المؤلفون: Benedito Roberto de Alvarenga (11841270), Dana E. Moseson (6654068), Renato Lajarim Carneiro (3225795), Lynne S. Taylor (1349709)

مصطلحات موضوعية: Biophysics, Medicine, Microbiology, Pharmacology, Biotechnology, Inorganic Chemistry, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, vinyl acetate copolymer, poly ­( vinylpyrrolidone, hot melt extrusion, following isothermal heating, amorphous solid dispersions, reduced degradation rates, dominant degradation product, accelerated degradation rates, lc – ms, reaction series led, dehydration reaction, thermal degradation, degradation products, understanding mechanisms, underlying mechanisms, thermal stability, temperature exposure, protic polymers, poorly understood, polymer type

Relation: https://figshare.com/articles/journal_contribution/Impact_of_Polymer_Type_on_Thermal_Degradation_of_Amorphous_Solid_Dispersions_Containing_Ritonavir/17209167

الاتاحة: https://doi.org/10.1021/acs.molpharmaceut.1c00823.s001

المؤلفون: Dana E. Moseson (6654068), Ayse Eren (11841828), Kevin J. Altman (11841831), Isaac D. Corum (11841834), Mingyue Li (1582399), Yongchao Su (1317195), Zoltan K. Nagy (1515985), Lynne S. Taylor (1349709)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Biotechnology, Ecology, Infectious Diseases, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, improved process modeling, hot melt extrusion, incorporating particle attributes, crystal size distribution, crystal dissolution process, particle engineering approaches, melting point requires, high defect density, experimental hme results, crystal dissolution, particle size, particle engineering, defect density, synergistically accelerated, recrystallize bicalutamide, parameter estimation, molten polymer, expected effect, dynamic evolution, drug ’

Relation: https://figshare.com/articles/journal_contribution/Optimization_of_Amorphization_Kinetics_during_Hot_Melt_Extrusion_by_Particle_Engineering_An_Experimental_and_Computational_Study/17209581

الاتاحة: https://doi.org/10.1021/acs.cgd.1c01306.s001

المؤلفون: Ahmed Elkhabaz (7865060), Dana E. Moseson (6654068), Sreya Sarkar (1342182), Joachim Brouwers (114594), Garth J. Simpson (589685), Patrick Augustijns (114600), Lynne S. Taylor (1349709)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Physiology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, crystallization kinetics, supersaturated solutions, Aspirated Human Intestinal Fluids, fluid, phase behavior, media

Relation: https://figshare.com/articles/journal_contribution/Crystallization_Kinetics_in_Fasted-State_Simulated_and_Aspirated_Human_Intestinal_Fluids/14383485

الاتاحة: https://doi.org/10.1021/acs.cgd.0c01730.s001

المؤلفون: Venecia R. Wilson (10099603), Naila A. Mugheirbi (2832227), Laura I. Mosquera-Giraldo (1495771), Alexandru Deac (6244373), Dana E. Moseson (6654068), Daniel T. Smith (547304), Diana C. Novo (10099606), Carlos H. Borca (3202962), Lyudmila V. Slipchenko (1281621), Kevin J. Edgar (1495768), Lynne S. Taylor (1349709)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Pharmacology, Cancer, Mental Health, Hematology, Virology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, polymer, Certain ASD formulations, supersaturated solutions, crystallization, Eudragit E PO, drug-rich nanodroplets, Induction Times Amorphous, HPMCAS, drug nanodroplets, hydroxypropylmethyl cellulose aceta., nucleation induction times

Relation: https://figshare.com/articles/journal_contribution/Interaction_of_Polymers_with_Enzalutamide_Nanodroplets_Impact_on_Droplet_Properties_and_Induction_Times/13717906

الاتاحة: https://doi.org/10.1021/acs.molpharmaceut.0c00833.s001