المؤلفون: Molecular Pain, Lana Klionsky, Rami Tamir, Baoxi Gao, Weiya Wang, David C Immke, Nobuko Nishimura, Narender R Gavva

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/35/38/Mol_Pain_2007_Dec_17_3_39.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.282.4811

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.282.4811

المؤلفون: Molecular Pain, Derek C Molliver, David C Immke, Leonardo Fierro, Michel Paré, Frank L Rice, Edwin W Mccleskey

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/32/93/Mol_Pain_2005_Nov_23_1_35.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.276.339

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.276.339

المؤلفون: Dah-Ren Hwang, Geraldine Hill Della Puppa, Jamie Wong, Essa Hu, Thomas Nixey, Silke Miller, Hang Chen, Jessica Able, Dianna Lester-Zeiner, James J. S. Treanor, Robert Cho, Santosh Talreja, Roxanne Kunz, Jianxia Shi, Ji Ma, David C. Immke, Jennifer R. Allen, Christopher Biorn, Amy Porter, Klaus Michelsen, Shannon Rumfelt, Stephen Hitchcock

المصدر: Journal of Medicinal Chemistry. 55:4776-4787

مصطلحات موضوعية: Male, Phosphodiesterase Inhibitors, Aminopyridines, Striatum, In Vitro Techniques, Tritium, Permeability, Cell Line, Rats, Sprague-Dawley, Dogs, Tandem Mass Spectrometry, In vivo, TRACER, Drug Discovery, Animals, Humans, Tissue Distribution, ATP Binding Cassette Transporter, Subfamily B, Member 1, Radionuclide Imaging, Phosphoric Diester Hydrolases, Drug discovery, Chemistry, Brain, Phosphodiesterase, Stereoisomerism, Surface Plasmon Resonance, Molecular biology, Small molecule, Rats, Pyridazines, Rapid identification, Quinolines, Pyrazoles, Molecular Medicine, PDE10A, Radiopharmaceuticals, Chromatography, Liquid, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626c862c5f50bd2845e3c603ba24a357
https://doi.org/10.1021/jm3002372

المؤلفون: David C. Immke, Mark H. Norman, Vu Van Ma, Ruoyuan Yin, Elizabeth M. Doherty, Vijay Keshav Gore, Joe Ligutti

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:3573-3578

مصطلحات موضوعية: Membrane bound, Migraine Disorders, Clinical Biochemistry, Regulator, Pharmaceutical Science, CHO Cells, Pharmacology, Models, Biological, Trigeminal Nuclei, Biochemistry, Structure-Activity Relationship, Cricetulus, Cricetinae, Drug Discovery, Animals, Humans, Structure–activity relationship, Premovement neuronal activity, Large-Conductance Calcium-Activated Potassium Channel alpha Subunits, Molecular Biology, Neurons, biology, Chemistry, Organic Chemistry, biology.organism_classification, Calcium-activated potassium channel, Potassium channel, Electrophysiological Phenomena, Rats, Electrophysiology, Quinolines, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ec2aa172b1a3114de4128928e20321
https://doi.org/10.1016/j.bmcl.2010.04.125

المؤلفون: Weiya Wang, Lana Klionsky, BaoXi Gao, Narender R. Gavva, Rami Tamir, David C. Immke, Nobuko Nishimura

المصدر: Molecular Pain, Vol 3, Iss 1, p 39 (2007)
Molecular Pain

مصطلحات موضوعية: Calcium Isotopes, Patch-Clamp Techniques, CHO Cells, Pharmacology, Transfection, Membrane Potentials, Inhibitory Concentration 50, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Transient receptor potential channel, Cricetulus, Transient Receptor Potential Channels, Species Specificity, Isothiocyanates, Cricetinae, lcsh:Pathology, medicine, Animals, Humans, Drug Interactions, Patch clamp, Neurogenic inflammation, Dose-Response Relationship, Drug, Research, Chinese hamster ovary cell, food and beverages, Rats, Cold Temperature, Anesthesiology and Pain Medicine, chemistry, Biochemistry, Capsaicin, Cell culture, Benzamides, Hyperalgesia, Knockout mouse, Molecular Medicine, Calcium, medicine.symptom, psychological phenomena and processes, lcsh:RB1-214

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866c0e2d52735a4a1dac7c1724e7c0bd
https://doi.org/10.1186/1744-8069-3-39

المؤلفون: David C. Immke, Brian Smith, Jianhua Zhang, Hong Sun, Sonya G. Lehto, Licheng Shi, Kenneth D. Wild, Cen Xu, Dawn Zhu

المصدر: The Journal of pharmacology and experimental therapeutics. 356(1)

مصطلحات موضوعية: medicine.medical_specialty, Calcitonin Gene-Related Peptide, Migraine Disorders, Calcitonin gene-related peptide, Pharmacology, Antibodies, Monoclonal, Humanized, Binding, Competitive, chemistry.chemical_compound, Mice, Calcitonin gene-related peptide receptor antagonist, Dogs, In vivo, Calcitonin Gene-Related Peptide Receptor Antagonists, Internal medicine, medicine, Cyclic AMP, Animals, Humans, Receptor, Skin, integumentary system, Dose-Response Relationship, Drug, Antibodies, Monoclonal, Receptors, Calcitonin, Rats, Adrenomedullin, Macaca fascicularis, Endocrinology, chemistry, Capsaicin, Calcitonin, Regional Blood Flow, Molecular Medicine, Rabbits, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340896e6a0d2bcae597f2094e3303776
https://pubmed.ncbi.nlm.nih.gov/26559125

المؤلفون: Narender R. Gavva, David C. Immke

المصدر: Seminars in Cell & Developmental Biology. 17:582-591

مصطلحات موضوعية: TRPV1, Pain, TRPV Cation Channels, Pharmacology, Biology, Models, Biological, Mice, chemistry.chemical_compound, medicine, Animals, Thermosensing, Receptor, Sensitization, Mice, Knockout, Neurons, Molecular Structure, musculoskeletal, neural, and ocular physiology, Chronic pain, Nociceptors, Cell Biology, medicine.disease, Nociception, medicine.anatomical_structure, nervous system, chemistry, Capsaicin, Drug Design, Nociceptor, lipids (amino acids, peptides, and proteins), Transduction (physiology), psychological phenomena and processes, Signal Transduction, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56f72b433ba5a43e0b5803c69dccd6a
https://doi.org/10.1016/j.semcdb.2006.09.004

المؤلفون: Narender R. Gavva, James J. S. Treanor, Todd W. Vanderah, Yusheng Qu, Jean Claude Louis, Tie J. Zhang, Frank Porreca, Kenneth D. Wild, Elizabeth M. Doherty, Rami Tamir, David C. Immke, Anthony W. Bannon, Mark H. Norman, Lana Klionsky, Judy Wang, Dawn Zhu

المصدر: Journal of Pharmacology and Experimental Therapeutics. 313:474-484

مصطلحات موضوعية: Hot Temperature, Patch-Clamp Techniques, Calcitonin Gene-Related Peptide, Receptors, Drug, Freund's Adjuvant, TRPV1, CHO Cells, Motor Activity, Pharmacology, Transfection, Rats, Sprague-Dawley, chemistry.chemical_compound, Dorsal root ganglion, In vivo, Cricetinae, Ganglia, Spinal, medicine, Animals, Humans, Receptor, Cells, Cultured, Pain Measurement, Inflammation, Neurons, Acrylamides, Behavior, Animal, musculoskeletal, neural, and ocular physiology, Antagonist, Bridged Bicyclo Compounds, Heterocyclic, Rats, medicine.anatomical_structure, nervous system, chemistry, Hyperalgesia, Capsaicin, Competitive antagonist, Molecular Medicine, lipids (amino acids, peptides, and proteins), Protons, medicine.symptom, Psychomotor Performance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa997157a9236df5940afebfb38eb8c
https://doi.org/10.1124/jpet.104.079855

المؤلفون: Maosheng Zhang, David C. Immke, Chi-Ming Li, Ruoyuan Yin, Mark Chhoa, Sonya G. Lehto, Dong Liu, Bryan D. Moyer, Yi Luo

المصدر: The International journal of neuroscience. 126(2)

مصطلحات موضوعية: 0301 basic medicine, Male, Patch-Clamp Techniques, Tetrodotoxin, Voltage-Gated Sodium Channels, Biophysical Phenomena, Functional Laterality, Membrane Potentials, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Dorsal root ganglion, Peripheral Nerve Injuries, Ganglia, Spinal, medicine, Animals, Patch clamp, RNA, Messenger, Membrane potential, Neurons, Chemistry, musculoskeletal, neural, and ocular physiology, General Neuroscience, Sodium channel, General Medicine, Electric Stimulation, Rats, Electrophysiology, 030104 developmental biology, medicine.anatomical_structure, nervous system, Gene Expression Regulation, Hyperalgesia, Neuropathic pain, medicine.symptom, Neuroscience, 030217 neurology & neurosurgery, Sodium Channel Blockers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bdef1343a7ae6ad24c48e7f6ca7aa3
https://pubmed.ncbi.nlm.nih.gov/25562420

المؤلفون: Hu Ye, Tim Kazules, Ji Ma, Dianna Lester-Zeiner, Essa Hu, Santosh Talreja, Carl Davis, Charlie Glaus, Oliver R. Thiel, Ning Chen, Geraldine Hill Della Puppa, James J. S. Treanor, Shannon Rumfelt, Hui Hannah Dou, Roxanne Kunz, David C. Immke, Jessica Able, Jennifer R. Allen, Silke Miller, Xiaoning Zhao, Hang Chen, Jianxia Shi, Jamie Wong, Toni Williamson, Christopher Biorn, Amy Porter, Klaus Michelsen, Ada Chen

المصدر: The Journal of pharmacology and experimental therapeutics. 352(2)

مصطلحات موضوعية: Male, Fluorine Radioisotopes, Phosphodiesterase Inhibitors, Pharmacology, Mass Spectrometry, Rats, Sprague-Dawley, Radioligand Assay, Species Specificity, medicine, Distribution (pharmacology), Animals, Humans, Tissue Distribution, medicine.diagnostic_test, Molecular Structure, Chemistry, Drug discovery, Phosphoric Diester Hydrolases, Antagonist, Phosphodiesterase, Brain, Stereoisomerism, Surface Plasmon Resonance, Small molecule, Drug development, Positron emission tomography, Positron-Emission Tomography, Pyrazines, Molecular Medicine, Benzimidazoles, Female, PDE10A, Chromatography, Liquid, Papio, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2114c0263395e74897b10174822cf2a
https://pubmed.ncbi.nlm.nih.gov/25502803

المؤلفون: Hong Sun, David C. Immke, Sonya G. Lehto, Licheng Shi, Dawn Zhu, Cen Xu, Kenneth D. Wild, S Rao, C King

المصدر: The Journal of Headache and Pain

مصطلحات موضوعية: Pathology, medicine.medical_specialty, business.industry, medicine.drug_class, Clinical Neurology, Antagonist, Camp production, General Medicine, Pharmacology, Monoclonal antibody, Anesthesiology and Pain Medicine, Meeting Abstract, Medicine, Potency, Neurology (clinical), business, Receptor, Inhibitory effect, IC50, CGRP receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645f17a7c667733da39e329681f57125
https://doi.org/10.1186/1129-2377-15-s1-g43

المؤلفون: Brett Janosky, April Chen, Elma Feric, John L. Buchanan, Xingwen Li, Peter Miu, Joseph Ligutti, Liyue Huang, Jeff S. McDermott, Markus Hierl, David C. Immke, David J. Matson, Stefan I. McDonough, Annika B. Malmberg, Dong Liu, Anruo Zou, Erin F. DiMauro, Bingfan Du, Xiao Mei Zheng, Hanh Nho Nguyen, Loren Berry, Vinod F. Patel, Daniel Waldon, Ben Wilenkin, Howard Bregman, Danielle Johnson

المصدر: Journal of medicinal chemistry. 54(13)

مصطلحات موضوعية: ERG1 Potassium Channel, Patch-Clamp Techniques, hERG, Administration, Oral, Pain, Nerve Tissue Proteins, Tetrodotoxin, Pharmacology, In Vitro Techniques, Sodium Channels, Cell Line, chemistry.chemical_compound, Structure-Activity Relationship, In vivo, Oral administration, Formaldehyde, Ganglia, Spinal, Drug Discovery, Acetamides, medicine, Animals, Humans, Patch clamp, Sensitization, Pain Measurement, Neurons, Analgesics, Binding Sites, biology, Chemistry, Triazines, Sodium channel, Potassium channel, Ether-A-Go-Go Potassium Channels, Rats, NAV1.1 Voltage-Gated Sodium Channel, medicine.anatomical_structure, Solubility, biology.protein, Microsomes, Liver, Molecular Medicine, Sodium Channel Blockers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0554d821ede56752ff72b8f427a167f
https://pubmed.ncbi.nlm.nih.gov/21634377

المؤلفون: Weiya Wang, Ella Magal, Charles Henley, Sekhar Surapaneni, James J. S. Treanor, Nadia B. Ernst, Annette Bak, Sonya G. Lehto, Licheng Shi, Gary Zajic, David C. Immke, Gal Hever, Rami Tamir, Anthony W. Bannon, Mark H. Norman, Lana Klionsky, Dawn Zhu, James Davis, Narender R. Gavva, Jue Wang, Leyla Arik, David N. Hovland, Rongzhen Kuang, Jean-Claude Louis

المصدر: The Journal of pharmacology and experimental therapeutics. 323(1)

مصطلحات موضوعية: Hyperthermia, Agonist, Male, Fever, medicine.drug_class, Freund's Adjuvant, TRPV1, Pain, TRPV Cation Channels, CHO Cells, Pharmacology, Drug Administration Schedule, Body Temperature, Rats, Sprague-Dawley, chemistry.chemical_compound, Cricetulus, Desensitization (telecommunications), In vivo, Cricetinae, medicine, Animals, Telemetry, Benzothiazoles, Molecular Structure, Chemistry, Antagonist, Analgesics, Non-Narcotic, medicine.disease, Blockade, Rats, Disease Models, Animal, Macaca fascicularis, Pyrimidines, Capsaicin, Drug Design, Molecular Medicine, lipids (amino acids, peptides, and proteins), Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f156de0392baa42cc12b395266e090
https://pubmed.ncbi.nlm.nih.gov/17652633

المؤلفون: Licheng Shi, Sonya G Lehto, Dawn X D Zhu, Hong Sun, Jianhua Zhang, Brian P Smith, David C Immke, Kenneth D Wild, Cen Xu

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jpet.aspetjournals.org/content/jpet/356/1/223.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1071.7659; http://jpet.aspetjournals.org/content/jpet/356/1/223.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1071.7659
http://jpet.aspetjournals.org/content/jpet/356/1/223.full.pdf

المؤلفون: Licheng Shi, Sonya G Lehto, Dawn X D Zhu, Hong Sun, Jianhua Zhang, Brian P Smith, David C Immke, Kenneth D Wild, Cen Xu, D X D Z, J Z, H S, L S, D C I, K D W

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jpet.aspetjournals.org/content/jpet/early/2015/11/11/jpet.115.227793.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1071.7561; http://jpet.aspetjournals.org/content/jpet/early/2015/11/11/jpet.115.227793.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1071.7561
http://jpet.aspetjournals.org/content/jpet/early/2015/11/11/jpet.115.227793.full.pdf

المؤلفون: David C. Immke, Sonya G. Lehto, Ruoyuan Yin, Chi-Ming Li, Bryan D. Moyer, Dong Liu, Mark Chhoa, Y. Luo, Maosheng Zhang

المصدر: The Journal of Pain. 13:S41

مصطلحات موضوعية: Anesthesiology and Pain Medicine, Neurology, business.industry, Sodium channel, Medicine, Sensory system, Neurology (clinical), business, Neuroscience, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::95a2d7f78fa2dc1cccf1577fdc70a166
https://doi.org/10.1016/j.jpain.2012.01.173

المؤلفون: Edwin W. McCleskey, David C. Immke

المصدر: Nature Neuroscience. 4:869-870

مصطلحات موضوعية: Patch-Clamp Techniques, Ischemia, Pharmacology, Chest pain, chemistry.chemical_compound, Psalmotoxin, medicine, Animals, Lactic Acid, Neurons, Afferent, Patch clamp, Muscle, Skeletal, Acid-sensing ion channel, Acidosis, Neurons, Dose-Response Relationship, Drug, General Neuroscience, Hydrogen-Ion Concentration, medicine.disease, Rats, Lactic acid, chemistry, Lactic acidosis, COS Cells, Calcium Channels, medicine.symptom, Acids, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48eeca05540614dfd3657330cd4062a
https://doi.org/10.1038/nn0901-869

المؤلفون: Mark H. Norman, Rami Tamir, David C. Immke, A. Le, James J. S. Treanor, Brad Youngblood, Dawn Zhu, Ella Magal, Narender R. Gavva, Sonya G. Lehto, Jean Claude Louis

المصدر: European Journal of Pain. 11:S169-S169

مصطلحات موضوعية: Anesthesiology and Pain Medicine, Body Temperature Changes, Chemistry, Magnitude (astronomy), TRPV1, Pharmacology, Differential (mathematics)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::52dedc0d828fa48dc251aa5b24396b72
https://doi.org/10.1016/j.ejpain.2007.03.396

المؤلفون: David C. Immke, Edwin W. McCleskey

المصدر: Neuron. (1):75-84

مصطلحات موضوعية: Cell Membrane Permeability, Neuroscience(all), chemistry.chemical_element, Nerve Tissue Proteins, Calcium, Sodium Channels, chemistry.chemical_compound, Catalytic Domain, Psalmotoxin, Extracellular, medicine, Animals, Calcium Signaling, Lactic Acid, Neurons, Afferent, Ion channel, Acid-sensing ion channel, Calcium signaling, Binding Sites, Chemistry, General Neuroscience, Sodium channel, Cell Membrane, Membrane Proteins, Stereoisomerism, Hydrogen-Ion Concentration, medicine.disease, Chemoreceptor Cells, Acid Sensing Ion Channels, Kinetics, Biochemistry, Lactic acidosis, COS Cells, Biophysics, Protons, Ion Channel Gating

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd21bde8aa6c03096984a7358a24de09

المؤلفون: Michel Paré, Leonardo Fierro, Derek C. Molliver, Edwin W. McCleskey, David C. Immke, Frank L. Rice

المصدر: Molecular Pain
Molecular Pain, Vol 1, Iss 1, p 35 (2005)

مصطلحات موضوعية: Sensory Receptor Cells, Calcitonin Gene-Related Peptide, Fluorescent Antibody Technique, Nerve Tissue Proteins, Sodium Channels, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, Dorsal root ganglion, medicine, lcsh:Pathology, Animals, Receptor, trkC, Receptor, trkA, Acid-sensing ion channel, Skin, Mechanosensation, Chemistry, Muscles, Research, Nociceptors, Sensory neuron, Rats, Acid Sensing Ion Channels, Nerve growth factor, Nociception, medicine.anatomical_structure, Anesthesiology and Pain Medicine, nervous system, Nociceptor, Blood Vessels, Molecular Medicine, Neuroscience, Acids, lcsh:RB1-214

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0e225651c3a4c4ab46f7b9adcb7c22