المؤلفون: Nicolas Chomont, Shih Lin Goh, Carolyn Bahnck-Teets, Paul Zuck, Bonnie J. Howell, Steven M. Lada, Amanda C Sciorillo, Douglas D. Richman, Mohammad Damra, Mohamed Abdel-Mohsen, Agnieszka Mackiewicz, Jay R. Kostman, Emmanouil Papasavvas, Amélie Pagliuzza, Pablo Tebas, Kwasi Gyampoh, Matthew Fair, Kenneth Lynn, Zhe Yuan, Karam Mounzer, Livio Azzoni, Guoxin Wu, Brian N Ross, Luis J. Montaner, Daniel J. Holder

المصدر: Clin Infect Dis

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, Microbiology (medical), viruses, Human immunodeficiency virus (HIV), HIV Infections, Proviral dna, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Proviruses, Humans, Medicine, business.industry, virus diseases, Provirus, Antiretroviral therapy, Virology, Virus Latency, 030104 developmental biology, Infectious Diseases, chemistry, DNA, Viral, HIV-1, Brief Reports, business, 030217 neurology & neurosurgery, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9dac788321df38f3df5e7faf27e9ea5
https://doi.org/10.1093/cid/ciaa809

المؤلفون: Thomas R. Skopek, Warren E. Glaab, Laura Michna, Carolann Beare, Wendy J. Bailey, Frank D. Sistare, Daniel J. Holder, Nagaraja Muniappa, David Gerhold, Joseph F. Sina, Yudong D He, Jeffrey W. Lawrence, Zoltan Erdos, Pamela Lane, Keith Q. Tanis

المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 181(2)

مصطلحات موضوعية: Gastrointestinal tract, Pathology, medicine.medical_specialty, Kidney, Urinary bladder, Gene Expression Profiling, Skeletal muscle, Toxicology, Risk Assessment, Rats, Tissue Degeneration, Real-time polymerase chain reaction, medicine.anatomical_structure, Liver, Pharmaceutical Preparations, medicine, Biomarker (medicine), Animals, Pancreas, Transcriptome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d035f511764e56dbc4c0a33dd1ef1df
https://pubmed.ncbi.nlm.nih.gov/33837425

المؤلفون: Yingxue C. Liu, Adam T. Gates, Priya Kunapuli, Erica M. Stec, Min Xu, Shane D. Marine, Daniel J. Holder, Berta Strulovici, Joseph F. Heyse, Amy S. Espeseth

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://nar.oxfordjournals.org/content/early/2008/07/15/nar.gkn435.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.605.179; http://nar.oxfordjournals.org/content/early/2008/07/15/nar.gkn435.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.605.179
http://nar.oxfordjournals.org/content/early/2008/07/15/nar.gkn435.full.pdf

المؤلفون: Xiaohua Douglas Zhang, Pei Fen Kuan, Marc Ferrer, Xiaohua Shu, Yingxue C. Liu, Adam T. Gates, Priya Kunapuli, Erica M. Stec, Min Xu, Shane D. Marine, Daniel J. Holder, Berta Strulovici, Joseph F. Heyse, Amy S. Espeseth

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/69/a1/Nucleic_Acids_Res_2008_Aug_36(14)_4667-4679.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.11

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.11

المؤلفون: Ying Jiang, David L Gerhold, Daniel J Holder, David J Figueroa, Wendy J Bailey, Ping Guan, Thomas R Skopek, Frank D Sistare

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/89/8b/J_Transl_Med_2007_Oct_1_5_47.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.282.495

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.282.495

المؤلفون: Cyrille Sur, Daniel J. Holder, Eric M. Parker, Marie Sondey, Lynn A. Hyde, Fuqiang Zhao, Thomas Forest, Xia Chen, Stephanie Villarreal, Matthew E. Kennedy

المصدر: Journal of Alzheimer's Disease

مصطلحات موضوعية: 0301 basic medicine, Pathology, Hippocampus, Plaque, Amyloid, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Cerebrospinal fluid, Medicine, Longitudinal Studies, microhemorrhage, biology, Thiadiazines, General Neuroscience, disease modification, General Medicine, Magnetic Resonance Imaging, Cyclic S-Oxides, inhibitor, Psychiatry and Mental health, Clinical Psychology, Enzyme inhibitor, Immunohistochemistry, Antibody, Alzheimer’s disease, Intracranial Hemorrhages, medicine.drug, Research Article, MRI, Antipsychotic Agents, Collagen Type IV, medicine.medical_specialty, animal structures, Amyloid, Mice, Transgenic, beta-secretase, amyloid-β, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, Alzheimer Disease, Presenilin-1, Animals, Humans, Bapineuzumab, BACE, ARIA, Amyloid beta-Peptides, business.industry, prodromal Alzheimer’s disease, Disease Models, Animal, 030104 developmental biology, Mutation, biology.protein, Verubecestat, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485e311dc5d44823c59f831cd3f0fb05
http://europepmc.org/articles/PMC5611839

المؤلفون: José A. Lebrón, Donna Lynch, Kristin Geddes, Stephen Pacchione, Hong Duong, Yutai Li, Warren E. Glaab, Alema Galijatovic-Idrizbegovic, Frank D. Sistare, Wen Kang, Raymond J. Gonzalez, Daniel J. Holder, Kyeongmi Cheon, Kara Pearson, Nanyan Rena Zhang, Alex M Tamburino, Michael J. Hafey, Raymond Evers, Keith Q. Tanis, Lisa LaFranco-Scheuch

المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 170(1)

مصطلحات موضوعية: 0301 basic medicine, Male, Taurine, Bilirubin, medicine.drug_class, Glycocholic acid, Pharmacology, Toxicology, Taurochenodeoxycholic Acid, 03 medical and health sciences, Benzbromarone, chemistry.chemical_compound, 0302 clinical medicine, medicine, Animals, RNA, Small Interfering, Rats, Wistar, ATP Binding Cassette Transporter, Subfamily B, Member 11, Transaminases, Liver injury, Bile acid, medicine.disease, Bile Salt Export Pump, Acetaminophen, Rats, Disease Models, Animal, 030104 developmental biology, chemistry, Pharmaceutical Preparations, Gene Knockdown Techniques, Chemical and Drug Induced Liver Injury, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0bf4d9d28084bd888d7572b62cf84e
https://pubmed.ncbi.nlm.nih.gov/30903168

المؤلفون: Philip Scheltens, Christy Weiss, Jackie Surls, Arie Struyk, Cyrille Sur, Kimberly Wilson, Julie Stromswold, Mary J. Savage, Johan Luthman, Stephanie R. Rainey-Smith, David Darby, Sigrid Botne Sando, Omar F Laterza, James R. Burke, Arturo Cowes, Linda R. White, Geir Bråthen, Eileen Sagini, Michael Tanen, Michele M. Bush, Amy Altman, Charlotte E. Teunissen, Michael F. Egan, Yi Mo, Ganga DeSilva, Daniel J. Holder, S. Lance Macaulay

المساهمون: Neurology, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation, Clinical chemistry, CCA - Imaging and biomarkers

المصدر: Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 6, 201-209. Elsevier BV
Mo, Y, Stromswold, J, Wilson, K, Holder, D, Sur, C, Laterza, O, Savage, M J, Struyk, A, Scheltens, P, Teunissen, C E, Burke, J, Macaulay, S L, Bråthen, G, Sando, S B, White, L R, Weiss, C, Cowes, A, Bush, M M, DeSilva, G, Darby, D G, Rainey-Smith, S R, Surls, J, Sagini, E, Tanen, M, Altman, A, Luthman, J & Egan, M F 2017, ' A multinational study distinguishing Alzheimer's and healthy patients using cerebrospinal fluid tau/Aβ42 cutoff with concordance to amyloid positron emission tomography imaging ', Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, vol. 6, pp. 201-209 . https://doi.org/10.1016/j.dadm.2017.02.004

مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Amyloid, Concordance, Population, CSF Biomarkers, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, mental disorders, medicine, Cutoff, education, education.field_of_study, medicine.diagnostic_test, Amyloidosis, Alzheimer's disease, medicine.disease, Amyloid β42, Psychiatry and Mental health, 030104 developmental biology, PET, Positron emission tomography, Csf analysis, Neurology (clinical), Tau, Psychology, Diagnostic test assessment, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a792222e20f52a57882ee0f0083a2b
https://doi.org/10.1016/j.dadm.2017.02.004

المؤلفون: Daniel J. Holder, Guro Berge, Camilla Lauridsen, Linda R. White, Geir Bråthen, Ina Møller, Mary J. Savage, Jan O. Aasly, Sigrid Botne Sando

المصدر: Journal of Alzheimer's Disease. 49:493-502

مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, Tau protein, Polysorbates, Enzyme-Linked Immunosorbent Assay, tau Proteins, Disease, Gastroenterology, Surface-Active Agents, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, medicine, Humans, Dementia, Cognitive Dysfunction, Centrifugation, Longitudinal Studies, Phosphorylation, Cognitive impairment, Aged, Core (anatomy), Amyloid beta-Peptides, biology, business.industry, General Neuroscience, General Medicine, Middle Aged, equipment and supplies, medicine.disease, Peptide Fragments, Psychiatry and Mental health, Clinical Psychology, ROC Curve, biology.protein, Female, Geriatrics and Gerontology, Alzheimer's disease, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb15c46e141afe7ac025dfc7eae5b26
https://doi.org/10.3233/jad-150234

المؤلفون: Daniel J. Holder, Jeffrey L. Seeburger, C Joachim, Mary J. Savage, A. David Smith, Marc Combrinck, Vijay Modur, Karen Snyder, William Z. Potter, Michael Tanen, Derek L Chappell, Adam J. Simon, Omar F Laterza, Mary Flynn, Gordon K. Wilcock, Aimee Dallob

المصدر: Journal of Alzheimer's Disease. 44:525-539

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Population, tau Proteins, Disease, Sensitivity and Specificity, Gastroenterology, Amyloid beta-Protein Precursor, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, mental disorders, medicine, Humans, Dementia, Cognitive Dysfunction, Longitudinal Studies, Phosphorylation, education, Aged, Aged, 80 and over, education.field_of_study, Amyloid beta-Peptides, business.industry, General Neuroscience, General Medicine, Middle Aged, medicine.disease, Peptide Fragments, Psychiatry and Mental health, Clinical Psychology, CTL, Cohort, Biomarker (medicine), Geriatrics and Gerontology, business, Biomarkers, Follow-Up Studies, Frontotemporal dementia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11086d3820f96774e32cc9a2d0e48c1
https://doi.org/10.3233/jad-141725

المؤلفون: Michael J. Marino, Daniel J. Holder

المصدر: Current protocols in pharmacologyLiterature Cited. 76

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Focus (computing), Blinding, Variables, Biomedical Research, Computer science, media_common.quotation_subject, Reproducibility of Results, Pilot Projects, General Medicine, Data science, Causality, 03 medical and health sciences, Power analysis, Logical framework, Disease Models, Animal, 030104 developmental biology, Sample size determination, Research Design, Mill, Animals, Humans, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c0ec12c47cc61e5e7edf30327dcd8b
https://pubmed.ncbi.nlm.nih.gov/28306153

المؤلفون: Guoxin Wu, Kristin R. Wildsmith, Andrew Stamford, Kevin E. Yarasheski, Matthew E. Kennedy, David B. Gilberto, Yuriy Pyatkivskyy, Randall J. Bateman, Daniel J. Holder, Mary J. Savage, Robert Chott, Debra A. McLoughlin, Justyna Dobrowolska, Bruce W. Patterson, Mandy Dancho, Tom Kasten, Vitaliy Ovod, Parker Mathers, Maria S. Michener, Christina Lennox, Brad E. Smith

المصدر: Journal of Neuroscience. 34:8336-8346

مصطلحات موضوعية: Central Nervous System, Amyloid beta, Immunoprecipitation, Central nervous system, Pharmacology, Transfection, Mass Spectrometry, Amyloid beta-Protein Precursor, Neuroblastoma, Leucine, Cell Line, Tumor, medicine, Amyloid precursor protein, Animals, Humans, Enzyme Inhibitors, Carbon Isotopes, Amyloid beta-Peptides, Cross-Over Studies, Dose-Response Relationship, Drug, biology, Chemistry, General Neuroscience, Articles, medicine.disease, Macaca mulatta, Peptide Fragments, medicine.anatomical_structure, Biochemistry, biology.protein, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8226a5d06346bb6b6f0282836004a342
https://doi.org/10.1523/jneurosci.0540-14.2014

المؤلفون: Daniel J. Holder, Clay B. Frederick, Adam Smith, Caron L. Cunningham, Xiaorui Yao, Srinivasa Prahalada, Markus Dey, Thomas Forest

المصدر: Endocrinology. 155:783-792

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, endocrine system diseases, Administration, Oral, Incretin, Diabetes Mellitus, Experimental, Endocrinology, Diabetes mellitus, Internal medicine, medicine, Animals, Hypoglycemic Agents, Dosing, Cell Proliferation, business.industry, Body Weight, Sitagliptin Phosphate, nutritional and metabolic diseases, Type 2 Diabetes Mellitus, Triazoles, medicine.disease, Glucagon-like peptide-1, Metformin, Pancreas, Exocrine, Rats, Rats, Zucker, Disease Models, Animal, Ki-67 Antigen, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Pyrazines, Sitagliptin, Keratins, Pancreas, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb38b29a3d81601998cfc200fa55fef4
https://doi.org/10.1210/en.2013-1781

المؤلفون: Nathalie Mokrzycki, Wendy J. Bailey, Frank D. Sistare, Kathleen A. McNulty, Nagaraja Muniappa, Valérie Chapeau-Campredon, Daniel J. Holder, Yi-Zhong Gu, Zoltan Erdos, Katerina Vlasakova, Warren E. Glaab, Sean P. Troth

المصدر: Toxicological Sciences. 138:3-20

مصطلحات موضوعية: Male, medicine.medical_specialty, Urinary system, Urology, Renal function, Enzyme-Linked Immunosorbent Assay, Kidney, Toxicology, Rats, Sprague-Dawley, chemistry.chemical_compound, Limit of Detection, Internal medicine, Toxicity Tests, medicine, Animals, Rats, Wistar, Blood urea nitrogen, Creatinine, biology, Clusterin, urogenital system, Rats, Endocrinology, medicine.anatomical_structure, ROC Curve, chemistry, Cystatin C, biology.protein, Biomarker (medicine), Female, Kidney Diseases, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd7e80c6de1d879bf2955c3216ecaf6
https://doi.org/10.1093/toxsci/kft330

المؤلفون: Frank D. Sistare, Daniel J. Holder, Michael J. Hafey, Alema Galijatovic-Idrizbegovic, Raymond Evers, Hong Duong, Yutai Li, Kyeongmi Cheon, Warren E. Glaab

المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 157(1)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.drug_class, Bilirubin, Antibiotics, Pharmacology, Toxicology, Bile Acids and Salts, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Tandem Mass Spectrometry, medicine, Animals, Rats, Wistar, ATP Binding Cassette Transporter, Subfamily B, Member 11, Liver injury, Bile acid, Chemistry, Transporter, medicine.disease, Taurocholic acid, Bile Salt Export Pump, Anti-Bacterial Agents, Rats, 030104 developmental biology, Toxicity, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbad0719e701b3aac0920e55234922ba
https://pubmed.ncbi.nlm.nih.gov/28108666

المؤلفون: Jonathan A. Phillips, Peter M. Burch, Warren E. Glaab, Daniel J. Holder, John-Michael Sauer, Elizabeth G. Walker

المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 156(1)

مصطلحات موضوعية: 0301 basic medicine, Index (economics), Drug-Related Side Effects and Adverse Reactions, Computer science, Organizations, Nonprofit, Drug Evaluation, Preclinical, Toxicology, Xenobiotics, Forum: Method Evaluation for Predictive Biomarkers, 03 medical and health sciences, 0302 clinical medicine, Muscular Diseases, Predictive Value of Tests, Statistics, Significance testing, Toxicity Tests, Animals, Humans, False Positive Reactions, Renal Insufficiency, Safety testing, Models, Statistical, Drugs, Investigational, Predictive value, United States, Net reclassification improvement, 030104 developmental biology, ROC Curve, 030220 oncology & carcinogenesis, Biomarker (medicine), Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95393e798f04b29d556d5b9a07b2fad
https://pubmed.ncbi.nlm.nih.gov/27815493

المؤلفون: Elizabeth G. Walker, Daniela Ennulat, Diane Hamlin, Yi Yang, Karen M. Lynch, Manisha Sonee, Sean P. Troth, Dominique Brees, John-Michael Sauer, Jonathan A. Phillips, Jean-Charles Gautier, David Peters, Yi-Zhong Gu, J. Eric McDuffie, Daniel J. Holder

المصدر: Toxicological sciences : an official journal of the Society of Toxicology. 151(2)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pathology, Urinary system, 030232 urology & nephrology, Urology, Lipocalin, Biology, Urinalysis, Toxicology, Nephrotoxicity, Blood Urea Nitrogen, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, stomatognathic system, Lipocalin-2, Predictive Value of Tests, Proto-Oncogene Proteins, medicine, Animals, Blood urea nitrogen, Creatinine, Kidney, Clusterin, Acute kidney injury, Reproducibility of Results, Acute Kidney Injury, medicine.disease, Lipocalins, Rats, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, chemistry, ROC Curve, Area Under Curve, biology.protein, Osteopontin, Biomarkers, Acute-Phase Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5324942cbd924efcbe077cb0ea1cc24c
https://pubmed.ncbi.nlm.nih.gov/27026710

المؤلفون: Robin Mogg, Daniel J. Holder

المصدر: Drug Discovery Toxicology

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Drug induced toxicity, Renal injury, Computer science, Internal medicine, medicine, Biomarker (medicine)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::448a17de735fb4659e6ef6bfe8241479
https://doi.org/10.1002/9781119053248.ch43

المؤلفون: Daniel J. Holder, Peter Lischka, Holger Zimmermann, Douglas Zhang

المصدر: Antiviral research. 132

مصطلحات موضوعية: 0301 basic medicine, Human cytomegalovirus, Genotype, 030106 microbiology, Viral terminase complex, Cytomegalovirus, Drug resistance, Microbial Sensitivity Tests, Acetates, medicine.disease_cause, Antiviral Agents, Polymorphism, Single Nucleotide, Pathogenesis, 03 medical and health sciences, Letermovir, Viral Envelope Proteins, Polymorphism (computer science), Virology, Drug Resistance, Viral, Medicine, Humans, Ganciclovir, Pharmacology, Viral Structural Proteins, Mutation, Polymorphism, Genetic, business.industry, medicine.disease, Cytomegalovirus Infections, Quinazolines, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec66a679558dcf4571fbe8e846ce3215
https://pubmed.ncbi.nlm.nih.gov/27345658

المؤلفون: Luca Benetti, Raul Lacson, Joseph F. Heyse, Shane D. Marine, Erica Stec, Xiaohua Douglas Zhang, Joel P. Berger, Keith A. Soper, Daniel J. Holder, Dawn Toolan, Marc Ferrer, Ruojing Yang, Qian Wu, Alex McCampbell, Francesca Santini

المصدر: Bioinformatics. 27:2775-2781

مصطلحات موضوعية: Statistics and Probability, Herpesvirus 3, Human, Small interfering RNA, Genome scale, Genomics, Computational biology, Biology, Biochemistry, Alzheimer Disease, RNA interference, High-Throughput Screening Assays, Diabetes Mellitus, Gene Knockdown Techniques, False positive paradox, Humans, RNA, Small Interfering, Molecular Biology, Gene, Genetics, Original Papers, Computer Science Applications, Computational Mathematics, Computational Theory and Mathematics, Data Interpretation, Statistical, RNA Interference

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a90f4cb27c8d63fd704a9631254820
https://doi.org/10.1093/bioinformatics/btr474