المؤلفون: Ninghui Mao, Zeda Zhang, Young Sun Lee, Danielle Choi, Aura Agudelo Rivera, Dan Li, Cindy Lee, Samuel Haywood, Xiaoping Chen, Qing Chang, Guotai Xu, Hsuan-An Chen, Elisa de Stanchina, Charles Sawyers, Neal Rosen, Andrew C. Hsieh, Yu Chen, Brett S. Carver

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/907e2e85e15748fa85c06a824495c169

المؤلفون: Eugine Lee, John Wongvipat, Danielle Choi, Ping Wang, Young Sun Lee, Deyou Zheng, Philip A Watson, Anuradha Gopalan, Charles L Sawyers

المصدر: eLife, Vol 8 (2019)

مصطلحات موضوعية: intra-tumoral heterogeneity, AR signaling output, AR coactivator, enzalutamide, GREB1, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/41913; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/a9ce9b1a721845688d664f179362cf94

المؤلفون: Brett S. Carver, Yu Chen, Anuradha Gopalan, Charles L. Sawyers, Neal Rosen, Danielle Choi, Zeda Zhang, Patrick Sullivan, Young Sun Lee, Shangqian Wang, Haley Hieronymus, Sunyana Gadal, Wenhuo Hu, Dong Gao, Ninghui Mao

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac284ed09485d312252cc3d4ae5e0fc8
https://doi.org/10.1158/0008-5472.22426321

المؤلفون: Brett S. Carver, Yu Chen, Anuradha Gopalan, Charles L. Sawyers, Neal Rosen, Danielle Choi, Zeda Zhang, Patrick Sullivan, Young Sun Lee, Shangqian Wang, Haley Hieronymus, Sunyana Gadal, Wenhuo Hu, Dong Gao, Ninghui Mao

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aabd2d2fb63da659913b574b2aa663f2
https://doi.org/10.1158/0008-5472.c.6512302.v1

المؤلفون: Brett S. Carver, Yu Chen, Anuradha Gopalan, Charles L. Sawyers, Neal Rosen, Danielle Choi, Zeda Zhang, Patrick Sullivan, Young Sun Lee, Shangqian Wang, Haley Hieronymus, Sunyana Gadal, Wenhuo Hu, Dong Gao, Ninghui Mao

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70da04c32528f3aca2f277f9c7b94c1b
https://doi.org/10.1158/0008-5472.22426318.v1

المؤلفون: Hsuan-An Chen, Samuel Haywood, Ninghui Mao, Neal Rosen, Zeda Zhang, Brett S. Carver, Charles L. Sawyers, Dan Li, Qing Chang, Andrew C. Hsieh, Elisa de Stanchina, Xiaoping Chen, Danielle Choi, Yu Chen, Young Sun Lee, Cindy Lee, Aura Agudelo Rivera, Guotai Xu

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications

مصطلحات موضوعية: Male, Science, General Physics and Astronomy, Context (language use), P110α, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, Receptor, IGF Type 1, Mice, Phosphatidylinositol 3-Kinases, Targeted therapies, Downregulation and upregulation, Cell Line, Tumor, PTEN, Animals, Humans, Phosphorylation, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Insulin-like growth factor 1 receptor, Feedback, Physiological, Multidisciplinary, Prostate cancer, biology, PTEN Phosphohydrolase, Prostatic Neoplasms, food and beverages, General Chemistry, Up-Regulation, Isoenzymes, Organoids, Cancer research, biology.protein, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed600065b6e9a2c5d108bd0f87fa1a6
https://doaj.org/article/907e2e85e15748fa85c06a824495c169

المؤلفون: Moshe Biton, Mesruh Turkekul, Charles L. Sawyers, Anuradha Gopalan, Matan Hofree, Alborz Bejnood, Vincent P. Laudone, Wassim Abida, Katia Manova, Ignas Masilionis, Eliot Linton, Ojasvi Chaudhary, Linas Mazutis, Tianhao Xu, Wouter R. Karthaus, Brett S. Carver, Dana Pe'er, Danielle Choi, Aviv Regev

المصدر: Science. 368:497-505

مصطلحات موضوعية: Male, Cellular differentiation, Population, Gene Expression, Biology, GPI-Linked Proteins, Androgen-Binding Protein, Mice, Prostate cancer, Paracrine signalling, Antigens, Neoplasm, Prostate, medicine, Animals, Humans, Regeneration, Nerve Growth Factors, education, Ataxin-1, Homeodomain Proteins, education.field_of_study, Multidisciplinary, Sequence Analysis, RNA, Mesenchymal stem cell, Prostatic Neoplasms, Androgen Antagonists, Cell Differentiation, Mesenchymal Stem Cells, Organ Size, medicine.disease, Neoplasm Proteins, Organoids, medicine.anatomical_structure, Androgens, Cancer research, Prostate surgery, Single-Cell Analysis, Stem cell, Thrombospondins, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576dfe85f3ace5428c5e6cc7b6837898
https://doi.org/10.1126/science.aay0267

المؤلفون: Charles L. Sawyers, Danielle Choi, Sunyana Gadal, Dong Gao, Wenhuo Hu, Yu Chen, Young Sun Lee, Neal Rosen, Anuradha Gopalan, Zeda Zhang, Brett S. Carver, Patrick F. Sullivan, Ninghui Mao, Haley Hieronymus, Shangqian Wang

المصدر: Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, DNA Copy Number Variations, Carcinogenesis, Primary Cell Culture, Down-Regulation, Biology, medicine.disease_cause, Article, Gene Knockout Techniques, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Transcriptional Regulator ERG, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, PTEN, RNA-Seq, Promoter Regions, Genetic, Protein kinase B, Gene Rearrangement, Oncogene Proteins, PTEN Phosphohydrolase, Prostate, Prostatic Neoplasms, Cell migration, Gene signature, medicine.disease, Xenograft Model Antitumor Assays, Phenotype, Gene Expression Regulation, Neoplastic, Disease Models, Animal, 030104 developmental biology, Oncology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Insulin Receptor Substrate Proteins, Cancer research, biology.protein, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f8c0705706d9e7320f341c71b81c32
https://doi.org/10.1158/0008-5472.can-19-1394

المؤلفون: Dong Gao, Anuradha Gopalan, Brett S. Carver, Haley Hieronymus, Danielle Choi, Ninghui Mao, Young Sun Lee, Yu Chen, Wenhuo Hu, Cindy Lee, Shangqian Wang

المصدر: Molecular Cancer Therapeutics. 18:1577-1586

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_treatment, Mice, Transgenic, Context (language use), Mice, SCID, Biology, TMPRSS2, Article, Targeted therapy, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Transcriptional Regulator ERG, Cell Line, Tumor, Nitriles, Phenylthiohydantoin, medicine, Animals, Humans, PTEN, Protein kinase B, PI3K/AKT/mTOR pathway, Mice, Knockout, Imidazoles, PTEN Phosphohydrolase, Prostatic Neoplasms, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, Receptors, Androgen, 030220 oncology & carcinogenesis, Benzamides, Quinolines, Cancer research, biology.protein, Erg, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da03664de1467c623f98e65976487824
https://doi.org/10.1158/1535-7163.mct-18-1386

المؤلفون: Charles L. Sawyers, Teng Han, Danielle Choi, Brett S. Carver, Aura Agudelo Rivera, Rodrigo Romero, Huiyong Zhao, Qiao Wang, Maria Jasin, Elisa de Stanchina, Weiran Feng, Zhen Cao, Young Sun Lee, Pei Xin Lim, Hanzhi Luo, Chao Wu, Ninghui Mao

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Male, Cell type, Medical Sciences, Mice, Transgenic, Computational biology, Biology, Transcriptional Regulator ERG, In vivo, CRISPR-Associated Protein 9, Animals, Humans, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Genes, Tumor Suppressor, Guide RNA, organoids, Adaptor Proteins, Signal Transducing, Gene Editing, Multidisciplinary, editing, Prostate, Prostatic Neoplasms, Epithelial Cells, Biological Sciences, Xenograft Model Antitumor Assays, Phenotype, Mice, Inbred C57BL, Ribonucleoproteins, Genetically Engineered Mouse, Cancer cell, cancer modeling, Chromosome Deletion, Ex vivo, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c59513cefba23d84bf7329e482787e9
https://doi.org/10.1073/pnas.2110344118

المؤلفون: Michael Waters, Stanley Stasiewicz, B. Alex Merrick, Kenneth Tomer, Pierre Bushel, Richard Paules, Nancy Stegman, Gerald Nehls, Kenneth J. Yost, C. Harris Johnson, Scott F. Gustafson, Hya Xirasagar, Nianqing Xiao, Cheng-cheng Huang, Paul Boyer, Denny D. Chan, Qinyan Pan, Hui Gong, John Taylor, Danielle Choi, Asif Rashid, Ayazaddin Ahmed, Reese Howle, James Selkirk, Raymond Tennant, Jennifer Fostel

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://nar.oxfordjournals.org/content/36/suppl_1/D892.full-text-lowres.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.492.9103; http://nar.oxfordjournals.org/content/36/suppl_1/D892.full-text-lowres.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.492.9103
http://nar.oxfordjournals.org/content/36/suppl_1/D892.full-text-lowres.pdf

المؤلفون: Anuradha Gopalan, Zeda Zhang, Charles L. Sawyers, Katia Manova-Todorova, Huiyong Zhao, Brett S. Carver, Dana E. Rathkopf, Jose Mauricio Mota, Steven P. Balk, Eugine Lee, Young Sun Lee, Chao Wu, Ping Mu, Wouter R. Karthaus, John Wongvipat, Ninghui Mao, Elisa de Stanchina, Menghan Liu, Vianne R. Gao, Xuejun Jiang, Xiaoping Chen, Wassim Abida, Danielle Choi, Mary-Ellen Taplin, Spencer D. Barnes, Philip A. Watson, Joshua W. Russo, Eliot Linton, Hsuan An Chen

المصدر: Cancer cell. 38(2)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, medicine.drug_class, Antiandrogens, medicine.medical_treatment, Neuregulin-1, Kaplan-Meier Estimate, Mice, SCID, urologic and male genital diseases, Antiandrogen, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Cancer-Associated Fibroblasts, Prostate, Cell Line, Tumor, medicine, Tumor Microenvironment, Animals, Humans, Neuregulin 1, Antiandrogen Therapy, Cells, Cultured, Cell Proliferation, Tumor microenvironment, biology, business.industry, Gene Expression Profiling, Prostatic Neoplasms, Androgen Antagonists, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Hormone therapy, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae367b4294f0e9db4f1686dce124a55b
https://pubmed.ncbi.nlm.nih.gov/32782364

المؤلفون: Charles L. Sawyers, Kyrie J Pappas, Danielle Choi, Wouter R. Karthaus

المصدر: J Vis Exp

مصطلحات موضوعية: Male, Genotype, General Chemical Engineering, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, In vivo, Prostate, Organoid, medicine, Animals, Humans, CRISPR, 030304 developmental biology, 0303 health sciences, General Immunology and Microbiology, General Neuroscience, Cell Differentiation, medicine.disease, Organoids, Disease Models, Animal, medicine.anatomical_structure, Cell culture, 030220 oncology & carcinogenesis, Genetically Engineered Mouse, Mutation, Cancer research, Stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6185e516136ab1b69f928caf3026e0
https://doi.org/10.3791/60346

المؤلفون: Samir Zaidi, Brett S. Carver, Wouter R. Karthaus, Charles L. Sawyers, Aura Agudelo Rivera, Anuradha Gopalan, Jimmy L. Zhao, Dana E. Rathkopf, Yu Chen, Wassim Abida, David W. Goodrich, Danielle Choi, Joseph M. Chan, Howard I. Scher, Kristine M. Wadosky, Dana Pe'er

المصدر: Cancer Research. 80:PO-134

مصطلحات موضوعية: Cancer Research, education.field_of_study, Cell of origin, Population, Cancer, Biology, Cell cycle, medicine.disease, Prostate cancer, Oncology, SOX2, medicine, Cancer research, biology.protein, Adenocarcinoma, PTEN, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf2592a591f2ea1e4cb99ae19fce8de3
https://doi.org/10.1158/1538-7445.tumhet2020-po-134

المؤلفون: Wouter R. Karthaus, Moshe Biton, Ojasvi Chaudhary, Danielle Choi, Linas Mazutis, Matan Hofree, Charles L. Sawyers, Eliot Linton, Ignas Masilionis, Dana Pe'er, Mesruh Turkekul, Vincent P. Laudone, Anuhandra Gopalan, Alborz Bejnood, Aviv Regev, Brett S. Carver

المصدر: Cancer Research. 80:5722-5722

مصطلحات موضوعية: Cancer Research, RSPO3, medicine.drug_class, Regeneration (biology), Cell, Mesenchymal stem cell, Cancer, Biology, medicine.disease, Androgen, medicine.anatomical_structure, Oncology, Prostate, Cancer research, medicine, Stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad5cd5a62096d7287cd5c9183d2a13ff
https://doi.org/10.1158/1538-7445.am2020-5722

المؤلفون: Danielle Choi, Anuradha Gopalan, Deyou Zheng, Eugine Lee, Young Sun Lee, Philip A. Watson, Ping Wang, John Wongvipat, Sawyers Charles L

المصدر: eLife, Vol 8 (2019)
eLife

مصطلحات موضوعية: 0301 basic medicine, QH301-705.5, medicine.drug_class, AR coactivator, Science, Antiandrogen, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Downregulation and upregulation, Coactivator, medicine, Enzalutamide, Biology (General), Cancer Biology, Gene knockdown, enzalutamide, General Immunology and Microbiology, Chemistry, General Neuroscience, AR signaling output, General Medicine, medicine.disease, 3. Good health, Androgen receptor, GREB1, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Medicine, intra-tumoral heterogeneity, Research Article, Human

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5d6fb69547831d294a9b086104661d
https://doi.org/10.7554/elife.41913

المؤلفون: Xiaoping Chen, Carla Rodriguez Tirado, Choushi Wang, Chuanli Zhou, Eliot Linton, Yanxiao Zhang, Lauren A. Metang, Young Sun Lee, Chun-Hao Huang, Su Deng, Yupu Liang, Xiaoling Li, Nickolas A. Johnson, Elisa de Stanchina, Sheng Li, Zhen Cao, Amaia Lujambio, Wassim Abida, Kristina Navrazhina, Scott W. Lowe, Danielle Choi, Spencer D. Barnes, Venkat S. Malladi, Charles L. Sawyers, Chao Wu, Ping Mu, John Wongvipat, Elizabeth Hoover, Joshua T. Mendell, Chi-Chao Chen, Zeda Zhang, Christopher E. Mason

المصدر: Cancer Cell

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_treatment, lineage plasticity, Apoptosis, chromatin remodeling, Targeted therapy, Small hairpin RNA, Transcriptome, Mice, Prostate cancer, 0302 clinical medicine, tumor heterogeneity, Tumor Cells, Cultured, castration-resistant prostate cancer, CRISPR, NR3C1 (GR), RNA, Small Interfering, TBX2, POU3F2 (BRN2), Chromatin, Cell biology, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Prostatic Neoplasms, Castration-Resistant, Oncology, Receptors, Androgen, 030220 oncology & carcinogenesis, Biology, Article, Chromatin remodeling, 03 medical and health sciences, Biomarkers, Tumor, medicine, Animals, Humans, Transcription factor, Cell Proliferation, antiandrogen resistantce, DNA Helicases, Androgen Antagonists, CHD1, medicine.disease, Xenograft Model Antitumor Assays, NR2F1, High-Throughput Screening Assays, 030104 developmental biology, Drug Resistance, Neoplasm, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c7e7c8b4cda7be45d6a2c3c533d59c
https://doi.org/10.1016/j.ccell.2020.03.001

المؤلفون: Danielle Choi, Deyou Zheng, Eugine Lee, Young Sun Lee, Ping Wang, Charles L. Sawyers, John Wongvipat, Philip A. Watson, Anuradha Gopalan

مصطلحات موضوعية: GREB1, Androgen receptor, medicine.drug_class, business.industry, medicine, Cancer research, Cancer, Antiandrogen, medicine.disease, business, Human prostate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3b3b426744ed8ec33093af179c637e57
https://doi.org/10.7554/elife.41913.036

المؤلفون: Philip A. Watson, Eugine Lee, Sawyers Charles L, Anuradha Gopalan, John Wongvipat, Ping Wang, Danielle Choi, Deyou Zheng

مصطلحات موضوعية: Gene knockdown, medicine.drug_class, Chemistry, Antiandrogen, medicine.disease, GREB1, Androgen receptor, Prostate cancer, chemistry.chemical_compound, Downregulation and upregulation, Coactivator, medicine, Cancer research, Enzalutamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f28667883e6cb07a232f5c62fdc019
https://doi.org/10.1101/433755

المؤلفون: Reese Howle, Danielle Choi, Selkirk Jk, Pierre R. Bushel, Kenneth J. Yost, Gerald J. Nehls, Qinyan Pan, Jennifer Fostel, Paul Boyer, Nancy Stegman, Cheng-Cheng Huang, Stanley Stasiewicz, Michael D. Waters, Denny D. Chan, Asif Rashid, John Taylor, Hui Gong, Kenneth B. Tomer, B. Alex Merrick, Richard S. Paules, Sandhya Xirasagar, Raymond W. Tennant, Nianqing Xiao, Ayazaddin Ahmed, Scott F. Gustafson, C. Harris Johnson

المصدر: Nucleic Acids Research

مصطلحات موضوعية: Genetics, Proteomics, Internet, Toxicity data, Relational database, Subject (documents), Computational biology, Articles, Information repository, Biology, Toxicogenetics, Rats, Chemical effects, Systems Integration, Mice, User-Computer Interface, Databases, Genetic, Animals, Humans, Toxicogenomics, Data selection, Oligonucleotide Array Sequence Analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4390e55e4f1eaf9d5d24abccd8dfde89
http://europepmc.org/articles/PMC2238989