نتائج البحث - "Daphne S. Bindels"

1

Academic Journal

Aequorea's secrets revealed: New fluorescent proteins with unique properties for bioimaging and biosensing.

المؤلفون: Gerard G Lambert, Hadrien Depernet, Guillaume Gotthard, Darrin T Schultz, Isabelle Navizet, Talley Lambert, Stephen R Adams, Albertina Torreblanca-Zanca, Meihua Chu, Daphne S Bindels, Vincent Levesque, Jennifer Nero Moffatt, Anya Salih, Antoine Royant, Nathan C Shaner

المصدر: PLoS Biology, Vol 18, Iss 11, p e3000936 (2020)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

URL الوصول: https://doaj.org/article/1615fde95fbf4dc185013abf874918db

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2

Quantitative Determination of Dark Chromophore Population Explains the Apparent Low Quantum Yield of Red Fluorescent Proteins

المؤلفون: Laura van Weeren, Christian Blum, Jente Stouthamer, Daphne S. Bindels, Vinod Subramaniam, Theodorus W. J. Gadella, Jord C. Prangsma, Robert Molenaar, Lindsay Haarbosch, Willem L. Vos

المساهمون: Molecular Cytology (SILS, FNWI), Nanobiophysics, Complex Photonic Systems

المصدر: The journal of Physical Chemistry. B, 124(8), 1383-1391. American Chemical Society
The Journal of physical chemistry B, 124(8), 1383-1391. American Chemical Society
The Journal of Physical Chemistry. B

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad0e66dc22d8c7cbe52819b9650c8bc
https://doi.org/10.1021/acs.jpcb.9b10396

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3

Multiparameter screening method for developing optimized red-fluorescent proteins

المؤلفون: Lindsay Haarbosch, Daphne S. Bindels, Marten Postma, Laura van Weeren, Theodorus W. J. Gadella

المساهمون: Molecular Cytology (SILS, FNWI)

المصدر: Nature Protocols, 15(2), 450-478. Nature Publishing Group

مصطلحات موضوعية: 0303 health sciences, Mutagenesis (molecular biology technique), Computational biology, Fluorescence, General Biochemistry, Genetics and Molecular Biology, Cell Line, Luminescent Proteins, 03 medical and health sciences, 0302 clinical medicine, Förster resonance energy transfer, Mutagenesis, Mammalian cell, Screening method, Animals, Biosensor, 030217 neurology & neurosurgery, 030304 developmental biology, Bacterial colony

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfae30009e7818834a2915c90a768542
https://doi.org/10.1038/s41596-019-0250-7

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4

The Endoplasmic Reticulum Proteostasis Regulator ATF6 is Essential for Human Cone Photoreceptor Development

المؤلفون: Wei-Chieh Chiang, R. Luke Wiseman, Joseph Carroll, Amanda Nguyen, Julia M. D. Grandjean, Heike Kroeger, Jennifer Okalova, Jonathan H. Lin, Neil Grimsey, Evan T. Powers, Michel Michaelides, Jeffery W. Kelly, Daphne S. Bindels, Rebecca Mastey

مصطلحات موضوعية: genetic structures, ATF6, Endoplasmic reticulum, Activating transcription factor, Retinal, Biology, Cell biology, chemistry.chemical_compound, Proteostasis, chemistry, Unfolded protein response, Organoid, sense organs, Visual phototransduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::913b5b7d900ab5ff510d3883f7ce149e
https://doi.org/10.1101/2020.10.04.325019

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5

Proteostasis Modulation Prevents Photoreceptor Pathology in Retinal Organoids

المؤلفون: Daphne S. Bindels, Amanda Nguyen, Jonathan H. Lin, Julia M. D. Grandjean, Wei-Chieh Chiang, Rebecca Mastey, Michel Michaelides, Evan T. Powers, Jeffery W. Kelly, Joseph Carroll, Heike Kroeger, R. Luke Wiseman, Jennifer Okalova, Neil Grimsey

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Pathology, medicine.medical_specialty, genetic structures, ATF6, Endoplasmic reticulum, Retinal, Biology, chemistry.chemical_compound, Proteostasis, chemistry, Unfolded protein response, medicine, Organoid, sense organs, Induced pluripotent stem cell, Visual phototransduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ecf0e3fc0f7e1e9394554248171388bb
https://doi.org/10.2139/ssrn.3746623

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6

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)

المؤلفون: P. Boronat, Louis Maes, I.J.P. de Esch, Marco Siderius, David G. Brown, Rob Leurs, A.R. Blaazer, Payman Sadek, Geert Jan Sterk, E. de Heuvel, Daphne S. Bindels, M. Oberholzer, Albert J. Kooistra, Nathan C. Shaner, T. van der Meer, Guy Caljon, A.K. Singh

المساهمون: AIMMS, Medicinal chemistry, Innovations in Human Health & Life Sciences, Chemistry and Pharmaceutical Sciences

المصدر: Bioorganic and Medicinal Chemistry, 27(18), 4013-4029. Elsevier Limited
de Heuvel, E, Singh, A K, Boronat, P, Kooistra, A J, van der Meer, T, Sadek, P, Blaazer, A R, Shaner, N C, Bindels, D S, Caljon, G, Maes, L, Sterk, G J, Siderius, M, Oberholzer, M, de Esch, I J P, Brown, D G & Leurs, R 2019, ' Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2) ', Bioorganic and Medicinal Chemistry, vol. 27, no. 18, pp. 4013-4029 . https://doi.org/10.1016/j.bmc.2019.06.026
Bioorganic and medicinal chemistry

مصطلحات موضوعية: Phosphodiesterase Inhibitors, Clinical Biochemistry, Protozoan Proteins, Pharmaceutical Science, PROTEIN, Chemistry, Medicinal, Trypanosoma brucei phosphodiesterase B1, Biochemistry, TRYPANOSOMA-BRUCEI PHOSPHODIESTERASES, Drug Discovery, Pharmacology & Pharmacy, DOCKING, Cytotoxicity, FRAGMENT, Fluorescence microscopy, 0303 health sciences, biology, Chemistry, Pharmacology. Therapy, Phosphodiesterase, Enzyme inhibitors, Cell cycle, 3. Good health, Structure-based drug discovery, Physical Sciences, Molecular Medicine, Life Sciences & Biomedicine, Intracellular, EXPRESSION, Programmed cell death, Biochemistry & Molecular Biology, 030303 biophysics, Neglected tropical disease, Chemistry, Organic, Trypanosoma brucei, 03 medical and health sciences, Structure-Activity Relationship, SDG 3 - Good Health and Well-being, Hydrolase, DRUGGABLE TARGETS, Humans, Mode of action, Molecular Biology, Biology, 030304 developmental biology, DRUG-RESISTANCE, Science & Technology, ANALOGS, Organic Chemistry, Human African trypanosomiasis, biology.organism_classification, 3',5'-Cyclic-AMP Phosphodiesterases, PHARMACOLOGICAL VALIDATION, AFRICAN TRYPANOSOMIASIS