نتائج البحث - "DNA repair"

1

Dissertation/ Thesis

DNA damage repair targeting therapeutics and predictive biomarkers for patient stratification in prostate cancer

المساهمون: University/Department: Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut

Thesis Advisors: Mateo Valderrama, Joaquín, Serra Elizalde, Violeta, Soler Prat, Concepció

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Oncologia, Oncología, Oncology, Càncer de pròstata, Cáncer de próstata, Prostate cancer, Marcadors bioquímics, Marcadores bioquímicos, Biochemical markers, Reparació de l'ADN, Reparación del ácido desoxirribonucleico, DNA repair, Ciències de la Salut

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/691466

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2

Dissertation/ Thesis

Computational studies of DNA damage and repair of alkylating agents and UV light

المؤلفون: Kranas, Hanna

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: López Bigas, Núria, González-Pérez, Abel

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: DNA damage, DNA repair mechanisms, Mutagenic processes, UV radiation, Alkylating agents, Dany genètic, Reparació de l'ADN, Processos mutagènics, Radiació ultraviolada, Alquilació de l’ADN

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/689274

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3

Academic Journal

A pan-cancer interrogation of intronic polyadenylation and its association with cancer characteristics.

المؤلفون: Liu, Liang^1,2 (AUTHOR) lliu@wakehealth.edu, Sun, Peiqing¹ (AUTHOR), Zhang, Wei^1,2 (AUTHOR) lliu@wakehealth.edu

المصدر: Briefings in Bioinformatics. Sep2024, Vol. 25 Issue 5, p1-11. 11p.

مصطلحات موضوعية: DNA repair, GENE expression, BIOMARKERS, PROGNOSIS, TUMOR classification

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4

Dissertation/ Thesis

Dealing with the main challenges of fanconi anemia molecular diagnosis and therapy

المؤلفون: Persico, Ilaria

Thesis Advisors: Bogliolo, Massimo, Pio D'Adamo, Adamo, Surrallés i Calonge, Jordi

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Anemia de Fanconi, Fanconi anemia, Reparaciò del ADN, Reparación del ADN, DNA repair, Ciències Experimentals

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/689721

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5

Academic Journal

Energy metabolism rewiring following acute UVB irradiation is largely dependent on nuclear DNA damage.

المؤلفون: Dousset, Léa^1,2 (AUTHOR), Mahfouf, Walid¹ (AUTHOR), Younes, Hadi¹ (AUTHOR), Fatrouni, Hala¹ (AUTHOR), Faucheux, Corinne¹ (AUTHOR), Muzotte, Elodie¹ (AUTHOR), Khalife, Ferial¹ (AUTHOR), Rossignol, Rodrigue^3,4 (AUTHOR), Moisan, François¹ (AUTHOR), Cario, Muriel^1,5 (AUTHOR), Claverol, Stéphane⁶ (AUTHOR), Favot-Laforge, Laure⁷ (AUTHOR), Nieminen, Anni I.⁸ (AUTHOR), Vainio, Seppo⁹ (AUTHOR), Ali, Nsrein⁹ (AUTHOR), Rezvani, Hamid-Reza^1,5 (AUTHOR) hamid-reza.rezvani@u-bordeaux.fr

المصدر: Free Radical Biology & Medicine. Feb2025, Vol. 227, p459-471. 13p.

مصطلحات موضوعية: *DNA repair, *NUCLEAR DNA, *ENERGY metabolism, *DNA damage, *OXYGEN consumption

6

Academic Journal

ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH.

المؤلفون: Liu, Yasmine J.¹ (AUTHOR), Kimura, Masaki² (AUTHOR), Li, Xiaoxu¹ (AUTHOR), Sulc, Jonathan¹ (AUTHOR), Wang, Qi¹ (AUTHOR), Rodríguez-López, Sandra¹ (AUTHOR), Scantlebery, Angelique M.L.³ (AUTHOR), Strotjohann, Keno¹ (AUTHOR), Gallart-Ayala, Hector⁴ (AUTHOR), Vijayakumar, Archana⁵ (AUTHOR), Myers, Robert P.⁵ (AUTHOR), Ivanisevic, Julijana⁴ (AUTHOR), Houtkooper, Riekelt H.^3,6,7 (AUTHOR), Subramanian, G. Mani⁵ (AUTHOR), Takebe, Takanori^2,8 (AUTHOR), Auwerx, Johan¹ (AUTHOR) admin.auwerx@epfl.ch

المصدر: Journal of Hepatology. Feb2025, Vol. 82 Issue 2, p174-188. 15p.

مصطلحات موضوعية: *DNA repair, *MENDELIAN randomization, *WESTERN diet, *LIVER cells, *PLURIPOTENT stem cells, *NAD (Coenzyme)

7

Academic Journal

Biomarkers in Ataxia-Telangiectasia: a Systematic Review.

المؤلفون: Tiet, M. Y.¹ (AUTHOR), Guțu, B.-I.¹ (AUTHOR), Springall-Jeggo, P.² (AUTHOR), Coman, D.³ (AUTHOR), Willemsen, M.⁴ (AUTHOR), Van Os, N.⁴ (AUTHOR), Doria, M.⁵ (AUTHOR), Donath, H.⁶ (AUTHOR), Schubert, R.⁶ (AUTHOR), Dineen, R. A.^7,8 (AUTHOR), Biagiotti, S.⁹ (AUTHOR), Prayle, A. P.^8,10 (AUTHOR), Group, A. T. Biomarker Working (AUTHOR), Hensiek, A. E.¹ (AUTHOR), Horvath, R.¹ (AUTHOR) rh732@medschl.cam.ac.uk

المصدر: Journal of Neurology. Feb2025, Vol. 272 Issue 2, p1-18. 18p.

مصطلحات موضوعية: *PROGNOSIS, *DNA repair, *EARLY death, *BIOMARKERS, *RESPIRATORY insufficiency

8

Academic Journal

Increased interferon I signaling, DNA damage response and evidence of T-cell exhaustion in a patient with combined interferonopathy (Aicardi-Goutières Syndrome, AGS) and cohesinopathy (Cornelia de Lange Syndrome, CdLS).

المؤلفون: Boiu, Sorina^1,2,3,4 (AUTHOR), Paschalidis, Nikolaos⁵ (AUTHOR), Sentis, George⁶ (AUTHOR), Manolakou, Theodora⁶ (AUTHOR), Nezos, Andrianos⁷ (AUTHOR), Gialitakis, Manolis⁶ (AUTHOR), Grigoriou, Maria⁶ (AUTHOR), Atsali, Erato¹ (AUTHOR), Giorgi, Melpomeni⁸ (AUTHOR), Ntinopoulos, Argirios⁹ (AUTHOR), Mavragani, Clio⁷ (AUTHOR), Makrythanasis, Periklis^5,10,11 (AUTHOR), Boumpas, Dimitrios T.^6,12 (AUTHOR), Banos, Aggelos⁶ (AUTHOR) abanos@bioacademy.gr

المصدر: Pediatric Rheumatology. 1/27/2025, Vol. 23 Issue 1, p1-15. 15p.

مصطلحات موضوعية: *DNA repair, *MEDICAL sciences, *T-cell exhaustion, *LIFE sciences, *KILLER cells

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9

Academic Journal

The role of Box A of HMGB1 in producing γH2AX associated DNA breaks in lung cancer.

المؤلفون: Settayanon, Sirapat^1,2 (AUTHOR), Chanvorachote, Pithi^3,4 (AUTHOR), Mutirangura, Apiwat¹ (AUTHOR) mapiwat@chula.ac.th

المصدر: Scientific Reports. 1/25/2025, Vol. 15 Issue 1, p1-13. 13p.

مصطلحات موضوعية: *DNA repair, *DOUBLE-strand DNA breaks, *MEDICAL sciences, *CYTOLOGY, *LIFE sciences

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10

Academic Journal

Association of Germline Pathogenic Variants in MUTYH and Other DNA Damage Response Genes With Lung Cancer Risk Among Non-Hispanic Whites and African Americans.

المؤلفون: Trendowski, Matthew R.¹ (AUTHOR) mrtrendowski@wayne.edu, Lusk, Christine M.¹ (AUTHOR), Wenzlaff, Angela S.¹ (AUTHOR), Neslund-Dudas, Christine² (AUTHOR), Purrington, Kristen S.¹ (AUTHOR), Beebe-Dimmer, Jennifer L.¹ (AUTHOR), Schwartz, Ann G.¹ (AUTHOR)

المصدر: JCO Precision Oncology. 1/24/2025, Vol. 9, p1-15. 15p.

مصطلحات موضوعية: *DNA repair, *LUNG cancer, *CANCER genes, *DISEASE risk factors, *RACE

11

Academic Journal

Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice.

المؤلفون: Scheijen, Elle EM¹ (AUTHOR), Veeningen, Naomi² (AUTHOR), Duwé, Sam³ (AUTHOR), Ivanova, Anna⁴ (AUTHOR), Van Broeckhoven, Jana² (AUTHOR), Hendrix, Sven⁵ (AUTHOR), Wilson III, David M¹ (AUTHOR) david.wilson@uhasselt.be

المصدر: Journal of Biomedical Science. 1/23/2025, Vol. 32 Issue 1, p1-16. 16p.

مصطلحات موضوعية: *DNA repair, *DNA damage, *SPINAL cord injuries, *MEDICAL sciences, *BIOLOGICAL networks

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12

Academic Journal

Multi-modal investigation reveals pathogenic features of diverse DDX3X missense mutations.

المؤلفون: Mosti, Federica^1,2 (AUTHOR), Hoye, Mariah L.¹ (AUTHOR), Escobar-Tomlienovich, Carla F.^1,2 (AUTHOR), Silver, Debra L.^1,2,3,4 (AUTHOR) debra.silver@duke.edu

المصدر: PLoS Genetics. 1/21/2025, Vol. 21 Issue 1, p1-30. 30p.

مصطلحات موضوعية: *DNA repair, *RNA-binding proteins, *RNA metabolism, *STRESS granules, *MISSENSE mutation

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13

Academic Journal

Prevalent integration of genomic repetitive and regulatory elements and donor sequences at CRISPR-Cas9-induced breaks.

المؤلفون: Bi, Chongwei¹ (AUTHOR), Yuan, Baolei¹ (AUTHOR), Zhang, Yingzi¹ (AUTHOR), Wang, Mengge¹ (AUTHOR), Tian, Yeteng¹ (AUTHOR), Li, Mo^1,2,3 (AUTHOR) mo.li@kaust.edu.sa

المصدر: Communications Biology. 1/20/2025, Vol. 8 Issue 1, p1-9. 9p.

مصطلحات موضوعية: *DNA repair, *LIFE sciences, *CRISPRS, *LOCUS (Genetics), *GENOMES, *GENOME editing

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14

Academic Journal

An agarose fluidic chip for high-throughput in toto organoid imaging.

المؤلفون: De Beuckeleer, Sarah¹, Vanhooydonck, Andres², Van Den Daele, Johanna¹, Van De Looverbosch, Tim¹, Asselbergh, Bob³, Kim, Hera⁴, Campsteijn, Coen⁴, Ponsaerts, Peter⁵, Watts, Regan² Regan.Watts@uantwerpen.be, De Vos, Winnok H.^1,6,7 Winnok.DeVos@uantwerpen.be

المصدر: Lab on a Chip. 1/21/2025, Vol. 25 Issue 2, p235-252. 18p.

مصطلحات موضوعية: *DNA repair, *CYTOLOGY, *MICROSCOPES, *AGAROSE, *ASTROCYTOMAS, *DEVELOPMENTAL biology

15

Academic Journal

The cGAS-STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts.

المؤلفون: Haj, Majd¹, Yann Frey¹, Levon, Amit¹, Maliah, Avishai¹, Ben-Yishay, Tal¹, Slutsky, Rachel¹, Smoom, Riham², Tzfati, Yehuda², Ben-David, Uri¹, Levy, Carmit¹, Elkon, Ran¹, Ziv, Yael¹, Shiloh, Yosef¹ yossih@tauex.tau.ac.il

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 1/14/2025, Vol. 122 Issue 2, p1-11. 58p.

مصطلحات موضوعية: *DNA repair, *PREMATURE aging (Medicine), *CELLULAR aging, *PERSISTENT pollutants, *INTERSTITIAL lung diseases

16

Academic Journal

Infection-induced lysine lactylation enables herpesvirus immune evasion.

المؤلفون: Tyl, Matthew D.¹, Merengwa, Victoria U.¹, Criste, Ileana M.¹ icristea@princeton.edu

المصدر: Science Advances. 1/10/2025, Vol. 11 Issue 2, p1-20. 20p.

مصطلحات موضوعية: *DNA repair, *RNA-binding proteins, *RNA regulation, *VIRAL transmission, *VIRAL proteins

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17

Academic Journal

The CYLD-PARP1 feedback loop regulates DNA damage repair and chemosensitivity in breast cancer cells.

المؤلفون: Miaomiao Zheng¹, Shuo Wang¹, Kexin Tang¹, Ruixue Kong¹, Xuemeng Wang¹, Jun Zhou¹, Yan Chen¹ yanchen@sdnu.edu.cn, Yijie Wang¹ yijiewang@sdnu.edu.cn

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 1/7/2025, Vol. 122 Issue 1, p1-21. 33p.

مصطلحات موضوعية: *EXCISION repair, *DNA repair, *DNA damage, *CANCER chemotherapy, *ALKYLATING agents

18

Academic Journal

PsDMAP1/PsTIP60-regulated H4K16ac is required for ROS-dependent virulence adaptation of Phytophthora sojae on host plants.

المؤلفون: Fan Zhang¹, Shanshan Chen¹, Can Zhang¹, Zhiwen Wang¹, Jianqiang Miao², Tan Dai², Jianjun Hao³, Xili Liu^1,2 seedling@cau.edu.cn

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 1/7/2025, Vol. 122 Issue 1, p1-30. 42p.

مصطلحات موضوعية: *DNA repair, *RNA polymerase II, *PHYTOPHTHORA sojae, *HISTONE acetylation, *HOST plants

19

Academic Journal

ATRX loss inhibits DDR to strengthen radio-sensitization in p53-deficent HCT116 cells.

المؤلفون: Qin, Lijing¹ (AUTHOR), Tang, Geng¹ (AUTHOR), Gui, Ruirui¹ (AUTHOR), Yang, Yanming² (AUTHOR), Wang, Li¹ (AUTHOR), Xu, Weiqiang¹ (AUTHOR), Tian, Hongyuan¹ (AUTHOR), Yu, Lei² (AUTHOR), Yang, Xiangshan¹ (AUTHOR) 308795903@qq.com, Wang, Zhicheng¹ (AUTHOR) zhicheng@jlu.edu.cn

المصدر: Scientific Reports. 1/4/2025, Vol. 14 Issue 1, p1-11. 11p.

مصطلحات موضوعية: *DNA repair, *CYTOLOGY, *CELLULAR aging, *LIFE sciences, *COLORECTAL cancer, *IONIZING radiation

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20

Academic Journal

Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification.

المؤلفون: Fruchard, Louna^1,2, Babosan, Anamaria¹, Carvalho, Andre¹, Manon Lang¹, Blaise Li³, Duchateau, Magalie⁴, Gianetto, Quentin Giai^4,5, Matondo, Mariette⁴, Bonhomme, Frederic⁶, Hatin, Isabelle⁷, Arbes, Hugo⁷, Fabret, Céline⁷, Corler, Enora⁷, Sanchez, Guillaume⁸, Marchand, Virginie⁸, Motorin, Yuri⁸, Namy, Olivier⁷, de Crécy-Lagard, Valérie^9,10, Mazel, Didier¹ didier.mazel@pasteur.fr, Baharoglu, Zeynep¹ zeynep.baharoglu@pasteur.fr

المصدر: eLife. 1/6/2025, p1-35. 35p.

مصطلحات موضوعية: *VIBRIO cholerae, *DNA repair, *OXIDATIVE stress, *TYROSINE, *PROTEOMICS, *TRANSFER RNA

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