المؤلفون: Jianqing Li (523126), Daniel Smith (6120), Joseph Pawluczyk (4435993), Subramaniam Krishnananthan (1402561), Bei Wang (116772), Xiaoping Hou (3225315), Rulin Zhao (1565887), James Kempson (1665415), Dawn Sun (1565869), Shiuhang Yip (1402564), Dauh-Rurng Wu (1402558), Nageswararao Maddala (6568862), Muthalagu Vetrichelvan (2518075), Anuradha Gupta (1551397), John E. Macor (1399363), Carolyn D. Dzierba (2493541), Arvind Mathur (144120)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Ecology, Inorganic Chemistry, Mental Health, Plant Biology, Chemical Sciences not elsewhere classified, treat neuropathic pain, oxy )‑ 5, original discovery route, yielding c –, 18 , 17 , c <, n <, h <, toxic reagents, substantial amount, quality material, preclinical studies, potent adaptor, parkinson ’, paper describes, key transformation

Relation: https://figshare.com/articles/journal_contribution/Development_of_a_Rapid_Scale-Up_Synthesis_of_i_S_i_i_N_i_8-_2-Amino-2_4-dimethylpentyl_oxy_5_i_H_i_chromeno_3_4_i_c_i_pyridin-2-yl_acetamide_a_Potent_Adaptor-Associated_Kinase_1_Inhibitor/19095285

الاتاحة: https://doi.org/10.1021/acs.oprd.1c00452.s001

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899920

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s001

المؤلفون: Andrew K. Dilger (2461681), Kumar B. Pabbisetty (1601845), James R. Corte (1705543), Indawati De Lucca (11407452), Tianan Fang (1705540), Wu Yang (414613), Donald J. P. Pinto (8212503), Yufeng Wang (274657), Yeheng Zhu (1870663), Arvind Mathur (144120), Jianqing Li (523126), Xiaoping Hou (3225315), Daniel Smith (6120), Dawn Sun (1565869), Huiping Zhang (135186), Subramaniam Krishnananthan (1402561), Dauh-Rurng Wu (1402558), Joseph E. Myers (2383984), Steven Sheriff (1601854), Karen A. Rossi (1601821), Silvi Chacko (10732002), Joanna J. Zheng (1601842), Michael A. Galella (2065051), Theresa Ziemba (10048686), Elizabeth A. Dierks (2443834), Jeffrey M. Bozarth (1601851), Yiming Wu (295996), Earl Crain (11407455), Pancras C. Wong (1601836), Joseph M. Luettgen (1550428), Ruth R. Wexler (1550446), William R. Ewing (1870717)

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Biotechnology, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, coagulation cascade thought, amplify thrombin generation, orally bioavailable inhibitor, milvexian , k <, , thromboembolic disorders, superior efficacy, solubility resulted, preclinical models, pk properties, oral administration, limited role, irreversible inhibitors, human genetics, free fraction, factor xia, clinical studies, clinical candidate, antithrombotic agent

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Milvexian_a_High-Affinity_Orally_Bioavailable_Inhibitor_of_Factor_XIa_in_Clinical_Studies_for_Antithrombotic_Therapy/16586658

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00613.s002

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_11_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913641

الاتاحة: https://doi.org/10.6084/m9.figshare.14913641.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_10_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913638

الاتاحة: https://doi.org/10.6084/m9.figshare.14913638.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_13_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913647

الاتاحة: https://doi.org/10.6084/m9.figshare.14913647.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913650

الاتاحة: https://doi.org/10.6084/m9.figshare.14913650.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_4_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913662

الاتاحة: https://doi.org/10.6084/m9.figshare.14913662.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_12_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913644

الاتاحة: https://doi.org/10.6084/m9.figshare.14913644.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_2_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913656

الاتاحة: https://doi.org/10.6084/m9.figshare.14913656.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_5_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913665

الاتاحة: https://doi.org/10.6084/m9.figshare.14913665.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_8_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913683

الاتاحة: https://doi.org/10.6084/m9.figshare.14913683.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_9_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913686

الاتاحة: https://doi.org/10.6084/m9.figshare.14913686.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_6_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913674

الاتاحة: https://doi.org/10.6084/m9.figshare.14913674.v1

المؤلفون: Lumbini Azim (11079761), Paul Hindmarch (11079764), Georgiana Browne (11079767), Thomas Chadwick (3468839), Emily Clare (11079770), Paul Courtney (11079773), Lyndsey Dixon (11079776), Nichola Duffelen (11079779), Tony Fouweather (708938), John R. Geddes (9118654), Nicola Goudie (3932057), Sandy Harvey (11079782), Timea Helter (11079785), Eva-Maria Holstein (226624), Garry Martin (11079788), Phil Mawson (11079791), Jenny McCaffery (11079794), Richard Morriss (11502), Judit Simon (4353796), Daniel Smith (6120), Paul R. A. Stokes (8731311), Jenn Walker (11079797), Chris Weetman (11079800), Faye Wolstenhulme (10516833), Allan H. Young (5677769), Stuart Watson (4527055), R. Hamish McAllister-Williams (11079803)

مصطلحات موضوعية: Neuroscience, Pharmacology, Biotechnology, Science Policy, Mental Health, Bipolar disorder, Treatment resistant bipolar depression, Pramipexole, Mood stabilisers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_7_of_Study_protocol_for_a_randomised_placebo-controlled_trial_of_pramipexole_in_addition_to_mood_stabilisers_for_patients_with_treatment_resistant_bipolar_depression_the_PAX-BD_study_/14913677

الاتاحة: https://doi.org/10.6084/m9.figshare.14913677.v1

المؤلفون: Daniel Smith (6120), Soon Hock Ng (1919953), Molong Han (9969314), Tomas Katkus (14408274), Vijayakumar Anand (4239631), Karl Glazebrook (14408277), Saulius Juodkazis (2012257)

مصطلحات موضوعية: Physics (arXiv), physics.optics (arXiv)

Relation: https://figshare.com/articles/preprint/Imaging_with_Diffractive_Axicons_Rapidly_Milled_on_Sapphire_by_Femtosecond_Laser_Ablation/21881847

الاتاحة: https://doi.org/10.48550/arxiv.2110.04113

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899923

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s002

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899926

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s003

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899929

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s004

المؤلفون: Peter T. W. Cheng (11620166), Robert F. Kaltenbach (2494921), Hao Zhang (15339), Jun Shi (289433), Shiwei Tao (2307016), Jun Li (6494), Lawrence J. Kennedy (2307007), Steven J. Walker (1780573), Yan Shi (166398), Ying Wang (11406), Suresh Dhanusu (11620169), Ramesh Reddigunta (11620172), Selvakumar Kumaravel (11620175), Sutjano Jusuf (1405201), Daniel Smith (6120), Subramaniam Krishnananthan (1402561), Jianqing Li (523126), Tao Wang (12008), Rebekah Heiry (11620178), Chi Shing Sum (2454928), Stephen S. Kalinowski (11620181), Chen-Pin Hung (1745170), Ching-Hsuen Chu (2950041), Anthony V. Azzara (1870696), Milinda Ziegler (11237235), Lisa Burns (397178), Bradley A. Zinker (2521423), Stephanie Boehm (1745227), Joseph Taylor (1730335), Julia Sapuppo (11620184), Kathy Mosure (1834165), Gerry Everlof (1601494), Victor Guarino (1601479), Lisa Zhang (339757), Yanou Yang (1432504), Qian Ruan (2141782), Carrie Xu (1711951), Atsu Apedo (2403871), Sarah C. Traeger (1622287), Mary Ellen Cvijic (1429885), Kimberley A. Lentz (2012935), Giridhar Tirucherai (1469497), Lakshmi Sivaraman (11620187), Jeffrey Robl (11620190), Bruce A. Ellsworth (1870660), Glenn Rosen (539561), David A. Gordon (278984), Matthew G. Soars (3827281), Michael Gill (195307), Brian J. Murphy (1870711)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, pulmonary fibrotic diseases, oxycyclohexyl acid bms, multiple preclinical species, excellent overall adme, 986020 (< b, 33 ,, 33 , 1 , b , 986278 (< b, k <, >< sub, vivo efficacy, studies starting, nct04308681 ), lung fibrosis, clinical trials, 9 nm

Relation: https://figshare.com/articles/dataset/Discovery_of_an_Oxycyclohexyl_Acid_Lysophosphatidic_Acid_Receptor_1_LPA_sub_1_sub_Antagonist_BMS-986278_for_the_Treatment_of_Pulmonary_Fibrotic_Diseases/16899932

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01256.s005