المؤلفون: Eirefelt, Stefan, Stahlhut, Martin, Svitacheva, Naila, Carnerup, Martin A., Da Rosa, Joel Mauricio Correa, Ewald, David Adrian, Marstrand, Troels T., Krogh-Madsen, Mikkel, Dünstl, Georg, Dack, Kevin Neil, Ollerstam, Anna, Norsgaard, Hanne

المصدر: Scientific Reports ; volume 12, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-022-05471-w
https://www.nature.com/articles/s41598-022-05471-w.pdf
https://www.nature.com/articles/s41598-022-05471-w

المؤلفون: Andrews, Mark David, de Groot, Marcel John, Dack, Kevin Neil

المصدر: Medicinal Chemistry Reviews ; 2022 Medicinal Chemistry Reviews ; page 221-238 ; ISSN 2575-9183 2575-9175 ; ISBN 9781734427455 9781734427455

الاتاحة: http://dx.doi.org/10.1021/mc-2022-vol57.ch09
https://pubs.acs.org/doi/pdf/10.1021/mc-2022-vol57.ch09

المؤلفون: Ivaylo Jivkov Elenkov, Simon Feldbaek Nielsen, Kristina Butković, Sanja Koštrun, Dijana Pesic, Dack Kevin Neil, Tine Skak-Nielsen, Dinko Žiher, Martin Stahlhut, Adriana Petrinić Grba, Vlatka Bencetić Mihaljević, Ana Čikoš, Samra Kapić, Andrea Fajdetić, Renata Rupčić, Gordon Saxty, Maja Lambert, Jasna Padovan, Ivana Ozimec Landek, Karmen Brajša, Dubravko Jelić, Haakan Bladh, Ana Grgičević

المصدر: Journal of Medicinal Chemistry. 64:8354-8383

مصطلحات موضوعية: Male, Macrocyclic Compounds, THP-1 Cells, Anti-Inflammatory Agents, 01 natural sciences, Inflammatory bowel disease, Mice, Structure-Activity Relationship, 03 medical and health sciences, Immune system, In vivo, Psoriasis, Drug Discovery, medicine, Animals, Humans, 030304 developmental biology, ADME, 0303 health sciences, Receptors, Interleukin-17, Molecular Structure, Chemistry, Drug discovery, Interleukin-17, medicine.disease, 0104 chemical sciences, Molecular Docking Simulation, proteins, macrocycles, IL 17AM, Il 17RA, chemical structure inhibitors, 010404 medicinal & biomolecular chemistry, Rheumatoid arthritis, Immunology, Molecular Medicine, Interleukin 17, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05f28315da0be7107038b135d157e95
https://doi.org/10.1021/acs.jmedchem.1c00327

المؤلفون: Andrews, Mark D., Dack, Kevin N., de Groot, Marcel J., Lambert, Maja, Sennbro, Carl J., Larsen, Mogens, Stahlhut, Martin

المساهمون: LEO Pharma A/S

المصدر: Journal of Medicinal Chemistry ; volume 65, issue 13, page 8828-8842 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.2c00422
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00422

المؤلفون: Huang, Qinhua, Johnson, Ted W., Bailey, Simon, Brooun, Alexei, Bunker, Kevin D., Burke, Benjamin J., Collins, Michael R., Cook, Andrew S., Cui, J. Jean, Dack, Kevin N., Deal, Judith G., Deng, Ya-Li, Dinh, Dac, Engstrom, Lars D., He, Mingying, Hoffman, Jacqui, Hoffman, Robert L., Johnson, Patrick S., Kania, Robert S., Lam, Hieu, Lam, Justine L., Le, Phuong T., Li, Qiuhua, Lingardo, Laura, Liu, Wei, Lu, Melissa West, McTigue, Michele, Palmer, Cynthia L., Richardson, Paul F., Sach, Neal W., Shen, Hong, Smeal, Tod, Smith, Graham L., Stewart, Albert E., Timofeevski, Sergei, Tsaparikos, Konstantinos, Wang, Hui, Zhu, Huichun, Zhu, Jinjiang, Zou, Helen Y., Edwards, Martin P.

المصدر: Journal of Medicinal Chemistry ; volume 57, issue 4, page 1170-1187 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/jm401805h
https://pubs.acs.org/doi/pdf/10.1021/jm401805h