المؤلفون: Luka Rejc, Damijan Knez, Gabriela Molina-Aguirre, Alba Espargaró, Jerneja Kladnik, Anže Meden, Lana Blinc, Matic Lozinšek, Ross D. Jansen-van Vuuren, Matic Rogan, Bruno Aleksander Martek, Jernej Mlakar, Ana Dremelj, Andrej Petrič, Stanislav Gobec, Raimon Sabaté, Mara Bresjanac, Balazs Pinter, Janez Košmrlj

المصدر: Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116616- (2024)

مصطلحات موضوعية: Alzheimer’s disease, Amyloid β, Fluorophore, Solvatochromism, Synthesis, Photophysics, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332224005006; https://doaj.org/toc/0753-3322; https://doaj.org/article/5dba3452cc3d4596945a7835ff379451

الاتاحة: https://doi.org/10.1016/j.biopha.2024.116616
https://doaj.org/article/5dba3452cc3d4596945a7835ff379451

المؤلفون: Damijan Knez, Daniel Diez-Iriepa, Mourad Chioua, Andrea Gottinger, Milica Denic, Fabien Chantegreil, Florian Nachon, Xavier Brazzolotto, Anna Skrzypczak-Wiercioch, Anže Meden, Anja Pišlar, Janko Kos, Simon Žakelj, Jure Stojan, Kinga Sałat, Julia Serrano, Ana Patricia Fernández, Aitana Sánchez-García, Ricardo Martínez-Murillo, Claudia Binda, Francisco López-Muñoz, Stanislav Gobec, José Marco-Contelles

المصدر: Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 2152-2175 (2023)

مصطلحات موضوعية: Quinolylnitrone, Butyrylcholinesterase, Monoamine oxidase B, Alzheimer's disease, Multifunctional ligands, 6-Hydroxydopamine model, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383523000138; https://doaj.org/toc/2211-3835

URL الوصول: https://doaj.org/article/7f16c8ed45a64b12942b299889a26612

المؤلفون: Lana Blinc, Mateja Drolec Novak, Jernej Mlakar, Damijan Knez, Matic Rogan, Jerneja Kladnik, Ross Jansen-Van Vuuren, Janez Košmrlj, Maja Bresjanac

المصدر: IBRO Neuroscience Reports, Vol 15, Iss , Pp S371- (2023)

مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667242123007649; https://doaj.org/toc/2667-2421

URL الوصول: https://doaj.org/article/b88cf8f835b64d8bb4ec89d393ddcc3c

المؤلفون: Carolina Marcucci, Marina Rademacher, Fabiola Kamecki, Valentina Pastore, Hernán Gerónimo Bach, Rafael Alejandro Ricco, Marcelo Luis Wagner, Damijan Knez, Stanislav Gobec, Natalia Colettis, Mariel Marder

المصدر: Pharmaceuticals; Volume 16; Issue 1; Pages: 129

مصطلحات موضوعية: Alzheimer’s disease, medicinal plant, acetylcholinesterase, antioxidant, β-amyloid aggregation, monoamine oxidase, memory, antidepressant

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/ph16010129

الاتاحة: https://doi.org/10.3390/ph16010129

المؤلفون: Péter Ábrányi-Balogh, Aaron Keeley, György G. Ferenczy, László Petri, Tímea Imre, Katarina Grabrijan, Martina Hrast, Damijan Knez, Janez Ilaš, Stanislav Gobec, György M. Keserű

المصدر: Pharmaceuticals; Volume 15; Issue 12; Pages: 1484

مصطلحات موضوعية: covalent inhibitor, heterocyclic electrophiles, cysteine labelling, quaternization, MurA

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/ph15121484

الاتاحة: https://doi.org/10.3390/ph15121484

المؤلفون: Óscar M. Bautista-Aguilera, José M. Alonso, Marco Catto, Isabel Iriepa, Damijan Knez, Stanislav Gobec, José Marco-Contelles

المصدر: Molecules; Volume 27; Issue 21; Pages: 7437

مصطلحات موضوعية: cholinesterases, ferulic acid, molecular modelling, monoamine oxidase, radical-scavenger, antioxidant

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules27217437

الاتاحة: https://doi.org/10.3390/molecules27217437

المؤلفون: Daniel Diez-Iriepa, Damijan Knez, Stanislav Gobec, Isabel Iriepa, Cristóbal de los Ríos, Isaac Bravo, Francisco López-Muñoz, José Marco-Contelles, Dimitra Hadjipavlou-Litina

المصدر: Antioxidants; Volume 11; Issue 9; Pages: 1735

مصطلحات موضوعية: antioxidants, butyrylcholinesterase, free radical scavengers, neuroprotection, α-phenyl-tert-butyl(benzyl)nitrones

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Health Outcomes of Antioxidants and Oxidative Stress; https://dx.doi.org/10.3390/antiox11091735

الاتاحة: https://doi.org/10.3390/antiox11091735

المؤلفون: Damijan Knez, Stanislav Gobec, Martina Hrast

المصدر: Molecules; Volume 27; Issue 14; Pages: 4484

مصطلحات موضوعية: Merck Mini Library, screening, MurA, MurC, human MAO-A/B, human BChE, murine AchE

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules27144484

الاتاحة: https://doi.org/10.3390/molecules27144484

المؤلفون: Bernarda Majc, Anamarija Habič, Metka Novak, Ana Rotter, Andrej Porčnik, Jernej Mlakar, Vera Župunski, Urša Pečar Pečar Fonović, Damijan Knez, Nace Zidar, Stanislav Gobec, Janko Kos, Tamara Lah Lah Turnšek, Anja Pišlar, Barbara Breznik

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1784

مصطلحات موضوعية: glioblastoma, cathepsin X, γ-enolase, tumor microenvironment, glioblastoma stem cells, cathepsin X inhibitors

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms23031784

الاتاحة: https://doi.org/10.3390/ijms23031784

المؤلفون: Sandra Cetin, Damijan Knez, Stanislav Gobec, Janko Kos, Anja Pišlar

المصدر: Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112924- (2022)

مصطلحات موضوعية: Neurodegenerative diseases, Cell models, Cytotoxicity assays, Drug discovery, Drug screening, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332222003134; https://doaj.org/toc/0753-3322; https://doaj.org/article/98c47b3d773b46e5b4de77055bb3c243

الاتاحة: https://doi.org/10.1016/j.biopha.2022.112924
https://doaj.org/article/98c47b3d773b46e5b4de77055bb3c243

المؤلفون: Stane Pajk, Damijan Knez, Urban Košak, Maja Zorović, Xavier Brazzolotto, Nicolas Coquelle, Florian Nachon, Jacques-Philippe Colletier, Marko Živin, Jure Stojan, Stanislav Gobec

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 498-505 (2020)

مصطلحات موضوعية: butyrylcholinesterase, inhibitor, probe, fluorescence, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/dbf12d5fe8ba43da9d6b77ed1a105af9

المؤلفون: Levente Kollár, Martina Gobec, Matic Proj, Lara Smrdel, Damijan Knez, Tímea Imre, Ágnes Gömöry, László Petri, Péter Ábrányi-Balogh, Dorottya Csányi, György G. Ferenczy, Stanislav Gobec, Izidor Sosič, György M. Keserű

المصدر: Cells; Volume 10; Issue 12; Pages: 3431

مصطلحات موضوعية: immunoproteasome, benzoxazole-2-carbonitriles, bidentate covalent inhibitors, fragments, non-covalent recognition

وصف الملف: application/pdf

Relation: Cellular Immunology; https://dx.doi.org/10.3390/cells10123431

الاتاحة: https://doi.org/10.3390/cells10123431

المؤلفون: Tjaša Mazej, Damijan Knez, Anže Meden, Stanislav Gobec, Matej Sova

المصدر: Molecules; Volume 26; Issue 14; Pages: 4118

مصطلحات موضوعية: Alzheimer’s disease, butyrylcholinesterase, monoamine oxidase B, inhibitors, multi-target-directed ligands, multifunctional ligands

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules26144118

الاتاحة: https://doi.org/10.3390/molecules26144118

المؤلفون: Dawid Panek, Anna Więckowska, Anna Pasieka, Justyna Godyń, Jakub Jończyk, Marek Bajda, Damijan Knez, Stanislav Gobec, Barbara Malawska

المصدر: Molecules; Volume 23; Issue 2; Pages: 347

مصطلحات موضوعية: isoindoline-1,3-dione derivatives, cholinesterase inhibitors, BACE-1 inhibitors, Aβ-aggregation, molecular modeling, multiple anti-Alzheimer’s ligands

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Bioorganic Chemistry; https://dx.doi.org/10.3390/molecules23020347

الاتاحة: https://doi.org/10.3390/molecules23020347

المؤلفون: Anže Meden, Damijan Knez, Xavier Brazzolotto, Fabrice Modeste, Andrej Perdih, Anja Pišlar, Maša Zorman, Maja Zorović, Milica Denic, Stane Pajk, Marko Živin, Florian Nachon, Stanislav Gobec

المصدر: European journal of medicinal chemistry. 247

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d593c4357e4e1d752379a2c2350596d0
https://pubmed.ncbi.nlm.nih.gov/36586299

المؤلفون: Anže Meden, Damijan Knez, Xavier Brazzolotto, Fabrice Modeste, Andrej Perdih, Anja Pišlar, Maša Zorman, Milica Denic, Stane Pajk, Florian Nachon, Stanislav Gobec

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e36bafe2a0d348c1e3f308659b9027e8
https://doi.org/10.26434/chemrxiv-2022-msbb4-v2

المؤلفون: Matic Proj, Martina Hrast, Damijan Knez, Krištof Bozovičar, Katarina Grabrijan, Anže Meden, Stanislav Gobec, Rok Frlan

المصدر: ACS medicinal chemistry letters. 13(12)

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094b30a68a94ec61d5f50c5b3094f8d4
https://pubmed.ncbi.nlm.nih.gov/36518695

المؤلفون: Anže Meden, Damijan Knez, Xavier Brazzolotto, Fabrice Modeste, Andrej Perdih, Anja Pišlar, Maša Zorman, Milica Denic, Stane Pajk, Florian Nachon, Stanislav Gobec

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2bef53dc2d374b13838c58cef51aa720
https://doi.org/10.26434/chemrxiv-2022-msbb4

المؤلفون: György M. Keserű, László Petri, Tímea Imre, Damijan Knez, Andrea Scarpino, György G. Ferenczy, Stanislav Gobec, Péter Ábrányi-Balogh

المصدر: Journal of Computer-Aided Molecular Design

مصطلحات موضوعية: Virtual screening, Protein Conformation, Covalent docking, Ligands, 01 natural sciences, Article, Covalent inhibitors, Cathepsin B, Proto-Oncogene Proteins p21(ras), Structure-Activity Relationship, 03 medical and health sciences, Mura, Docking (dog), Drug Discovery, Reactivity (chemistry), Amino Acid Sequence, Cysteine, Enzyme Inhibitors, Physical and Theoretical Chemistry, Protocol (object-oriented programming), 030304 developmental biology, 0303 health sciences, Alkyl and Aryl Transferases, Binding Sites, 010405 organic chemistry, Chemistry, Warhead reactivity, Ligand (biochemistry), Glutathione, Combinatorial chemistry, 0104 chemical sciences, Computer Science Applications, Molecular Docking Simulation, Covalent bond, Electrophile, Software, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484f01969048dce96db56c0dca851922
https://doi.org/10.1007/s10822-020-00371-5

المؤلفون: András Perczel, Luca Giacinto Iacovino, Stanislav Gobec, Imre Tímea, Simona Golic Grdadolnik, Iza Ogris, Niklas Jänsch, Franz-Josef Meyer-Almes, László Petri, Damijan Knez, Martina Hrast, Izidor Sosič, György M. Keserű, Martina Gobec, Claudia Binda, Charlotte Desczyk, Gyula Pálfy, Péter Ábrányi-Balogh, Kinga Nyíri, Beáta G. Vértessy

المصدر: ChemBioChem. 22:743-753

مصطلحات موضوعية: Proteome, Chemical biology, 010402 general chemistry, 01 natural sciences, Biochemistry, Nucleophile, Drug Discovery, Humans, Reactivity (chemistry), Cysteine, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Alkyl and Aryl Transferases, 010405 organic chemistry, Drug discovery, Chemistry, Organic Chemistry, Combinatorial chemistry, High-Throughput Screening Assays, 0104 chemical sciences, Amino acid, Covalent bond, Electrophile, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e176d621cf73d7044a3c776debd5f29e
https://doi.org/10.1002/cbic.202000700