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1Academic Journal
المؤلفون: Loren Baugh, Larry A Gallagher, Rapatbhorn Patrapuvich, Matthew C Clifton, Anna S Gardberg, Thomas E Edwards, Brianna Armour, Darren W Begley, Shellie H Dieterich, David M Dranow, Jan Abendroth, James W Fairman, David Fox, Bart L Staker, Isabelle Phan, Angela Gillespie, Ryan Choi, Steve Nakazawa-Hewitt, Mary Trang Nguyen, Alberto Napuli, Lynn Barrett, Garry W Buchko, Robin Stacy, Peter J Myler, Lance J Stewart, Colin Manoil, Wesley C Van Voorhis
المصدر: PLoS ONE, Vol 8, Iss 1, p e53851 (2013)
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Crystallization, Darren W. Begley, B Douglas R, B Robert C. Hartley, Stephen N. Hewitt, C Am, D Peter J. Myler, Wesley C. Van Voorhis, G Bart L, Staker A, Lance J. Stewart A
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/54/61/Acta_Crystallogr_Sect_F_Struct_Biol_Cryst_Commun_2011_Aug_13_67(Pt_9)_1060-1069.tar.gz
وصف الملف: application/zip
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3
المؤلفون: Stephen N. Hewitt, Darren W. Begley, R. Meganathan, Hannah S. Udell, Gashaw M. Goshu, Phillip G. Pierce, Peter J. Myler, Joy M. Bain, Debarati Ghose, Timothy J. Hagen
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:5699-5704
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Burkholderia, Pyridines, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Biochemistry, Article, Pyrazolopyrimidine, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Structure–activity relationship, Molecular Biology, chemistry.chemical_classification, Burkholderia thailandensis, biology, Organic Chemistry, Kanamycin, biology.organism_classification, Ligand (biochemistry), Anti-Bacterial Agents, Enzyme, chemistry, Pseudomonas aeruginosa, Pyrazoles, Molecular Medicine, Antibacterial activity, medicine.drug
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4
المصدر: Current Protocols in Chemical Biology
مصطلحات موضوعية: Quality Control, Fragment (logic), Peptide Library, Chemistry, Saturation transfer, Drug discovery, Drug Design, General Medicine, Nuclear Magnetic Resonance, Biomolecular, Combinatorial chemistry, Small molecule, Peptide Fragments, High-Throughput Screening Assays
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5
المؤلفون: Stephen J. Mayclin, Thomas E. Edwards, Amy Sullivan, Bart L. Staker, Isabelle Q. H. Phan, Darren W. Begley, Anna Gardberg, Vasilios M. Marathias, Jan Abendroth, Peter J. Myler, Donald D. Lorimer, Daniel H. Haft, Phillip G. Pierce
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Magnetic Resonance Spectroscopy, Protein Conformation, Coenzymes, Dehydrogenase, Cyclohexane Monoterpenes, Biology, Crystallography, X-Ray, Cofactor, Article, 03 medical and health sciences, Oxidoreductase, Humans, chemistry.chemical_classification, Short-chain dehydrogenase, Cofactor binding, Multidisciplinary, Binding Sites, Mycobacterium tuberculosis, NAD, NAD binding, Mutagenesis, Insertional, Thiazoles, 030104 developmental biology, Glycerol-3-phosphate dehydrogenase, Biochemistry, chemistry, biology.protein, Monoterpenes, 2,6-Dichloroindophenol, NAD+ kinase, Oxidoreductases, Protein Binding
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6
المؤلفون: Bart L. Staker, Lance Stewart, Robert C. Hartley, Thomas E. Edwards, Amy C. Raymond, Darren W. Begley, Banumathi Sankaran, Eric R. Smith, Peter J. Myler, Donald D. Lorimer, Jan Abendroth
المصدر: Acta Crystallographica Section F: Structural Biology and Crystallization Communications
مصطلحات موضوعية: Models, Molecular, Biophysics, SSGCID, Crystallography, X-Ray, Ligands, Biochemistry, Thymidylate synthase, Substrate Specificity, Microbiology, chemistry.chemical_compound, dihydrofolate reductase, Multienzyme Complexes, Structural Biology, antifolates, parasitic diseases, Dihydrofolate reductase, Genetics, medicine, Structural Communications, Enzyme Inhibitors, pemetrexed, Protein Structure, Quaternary, chemistry.chemical_classification, biology, raltitrexed, Plasmodium falciparum, Babesia bovis, Babesiosis, Thymidylate Synthase, Condensed Matter Physics, biology.organism_classification, medicine.disease, Protein Structure, Tertiary, Tetrahydrofolate Dehydrogenase, Enzyme, chemistry, Structural Homology, Protein, Babesia, Antifolate, biology.protein, Apoproteins, Protein Binding
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7
المؤلفون: Christian Olsen, Wenjin Guo, Thomas E. Edwards, Isabelle Phan, Ariel Abramov, Peter J. Myler, Micah Ferrell, W. C. Van Voorhis, Lance Stewart, Kaitlin Thompkins, Darren W. Begley, Banumathi Sankaran, Yang Zhang, Robin Stacy, Alberto J. Napuli
المصدر: Acta Crystallographica Section F: Structural Biology and Crystallization Communications
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Mycobacterium thermoresistible, Molecular Sequence Data, Biophysics, Flavin mononucleotide, Flavin group, Protomer, SSGCID, Biochemistry, Cofactor, Mixed Function Oxygenases, Mycobacterium, chemistry.chemical_compound, Structural Biology, Genetics, Structural Communications, Amino Acid Sequence, Conserved Sequence, biology, Active site, Condensed Matter Physics, biology.organism_classification, Mycobacterium thermoresistibile, oxidoreductases, Protein Structure, Tertiary, chemistry, biology.protein, Nitrilotriacetate monooxygenase, Energy source, flavin reductases, Sequence Alignment, nitrilotriacetate monooxygenase component B
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8
المؤلفون: Bart L. Staker, Lance Stewart, Peter J. Myler, Robert C. Hartley, Stephen N. Hewitt, Wesley C. Van Voorhis, Amanda L. Rychel, Darren W. Begley, Douglas R. Davies
المصدر: Acta Crystallographica Section F: Structural Biology and Crystallization Communications
مصطلحات موضوعية: Models, Molecular, Burkholderia pseudomallei, Biophysics, Flavoprotein, Glutaryl-CoA dehydrogenase, Dehydrogenase, Biology, Crystallography, X-Ray, SSGCID, glutaryl-CoA, Biochemistry, Cofactor, chemistry.chemical_compound, Apoenzymes, Structural Biology, Catalytic Domain, glutaric acidemia, Genetics, Humans, Structural Communications, Protein Structure, Quaternary, Ternary complex, Phylogeny, Flavin adenine dinucleotide, Cofactor binding, Glutaryl-CoA Dehydrogenase, flavoproteins, flavin adenine dinucleotide, fragment screening, Condensed Matter Physics, chemistry, Structural Homology, Protein, pantothenate, biology.protein, crotonyl-CoA, Glutaric Acidemia Type 1
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9
المؤلفون: Gabriele Varani, Darren W. Begley, Bart L. Staker, Garry W. Buchko, Peter J. Myler, Robin Stacy, Wesley C. Van Voorhis, Isabelle Phan, Lance Stewart
المصدر: Acta Crystallographica Section F
Acta Crystallographica Section F Structural Biology and Crystallization Communicationsمصطلحات موضوعية: Introduction, Extramural, business.industry, emerging and re-emerging diseases, education, Biophysics, Genomics, pathogens, Computational biology, Biology, structural genomics, Condensed Matter Physics, SSGCID, infectious diseases, Biochemistry, Structural genomics, Biotechnology, Structural Biology, Infectious disease (medical specialty), Genetics, structure-based drug design, National laboratory, business, health care economics and organizations
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10
المؤلفون: Darren W. Begley, Erkang Fan, J. Liu, Daniel D. Mitchell, Christophe L. M. J. Verlinde, Gabriele Varani
المصدر: Chemical Biology & Drug Design. 71:408-419
مصطلحات موضوعية: Pharmacology, Stereochemistry, Toxin, Chemistry, Pentamer, Organic Chemistry, Cholera toxin, Ligand (biochemistry), medicine.disease_cause, Biochemistry, Drug Discovery, medicine, Molecular Medicine, Molecule, Receptor, Linker, Protein ligand
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11
المؤلفون: David M. Dranow, Loren Baugh, David A. Fox, Dmitri Serbzhinskiy, Robin Stacy, Stephen N. Hewitt, Marvin M. Muruthi, Matthew C. Clifton, Ryan Choi, Darren W. Begley, Ngoc Tran, Wesley C. Van Voorhis, Sally Lyons-Abbott, Don Lorimer, Jan Abendroth, Ariel Abramov, Bart L. Staker, Alberto J. Napuli, Katie Thompkins, Brandy M. Taylor, Isabelle Phan, Shellie H. Dieterich, James W. Fairman, Elizabeth Mundt, Yang Zhang, Garry W. Buchko, Aarthi Sekar, Brianna Armour, Lynn K. Barrett, Peter J. Myler, Janette B. Myers, Thomas E. Edwards, Anna Gardberg, Micah Ferrell, Lance Stewart
مصطلحات موضوعية: Microbiology (medical), Models, Molecular, Tuberculosis, Immunology, Antitubercular Agents, Quantitative Structure-Activity Relationship, Computational biology, Crystallography, X-Ray, Microbiology, Article, Structural genomics, Mycobacterium, Mycobacterium tuberculosis, Bacterial Proteins, Species Specificity, Hydrolase, medicine, Humans, Molecular Targeted Therapy, Databases, Protein, biology, Drug discovery, Active site, Computational Biology, Genomics, biology.organism_classification, medicine.disease, Enzyme Activation, Infectious Diseases, Biochemistry, Drug Design, Proteome, biology.protein, Cytidylate kinase
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12
المؤلفون: Jennifer L. Kirkwood, Thomas E. Edwards, Amy C. Raymond, Bart L. Staker, Jan Abendroth, James W. Fairman, Spencer O. Moen, Greg Henkel, Robin Stacy, Ken McCormack, Darren W. Begley, Ruth Baydo, Vincent C. Tam, Jameson Bullen, Steve R. Barnes, Isabelle Phan, Don Lorimer, Peter J. Myler
المصدر: Scientific Reports
مصطلحات موضوعية: Models, Molecular, animal structures, Viral protein, viruses, Molecular Sequence Data, Gene Expression, Peptide, RNA polymerase complex, Crystallography, X-Ray, Influenza A Virus, H7N9 Subtype, Virus Replication, medicine.disease_cause, Protein Structure, Secondary, Article, Viral Proteins, Influenza A Virus, H1N1 Subtype, Immune system, Transcription (biology), Enzyme Stability, Escherichia coli, Influenza A virus, medicine, Amino Acid Sequence, Polymerase, chemistry.chemical_classification, Binding Sites, Multidisciplinary, biology, virus diseases, biochemical phenomena, metabolism, and nutrition, RNA-Dependent RNA Polymerase, Virology, Recombinant Proteins, Protein Structure, Tertiary, chemistry, biology.protein, Viral genome replication, Protein Binding
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13
المؤلفون: Thomas E. Edwards, Mitali Sarkar-Tyson, Donald D. Lorimer, Bart L. Staker, Nicholas J. Harmer, Dominic C. Jenner, Muigai Muruthi, Jan Abendroth, Kris Safford, Amy C. Raymond, Vanessa Anderson, Ulrike Holzgrabe, Robin Stacy, Spencer O. Moen, Darren W. Begley, David A. Fox, Isobel H. Norville, Christina Juli, Phillip G. Pierce, Peter J. Myler, Kateri Atkins, Steve R. Barnes
المصدر: Antimicrobial agents and chemotherapy. 58(3)
مصطلحات موضوعية: Burkholderia pseudomallei, Virulence Factors, Virulence, Biology, medicine.disease_cause, Crystallography, X-Ray, Microbiology, Immunophilins, Anti-Infective Agents, Bacterial Proteins, Drug Discovery, medicine, Pharmacology (medical), Experimental Therapeutics, Binding site, Nuclear Magnetic Resonance, Biomolecular, Pharmacology, Binding Sites, Drug discovery, Pathogenic bacteria, Potentiator, biology.organism_classification, Infectious Diseases, Structural biology, Biochemistry
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14
المؤلفون: Thomas E. Edwards, Darren W. Begley, Zheng Zhang, Kenneth Gogol, Bart L. Staker, Lei Zhao, Peter J. Myler, Sriram Jakkaraju, Robert C. Hartley, Timothy J. Hagen, Joy M. Blain, James R. Horn, Michael Clare, Courtney A. Karlsson, Lance Stewart
مصطلحات موضوعية: Stereochemistry, Burkholderia, Clinical Biochemistry, Pharmaceutical Science, Plasma protein binding, Cytidine, Crystallography, X-Ray, Biochemistry, Article, chemistry.chemical_compound, Bacterial Proteins, Drug Discovery, Moiety, Binding site, Molecular Biology, Cytidine diphosphate, chemistry.chemical_classification, Binding Sites, ATP synthase, biology, Organic Chemistry, Surface Plasmon Resonance, Lyase, Anti-Bacterial Agents, Protein Structure, Tertiary, Molecular Docking Simulation, Enzyme, chemistry, biology.protein, Molecular Medicine, Protein Binding
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15
المؤلفون: Donald D. Lorimer, Darren W. Begley, Brianna Armour, Thomas E. Edwards, Steve R. Barnes, Lance Stewart, Amy C. Raymond, Eric R. Smith, Spencer O. Moen, Bart L. Staker, James W. Fairman
المصدر: Journal of Visualized Experiments : JoVE
مصطلحات موضوعية: Models, Molecular, protein crystallization, General Chemical Engineering, Crystallography, X-Ray, medicine.disease_cause, Protein Structure, Secondary, Influenza A Virus, H1N1 Subtype, Structural Biology, Pandemic, Influenza A virus, fermentation, General Neuroscience, Genomics, sequencing, Infectious Diseases, PCR, Drug development, Medicine, protein production, Gene Composer, Infection, influenza, purification, medicine.drug_class, Biomedical Engineering, high throughput, virus, Biology, Microbiology, General Biochemistry, Genetics and Molecular Biology, Structural genomics, Viral Proteins, Virology, plasmid, expression, Genetics, medicine, Molecular Biology, Issue 76, X-ray crystallography, cell culture, Influenza A Virus, H5N1 Subtype, General Immunology and Microbiology, Influenza A Virus, H3N2 Subtype, E. coli, Outbreak, structural genomics, cell, multi-targeting, RNA-Dependent RNA Polymerase, Protein Subunits, Infectious disease (medical specialty), Protein Maker, Antiviral drug, vector
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16
المصدر: Methods in enzymology. 493
مصطلحات موضوعية: Models, Molecular, Phosphoglycerate Mutase, Burkholderia pseudomallei, Glutaryl-CoA Dehydrogenase, Drug Evaluation, Preclinical, Genomics, Crystallography, X-Ray, Ligands, Communicable Diseases, Isoenzymes, Small Molecule Libraries, Erythritol, 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase, Drug Discovery, Solvents, Computer Simulation, Phosphorus-Oxygen Lyases, Crystallization, Algorithms, Protein Binding
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17
المؤلفون: Darren W. Begley, Gabriele Varani, Amy Davidson, Carmen Lau
المصدر: Journal of molecular biology. 410(5)
مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Chemistry, Anti-HIV Agents, Small Molecule Libraries, RNA, Nuclear magnetic resonance spectroscopy, Ligand (biochemistry), Molecular biology, Small molecule, Article, Structural Biology, Molecular Probes, Biophysics, Nucleic Acid Conformation, RNA, Viral, HIV Long Terminal Repeat, Molecular probe, Molecular Biology, Two-dimensional nuclear magnetic resonance spectroscopy
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18
المؤلفون: Robert C. Hartley, Thomas E. Edwards, Darren W. Begley, Douglas R. Davies, Lance Stewart, Peter J. Myler, Bart L. Staker, Wesley C. Van Voorhis
مصطلحات موضوعية: Protein function, Drug discovery, Computational Biology, Small Molecule Libraries, Genomics, Computational biology, Biology, Crystallography, X-Ray, Ligands, Bioinformatics, Communicable Diseases, Article, Structural genomics, Protein structure, Bacterial Proteins, Functional annotation, Infectious disease (medical specialty), Drug Discovery, Phosphorus-Oxygen Lyases, Crystallization
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19
مصطلحات موضوعية: Fragment (logic), Drug discovery, Chemistry, Small Molecule Libraries, Current technology, Computational biology, Protein target, Combinatorial chemistry
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20
المؤلفون: Suxin Zheng, Gabriele Varani, Darren W. Begley
المصدر: Chemical Biology & Drug Design.
مصطلحات موضوعية: Pharmacology, Chemistry, Organic Chemistry, Nuclear magnetic resonance spectroscopy, AutoDock, Ligand (biochemistry), Biochemistry, Combinatorial chemistry, Small molecule, Epitope mapping, Protein structure, Drug Discovery, Molecular Medicine, Structure–activity relationship, Binding site
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