mass spectrometry, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4468/7/4/45; https://doaj.org/toc/2073-4468

URL الوصول: https://doaj.org/article/08b529d18940415d831f6223da371ea8

المؤلفون: Tyler S. Hageman (6823580), Michael S. Wrigley (4255177), David D. Weis (1412326)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Neuroscience, Physiology, Pharmacology, Immunology, Developmental Biology, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Differential Hydrogen Exchange-Mass., Equivalence acceptance criteria, HX-MS measurements, MDTE, equivalent, equivalence testing method, Higher-Order Protein Structures, Remicade reference product, Hydrogen exchange-mass spectrometry, TOST-MDTE, NIST mAb reference, HX-MS data, TOST, protein, Statistical Equivalence Testing

Relation: https://figshare.com/articles/journal_contribution/Statistical_Equivalence_Testing_of_Higher-Order_Protein_Structures_with_Differential_Hydrogen_Exchange-Mass_Spectrometry_HX-MS_/14510820

الاتاحة: https://doi.org/10.1021/acs.analchem.0c05279.s001

المؤلفون: H. M. Emranul Haque, Monir Ejemel, David J. Vance, Graham Willsey, Michael J. Rudolph, Lisa A. Cavacini, Yang Wang, Nicholas J. Mantis, David D. Weis

المصدر: ACS Infectious Diseases. 8:2515-2528

مصطلحات موضوعية: Infectious Diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679f608a3f20256d6f13d185b32211fa
https://doi.org/10.1021/acsinfecdis.2c00346

المؤلفون: H. M. Emranul Haque, Nicholas J. Mantis, David D. Weis

المصدر: Journal of the American Society for Mass Spectrometry. 34(1)

مصطلحات موضوعية: Epitopes, Structural Biology, Antigens, Spectroscopy, Epitope Mapping, Mass Spectrometry, Hydrogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2571a3db56ffecb947fe86541b1d9b7
https://pubmed.ncbi.nlm.nih.gov/36449379

المؤلفون: Michael J. Rudolph, Simon A. Davis, H M Emranul Haque, David D. Weis, David J Vance, Carol Lyn Piazza, Monir Ejemel, Lisa Cavacini, Yang Wang, M. Lamine Mbow, Robert D. Gilmore, Nicholas J Mantis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7afeff799c470b8a3eae5dfe9a85cb20
https://doi.org/10.1101/2022.11.28.518297

المؤلفون: Juan Pablo Rincon Pabon, Clint Vorauer, Michael S. Wrigley, David D. Weis, Charlie C. Mundorff, Michael J. Watson, Miklos Guttman

المصدر: Journal of the American Society for Mass Spectrometry. 32:2386-2390

مصطلحات موضوعية: Protein Conformation, Swine, medicine.medical_treatment, Hydrogen Deuterium Exchange-Mass Spectrometry, Peptide, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Column (database), Pepsin, Structural Biology, medicine, Animals, Spectroscopy, chemistry.chemical_classification, Protease, Chromatography, biology, Chemistry, 010401 analytical chemistry, Proteins, Reproducibility of Results, Enzymes, Immobilized, Pepsin A, Peptide Fragments, 0104 chemical sciences, Rapid assessment, biology.protein, Hydrogen–deuterium exchange, Digestion, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8f2be57c27ab777cb70adfa2870237
https://doi.org/10.1021/jasms.1c00080

المؤلفون: Chen Yan, Michael T. Kim, Sharmila Rajan, Vittal Shivva, Martin Lechmann, Aron Lee, David D. Weis

المصدر: Journal of Pharmaceutical Sciences. 110:1989-1996

مصطلحات موضوعية: medicine.drug_class, Kinetics, Pharmaceutical Science, 02 engineering and technology, Monoclonal antibody, 030226 pharmacology & pharmacy, Mass Spectrometry, law.invention, 03 medical and health sciences, 0302 clinical medicine, Biotransformation, In vivo, law, medicine, Animals, Sulfhydryl Compounds, Rats, Wistar, biology, Chemistry, Free thiol, 021001 nanoscience & nanotechnology, Rats, Biochemistry, Immunoglobulin G, Recombinant DNA, biology.protein, Antibody, 0210 nano-technology, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c19ae443487b067bad5ee8fa3198a1
https://doi.org/10.1016/j.xphs.2021.02.009

المؤلفون: Michael S. Wrigley, Tyler S. Hageman, David D. Weis

المصدر: Analytical Chemistry. 93:6980-6988

مصطلحات موضوعية: Chemistry, 010401 analytical chemistry, Univariate, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Infliximab, Maltose-Binding Proteins, Mass Spectrometry, 0104 chemical sciences, Analytical Chemistry, Equivalent, Similarity (network science), Acceptance testing, Resampling, NIST, Biological system, Biosimilar Pharmaceuticals, Equivalence (measure theory), Hydrogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9272f83ac48b1dae8fef29c101dcd2a0
https://doi.org/10.1021/acs.analchem.0c05279

المؤلفون: J. Christopher Love, John M. Hickey, David D. Weis, Kerry R. Love, Joseph R. Brady, Sanjeev Agarwal, Nishant Sawant, David B. Volkin, Mary Kate Tracey, Kawaljit Kaur, Jian Xiong, David A. Holland, Sangeeta B. Joshi, Neil C. Dalvie, Tarit Mukhopadhyay

المصدر: Journal of Pharmaceutical Sciences

مصطلحات موضوعية: Rotavirus, Pharmaceutical Biotechnology, Protein subunit, Epitope mapping, Protein antigen, Pharmaceutical Science, 02 engineering and technology, 030226 pharmacology & pharmacy, law.invention, Protein–protein interaction, 03 medical and health sciences, Residue (chemistry), 0302 clinical medicine, Antigen, law, HX-MS, Multi-dose, Antigens, Viral, Chemistry, Thimerosal, Preservatives, Pharmaceutical, 021001 nanoscience & nanotechnology, Formulation, Vaccines, Subunit, Biophysics, Recombinant DNA, 0210 nano-technology, Stability, Vaccine, Preservative, Research Article, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e2ff4fa158cb685c1de46cd1f1d053
https://doi.org/10.1016/j.xphs.2020.11.033

المؤلفون: Chamalee L. D Gamage, David D. Weis, Benjamin T. Walters

المصدر: Journal of pharmaceutical sciences. 111(8)

مصطلحات موضوعية: Antineoplastic Agents, Immunological, Pharmaceutical Science, Antibodies, Monoclonal, Water, Adsorption, Mass Spectrometry, Hydrogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4873f875f931644a7abab07e1a4524
https://pubmed.ncbi.nlm.nih.gov/35533783

المؤلفون: Tyler S. Hageman, Chamalee L.D. Gamage, David D. Weis

المصدر: Journal of Pharmaceutical Sciences. 108:1964-1972

مصطلحات موضوعية: Chemistry, Pharmaceutical, Drug Storage, Kinetics, Pharmaceutical Science, Hydrogen Deuterium Exchange-Mass Spectrometry, Peptide, 02 engineering and technology, Mass spectrometry, 030226 pharmacology & pharmacy, Maltose-Binding Proteins, 03 medical and health sciences, 0302 clinical medicine, Drug Stability, Asparagine, Deamidation, chemistry.chemical_classification, Hydrogen exchange, Protein Stability, Reproducibility of Results, 021001 nanoscience & nanotechnology, Amides, Models, Chemical, chemistry, Biophysics, Feasibility Studies, Hydrogen–deuterium exchange, Trypsin Digestion, 0210 nano-technology, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40ecc120402d4513bf84bd116b0d7e1
https://doi.org/10.1016/j.xphs.2019.01.019

المؤلفون: Tyler S. Hageman, David D. Weis

المصدر: Analytical Chemistry. 91:8017-8024

مصطلحات موضوعية: Models, Molecular, Detection limit, chemistry.chemical_classification, Circular dichroism, biology, Protein Conformation, Escherichia coli Proteins, Size-exclusion chromatography, Deuterium Exchange Measurement, Peptide, Mass spectrometry, Maltose-Binding Proteins, Mass Spectrometry, Analytical Chemistry, Maltose-binding protein, Protein structure, Differential scanning calorimetry, chemistry, Limit of Detection, Escherichia coli, biology.protein, Point Mutation, Biological system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fab16bd44730e0a09ab54fcfc254a7
https://doi.org/10.1021/acs.analchem.9b01326

المؤلفون: Sangeeta B. Joshi, David B. Volkin, Nishant Sawant, David D. Weis

المصدر: Journal of pharmaceutical sciences. 111(4)

مصطلحات موضوعية: Chlorobutanol, Preservative, Ethanol, Stereochemistry, Thimerosal, Preservatives, Pharmaceutical, Pharmaceutical Science, Parabens, Epitope, Paraben, law.invention, chemistry.chemical_compound, chemistry, Adjuvants, Immunologic, Benzyl alcohol, law, Recombinant DNA, Antigens, Adjuvants, Pharmaceutic, Aluminum

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa6c207cb51c32c34058175c008aad6
https://pubmed.ncbi.nlm.nih.gov/34758340

المؤلفون: David D. Weis

المصدر: Journal of the American Society for Mass Spectrometry. 32(7)

مصطلحات موضوعية: Propagation of uncertainty, Work (thermodynamics), Hydrogen, Chemistry, 010401 analytical chemistry, Thermodynamics, chemistry.chemical_element, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Standard deviation, 0104 chemical sciences, Experimental uncertainty analysis, Deuterium, Structural Biology, Range (statistics), Spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f4231c1ee2d72cc1d0ebd05ee3abc6
https://pubmed.ncbi.nlm.nih.gov/33764776

المؤلفون: David D. Weis, Douglas D. Richardson, Juan Pablo Rincon Pabon, Brent A. Kochert, Yan-Hui Liu

المصدر: Journal of pharmaceutical sciences. 110(6)

مصطلحات موضوعية: medicine.drug_class, Allosteric regulation, Pharmaceutical Science, 02 engineering and technology, Plasma protein binding, Matrix (biology), Monoclonal antibody, 030226 pharmacology & pharmacy, Mass Spectrometry, 03 medical and health sciences, 0302 clinical medicine, Affinity chromatography, medicine, Staphylococcal Protein A, Proa, biology, Chemistry, Antibodies, Monoclonal, 021001 nanoscience & nanotechnology, biology.organism_classification, Biochemistry, Immunoglobulin G, biology.protein, Hydrogen–deuterium exchange, 0210 nano-technology, Protein A, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a5616c289d1384f000322a486bdecb
https://pubmed.ncbi.nlm.nih.gov/33640336

المؤلفون: Brittney J. Mills, Samantha E. Pace, David D. Weis, Reza Esfandiary, David B. Volkin, C. Russell Middaugh, Ronald T. Toth, Sangeeta B. Joshi

المصدر: Journal of Pharmaceutical Sciences. 107:1009-1019

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, medicine.drug_class, Chemistry, Pharmaceutical, Size-exclusion chromatography, Pharmaceutical Science, Excipient, Peptide, Monoclonal antibody, Mass spectrometry, 030226 pharmacology & pharmacy, Mass Spectrometry, Excipients, 03 medical and health sciences, 0302 clinical medicine, Differential scanning calorimetry, medicine, Molecule, chemistry.chemical_classification, Calorimetry, Differential Scanning, Protein Stability, Chemistry, Antibodies, Monoclonal, Deuterium Exchange Measurement, 030104 developmental biology, Immunoglobulin G, Forced degradation, Chromatography, Gel, Biophysics, Hydrogen, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951be3f3caf27c3149f06ce21d414bd6
https://doi.org/10.1016/j.xphs.2017.12.009

المؤلفون: David D. Weis (1412326)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Cancer, Plant Biology, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, uncertainty result, deuterium recovery, dynamic, Quantitative differences, Hydrogen Exchange-Mass Spectrometri., HX time course, measures range, ligand binding, protein structure, hydrogen exchange, higher-order structure, HX measurements, mass differences, HX-MS, higher-order protein structure, uncertainty propagation

Relation: https://figshare.com/articles/dataset/Recommendations_for_the_Propagation_of_Uncertainty_in_Hydrogen_Exchange-Mass_Spectrometric_Measurements/14308740

الاتاحة: https://doi.org/10.1021/jasms.0c00475.s001

المؤلفون: David D. Weis, Brittney J. Mills, Steven M. Bishop, Sangeeta B. Joshi, C. Russell Middaugh, David B. Volkin, Ronald T. Toth, Reza Esfandiary

المصدر: Analytical Chemistry. 89:8931-8941

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Thiocyanate, Hydrogen, 010401 analytical chemistry, Chemical exchange, Inorganic chemistry, Analytical chemistry, chemistry.chemical_element, Peptide, Mass spectrometry, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Buffering agent, Ionic strength, Guanidine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93bc284b6ff0a2c32fa19b263d9ef2a
https://doi.org/10.1021/acs.analchem.7b01396

المؤلفون: Siva Krishna Angalakurthi, Nicholas J. Mantis, Ronald T. Toth, Andrea Bazzoli, C. Russell Middaugh, John Karanicolas, David B. Volkin, David D. Weis, Michael J. Rudolph, Yinghui Rong, David J. Vance

المصدر: Proteins: Structure, Function, and Bioinformatics

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein subunit, Mutant, Ricin, Protein Engineering, Biochemistry, Article, Epitope, 03 medical and health sciences, chemistry.chemical_compound, Structural Biology, Animals, Amino Acid Sequence, Homology modeling, Molecular Biology, Peptide sequence, Camelidae, biology, Single-Domain Antibodies, Antibodies, Neutralizing, Molecular biology, 030104 developmental biology, Epitope mapping, chemistry, biology.protein, Antibody, Sequence Alignment, Epitope Mapping, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1627644f7f8cf4ba35fbe6f66bd8b9
https://doi.org/10.1002/prot.25353